Suggested Topics within your search.
Suggested Topics within your search.
-
5061
Comparative study: trimetazidine versus olanzapine on cognitive dysfunction and behavioral changes in ketamine-induced psychosis model in mice
Published 2025-04-01“…Olanzapine induced less improvement in cognitive function with a reduction in PGC1α and muscle grip.…”
Get full text
Article -
5062
Frictional Experiments on Granitic Faults: New Insights into Continental Earthquakes and Micromechanical Mechanisms
Published 2025-06-01“…In particular, microstructural observations reveal that grain size reduction, pressure solution creep, and fluid-assisted chemical processes are key mechanisms governing transitions between velocity-weakening and velocity-strengthening regimes. …”
Get full text
Article -
5063
Age-Related Alterations in the Expression of Genes and Synaptic Plasticity Associated with Nitric Oxide Signaling in the Mouse Dorsal Striatum
Published 2015-01-01“…Corticostriatal NO-dependent LTD induced by pharmacological activation of group I metabotropic glutamate receptors underwent significant reduction with aging and could be restored by inhibition of cGMP hydrolysis indicating that its age-related deficit is caused by an altered NO-cGMP signaling cascade. …”
Get full text
Article -
5064
Physical modeling of glacier contact with bedrock (experiment)
Published 2015-04-01“…The natural glacier spectra revealed periodic reduction of AE signals frequency in the middle range of frequencies. …”
Get full text
Article -
5065
Effects of Integrating Music Therapy into Family Support System on Adolescent Depression
Published 2025-03-01“…The ASLEC score showed a greater reduction in aspects such as interpersonal relationships, academic stress, punishment, and loss (P < 0.05). …”
Get full text
Article -
5066
The potential of spirulina platensis to substitute antibiotics in broiler chickens diets: influences on growth performance, serum biochemical profiles, meat quality, and gut microb...
Published 2025-07-01“…Liver enzymes remained stable, with a 13-45% reduction in kidney markers based on the SPE concentration. …”
Get full text
Article -
5067
p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies.
Published 2016-01-01“…Upon recovery from DDC intoxication on a standard diet, there was an enhanced reduction of p62-deficient MDBs, which was accompanied by a pronounced decrease in ubiquitinated proteins. …”
Get full text
Article -
5068
The Cellular and Mitochondrial Consequences of Mevalonate Pathway Inhibition by Nitrogen-Containing Bisphosphonates: A Narrative Review
Published 2025-07-01“…As we have shown in endothelial cells, by inhibiting the mevalonate pathway, N-BPs may lead to a reduction in key components of the mitochondrial respiratory chain, such as coenzyme Q (CoQ) and <i>a</i>-heme. …”
Get full text
Article -
5069
The putative protein methyltransferase LAE1 of Trichoderma atroviride is a key regulator of asexual development and mycoparasitism.
Published 2013-01-01“…Deletion of lae1 also increased the sensitivity of T. atroviride to oxidative stress, abolished its ability to defend against other fungi and led to a loss of mycoparasitic behaviour, whereas the OElae1 strains displayed enhanced mycoparasitic vigor. …”
Get full text
Article -
5070
Evaluation of Slope Stability and Landslide Prevention in a Closed Open-Pit Mine Used for Water Storage
Published 2025-08-01“…This study shows that during the impoundment process, the slope stability has a nonlinear decreasing trend due to the decrease in effective stress caused by the increase in pore water pressure. …”
Get full text
Article -
5071
Behavior of arch composite beam: Experimental and numerical investigation
Published 2025-06-01“…Results demonstrated that external prestressing increased the ultimate moment capacity by 80 %, reduced mid-span deflection by 60 %, and significantly redistributed internal stresses, promoting a favorable arching effect. Furthermore, reducing the number of shear connectors by 50 % led to a 28 % reduction in stiffness and a 20 % increase in ductility, with negligible impact on ultimate load. …”
Get full text
Article -
5072
Ferroptosis: New Strategies for Clinical Treatment of Rheumatoid Arthritis
Published 2025-05-01“…These include its roles in regulating oxidative stress and lipid peroxidation, inhibiting the abnormal proliferation of synovial fibroblasts (FLSs), preventing cartilage erosion, restoring immune homeostasis and inflammatory responses, and other aspects. …”
Get full text
Article -
5073
P55 | ENDOTHELIAL THYMIDINE PHOSPHORYLASE DEFICIENCY TRIGGERS MORPHO-FUNCTIONAL DEGE-NERATION OF ENTERIC NEURONS AND REDUCES INTESTINAL STEM CELL PROLIFERATION
Published 2025-08-01“…Remarkably, in a cohort of idiopathic CIPO patients, we revealed through histochemical analysis a scenario similar to MINGIE, with a 50% reduction in jejunal TP correlating with vascular alterations and partial denervation. …”
Get full text
Article -
5074
Design of monoblock crossing for heavy operating conditions
Published 2023-07-01“…The lowest equivalent stresses are found in one of the monoblock crossing designs with two longitudinal stiffening ribs presented in the article. …”
Get full text
Article -
5075
Influence of the Number of Parallel Joints on the Dynamic Mechanical Properties of Rock-Like Features
Published 2022-01-01“…Thus, as the number of joints increases, the static strength decreases, and the degree of reduction is positively related to the number of joints. …”
Get full text
Article -
5076
Investigating the effects of microwave plasma on bacterial cell structures, viability, and membrane integrity
Published 2025-05-01“…This study investigates the antibacterial effect of 2.45 GHz non-thermal microwave (MW) plasma on Staphylococcus aureus (S. aureus) and Salmonella abony (S. abony) suspended in phosphate-buffered saline (PBS). A 6-log reduction in both bacterial strains was achieved within 300 s of plasma exposure. …”
Get full text
Article -
5077
Mixed chronic scrotal pain secondary to piriformis scarring treated with PRF: case report
Published 2025-08-01“…The therapeutic strategy synergistically addressed all three cascades of mechanisms via C-fiber modulation, reduction of pro-inflammatory cytokines, and reversal of neuroplasticity. …”
Get full text
Article -
5078
Topological optimization design of the front coupling rod of prosthetic knee joint based on Inspire
Published 2025-06-01“…This optimization process is aimed at achieving mass reduction of the prosthetic motion mechanism while improving its structural performance. …”
Get full text
Article -
5079
Can Yoga Help to Manage the Symptoms of Thyroid Diseases?
Published 2025-01-01“…Studies revealed a trend toward balance in thyroid hormone, reduction in psychological symptoms such as stress, anxiety, and depression, and improvement in the quality of life of thyroid patients through Yoga. …”
Get full text
Article -
5080
Impact of column axial load level of the seismic behavior of concrete-filled UHPC tubular column-to-footing connections reinforced with different spiral stirrup spacing
Published 2025-06-01“…In addition, deformations were also improved along with reduced drift ratios due to the role of UHPC in bridging the resulting cracks. Finally, the reduction in the spiral stirrup spacing enhances the overall cyclic performance of the structural system.…”
Get full text
Article