CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa by Yu Zhang, Tingting Zhang, Xue Xiao, Yejun Wang, Adam Kawalek, Jinzhao Ou, Anmin Ren, Wenhao Sun, Vincent de Bakker, Yujie Liu, Yuelong Li, Liang Yang, Liang Ye, Ning Jia, Jan-Willem Veening, Xue Liu

“…We classify the essential genes by response time and growth reduction, pinpointing the most vulnerable therapeutic targets in this species. …”
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Hesperidin-β-Cyclodextrin inclusion complexes: A novel approach for preventing and treating acute lung injury caused by seawater drowning by Jingjing Hou, Mengdi Zhang, Zheyi Han, Wanmei Wang, Haiying Qiu, Jingwei Yuan, Fang An, Yan Wu

“…The administration of Hep-β-CD via the pulmonary route has been found to be highly effective in preventing seawater drowning-induced ALI in mice, achieved through modulation of key inflammatory mediators and a reduction in oxidative stress. The study demonstrated that Hep-β-CD administration significantly decreased the levels of pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-α) and Interleukin-6 (IL-6), which are known to contribute to the pathogenesis of ALI. …”
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<i>N</i>-Acetylcysteine Treatment Restores the Protective Effect of Heart Ischemic Postconditioning in a Murine Model in the Early Stages of Atherosclerosis by Tamara Zaobornyj, Virginia Perez, Georgina Ossani, Tamara Mazo, Eugenia Godoy, Jorge Godoy, Yohana Yanaje, Camila Musci-Ferrari, Mario Contin, Valeria Tripodi, Magali Barchuk, Gabriela Berg, Ricardo J. Gelpi, Martin Donato, Veronica D’Annunzio

“…The analysis indicates that animals subjected to I/R and IP protocols in conjunction with NAC show a tendency to reach basal values, thus suggesting a potential for the reduction in ROS. <b>Conclusions:</b> NAC treatment mitigates oxidative stress and restores the cardioprotective effect of ischemic postconditioning in a model of early-stage atherosclerosis. …”
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The Effectiveness of Wisdom Training on Academic Emotions, Academic Motivation and Subjective Vitality in Students by Masoomeh Azizi, Abolghasem Yaghoobi

“…Mindfulness education encourages the constructive use of emotions. …”
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Development and engineering application validation of alkali-activated full-component shield tunnel spoil regenerated solid-waste grouting material by Zhiran Yang, Yu Zhou, Li Wang, Shizhuo Zou, Jinfei Chai, Yufei Fang, Shichao Jiang, Hui Ma

“…This low-cement-content approach combined with solid waste recycling technology provides a practical solution for green construction, carbon reduction, and resource recycling in underground engineering.…”
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Phase-Resolved Functional Lung MRI Evaluation of Dynamic Hyperinflation Induced by Metronome-Paced Tachypnea in Patients with Chronic Obstructive Pulmonary Disease by R. A. Müller, F. Klimeš, A. Voskrebenzev, L. Behrendt, T. F. Kaireit, M. Wernz, M. Zubke, A. L. Kern, M. R. Prince, W. Shen, C. B. Cooper, R. G. Barr, J. M. Hohlfeld, J. Vogel-Claussen

“…MPT in combination with phase-resolved functional lung (PREFUL) MRI can be used to assess stress-driven ventilation dynamics globally and regionally. …”
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Combining mindfulness intervention and open-label placebo treatment for chronic pain: a protocol for a feasibility study by Chung Jung Mun, Estrella Contreras, Yushu Xiao, Ryan Eckert, Alexandra Harting, Sathvika Damera, Iosef Perez, Hemant K. Pandey, Aram S. Mardian, Frank LoVecchio, Luana Colloca, Kelly E. Dunn, Michael Todd, Roger B. Fillingim, Mary C. Davis

“…Abstract Background Mindfulness-based interventions, such as mindfulness-based stress reduction (MBSR), are efficacious mind–body treatments for chronic pain, though their modest effect sizes suggest room for improvement. …”
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Mental health problems among female sex workers in low- and middle-income countries: A systematic review and meta-analysis. by Tara S Beattie, Boryana Smilenova, Shari Krishnaratne, April Mazzuca

“…Key risk factors include poverty, low education, violence, alcohol and drug use, human immunodeficiency virus (HIV), and stigma and discrimination. …”
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Changes and Risk Factors of Skeletal Muscle Mass and Strength in Patients with Type 2 Diabetes over 60 Years Old: A Cross-Sectional Study from China by Liming Hou, Yan Liu, Xing Li, Cong Huo, Xin Jia, Jie Yang, Yunzhen Lei, Rong Xu, Chao Sun, Xiaoming Wang

“…Muscle mass and strength of patients with higher education level were significantly higher than those with lower education level (P<0.05), in male patients, muscle mass and muscle strength were significantly lower in smokers (P<0.01), and muscle mass was lower in chronic drinkers (P<0.05). …”
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Dying of starvation if not from bombs: assessing measurement properties of the Food Insecurity Experiences Scale (FIES) in Gaza’s civilian population experiencing the world’s worst... by Feten Fekih-Romdhane, Kamel Jebreen, Tasnim Swaitti, Mohammed Jebreen, Eqbal Radwan, Wafa Kammoun-Rebai, Inad Nawajah, Omar Shamsti, Sahar Obeid, Souheil Hallit

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Sociodemographic factors associated with alcohol consumption among men in Gabon: insights from the Gabon demographic and health survey of 2019–2021 by Gosa Mankelkl, Beletu Kinfe

“…The primary driver of alcohol consumption is likely its capacity to elevate mood and alleviate stress. More than 200 medical conditions, including liver diseases, traffic accidents, violence, cancer, heart disease, suicide, tuberculosis, and HIV/AIDS, have been causally associated with alcohol consumption. …”
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Network of cognitive, emotional, and pain perception factors linked to non-suicidal self-injury in Chinese adolescents by Wei Luo, Jingbo Gong, Han-yu Zhou, Juanjuan Guo, Jieyu Xiao, Chao Yan, Yuqi Chen

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Experiences of healthcare professionals providing palliative care in home settings - a scoping review by Luke Tan, Sonia Sheri, Yun Yao Goh, Raeanne Fong, Ranitha Govindasamy, Yun Ting Ong, Nur Amira Binte Abdul Hamid, Tessa Li Xiang Low, Lalit Kumar Radha Krishna

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Acoustic output levels and ultrasound output display standard by P. A. LEWIN, A. NOWICKI

“…Three different tissue models, namely, homogeneous and layered, and bone/tissue interface are presented in detail and the influence of each of the models on the potential temperature increase prediction is stressed. The importance of implementation of ALARA (As Low As Reasonably Achievable) principle is also noted out.…”
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Gill transcriptome profiling reveals adaptation to brackish water in a selectively bred hybrid tilapia (Oreochromis niloticus x O. aureus) strain by Xiaofei Yu, July B. Ariñez, Priadi Setyawan, Zhitian Wu, Muhammad Hunaina Fariduddin Aththar, Mark Camara, Yang Fang, Martien A.M. Groenen, Hans Komen, John W.M. Bastiaansen, Hendrik-Jan Megens

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Natural variation of AcEGY3 mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance by Chengcheng Ling, Jun Yang, Jiale Xu, Wei Tang, Yunyan Liu, Yingzhen Wang, Pengwei Li, Yan He, Zhiyin Ouyang, Shuqi Chen, Fei Xing, Xinxin Wang, Pu Liu, Yajing Liu, Runze Wang, Xiaofen Liu, Xueren Yin, Heqiang Huo, Dawei Li, Jan Smalle, Yongsheng Liu, Songhu Wang

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Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals by I. N. Tyurenkov, D. A. Bakulin, A. V. Smirnov, M. R. Ekova, A. I. Bisinbekova, G. L. Snigur, Yu. I. Velikorodnaya, E. I. Morkovin, D. V. Verkholyak, O. S. Vasilyeva

“…These effects may be due to higher levels of the Klotho proteins, Nrf2 and BDNF, as well as lower levels of NF-κB, which may underlie the suppression of the oxidative stress, the reduction of MDA and inflammation (TNF-α).Conclusion. …”
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Experimental study on the sensitive neighboring area range of red sandstone under rheological disturbance effect by Bo WANG, Yongzheng REN, Zhiyin TIAN, Shiji MA, Xiangyu GAO, Hongxu SUN, Jun WANG, Wanpeng HUANG

“…This study, under different confining pressure conditions, subdivides the axial stress levels of red sandstone rheology, selecting stages of cumulative residual deformation development under rock rheological disturbance effects (attenuation stage, near constant speed stage, and acceleration stage). …”
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Exploring the molecular mechanism of OsROS1a in regulating resistance to bacterial leaf streak through transcriptome and DNA methylation profiling in rice (Oryza sativa L.) by Xiaofang Xie, Xuansong Yang, Libin Lu, Tong Li, Mingyue Qin, Huazhong Guan, Yan Zheng, Tao Lan, Weiren Wu

“…The DEGs in cluster 1 were enriched in the biological process related to defense response, response to stress, oxidation-reduction, etc. Integration of the methylome and transcriptome data revealed 112 overlapping differentially methylated and expressed genes (DMEGs). …”
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Effect of levodopa and clioquinol on antioxidant capacity in Parkinson’s disease rhesus monkeys by LI Like, SHI Liangqin, LIU Heng, LUO Qihui, HUANG Chao, LIU Wentao, CHEN Xiaolin, CHEN Zhengli

“…In addition, vocalization reduction was the first symptom, but it was indistinct; furthermore, we found that the monkeys became increasingly bradykinetic, and finally presented with tremors, which were stronger and earlier at the arms than at the legs. …”
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