Studies on nanoprotein vaccine alleviating symptoms of mice allergic to rFel d 1 by Yanqi Mai, Xiaozheng Sun, Xiaoxuan Liu, Huricha Chen, Xinglan Liang, Ying Huang, Xiaojuan Wu, Shuangshuang Wei, Shuangshuang Wei, Dayong Wang, Dayong Wang, Yechun Pei, Yechun Pei

“…We utilized a mouse model sensitized with purified rFel d 1 and then immunized them subcutaneously with LDH nanoparticles loaded with PADRE-rFel d 1.ResultsOur results indicated that this nanoparticle vaccine effectively restored the balance of Th1/Th2 and Th17/ Treg cells, which led to a reduction in inflammatory cell infiltration, mitigated local and systemic stress responses induced by rFel d 1, decreased airway hyperresponsiveness, and lowered serum IgE levels.DiscussionConsequently, the LDH loaded with PADRE-rFel d 1 vaccine shows promise as an effective treatment for cat allergies.…”
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Calculation Model of Multi-roll Straightening Process Based on Bilinear Hardening and Power Hardening by ZHU Xiaoyu, CHENG Zixing, WANG Xiaogang, HAN Peisheng

“…The results show that with increasing reduction, the error between hardened and ideal models increases. …”
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Relevance of Biofilms in the Pathogenesis of Shiga-Toxin-Producing Escherichia coli Infection by Natalia Angel Villegas, José Baronetti, Inés Albesa, Rosana Polifroni, Alberto Parma, Analía Etcheverría, Maria Becerra, Nora Padola, Maria Paraje

“…The reactive oxygen species (ROSs) were detected by the reduction of nitro blue tetrazolium and reactive nitrogen intermediates (RNI) determined by the Griess assay. …”
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Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation by Marco Contoli, Giulia Gnesini, Giacomo Forini, Brunilda Marku, Alessia Pauletti, Anna Padovani, Paolo Casolari, Liliana Taurino, Andrea Ferraro, Milva Chicca, Adalberto Ciaccia, Alberto Papi, Silvano Pinamonti

“…Inhalation of reducing agents resulted in a significant reduction of O2- production in exhaled breath condensate of COPD patients at the end of the inhalatory treatment and at followup compared to baseline. …”
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The Effectiveness of Wisdom Training on Academic Emotions, Academic Motivation and Subjective Vitality in Students by Masoomeh Azizi, Abolghasem Yaghoobi

“…Mindfulness education encourages the constructive use of emotions. …”
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Advancing Understanding of High-Temperature Micro-Electro-Mechanical System Failures with New Simulation-Assisted Approach by Weronika Lidia Sadurska, Matthias Imboden, Jürgen Burger, Alex Jean Dommann

“…This study introduces a simulation-assisted approach to analyze and predict the dominant failure modes, focusing on vacancy fluxes and their driving forces, within high-temperature MEMS structures. …”
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Variables psicológicas y clínicas presentes en pacientes portadores de dolor crónico de espalda by Ahmed José Pomares Avalos, Teresa Rodríguez Rodríguez, José Antonio Pomares Alfonso

“…The study variables were: age, sex, educational level, occupation, origin, characteristics of pain (intensity, frequency, duration, type of treatment used for its relief), anxiety, depression, anger and hostility as personality traits, and anxiety, depression and stress as negative emotional states. …”
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CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa by Yu Zhang, Tingting Zhang, Xue Xiao, Yejun Wang, Adam Kawalek, Jinzhao Ou, Anmin Ren, Wenhao Sun, Vincent de Bakker, Yujie Liu, Yuelong Li, Liang Yang, Liang Ye, Ning Jia, Jan-Willem Veening, Xue Liu

“…We classify the essential genes by response time and growth reduction, pinpointing the most vulnerable therapeutic targets in this species. …”
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Structural, Electronic, Dynamic, and Optical Properties of 2D Monolayer Tungsten Telluride (2H-WTe2) under Small Biaxial Strain Using Density Functional Theory (DFT and DFT + U)... by Mulugeta Woldesenbet, Nebiyu Debelo, Menberu Woldemariam

“…Moreover, the band gap values determined using Hubbard correction (GGA + U) are 1.1089 eV (unstrained), 1.2332 eV (2% biaxial compression), and 0.9945 eV (2% biaxial tensile stress), respectively. The band gap value obtained using Hubbard correction predicts the experimental value more precisely. …”
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Mental health problems among female sex workers in low- and middle-income countries: A systematic review and meta-analysis. by Tara S Beattie, Boryana Smilenova, Shari Krishnaratne, April Mazzuca

“…Key risk factors include poverty, low education, violence, alcohol and drug use, human immunodeficiency virus (HIV), and stigma and discrimination. …”
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Changes and Risk Factors of Skeletal Muscle Mass and Strength in Patients with Type 2 Diabetes over 60 Years Old: A Cross-Sectional Study from China by Liming Hou, Yan Liu, Xing Li, Cong Huo, Xin Jia, Jie Yang, Yunzhen Lei, Rong Xu, Chao Sun, Xiaoming Wang

“…Muscle mass and strength of patients with higher education level were significantly higher than those with lower education level (P<0.05), in male patients, muscle mass and muscle strength were significantly lower in smokers (P<0.01), and muscle mass was lower in chronic drinkers (P<0.05). …”
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Advancing life expectancy in Saudi Arabia: insights from global best practices by Hala Alosaimi, Haitham Alnouri, Ibrahim Alasiri, Saad Almushawah, Mansour Mohammed, Ameera Abdulrahman, Rana A. Alotaibi, Rasha Alfawaz, Abdulaziz Abdulbaqi, Weam Banjar, Tareef Alaama, Mariam M. AlEissa

“…The key indicators analysed included healthcare access, cultural/social awareness, education, nutrition, lifestyle, and socioeconomic factors. …”
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Intramuscular Reactivity of the Modified Graphene Oxides and Their Bio-Reactivity in Aging Muscle by Xiaoting Jian, Jiayin Wang, Jijie Hu, Yangyang Li, Qisen Wang, Han Wang, Jingwen Huang, Yu Ke, Hua Liao

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The regolith-hosted clay REEs leaching effects by mechanical grinding and at low temperature: An analogy on treatment method by Hassan Nasir Mangi, Liqiang Ma, Ru'an Chi, Chenghao Wu, Zhenyue Zhang, Yan DeTian, Lara Sindhu, Khalid Thebo, Umar Ashraf

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Dying of starvation if not from bombs: assessing measurement properties of the Food Insecurity Experiences Scale (FIES) in Gaza’s civilian population experiencing the world’s worst... by Feten Fekih-Romdhane, Kamel Jebreen, Tasnim Swaitti, Mohammed Jebreen, Eqbal Radwan, Wafa Kammoun-Rebai, Inad Nawajah, Omar Shamsti, Sahar Obeid, Souheil Hallit

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Sociodemographic factors associated with alcohol consumption among men in Gabon: insights from the Gabon demographic and health survey of 2019–2021 by Gosa Mankelkl, Beletu Kinfe

“…The primary driver of alcohol consumption is likely its capacity to elevate mood and alleviate stress. More than 200 medical conditions, including liver diseases, traffic accidents, violence, cancer, heart disease, suicide, tuberculosis, and HIV/AIDS, have been causally associated with alcohol consumption. …”
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Network of cognitive, emotional, and pain perception factors linked to non-suicidal self-injury in Chinese adolescents by Wei Luo, Jingbo Gong, Han-yu Zhou, Juanjuan Guo, Jieyu Xiao, Chao Yan, Yuqi Chen

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Experiences of healthcare professionals providing palliative care in home settings - a scoping review by Luke Tan, Sonia Sheri, Yun Yao Goh, Raeanne Fong, Ranitha Govindasamy, Yun Ting Ong, Nur Amira Binte Abdul Hamid, Tessa Li Xiang Low, Lalit Kumar Radha Krishna

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Hesperidin-β-Cyclodextrin inclusion complexes: A novel approach for preventing and treating acute lung injury caused by seawater drowning by Jingjing Hou, Mengdi Zhang, Zheyi Han, Wanmei Wang, Haiying Qiu, Jingwei Yuan, Fang An, Yan Wu

“…The administration of Hep-β-CD via the pulmonary route has been found to be highly effective in preventing seawater drowning-induced ALI in mice, achieved through modulation of key inflammatory mediators and a reduction in oxidative stress. The study demonstrated that Hep-β-CD administration significantly decreased the levels of pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-α) and Interleukin-6 (IL-6), which are known to contribute to the pathogenesis of ALI. …”
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Clinical, Microbiological, and Biochemical Outcomes of Hyaluronic Acid in Non-Surgical Periodontal Therapy: A Systematic Review and Meta-Analysis by Alessia Pardo, Veronica Magnani, Pietro Montagna, Andrea Ala, Gabriele Brancato, Federica Melloni, Giorgio Lombardo, Daniele De Santis

“…Compared with SRP alone, the addition of adjunctive HA ≥ 0.8% led to an improvement in PPD, but the reduction in BOP was less consistent. Biochemical markers indicated less inflammation, oxidative stress, and selective antimicrobial activity. …”
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