SLC44A2 negatively regulates mitochondrial fatty acid oxidation to suppress colorectal progression by blocking the MUL1-CPT2 interaction by Ying Yang, Longlong Zheng, Jiaxing He, Tao Wu, Haicheng Yang, Bo Zhang, Shuai Zhou, Yueyue Lu, Xianli He, Jibin Li, Nan Wang

“…In the present investigation, we observed a significant reduction in SLC44A2 expression in colorectal cancer (CRC), and low SLC44A2 expression was closely associated with poorer survival of CRC patients. …”
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Fracture Analysis of Brittle Materials Based on Nonlinear FEM and Application in Arch Dam with Fractures by Yuanwei Pan, Yaoru Liu, Zhixiong Cui, Xin Chen, Qiang Yang

“…Based on deformation reinforcement theory coming from elastoperfect plastic theory, unbalanced force is proposed to predict initiation and propagation of cracks. Unbalanced force is the driving force of time-dependent deformation according to Perzyna’s viscoplasticity theory. …”
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Gut microbiome and metabolome interactions in Crohn’s disease: mechanistic insights into exclusive enteral nutrition-induced remission by Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Quan Zhou, Quan Zhou, Mengli Xue, Mengli Xue, Mengli Xue, Mengli Xue, Xing Yu, Xing Yu, Xing Yu, Xing Yu, Xue’e Chen, Xue’e Chen, Xue’e Chen, Xue’e Chen, Jintong Chen, Jintong Chen, Jintong Chen, Jintong Chen, Chengdang Wang, Chengdang Wang, Chengdang Wang, Chengdang Wang

“…Importantly, EEN therapy was associated with a reduction in oxidative stress and an improvement in gut barrier function.ConclusionThis study comprehensively integrates microbiome and metabolome analyses, providing new insights into the mechanism of action of EEN therapy in CD. …”
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Effect of extreme pH levels on early larval stages of the Pacific abalone (Haliotis discus hannai Ino, 1953) by Dian Yuni Pratiwi, Irfan Zidni, Mi-Jin Choi, Young Dae Oh, Tae Min Kim, Han Kyu Lim

“…However, at 30 hpf, a significant reduction in the oxygen consumption rate was observed only at pHs 9 and 10 (p < 0.05). …”
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<i>Colletotrichum capsici</i>-Induced Disease Development in Postharvest Pepper Associated with Cell Wall Metabolism and Phenylpropanoid Metabolism by Yunfen Liu, Qian Song, Feilong Yin, Yuanli Liang, Mubo Song, Meiying He, Liang Shuai

“…These insights highlight the need for early intervention strategies to mitigate postharvest losses by targeting pathogen-induced stress responses and cell wall integrity preservation.…”
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Analysis of the effect of groove-type micro-texture on the lubrication performance of stator rubber in screw pumps under different well-site environments by Xinfu Liu, Yi Sun, Shousen Zhang, Chao Zhou, Chunhua Liu, Zhongxian Hao, Songbo Wei

“…The asymmetric groove structure augments the hydrodynamic lubrication effect of the micro-texture, increases the oil film load-bearing capacity, and improves friction and drag reduction performance. As the alignment inclination angle increases, the maximum pressure on the woven oil film surface first increases and then decreases, peaking at an inclination angle of 60° As shale fluid viscosity and slip velocity increase, the maximum stress on the wall surface of the asymmetric textured oil film rises, and the hydrodynamic pressure lubrication effect becomes more pronounced. …”
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Effects of a sedentary behaviour intervention in emergency dispatch centre phone operators: a study protocol for the SECODIS randomised controlled cross-over trial by Bruno Pereira, Frederic Dutheil, Jeannot Schmidt, Martial Mermillod, Jean-Baptiste Bouillon-Minois, Marion Trousselard, Daniel Pic, Maëlys Clinchamps, Thierry Taillandier

“…To our knowledge, there is no intervention study on the reduction of occupational sedentary behaviour in a real work situation and its impact on health and biomarkers of stress. …”
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Rheology of rock–ice avalanche in a periodic chute flow by Zhiping Sun, Zhibo Dong

“…Depth-resolved profiles of six key parameters—velocity, solid volume fraction, shear stress, normal stress, shear rate, and inertia number—were recorded during steady flow conditions. …”
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Lithium-ion battery state-of-charge estimation based on a dual extended Kalman filter and BPNN correction by Likun Xing, Liuyi Ling, Xianyuan Wu

“…The results of acceptable SOC estimation are achieved using the DEKF to estimate the battery SOC and simultaneously update model parameters online, while the SOC estimation error is in real-time predicted by the trained BPNN. To further reduce the SOC estimation error, the SOC estimated by the DEKF is corrected by adding the predicted estimation error. …”
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Assessment of geomechanical properties of Sakhalin shelf reservoirs based on modeling results by V. Yu. Kerimov, G. N. Potemkin, A. K. Shatyrov

“…This initiates the formation of a local stress field, launches changes in the degree of fracture openness, and determines the secondary porosity and permeability of rocks. 3D modeling allowed us to calculate predicted permeability for each stratigraphic horizon. …”
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A New Method for Accelerated Aging of Nanoparticles to Assess the Colloidal Stability of Albumin-Coated Magnetic Nanoparticles by Boris Nikolaev, Ludmila Yakovleva, Viacheslav Fedorov, Natalia Yudintceva, Daria Tarasova, Elizaveta Perepelitsa, Anastasia Dmitrieva, Maksim Sulatsky, Sivaprakash Srinivasan, Shirish H. Sonawane, Anusha Srivastava, Sharad Gupta, Avinash Sonawane, Stephanie E. Combs, Maxim Shevtsov

“…A method for the accelerated temperature stress “aging” of magnetic nanosized suspensions is proposed for the rapid assessment and prediction of the colloidal stability over time of nanosized iron oxide suspensions stabilized by albumin HSA. …”
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Assessing climate and land use impacts on surface water yield using remote sensing and machine learning by Amanuel Kumsa Bojer, Muluneh Woldetsadik Abshare, Fitsum Mesfin, Ayad M. Fadhil Al-Quraishi

“…This study also showed a reduction in lateral flow and higher evapotranspiration levels in 2000 and 2017. …”
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Implications of thermal stratification and radiative heat flux in blood-based ternary and dihybrid nanomaterial flow through a stretchable cylinder by Muzher Saleem, Ghada A. Khouqeer, Fazal Haq, Naglaa AbdelAll, Arshad Hussain, Mohammed Sallah

“…A reduction of 4 % in the skin friction coefficient of THNF compared to HNF is noticed. …”
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Multi-objective optimization of urban block configuration to enhance outdoor thermal comfort: A case study of district 12, Tehran by Mozhgan Mousaeipour, Haniyeh Sanaieian, Mohsen Faizi, Ainaz Alafchi, S. M. Amin Hosseini

“…Compared to the worst-performing configuration, this solution achieved an average reduction—during the time interval from 7:00 AM to 8:00 PM—of 10.26 °C in Mean Radiant Temperature (MRT), 3.48 °C in Universal Thermal Climate Index (UTCI), 3.77 °C in Physiological Equivalent Temperature (PET), and 0.49 °C in Air Temperature (TA). …”
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Emotional burnout among medical stuff of a neurosurgery center: analysis of prevalence, structure and risk factors by A. V. Rehush, M. V. Markova, V. A. Pliekhov, T. P. Yavorska

“…The prevalence of emotional burnout among medical staff of the neurosurgery center has been established for various components of this phenomenon: “Emotional exhaustion” – 52.0 %, “Depersonalization” – 40.0 %, “Reduction of personal achievements” – 50.0 %, indicating a high level of stress and negatively affecting the mental health of the selected contingent. …”
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Acute Dermatotoxicity of Green-Synthesized Silver Nanoparticles (AgNPs) in Zebrafish Epidermis by Grace Emily Okuthe, Busiswa Siguba

“…A 96 h assay revealed a biphasic response: initial mucin hypersecretion at lower AgNP levels, suggesting an early stress response, followed by a concentration-dependent collapse of mucosal integrity at higher exposures, with mucus degradation and alarm cell depletion. …”
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Impacts of diffusion and chemical reaction on heat transfer in Casson nanofluids flow over a flat plate with accretion by J. Jayaprakash, Vediyappan Govindan

“…Conversely, more chemical reactions reduce the heat transfer rate. Concentration reduction can inhibit convective heat and mass transfer, which can reduce the efficiency of systems. …”
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A randomized cross-over study of the acute effects of running 5 km on glucose, insulin, metabolic rate, cortisol and Troponin T. by Boris Keselman, Marta Vergara, Sofia Nyberg, Fredrik H Nystrom

“…<h4>Conclusions</h4>Relatively short running-races can apparently induce a reduction in insulin sensitivity that is not fully compensated by concomitantly increased insulin secretion intended to ensure euglycemia. …”
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The independent and interactive effects of heavy metal pollution and vitamin D deficiency on early kidney injury indicators: analysis of the National Health and Nutrition Examinati... by Shuhui Jing, Yuan Ge, Juan Pan, Pei Chang, Xi Qiao

“…Vitamin D has been implicated in mitigating the oxidative stress and inflammatory reactions triggered by heavy metal exposure. …”
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Psychodrama: implementation, study design and effectiveness: a systematic review by Jesús Maya, Miriam Pérez-Berbel, Laura Giraldo-Arroyave, Irene Hurtado

“…In relation to the effectiveness of psychodrama, positive and significant results were found, for example, in the reduction of post-traumatic stress levels, the empowerment of women in vulnerable situations, improvement in the quality of life and symptoms of patients with schizophrenia, or improvement in antisocial behavior in adolescents. …”
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