Effect of Celery (Apium graveolens L.) Microgreens on Drosophila melanogaster by Mohamad Agus Salim, Muhammad Subandi, Yeni Yuniarti

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Towards climate-resilient social housing: thermal comfort assessment and renovation guidelines in the Brazilian mixed-dry climate zone by Karen Carrer Ruman de Bortoli, Simone Barbosa Villa

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Differentiated approach to the treatment of musculoskeletal pain: higher doses of analgesics provide a better effect. A brief narrative review by A. E. Karateev, A. M. Lila

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Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer by Florian Uhlitz, Philip Bischoff, Stefan Peidli, Anja Sieber, Alexandra Trinks, Mareen Lüthen, Benedikt Obermayer, Eric Blanc, Yana Ruchiy, Thomas Sell, Soulafa Mamlouk, Roberto Arsie, Tzu‐Ting Wei, Kathleen Klotz‐Noack, Roland F Schwarz, Birgit Sawitzki, Carsten Kamphues, Dieter Beule, Markus Landthaler, Christine Sers, David Horst, Nils Blüthgen, Markus Morkel

“…Experimental targeting of EGFR‐BRAF‐MEK in cancer organoids affected signaling and gene expression contingent on predictive KRAS/BRAF mutations and induced cell plasticity overriding default developmental trajectories. …”
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Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension by Era Gorica, Jacopo Spezzini, Iliana Papadopoulou, Marialucia Telesca, Valeria Masciovecchio, Shafeeq A. Moahmmed, Alessandro Mengozzi, Hung-Wei Cheng, Natalia Atzemian, Ludovica Di Venanzio, Alessia Mongelli, Omer Dzemali, Vincenzo Calderone, Francesco Paneni, Christian M. Matter, Burkhard Ludewig, Frank Ruschitzka, Sarah Costantino

“…In vitro experiments were performed to study the mechanisms underlying metabolic stress-induced macrophage dysfunction using palmitic acid (PA), co-culture experiments were used to investigate the crosstalk between macrophages and endothelial cells. …”
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Calidad de sueño, salud mental y actividad física en estudiantes universitarios de la Amazonía peruana (Sleep quality, mental health and physical activity in university students fr... by Jimmy Nelson Paricahua-Peralta, Edwin Gustavo Estrada-Araoz, Ronald Socrates Poma-Mollocondo, Libertad Velasquez-Giersch, Alhi Jordan Herrera-Osorio, George Jhon Cruz-Visa, Manuel Felipe Guevara-Duarez, Osbel Mora-Estrada, Elizabeth Orfelia Cruz-Laricano

“…In the context of higher education, sleep quality, mental health, and physical activity are key variables for understanding the overall well-being of students. …”
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Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures by Nicholas A Graham, Aspram Minasyan, Anastasia Lomova, Ashley Cass, Nikolas G Balanis, Michael Friedman, Shawna Chan, Sophie Zhao, Adrian Delgado, James Go, Lillie Beck, Christian Hurtz, Carina Ng, Rong Qiao, Johanna ten Hoeve, Nicolaos Palaskas, Hong Wu, Markus Müschen, Asha S Multani, Elisa Port, Steven M Larson, Nikolaus Schultz, Daniel Braas, Heather R Christofk, Ingo K Mellinghoff, Thomas G Graeber

“…Using a pan‐cancer analysis of CNA data from patient tumors and experimental systems, here we show that principal component analysis‐defined CNA signatures are predictive of glycolytic phenotypes, including 18F‐fluorodeoxy‐glucose (FDG) avidity of patient tumors, and increased proliferation. …”
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Study on Macroscopic and Microscopic Mechanical Behavior of Magnetorheological Elastomers by Representative Volume Element Approach by Shulei Sun, Xiongqi Peng, Zaoyang Guo

“…Then by introducing the Maxwell stress tensor, a two-dimensional plane stress RVE for the MRE is developed in COMSOL Multiphysics to study its response under a magnetic field. …”
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The impact of ride hailing on parking (and vice versa) by Alejandro Henao, Wesley E. Marshall

“…This includes building a classification tree-based model to predict the replaced driving trips as a function of car ownership, destination land type, parking stress, and demographics. …”
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Cuproptosis: a novel therapeutic mechanism in lung cancer by Cheng Luo, Xinhui Wu, Shipeng Zhang, Junwen Tan, Yuzhi Huo, Xinyue Zhang, Bo Ning, Yuanhang Ye, Fei Wang

“…These elements are vital for evaluating clinical interventions for lung cancer patients, predicting risks, and recognizing drug resistance. Moreover, we identified that pharmaceuticals facilitating copper ion transport (elesclomol and disulfiram), copper-chelating agents (DPEN, ATTM, and TETA), and nanoparticles engineered to transport copper are capable of effectively adjusting copper ion concentrations in lung cancer cells, subsequently inducing cuproptosis as a prospective treatment strategy for lung cancer. …”
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Analysis and Case Study of Internal Forces in Nut Column Transmission System of Shiplifts by WANG Di, LIAO Le-kang, JIN Liao

“…Moreover, except for axial force, all other internal forces in the adjustment beam exceeded those in the nut column, providing critical insights for structural optimization. (4) Stress comparison: Calculated stress values, though slightly exceeding experimental results, remained within allowable stress limits, demonstrating the rationality of the current design. …”
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The influence of entanglements of macromolecules on the mechanical and thermal properties of polylactide composites with carbon nanotubes by Hoorieh Barangizi, Justyna Krajenta, Andrzej Pawlak

“…The influence of the reduction of macromolecular entanglements on the thermal and mechanical properties of polylactide composites containing 0.1–1.0 wt% of carbon nanotubes was investigated. …”
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Effect of legacy and emerging pollutants on genome-wide methylation patterns in black hake (Merluccius polli) natural populations by Carmen Blanco-Fernandez, María Bobes-Villa, Ainhoa López, Daniel Menéndez, Kathryn R. Elmer, Eva Garcia-Vazquez, Gonzalo Machado-Schiaffino

“…Elevated Pb was significantly associated with a reduction in hake condition factor. Differentially methylated loci were associated with diverse pathways associated to responses for all pollutants (e.g. immune response, gene expression regulation), pointing to signs of stress within the population. …”
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SOCIOLOGICAL STUDY OF THE HEALTH STATUS OF DENTISTS OF THE DENTAL PROFILE by S.V. Melnyk, L.F. Horzov, V.S. Melnyk

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Effects and mechanisms of warming on the relationship between soil organic matter degradation and methylmercury production in Hg-contaminated soil by Siqi Zhang, Sihua Zhu, Shanyi Tian, Jianxu Wang, Yongguang Yin, Jitao Lv, Yongmin Wang, Tao Jiang, Zhenwu Tang, Dingyong Wang

“…Future research should incorporate contaminated soils into global carbon models to improve SOM turnover predictions in terrestrial systems.…”
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“Weibing” in traditional Chinese medicine—biological basis and mathematical representation of disease-susceptible state by Wanyang Sun, Rong Wang, Shuhua Ouyang, Wanli Liang, Junwei Duan, Wenyong Gong, Lianting Hu, Xiujuan Chen, Yifang Li, Hiroshi Kurihara, Xinsheng Yao, Hao Gao, Rongrong He

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Effects of supercritical CO2, water, and supercritical CO2-based water on the mechanical properties and fracturability of shale by Qiao Lyu, Jinghong Deng, Yijun Shen, Yonggang Ding, Yushuai Shi, Gan Feng, Jingqiang Tan

“…The key findings are as follows: (1) Uniaxial compressive strength (UCS) of shale decreased by 10.72%, 11.95%, and 23.67% at 15 MPa, and by 42.40%, 46.84%, and 51.65% at 45 MPa after immersion in ScCO2, DW, and ScCO2+DW, respectively, with the most pronounced effect observed in ScCO2+DW; (2) Microstructural analysis revealed that while ScCO2 and DW do not significantly alter the microstructure, immersion in ScCO2+DW results in a more complex surface morphology; (3) Acoustic emission (AE) analysis indicates a reduction in stress for crack damage, with a decreased fractal dimension of AE signals in different fluids. …”
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Transformation of Ukrainian students’ attitudes toward wheelchair users amid the Russian-Ukrainian war by Andriej Szpakow, Krystyna Kowalczuk, Yuliia Antonova-Rafi, Igor Khudetskyy, Oryna Detsyk, Olga Fedortsiv, Oksana Hdyrya, Andriy Bazylevych, Liudmila Vilchynskaya

“…The increase in positive emotions, reduction in tension, stress, helplessness, and shame indicate an improvement in mental well-being. …”
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Mechanisms of Cisplatin-Induced Acute Kidney Injury: The Role of NRF2 in Mitochondrial Dysfunction and Metabolic Reprogramming by Jihan Liu, Yiming Wang, Panshuang Qiao, Yi Ying, Simei Lin, Feng Lu, Cai Gao, Min Li, Baoxue Yang, Hong Zhou

“…Furthermore, we activated NRF2 using dimethyl fumarate (DMF), observing a reduction in kidney damage and lipid deposition in mice. …”
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Reprotoxicity of zinc oxide nanoparticles synthesized with Crataegus monogyna leaves extract: testis and sperm function by F. REMITA, A. TALBI, C. ABDENNOUR, K. KHELILI, Y. BEDOUH, F. HAMOUD, F. DUMAN, Z. BOUSLAMA, R. ROUABHI, M. R. DJEBAR

“…Compared to the control, ZNP1 has a significant reduction of testicular and epididymis weights, sperm concentration, live sperm, motility, VCL, VSL, VAP, LIN, and BCF, with a significant increase of MDA and a significant decrease of GSH levels. …”
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