Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks by Chengtan Wang, Yuying Yang, Mengsi Xu, Fuxiu Mao, Peng Yang, Shan Yuan, Rui Gao, Shangquan Gan

“…In total, 15 key potential circRNAs were predicted to be involved in the posttranscriptional regulation of a series of downstream target genes, which are widely implicated in poststroke processes, such as oxidative stress, apoptosis, inflammatory response, and nerve regeneration, through the competing endogenous RNA mechanism. …”
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Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure by E. V. Kashina, D. Y. Oshchepkov, E. V. Antontseva, M. Y. Shamanina, D. P. Furman, V. A. Mordvinov

“…Putative DREs were predicted using the SITECON software tool in the regulatory regions of the genes encoding transcription factors REL, RELA and IRF1 expressed in macrophages. …”
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In Silico Identification of Potential Inhibitors of the SARS-CoV-2 Nucleocapsid Through Molecular Docking-Based Drug Repurposing by Rukhsar Afreen, Saleem Iqbal, Ab Rauf Shah, Heena Afreen, Lata Vodwal, Mohd. Shkir

“…Silmitasertib, nintedanib, ternatin, luteolin, and fedratinib were found to interact with RNA binding sites and to form a predicted protein interface with high binding energy. …”
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Multifactorial, biomarker-based model for assessing the state of patients with schizophrenia by E. G. Cheremnykh, O. K. Savushkina, T. A. Prokhorova, S. A. Zozulya, I. N. Otman, A. N. Pozdnyakova, N. S. Karpova, Yu. E. Shilov, T. P. Klyushnik

“…The model was evaluated using the Pearson’s test (χ2(11) = 57.6, p = 0.001) and calculation of correct predictions (91 and 80%) for samples of patients and healthy people, respectively.Conclusion. …”
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Cholera-Related Hypochondriasis and Sleep Effort Among Lebanese General Population by Atifa Nazih Kamaleddine, Sondos Mohamad Naous, Sana Ahmad Tantawi, Lama Ali Alhajj, Nafez Nazih Kamaleddine, Sung Woo Joo, Seockhoon Chung

“…Regression analysis indicated that the OCS was predicted by CRBS (β=0.37, p<0.001) and SAVE-6 (β=0.30, p<0.001). …”
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Limits on inferring an effective lithospheric rheology from geodetic observations of the earthquake cycle by Rishav Mallick, Mark Simons

“…Abstract The relationship between stress and deformation of the solid Earth at various temporal and spatial scales can be described using a variety of constitutive relations. …”
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Two-way coupling between ice flow and channelized subglacial drainage enhances modeled marine-ice-sheet retreat by G. Lu, J. Kingslake

“…<p>Ice-sheet models used to predict sea-level rise often neglect subglacial hydrology. …”
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Mental health of residents of radioactively contaminated territories of the Chelyabinsk region in the late period after the resettlement by E. Yu. Burtovaia

“…At the same time, evacuation itself becomes a serious stressful factor that has a negative impact on a person’s health and mental status. …”
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Machinability and Geometric Evaluation of FFF-Printed PLA-Carbon Fiber Composites in CNC Turning Operations by Sergio Martín-Béjar, Fermín Bañón-García, Carolina Bermudo Gamboa, Lorenzo Sevilla Hurtado

“…The results indicate that feed is the most influential parameter across all performance metrics, with lower values leading to improved dimensional accuracy and surface finish, achieving the most significant reductions of 63% in surface roughness (Sa) and 62% in cylindricity deviation. …”
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Charting the future of Brazil’s electricity: a multicriteria analysis of northeastern power strategies amidst climate challenge by Clécio Barbosa Souza Júnior, Johann Köppel, Maria do Carmo Sobral

“…The article addresses the challenges faced by regions under water stress, such as conflicts over water use, environmental degradation, and water resource scarcity, intensified by climate change. …”
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APPROACHES TO BUILDING OF GLOBAL STRATEGIC DETERRENCE SYSTEM PAST 2021 by V. V. Kabernik

“…This includes a number of bilateral agreements for arms control in certain regions, specifically developed to form a system of treaties aimed for global tensions reduction moving towards a safer world in the 21st century.…”
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From Menopause to Molecular Dysregulation: Proteomic Insights into Obesity-Related Pathways—A Narrative Review by Basant E. Katamesh, Jithinraj Edakkanambeth Varayil, Nina Pillai, Ann Vincent

“…Notably, one study demonstrated that weight loss led to reductions in IL-6, IL-1 receptor antagonist, and CRP, suggesting that obesity-related inflammation may be at least partially reversible. …”
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Enhancement of shape recovery and pseudoelasticity in an Fe-18Mn-5Si-7Cr-5Ni shape memory alloy processed by cold rolling by Hamidreza Koohdar, Mozhdeh Jamshidi-Savadroodbari

“…The effect of cold rolling by 20 % and 40 % reductions in thickness on the shape recovery and pseudoelastic behavior of an Fe-18Mn-5Si-7Cr-5Ni (wt. %) shape memory alloy was investigated. …”
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Exploring the Role of GLP-1 Receptor Agonists in Alzheimer’s Disease: A Review of Preclinical and Clinical Evidence by Lívia C. R. Teixeira, Marcelo R. Luizon, Karina B. Gomes

“…Preclinical studies on GLP-1RAs in AD models, both in vitro and in vivo, have demonstrated promising neuroprotective effects, including reductions in amyloid-beta accumulation, decreased tau hyperphosphorylation, improved synaptic plasticity, and enhanced neuronal survival. …”
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Whole-body inhalation study of nanoparticle-enhanced vegetable oil metalworking fluids in mice for assessing occupational health risks by Muralidhar Vardhanapu, Phaneendra Kiran Chaganti, Aparajita Ghosh, Ashutosh Mahale, Onkar Prakash Kulkarni

“…Sirius Red staining revealed minimal collagen deposition and slight reductions in pulmonary airspace. No substantial evidence of lung injury, pulmonary toxicity, or carcinogenicity was observed. …”
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Comparing the biopsychosocial impact of group singing and yoga activities in older adults living with Parkinson’s disease by Arla Good, Alexander Pachete, Sean Gilmore, Frank A. Russo

“…Abstract Research on group singing has demonstrated numerous benefits to wellbeing including boosts in mood, increases in social bonding, and reductions in stress. These benefits can be achieved by individuals with Parkinson’s disease (PD), a group that is especially at risk for social isolation given the typical decline in mobility and communication that accompanies neuromotor degeneration. …”
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Effectiveness of telenursing in improving self-care and blood pressure control among adults with chronic hypertension: a quasi-experimental study in Türkiye by Dursun Alper Yilmaz, Birhat Yakut

“…Results After the intervention, the intervention group exhibited greater reductions in systolic blood pressure (mean Δ = −8.6 mmHg, p = 0.001), pulse pressure (p = 0.001), and mean arterial pressure (p = 0.003) compared to controls. …”
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Computational Evaluation and Multi-Criteria Optimization of Natural Compound Analogs Targeting SARS-CoV-2 Proteases by Paul Andrei Negru, Andrei-Flavius Radu, Ada Radu, Delia Mirela Tit, Gabriela Bungau

“…CHEMBL1495225 establishes multiple hydrogen bonds with the 3CLpro residues ASP197, ARG131, TYR239, LEU272, and GLY195, along with hydrophobic contacts with LEU287. Gene expression predictions via DIGEP-Pred indicated that the top-ranked compounds could influence biological pathways linked to inflammation and oxidative stress, processes implicated in COVID-19’s pathology. …”
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Relationship between cyberbullying and mental health of teenage victims in Saudi Arabia by Suchithra Koipurathu Rajappan, E Aldukhi Amjad Ali, A Alhamad Fajr Hamad, Zahra Abbas A Al Salman, Sarah Marzouq M Alotaibi, M Alobaid Fatimah Riyadh

“…Conclusions: The overall results demonstrate that there is an urgent need in KSA for custom-guided educational and mental health support for all teenagers at home as well as in educational institutions to better respond to cyberbullying.…”
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Educació i narrativa by Fernando Gil

“…The first, naturally, is that of pedagogy and educators: what form does narrative education take in pedagogy today? …”
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