An Exploratory Study Into the Effects of Regular Cold‐Water Sea Swimming on Daily Indices of Mental Health by Jill Forsten, Mark A. Wetherell

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Antibacterial Evaluation of Tricyclic Antidepressants Against <i>S. aureus</i> and the Possible Pathways of the Mechanism of Action by Vitória Pessoa de Farias Cabral, Daniel Sampaio Rodrigues, Lívia Gurgel do Amaral Valente Sá, Lara Elloyse Almeida Moreira, Cecília Rocha da Silva, João Batista de Andrade Neto, Érica Rayanne Mota da Costa, Thais Lima Ferreira, Leilson Carvalho de Oliveira, Beatriz Oliveira de Souza, Dávylla Rênnia Saldanha Pinheiro, Bruno Coêlho Cavalcanti, Islay Lima Magalhães, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior

“…The mechanism of TCAs, isolated and combined with OXA, was associated with a reduction in cell viability, resulting from their action on the bacterial genetic material and generation of oxidative stress. …”
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Effects of Source Directivity and Nonlinear Soil Behavior During the January, 1 2024 Noto Earthquake (Mw = 7.5) by Pavlenko Ol'ga

“…In this research, based on KiK-net vertical array records (11 sites), models of soil behavior in the near-fault zones of the 2024 Noto earthquake are constructed, i.e. vertical distributions of stresses and strains in soil layers changing with time during strong motion, which showed nonlinear soil response and reduction of shear moduli in the near-fault zones. …”
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Overexpression of the STOX1B isoform of STOX1 triggers preeclampsia-like symptoms through HNF4α-dependent alterations of coagulation cascades in mice by Hélène Collinot, Louise Strubé, Ikram Benouda, Johan Castille, Sandrine Floriot, Nathalie Daniel-Carlier, Bruno Passet, Franck Lager, Isabelle Lagoutte, Gilles Renault, Benjamin Saintpierre, Maryline Favier, Djihane Djeridane, Céline Méhats, Francisco Miralles, Jean-Luc Vilotte, Daniel Vaiman

“…The two isoforms have opposite function on major genes involved in trophoblast syncytialization and oxidative stress management. Placenta-fetal overexpression of STOX1A induces preeclampsia in mice. …”
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Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation by Chiara Sassoli, Federica Pierucci, Alessia Tani, Alessia Frati, Flaminia Chellini, Francesca Matteini, Ambra Vestri, Giulia Anderloni, Daniele Nosi, Sandra Zecchi-Orlandini, Elisabetta Meacci

“…Notably, active S1PR1/MMP-2 signalling is required for F-actin structure assembly (lamellipodia, microspikes, and stress fibers) and, in turn, cell proliferation. Moreover, in experimental conditions resembling the damaged/regenerating tissue microenvironment (hypoxia), S1P/S1PR1 system is also required for HIF-1α expression and vinculin reduction. …”
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Comparative study of LPBF Ta–Ti alloy: microstructural evolution and deformation behavior by Zhenyu Yang, Yuanhong Qiu, Jiangqi Zhu, Zhifeng Huang, Shengbin Dai, Weihu Yang, Min Liu, Gang Wang, Xingchen Yan, Wenhua Huang

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Is frequent handling with reinforcement effective in improving management practices for feedlot heifers? by Vitor R. Pacor, Messy H. A. Pantoja, Douglas H. S. Almeida, Isabela M. D. Batista, Milena S. Consorti, Cihan Çamakçı, Cristiane G. Titto

“… Aim of study: This study aimed to evaluate the effect of frequent handling of feedlot female cattle to decrease animal handling time and stress indicators. Area of study: Brazil, São Paulo State. …”
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Anti-inflammatory therapy for tendinopathy using Il1rn mRNA encapsulated in SM102 lipid nanoparticles by Yuan Zhang, Yuan Zhang, Xu Li, Hao Li, Ruiyang Zhang, Ti Zhang, Talante Juma, Yongfei Zhou, Quanyi Guo, Hui Zhao, Yongping Cao

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Investigation of state anxiety levels of parents admitted to the paediatric emergency department by Ahmet Yeşil, Ahmet Butun

“…Abstract Introduction The psychological well-being of parents during their child’s emergency treatment can significantly influence the overall care experience and outcomes. Parental stress and anxiety may affect their ability to provide accurate information, make informed decisions, and support their child effectively during treatment. …”
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Effect of subsolvus and supersolvus solution treatments on the high temperature creep behavior of TC21 titanium alloy with basket-weave microstructure by L.M. Chen, L.R. Xiao, Y.F. Xu, L.R. Zeng, X.J. Zhao, S. Zhang, C. Liu, Z. Fu

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Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis by Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai

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Aurones as new modulators of hypoxia inducible factor-1 (HIF-1) to prevent cardiac cell death by Léa Di Maria, Brayan Roulier, Morane Beaumet, Romain Haudecoeur, Ahcène Boumendjel, Elise Belaïdi, Basile Pérès

“…However, they exhibited divergent effects on HIF-1α expression: 2′- and 3′-hydroxyaurones led to a reduction, whereas 4′-hydroxyaurone caused an increase. …”
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Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus by Qiaolin Wang, Yutong Wu, Lianlian Ouyang, Xiaoli Min, Meiling Zheng, Lingyu Gao, Xiaoyun Chen, Zhi Hu, Shuang Yang, Wenjuan Jiang, Sujie Jia, Qianjin Lu, Ming Zhao

“…Results We observed a significant reduction in CD8αα + IELs, accompanied by a marked increase in CD8αβ + IELs in Lpr mice. …”
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Unveiling the Cardioprotective Potential of Hydroxytyrosol: Insights from an Acute Myocardial Infarction Model by Alejandra Bermúdez-Oria, Eugenia Godoy, Virginia Pérez, Camila Musci Ferrari, Martin Donato, Juan Fernández-Bolaños, Tamara Zaobornyj, Verónica D’Annunzio

“…The results revealed a remarkable 57% reduction in infarct size in HT-treated mice compared to untreated controls. …”
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Fabrication and performance of a novel polymer composite waterproof adhesive layer with enhanced hydrophobicity for concrete bridge decks by Bonan Ma, Fei Wang, Jiaqi Li, Chaodong Yang, Wentao Jia, Kaisheng Luo, Enhui Yang, Yanjun Qiu

“…Even after prolonged water immersion, the reduction in bonding strength was minimal (less than 5 %). …”
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Predictors of burnout among Belgrade veterinary students: A cross-sectional study. by Jelena Ilić Živojinović, Dušan Backović, Goran Belojević, Olivera Valčić, Ivan Soldatović, Janko Janković

“…<h4>Methods</h4>Maslach Burnout Inventory (MBI) and anonymous structured questionnaire addressed to personal data, health habits and stressful influence of educational process were applied among 496 respondents from a total of 1113 students from all grades in spring semester 2014 (response rate 44.6%).…”
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The blueprint for survival: the blue dasher dragonfly as a model for urban adaptation by Ethan R. Tolman, Ellie Gamett, Christopher D. Beatty, Aaron Goodman, Brittney Hahn, Christian Benischek, Gracie Castillo, Ethan Derderian, Santiago Fernandez-Juarez, Ben Gallafent, James Jenson, Dick Jordan, Magnolia Schneider, Roberto Salazar, Towako Tamano, Maleah Wei, Jacob Idec, Rob Guralnick, Jessica L. Ware, Manpreet K. Kohli

“…Using one of the most robust locality datasets for any species to date, we also generate habitat suitability predictions which show that P. longipennis has spread with urbanization, suggesting humans have created suitable habitat for this species. …”
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Artificial Intelligence for Smart Cities: A Comprehensive Review Across Six Pillars and Global Case Studies by Joel John, Rayappa David Amar Raj, Maryam Karimi, Rouzbeh Nazari, Rama Muni Reddy Yanamala, Archana Pallakonda

“…Key AI applications ranging from predictive analytics in e-governance to machine learning models in renewable energy management and autonomous mobility systems are synthesized domain-wise throughout this study. …”
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The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease by Jiayuan Murphy, Tran Ngoc Van Le, Julia Fedorova, Yi Yang, Meredith Krause-Hauch, Kayla Davitt, Linda Ines Zoungrana, Mohammad Kasim Fatmi, Edward J. Lesnefsky, Edward J. Lesnefsky, Ji Li, Di Ren

“…This study aims to characterize cellular defects resulting in decreased cardiac function in AD-model. 5XFAD mice, a strain expressing five mutations in human APP and PS1 that shows robust Aβ production with visible plaques at 2 months and were used in this study as a model of AD. 5XFAD mice and wild-type (WT) counterparts were subjected to echocardiography at 2-, 4-, and 6-month, and 5XFAD had a significant reduction in cardiac fractional shortening and ejection fraction compared to WT. …”
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Decoding metabolic trade-offs in Halomonas elongata: Chemostat-based flux remodeling for industrial ectoine biosynthesis by Junxiong Yu, Hao Liu, Yudi Wang, Runlin Ju, Yue Zhang, Ali Moshin, Yingping Zhuang, Meijin Guo, Zejian Wang

“…These findings establish H. elongata as a paradigm of dynamic flux rewiring, where carbon economy is strategically reallocated between stress-protective solute biosynthesis and energy homeostasis. …”
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