Low Dose Pregabalin Improves Gastrointestinal Symptoms of Crohn’s Disease by Antonio Maria D’Onofrio, Federica Di Vincenzo, Gaspare Filippo Ferrajoli, Franco Scaldaferri, Giovanni Camardese

“…Following the beginning of the treatment, the patient rapidly reported an improvement in the overall clinical symptoms as well as a better management of psychic and physical anxiety with a marked reduction in diarrheal discharges under stress at work. …”
Get full text

Comprehensive cognition of yak (Bos grunniens) AIFM2 gene and its anti-ferroptosis role in bisphenol A-induced fetal fibroblast model by Yueyue Li, Hongmei Xu, Zifeng Ma, Qiao Li, Yan Xiong, Xianrong Xiong, Jian Li, Daoliang Lan, Wei Fu

Get full text

Comparison of sternocleidomastoid and trapezius muscle stretches in the management of symptomatic non specific cervical pain by Janagiraman R, Shenbaga Sundaram Subramanian, Srivatsan M, Surya Vishnuram, Saad Suleman Alfawaz, Kavitha Ramanathan, Fadwa Alhalaiqa, Syed Abudaheer K, Naresh Bhaskar Raj

“…Result: Both stretching interventions led to a significant reduction in pain and improved functional ability (p < 0.001). …”
Get full text

New Findings on the Survival of <i>Durusdinium glynnii</i> Under Different Acclimation Methods to Low Salinities by Barbara de Cassia S. Brandão, Jéssika L. de Abreu, Deyvid Willame S. Oliveira, Clarissa Vilela F. da Silva Campos, Ingrid M. Thó de Aguiar, Pedro R. de Sena, Alfredo O. Gálvez, Carlos Yure B. Oliveira

“…The S2 strategy enabled adaptation to salinities as low as 16 g L⁻¹, maintaining higher cell densities compared to the S5 method. Gradual salinity reduction also influenced cellular morphology: below 12 g L⁻¹, a predominant shift occurred from motile forms (mastigotes) to non-motile spherical structures (coccoid), suggesting an adaptive response to osmotic stress, gradually reducing the growth rate due to the lower reproductive rate of coccoid cells, as previously reported in studies. …”
Get full text

NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target by Meng Wang, Meng Wang, Zhibin Xie, Yuanyuan Tan, Yan Zhou, Tingting Zhang, Yuqing Du, Huan Wu, Lili Zhou, Jian Ge

“…Furthermore, we constructed an interaction network and predictive model for NAP1L5, complemented by an assessment of its role in immune infiltration and drug sensitivity. …”
Get full text

A genetic variant of the glutamate-cysteine ligase catalytic subunit is associated with susceptibility to ischemic stroke in the Chinese population by Tao Liao, Yin-Hua Weng, Jiang He, Mei-Rong Chen, Yu Chen, Zhong-Quan Qi, Zheng-Mian Zhang

“…The identified rs12524494 GG may serve as a potential biomarker for predicting IS susceptibility in the Chinese population, which could inform personalized medicine approaches for stroke prevention and treatment.…”
Get full text

Investigation of fracture properties of mode I fracture in heat-treated granite by Shaoqing Niu, Jinwen Wu, Shuping Chen, Jinchang Zhao

“…The findings have potential applications in predicting rock failure and stability in fields such as geothermal energy development, tunneling, and deep underground mining.…”
Get full text

Damage response and influencing factors of plastic damage caused by hydraulic fracturing of shale by Zhonghui SHEN, Lei ZHOU, Dong LIN, Zhiguo GUO, Ziyi WANG, Xijian LI

“…Specifically, the size of the plastic zone is less affected by the Young’s modulus and Poisson's ratio of the rock, and is positively correlated with wellbore diameter and internal fluid pressure, while negatively correlated with confining pressure and rock tensile strength. ④ At the scale of on-site engineering, the plastic zone of shale hydraulic fracturing presents an elliptical distribution, and the major axis is in the direction of the maximum horizontal principal stress. The research results have important theoretical and practical significance for predicting the fracturing pressure and fracturing construction design of deep rock hydraulic fracturing.…”
Get full text

Evaluating the efficiency of teaching basic cardiopulmonary resuscitation among medical university students in Ukraine by H.Yu. Tsymbaliuk, A.M. Chervatiuk, V.O. Krylyuk

“…The data obtained underscore the need for standardization of BCPR training and changes in approaches to practical training, as well as the importance of using simulation methods in the educational program. It is shown that to improve the quality of education and the confidence of students in their actions in future professional activities, it is critically necessary to add more simulation technologies and psychological preparation to avoid stress when providing assistance in real-life BCPR situations.…”
Get full text

Are they looking for support? Mental health and trauma awareness as predictors of mental health help-seeking behaviour among young adults and adolescents in Bangladesh, Egypt, Ghan... by Maxwell Peprah Opoku, Rahemeen Yusuf, Shakila Nur, Ebenezer Mensah Gyimah, Lilian Frimpomaa, Eleana Charalambous, Yasmin A. Salem, Mokhtar A. Elkayal, Aisha A. Abosrea, Tawasol Babiker, Mahra Murad Alblooshi, Erin September, Nada Obaid, Daniel Miezah, Ashraf Moustafa

Get full text

COMPARATIVE ANALYSIS OF TISSUE EXERTION OF MUCOUS MEMBRANES DURING DIFFERENT STAGES OF TENSION IN PERFORMING ON CLOTTING OPERATION by D.V. Kaplun, V.M. Skrupnik, S.O. Stavitsky

“…At the same time, the index of tissue voltage reduction is directly dependent on the tensile strength and is 208.08 + 19.2 Pa. …”
Get full text

Multiscale and Failure Analysis of Periodic Lattice Structures by Young Kwon, Matthew Minck

“…Then, the downscaling process is applied to the continuum models to determine the stresses in actual lattice members, which were applied to the stress and stress gradient based failure criterion to predict failure. …”
Get full text

Validity and Reliability of the Multidimensional Scale of Perceived Social Support (MSPSS) in Greek Secondary School Students by Vasiliki Efthymiou, George P. Chrousos, Kalliopi Kounenou, Antonios Kalamatianos, Christos Pezirkianidis, Markos Korelopoulos, Charikleia Stefanaki, Ntina Kourmousi

Get full text

GC-MS Phytochemical Profiling, Antidiabetic, and Antioxidant Activities of Khaya senegalensis Stem Bark and Azadirachta indica Leaves Extracts in Rats by Rania Mustafa Ahmed, Asaad Khalid, Syam Mohan, Sakina Yagi, Hasseba Ahmed Saad, Nada Kamal Bayoumi, Amna Ali, Karam Ahmed El-Sharkawy, Hassan A. Alhazmi, Mohammed Albratty, Sadique A. Javed, Shahnaz Sultana, Abdulkarim M. Meraya

“…However, A. indica leaf extract showed greater reduction (52%) than K. senegalensis stem bark extract (37%). …”
Get full text

Significance of Omega-3 Fatty Acids in the Prophylaxis and Treatment after Spinal Cord Injury in Rodent Models by Piotr Wojdasiewicz, Łukasz A. Poniatowski, Paweł Turczyn, Justyna Frasuńska, Agnieszka Paradowska-Gorycka, Beata Tarnacka

“…On the other hand, the therapeutic properties (post-SCI) include the increased production of endogenous antioxidants such as carnosine and homocarnosine, the maintenance of elevated GSH concentrations at the site of injury, reduced concentrations of oxidative stress marker (MDA), autophagy improvement (via increasing the expression of LC3-II), and p38 MAPK expression reduction in the superficial dorsal horns (limiting the sensation of neuropathic pain). …”
Get full text

Comparison of Seismic Site Factor Models Based on Equivalent Linear and Nonlinear Analyses and Correction Factors for Updating Equivalent Linear Results for Charleston, South Carol... by Nadarajah Ravichandran, Md. Ariful H. Bhuiyan, Vishnu Saketh Jella, Ashish Bahuguna, Jatheesan Sundararajan

“…In practice, site-specific one-dimensional (1D) seismic site response analyses are conducted to compute surface acceleration time histories considering shear wave velocity profile, modulus reduction, damping, and site-specific ground motions. …”
Get full text

Dynamic response modeling of mine water flooding following grouting and rehabilitating of coalbed water-conducting channels by Xin Li, Xiaofeng Xiong, Ge Chen, Zhimin Xu, Weixiao Chen, Yajun Sun

“…These performances significantly surpassedthe predicted 80% reduction in mine water flooding volume. …”
Get full text

Multi-Timescale Fault Interactions and Earthquakes: A Review by Mian Liu

“…Earthquake models are based on elastic rebound, which predicts cyclic stress accumulation and release on fault planes. …”
Get full text

The Effects of Emotional States and World Assumptions on Moral Disengagement in Adolescents from Combat Zones by Alexandra G. Dolgikh, Olga V. Almazova, Sergei V. Molchanov, Ludmila A. Shaigerova

“…Depression levels (directly) and beliefs in the benevolence and controllability of the world (inversely) predicted moral disengagement.…”
Get full text

Biaxial Tensile Mechanical Properties of HTPB Solid Propellant by Li Jin, Qinzhi Fang, Xingwei Yan, Qinwei Hu

“…The Mises equivalent stress and strain could be used to describe the biaxial tension stress and strain state, and the exponential constitutive model obtained in the study could be used to predict the stress vs. strain curve under different test conditions.…”
Get full text