Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial by Fang Wang, Chao Yang, Yue Shu, Cai-xia Lin, Yao Yao, Yue Li, Yi-miao Zhang, Xin Wang, Li-qiang Meng, Xu-yang Cheng, Gang Liu, Ming-hui Zhao, Zhao Cui

“…Abstract Background Calcineurin inhibitors, such as cyclosporine, are primary treatments for membranous nephropathy (MN). Optimizing this regimen is crucial to reduce nephrotoxicity and enhance immunological remission. …”
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Spatio-temporal dynamics and drivers of cropland ecosystem services value during the past two decades in Yangtze river economic belt, China by Hanjun Xia, Pengbo Zhang, Qi Zhang, Baofa Peng, Chenxin Zhou, Qian Zhu, Songchao Chen, Bifeng Hu

“…Moreover, the Crop-ESV showed significant spatial heterogeneity, with hot spots predominantly clustered in the west, while cold spots were primarily located in the east. …”
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WDNET-YOLO: Enhanced Deep Learning for Structural Timber Defect Detection to Improve Building Safety and Reliability by Xiaoxia Lin, Weihao Gong, Lin Sun, Xiaodong Yang, Chunwei Leng, Yan Li, Zhenyu Niu, Yingzhou Meng, Xinyue Xiao, Junyan Zhang

“…Conventional inspection methods are unable to address the issues of multi-scale defect characterization, inter-class confusion, and morphological diversity, thus limiting reliable construction quality assurance. …”
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Integration of quantum key distribution and high-throughput classical communications in field-deployed multi-core fibers by Qi Wu, Domenico Ribezzo, Giammarco Di Sciullo, Sebastiano Cocchi, Divya Ann Shaji, Lucas Alves Zischler, Ruben Luis, Paolo Serena, Chiara Lasagni, Alberto Bononi, Tetsuya Hayashi, Alessandro Gagliano, Paolo Martelli, Alberto Gatto, Paola Parolari, Pierpaolo Boffi, Davide Bacco, Alessandro Zavatta, Yixiao Zhu, Weisheng Hu, Zhaopeng Xu, Mark Shtaif, Andrea Marotta, Fabio Graziosi, Antonio Mecozzi, Cristian Antonelli

“…Abstract Quantum key distribution (QKD) is a secure communication method for sharing symmetric cryptographic keys based on the principles of quantum physics. …”
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Fe-Cu-loaded γ-Al2O3 as an efficient heterogeneous Fenton catalyst for the advanced treatment of petrochemical wastewater by Shiqi Jiang, Changyong Wu, Qi Huang, Yin Yu, Peijian Zhang, Chenjie Wang, Xiyan Ou, Min Xu

“…The catalyst was synthesized via impregnation and calcination, with preparation parameters optimized using a one-factor-at-a-time method. Under optimal conditions (Fe: 0.28 mol/L; Cu: 0.20 mol/L; 500 °C; 7 h), 50.15% TOC removal was achieved using 20 g catalyst and 13.73 mmol/L H2O2. …”
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A comprehensive comparison of third generation epidermal growth factor receptor tyrosine kinase inhibitors in the treatment efficacy and adverse events: A Bayesian meta-analysis by Jinyu Yu, PhD, Hanyu Wu, BS, Lu Yang, MD, Wei Liu, PhD, Baoshan Cao, MD, Baosheng Liang, PhD, Yangchun Gu, MD

“…Background: It is a challenge for clinicians to choose the optimal third generation EGFR-tyrosine kinase inhibitors (EGFR-TKIs) treatment for individual patients. …”
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Impact of Phenological and Lighting Conditions on Early Detection of Grapevine Inflorescences and Bunches Using Deep Learning by Rubén Íñiguez, Carlos Poblete-Echeverría, Ignacio Barrio, Inés Hernández, Salvador Gutiérrez, Eduardo Martínez-Cámara, Javier Tardáguila

“…Traditional yield prediction methods are labor-intensive, subjective, and often restricted to advanced phenological stages. …”
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Cumulative Transcutaneous Spinal Stimulation with Locomotor Training Safely Improves Trunk Control in Children with Spinal Cord Injury: Pilot Study by Liubov Amirova, Anastasia Keller, Goutam Singh, Molly King, Parth Parikh, Nicole Stepp, Beatrice Ugiliweneza, Yury Gerasimenko, Andrea L. Behrman

“…This intervention shows potential synergistic benefits, warranting further research to confirm efficacy and optimize therapeutic protocols.…”
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Seasonal Occurrence and Biodiversity of Insects in an Arid Ecosystem: An Ecological Study of the King Abdulaziz Royal Reserve, Saudi Arabia by Abdulrahaman S. Alzahrani, Moutaman Ali Kehail, Sara A. Almannaa, Areej H. Alkhalifa, Abdulaziz M. Alqahtani, Mohammed H. Altalhi, Hussein H. Alkhamis, Abdullah M. Alowaifeer, Abdulwahed Fahad Alrefaei

“…Each living organism thrives best in a habitat that provides optimal conditions for flourishing, reproduction, and distribution within a certain area. …”
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Mapping the research landscape of PET/CT in lymphoma: insights from a bibliometric analysis by Die Zhang, Jianding Peng, Yingjie Zhu, Qiang Gong, Qing Wang, Chaodong Xiang, Hanjian Du, Xiaofei Hu

“…Original articles and reviews in English on PET/CT in lymphoma staging, response assessment, or prognosis were included, while case reports, meeting abstracts, and editorials were excluded. …”
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Synergistic enhancement of sugar beet root physico-mechanical properties using magnetically treated water and potassium nano-fertilizers for sustainable farming by Naema E. M. Salama, Mahmoud A. Abdelhamid, Muhammad Mayhoub, Alfadhl Y. Alkhaled, Hassan A. A. Sayed, Mahmoud Younis, Salwa Hassan Abdou

“…This approach highlights the potential of MIW and potassium nano-fertilizers to optimize sugar beet cultivation, offering a sustainable strategy to support future agriculture practices while minimizing environmental impact.…”
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Development and validation of a nomogram for predicting immunotherapy outcomes in lung cancer patients using clinical and blood biomarkers by Ting Ouyang, Fei Zhang, Yan Yang, Tianwei Luo, Ao Chen, Ning Han, Jun Qian, Xiaoyuan Chu, Chao Chen, Mi Yang

“…Thus, developing accurate and practical prognostic tools is essential to optimize treatment decision-making. Methods This retrospective study analyzed 436 lung cancer patients treated with ICIs, who were randomly divided into training (70%) and validation (30%) cohorts. …”
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Manufacturing Process Development for <i>Bison bison</i> Organ-Specific Lyophilized Extracts: Formulation and Benchmarking of Antioxidant Activities for Nutraceutical Preparations by Alexandre Porcello, Kim Girardet, Basste Hadjab, Kelly Lourenço, Corinne Scaletta, Philippe Abdel-Sayed, Nathalie Hirt-Burri, Lee Ann Applegate, Alexis E. Laurent

“…The first objective of this study was to develop an optimized and function-oriented manufacturing process for stabilized organ-specific extracts of American buffalo (<i>Bison bison</i>). …”
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Second-line Chemotherapy for Advanced Bladder Cancer: Taxanes Versus Vinflunine by Bilgin Demir, Ali Aytaç, Gökhan Çolak, Onur Yazdan Balçık, Ömer Acar

“…Vinflunine is the only agent approved by the European Medicines Agency for this setting, while taxanes are widely used off-label based on phase 2 data. …”
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Preparation and decolorization of sapindus mukurossi extract and its application in sebum-control shampoos by Kaibo Wan, Ling Ma, Diansong Chen, Zhizhen Li, Christos C. Zouboulis, Kuan Chang, Jing Wang

“…No significant changes in the skin moisture content and transepidermal water loss (TEWL) are observed within four weeks after using the product, while the scalp sebum level is significantly reduced. …”
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Evaluation of the safety and efficacy of ABO non-identical apheresis platelets with reduced plasma transfusion by DIAO Ronghua, RUAN Qianying, BAI Lu, ZHANG Hong, WANG Zerong, FU Lei, WANG Shichun

“…[Objective] To evaluate the safety and efficacy of ABO non-identical platelets with reduced plasma (ABO-NPRP) transfusion in patients with hematological diseases. [Methods] A retrospective analysis was conducted on 52 therapeutic doses of apheresis platelets with reduced plasma prepared at Chongqing Blood Center of the Chinese People's Liberation Army. …”
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Altered brain dynamics in post-stroke cognitive and motor dysfunction by Xiaoying Liu, Guihua Song, Xiaoyun Zhuang, Ying Zhang, Xiaoyang Wang, Yin Qin, Yin Qin

“…Neuromodulation strategies can be optimized by HMM-derived brain states in the future.…”
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Unveiling etiology and mortality risks in community-acquired pneumonia: A machine learning approach by Alaa Ali, Ahmad R. Alsayed, Nesrin Seder, Yazun Jarrar, Raed H. Altabanjeh, Mamoon Zihlif, Osama Abu Ata, Anas Samara, Malek Zihlif

“…Traditional diagnostic methods have limitations, prompting the use of machine learning (ML) to enhance diagnostic precision and treatment strategies. …”
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Cortical thickness and structural covariance network alterations in cerebral amyloid angiopathy: A graph theoretical analysis by Yijun Lin, Bin Gao, Yang Du, Mengyao Li, Yanfang Liu, Xingquan Zhao

“…Results: CAA patients exhibited significant alterations in small-world properties, with decreased Gamma (p = 0.002) and Sigma (p < 0.001), suggesting a shift toward a less optimal network configuration. Local efficiency was significantly different between groups (p = 0.045), while global efficiency remained unchanged (p = 0.127), indicating regionally disrupted rather than globally impaired network efficiency. …”
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Chronic urticaria and vitamin D supplementations: a systematic review by Ayesha Siddiqui, Aruna Bai, Haresh Kumar, Yash Roop Mandhwani, Anjali Bai, Priya Bai, Neha kumar, F. N. U. Muskan, Sumaiya Jatoi, Zulfiqar Ali, Abida Parveen

“…Conclusion Vitamin D supplementation may serve as a safe, accessible adjunct to standard CU treatment, particularly for those with confirmed deficiency. While evidence suggests potential benefits, further high-quality RCTs are needed to establish causality, optimal dosing, and long-term efficacy.…”
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