Early-onset difficult-to-treat rheumatoid arthritis: proposal of data-driven predictors and temporal threshold by Pablo Rodriguez-Merlos, Jose Luis Cabrera-Alarcón, Virginia Ruiz-Esquide, Chafik Alejandro Chacur, Raimon Sanmartí, Eugenio De Miguel-Mendieta, Jose María Álvaro-Gracia, Alejandro Balsa, Chamaida Plasencia-Rodríguez, Marta Novella-Navarro

“…Abstract Background While risk factors for difficult-to-treat rheumatoid arthritis (D2TRA) have been studied in recent years, no studies have determined if there are differences between early and late developers of D2TRA. …”
Get full text

Development and Implementation of a Self-Management Intervention Program for Patients with Esophageal and Gastric Varices Secondary to Liver Cirrhosis Under Collaborative Care by Li M, Xie XE, Qin X, Wu T, Bian ZL

“…This study provides a strong foundation for future research to optimize and scale similar interventions in diverse clinical settings.Keywords: Endoscopic treatment, esophageal and gastric varices, liver cirrhosis, self-management, collaborative care, intervention…”
Get full text

Research on innovative development path of oil and gas pipeline networks to facilitate the construction of new energy systems by Zhen WANG, Yinghao KONG

“…This expansion is essential for establishing close interconnections with other energy sources while ensuring the efficient transmission of oil and gas. …”
Get full text

Family Experiences, Needs, and Perceptions in Home-Based Hospice Care for Patients With Terminal Cancer: Meta-Synthesis and Systematic Review by Xin Ming Deng, Kanokwan Hounsri, Violeta Lopez, Wilson Wai-San Tam

“… Abstract BackgroundHome-based hospice care offers patients with terminal cancer the comfort of receiving care in a familiar environment while enabling family members to provide personalised support. …”
Get full text

A METHODOLOGICAL APPROACH TO DESIGNING EXPERIMENTS WHEN DEALING WITH IDENTIFICATION TESTS FOR MEDICINAL PRODUCT COMPONENTS (AS ILLUSTRATED BY ASCORBIC ACID) by Yu. B. Purim, M. L. Kruglyakova, L. N. Bulanova, M. V. Agapkina, L. N. Stronova, T. N. Bokovikova, E. P. Gernikova

“…The whole complex of the studies performed helped to determine qualitative reactions and optimal conditions for identification testing of the analysed substance.…”
Get full text

The impact of social media addiction on depression among university students in Wuhan, China: a longitudinal study by Yang Luo, Ling Liang, Huimin Zhou, Xinxin Qi, Jiale Xu, Heng Meng

“…Abstract Objective The aim of this study was to investigate the association between social media addiction and depression among university students of different genders in Wuhan, China, and also to explore the effect of social support on depression in the context of social media addiction. Methods Three waves (2020–2023) of psychological optimism and health data were analyzed. …”
Get full text

Modern clinical portrait of ovarian cancer patient in the Novosibirsk region by A. V. Tarkhov, M. A. Goncharov, A. V. Tereschenko, N. Yu. Zvezdina, N. A. Buksel, D. K. Ukolova, L. Yu. Konovalova, D. K. Nikitina, D. V. Morozov, M. S. Selyakova

“…More than half of the patients with ovarian cancer (56.2 %) either had no births at all (13.8 %) or had only one birth (42.4 %), while 68.2 % had a history of abortions. The comorbidities of arterial hypertension, diabetes mellitus, and obesity were common in ovarian cancer patients. …”
Get full text

Diagnostic accuracy of rapid on-site evaluation in subtyping lung cancer via bronchoscopic biopsy by Shuang Yan, Hua Jiang, Li Gong, Lei Pan, Faguang Jin

“…ROSE remains critical for optimizing biopsy workflows and reducing repeat procedures.…”
Get full text

Bidirectional association between grip strength and cognitive function in Chinese older adults: a nationwide cohort study by Jinfu Wang, Quanming Cui, Xue Xu, Guan Yang

“…Grip strength was measured using a standardized dynamometer, while global cognitive function was assessed through mental intactness and episodic memory metrics. …”
Get full text

Survey of venous thromboembolism prophylaxis in trauma patients: current prescribing practices and concordance with clinical practice guidelines by Elliott R Haut, Allison E Berndtson, Todd W Costantini, David Spain, Matthew E Kutcher, Nathan Polite, Kaitlin M Alexander, Charles Caleb Butts, Yan-Leei Larry Lee, Jon D Simmons

“…The purpose of this study was to characterize current dosing practices and timing of initiation of pharmacological VTE chemoprophylaxis at trauma centers.Methods This was an international, cross-sectional survey of trauma providers. …”
Get full text

The Effects of Three Phenolic Substances on the Growth and Digestive Physiology of the Fall Armyworm <i>Spodoptera frugiperda</i> (Lepidoptera: Noctuidae) by Jin-Yan Lv, Ya-Nan Deng, Xiao-Rong Liu, Dan Niu, Wan-Shu Zhang

“…Screening natural antifeedants from the secondary metabolites of plants may provide efficient alternative control methods for the integrated management of invasive pests. …”
Get full text

Steal Syndrome in Free Flap Microvascular Reconstruction of the Lower Extremity: Systematic Review of Incidence, Risk Factors, and Surgical Management by Georgios Karamitros, Ilias Iliadis, Raymond A. Pensy, Gregory A. Lamaris

“…In the present study, we aim to comprehensively evaluate the occurrence and management of steal syndrome in free flap reconstruction of the lower extremities. <b>Methods</b>: A thorough literature search was conducted across the MEDLINE, Embase, Cochrane Library, and Scopus databases up to 29 January 2025. …”
Get full text

The diagnostic accuracy of the ESC 0/1-hour algorithm in non-ST-segment elevation myocardial infarction in a crowded emergency department: a real-world experience from a single-cen... by Emre Kudu, Ahmet Enes Kucukardali, Mustafa Altun, Ümit Öztürk, Erhan Altunbaş, Sinan Karacabey, Erkman Sanri, Arzu Denizbasi

“…Its implementation could optimize ED resource utilization and improve clinical outcomes. …”
Get full text

Adaptation potential of medical students in distance learning by O. V. Toussova, O. V. Pavlova

“…There are practically no studies on this topic, which explains the novelty and relevance of this work.Methods and materials. The article is devoted to the study of adaptive features of medical students in distance learning. …”
Get full text

Efficacy and Safety of Transcatheter Tricuspid Valve Replacement in Patients With Moderate to Severe Tricuspid Regurgitation: A Systematic Review and Meta‐Analysis on Clinical Outc... by Pouria Azami, Alireza Hosseinpour, Jahangir Kamalpour, Farshad Rajabi, Iman Razeghian‐Jahromi, Sarvenaz Farhangdoost, Reza Golchin Vafa, Ghazaleh Bagheri

“…Conclusion TTVR presents a promising treatment alternative for high‐risk patients with severe TR, demonstrating high technical success, favorable clinical outcomes, and significant echocardiographic improvements. While the procedure is associated with low in‐hospital and 1‐year mortality, further studies are needed to evaluate long‐term outcomes and optimize patient selection for this emerging therapy.…”
Get full text

Demographic and clinical associations with miscarriage and unsuccessful conception attempts among female Syrian refugees in Lebanon by Gladys Honein- AbouHaidar, Hady Naal, Asmaa El Dakdouki, Zahraa Chamseddine, Dalia Sarieddine, Hani Tamim, Tania Bosqui, Fouad Fouad, Sara Ibrahim, Zahi Abdul Sater, Shadi Saleh

“…This study focuses on examining sociodemographic and clinical factors associated with miscarriage and unsuccessful conception among this population. Methods This cross-sectional study is part of the Self-Efficacy and Knowledge Trial, which aims to enhance SRH and family planning among Female Syrian refugees in humanitarian settings. …”
Get full text

Anorexia-cachexia syndrome in cancer patients: pathogenetic aspects and treatment options by A. V. Snegovoy, V. B. Larionova, I. V. Kononenko

“…First, it will allow optimizing monitoring of cancer patients predisposed to CACS development during anticancer treatment. …”
Get full text

Computational simulation and mathematical modelling of thermal performance and energy enhancement of integrated infrared with hot air heated system by Hany S. El-Mesery, Ahmed H. ElMesiry, Oluwasola Abayomi Adelusi, Zicheng Hu, Sara Elhadad

“…Despite their widespread use, energy-efficient drying methods for heat-sensitive medicinal herbs, particularly peppermint leaves, remain underexplored, and conventional techniques often lead to quality degradation and high-energy consumption. …”
Get full text

Naphthalimide-polyamine conjugates: a promising avenue for targeted anticancer therapy by Zhiyong Tian, Luyao Tian, Chaojie Wang

“…These methods provide a practical strategy for future cancer therapies aimed at overcoming adaptive resistance.…”
Get full text

Corticospinal Intermittent Theta Burst Stimulation Propelling Sensorimotor Function Recovery in Complete Spinal Cord Injury: Protocol for a Randomized Controlled Trial by Deeksha Patel, Rohit Banerjee, Kamran Farooque, Deepak Gupta, Bhavuk Garg, Nand Kumar, Kanwal Preet Kochhar, Suman Jain

“…In addition, to determine the optimal site for stimulation, groups were further subdivided into motor cortex, spinal cord, and combined. …”
Get full text