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HPLC-UV method development and validation for anticancer drug sorafenib and the co-prescribed drug dexamethasone: application to pharmacokinetic evaluation of sorafenib nanoformula...
Published 2025-04-01“…The analytes were extracted with acetonitrile using the protein precipitation method. The chromatographic parameters were optimized, and the method was validated as per the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines. …”
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3223
Characteristics associated with optimal blood sugar in individuals living with type 2 diabetes in hard-to-reach rural communities: results of a cross-sectional study in Esmeraldas,...
Published 2025-03-01“…Furthermore, older age (aOR = 1.03, 95%CI: 1.01–1.05, p = 0.006), living in an urbanised setting (aOR = 2.04, 95%CI: 1.22–3.40, p = 0.006) and unemployment (aOR = 0.48, 95%CI: 0.25–0.94, p = 0.031) were also linked to optimal blood glucose levels. While perceived social support in this population was moderate (median = 2.33, on a scale of 1 to 4), high family support appeared to reduce optimal glycaemic levels (aOR = 0.35, 95%CI: 0.18–0.70, p = 0.003). …”
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3224
Towards Efficient Object Detection in Large-Scale UAV Aerial Imagery via Multi-Task Classification
Published 2025-01-01“…In the large-scale UAV images and ASDD dataset, our proposed method increases the detection speed by more than 30% and 130%, respectively, while maintaining good object detection performance.…”
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3225
Asymmetric Double-Sideband Composite Signal and Dual-Carrier Cooperative Tracking-Based High-Precision Communication–Navigation Convergence Positioning Method
Published 2025-05-01“…By organically integrating an embedded signal into the original positioning signal, the code loop is optimized via fuzzy control, while the ADCLS signal is processed as an asymmetric double-sideband signal for joint signal extraction. …”
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3226
RS, S (+) - and R (−)-ibuprofen cocrystal polymorphs: Vibrational spectra, XRD measurement and DFT calculation studies
Published 2025-02-01“…We found that the melt recrystallization method can generate cocrystal form A, while the solvent drop grinding method and solution evaporation method can generate cocrystal form B. …”
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3227
An Efficient Hybrid Meta-heuristic Algorithm for Solving Capacitated Vehicle Routing Problem
Published 2025-06-01“…When we compare with old methods, our algorithm finds the same optimal solutions but needs about 80 percent less calculations. …”
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3228
Study of mechanical and physical properties of pineapple leaf fiber and coffee husk filler reinforced polymer composite using response surface method
Published 2025-09-01“…This study fabricates composite samples using the hand layup method, and the Response Surface Methodology is used to optimize the experimental design. …”
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3229
A novel two-stage feature selection method based on random forest and improved genetic algorithm for enhancing classification in machine learning
Published 2025-05-01“…Then, the improved genetic algorithm is used to search for the global optimal feature subset further. This process introduces a multi-objective fitness function to guide the feature subset, minimizing the number of features in the subset while enhancing classification accuracy. …”
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3230
A Simple Real-Time Method for Detecting Low Performance in Wet High-Intensity Magnetic Separators (WHIMSs) Due to Coil Malfunction
Published 2025-05-01“…Wet High-Intensity Magnetic Separators (WHIMSs) have become well established in mineral processing operations by efficiently separating particles based on their magnetic properties. While the existing literature extensively discusses WHIMS performance under varying operational conditions, there is a notable absence of attention to the degradation of coils over time and methods for its detection. …”
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Evaluating integrated development environments using the TOPSIS method and Schweizer-Sklar power aggregation operator: implications for university students’ psychological managemen...
Published 2025-07-01“…Finally, numerical examples are presented to compare the proposed ranking results with existing ones, demonstrating the effectiveness of these methods in optimizing IDE selection and supporting students' psychological well-being.…”
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3232
Method for limiting the peak factor using an additional compensation signal in a system with orthogonal frequency division multiplexing for a Gaussian channel
Published 2024-10-01“…Statistical radio engineering and computer modeling methods are used according to optimal signal reception theory.Results. …”
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3233
Greens assessment of RP-UPLC method for estimating Triamcinolone Acetonide and its degraded products compared to Box-Behnken and Six Sigma designs
Published 2024-12-01“…The Box-Behnken design was developed to efficiently determine the optimal chromatographic conditions while minimizing the required trials. …”
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A robust method to simultaneously place sensors and calibrate parameters for urban drainage pipe system models using Bayesian decision theory
Published 2025-12-01“…However, there is often the case that sensors are not available when model calibration is required, and hence sensor placing and model calibration need to be simultaneously considered in many engineering practices. While many methods are available for either sensor deployment or model calibration with given observation data, there is a lack of approach to consider these two objectives simultaneously. …”
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Use of a combined method of photo-electrocoagulation-oxidation for simultaneous removal of Ni, CN, Zn, and Cu from synthesized mine wastewater
Published 2025-09-01“…The highest simultaneous elimination of the target pollutants was attained when stainless steel and iron were employed as anode electrodes, while aluminum and graphite served as cathodes. This optimal removal was achieved under conditions including the addition of 4 mg/L hydrogen peroxide, an ozone flow rate of 3 L/min, current density of 15 mA/cm², pH = 10, process duration of 10 min, and an electrode spacing of 5 cm in batch mode. …”
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3236
Extraction Method and Crude Drug-to-Solvent Ratio Effects on the Antioxidant Properties and Physicochemical Profile during Storage of a Polyherbal Formulation Extract
Published 2024-01-01“…The herbal mixture was extracted using Decoction A, Decoction B, and infusion methods at crude drug-tosolvent ratios of 1:10, 1:20, and 1:100. …”
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Lagrange multiplier selection based on SATD for H.265/HEVC
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3238
Useful shadow: A new independent metric to evaluate the overshadowing buildings
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3239
Collaborative filtering based on nonnegative/binary matrix factorization
Published 2025-07-01Get full text
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3240
Modeling and Dynamic Parameterized Predictive Control of Dissolved Oxygen in Dual−Tank Bioreactor Systems
Published 2025-06-01Get full text
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