Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital by Büşra Tezcan, Müçteba Can, Çilem Bayındır Dicle, İbrahim Mungan, Derya Ademoğlu

“…In this study, we evaluated the predictive factors of in-hospital mortality for patients who were subjects of RRS activation in a newly established major hospital in Turkey.Materials and Methods:Data on RRS activations were reviewed from paper charts and electronic medical records between March 2019 and February 2020. …”
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Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial by Alessandra Borgognone, Anna Prats, Anna Prats, Ashish Arunkumar Sharma, Ignacio Martinez-Zalacaín, Ignacio Martinez-Zalacaín, Carles Soriano-Mas, Carles Soriano-Mas, Carles Soriano-Mas, Christian Brander, Christian Brander, Christian Brander, Christian Brander, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, José Moltó, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Rafick-Pierre Sekaly, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno

“…Furthermore, the three indices and related discriminant features correlated negatively with functional outcomes, such as quality of life and daily functioning, and positively with depression, stress and CNS-related symptoms before RMD administration, while these associations became less discernible at the subsequent timepoints.ConclusionsWhile the direct effect of the intervention on the observed shifts cannot be conclusively determined in this study settings, these findings strengthen the link between gut bacteria, related metabolites, and neurocognitive function in PWH, and provide an analytical framework for future validation studies aimed at discovering predictive biomarkers for neurocognitive impairment in PWH.…”
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Estimation of Longitudinal and Transverse Elastic Moduli of Native Brazilian Woods by Static Bending Tests by Fabricio da Silva Aguiar, Guilherme dos Santos Silva, Herisson Ferreira dos Santos, Elvys Dias Reis, Francisco Antonio Rocco Lahr, André Luis Christoforo

“…The results showed that, for L/h ratios below 18, the apparent modulus of elasticity was significantly affected by shear effects, exhibiting reductions of up to 18.47%. The E/G ratio ranged from 14.84 to 21.15, corresponding to a reduction of up to 7% and an increase of up to 32%, respectively, about the value proposed by ABNT NBR 7190-1 (2022). …”
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Machine Learning for the Photonic Evaluation of Cranial and Extracranial Sites in Healthy Individuals and in Patients with Multiple Sclerosis by Antonio Currà, Riccardo Gasbarrone, Davide Gattabria, Nicola Luigi Bragazzi, Giuseppe Bonifazi, Silvia Serranti, Paolo Missori, Francesco Fattapposta, Carlotta Manfredi, Andrea Maffucci, Luca Puce, Lucio Marinelli, Carlo Trompetto

“…Classification models achieved perfect performance (accuracy = 1.00), and cortical site regression models showed strong predictive power (EDSS: R²_CV = 0.980; FSS: R²_CV = 0.939). …”
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Transcriptome Analysis of the <i>CML</i> Gene Family in <i>Bletilla striata</i> and Regulation of Militarine Synthesis Under Sodium Acetate and Salicylic Acid Treatments by Kunqian Li, Mengwei Xu, Qingqing Li, Hongwei Li, Ya Xu, Delin Xu

“…Evolutionary analysis showed that <i>BsCML</i> genes are stable and conserved, while functional predictions indicated involvement in environmental stress response, hormone regulation, and circadian rhythms. …”
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Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation by Yongzhi He, Yongzhi He, Yongzhi He, Jiachun Lu, Yushan Luo, Rizhao Pang, Xiaoming Hu, Lijuan Ding, Hua Xiao, Yunyun Wang, Wenchun Wang

“…The interaction between the compound and the target was analyzed through bioinformatics analysis, molecular docking, and molecular dynamics simulation. Finally, the prediction results were verified by simulating spinal cord injury through oxygen–glucose deprivation (OGD) injury in PC12 cells.ResultsInitial screening indicated 13 core targets involved in mitigating SCI. …”
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Vibration of Elastic Functionally Graded Thick Rings by Guang-Hui Xu, Huai-Wei Huang, Yong-Qiang Zhang

“…The derived results were verified by those in literatures which reveals that the present theory can be appropriate to predict the free vibration characteristics for quite thick rings with the radius-to-thickness ratio from 60 down to 2.09. …”
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Psychological study of personal readiness for change and actual functional states of adolescents by С. Бапаева, А. Касымжанова, Т. Черникова, А. Альмуратова, Л. Ермекбаева

“…This study contributes to the understanding of the main factors affecting the personal development of adolescents and their psychological stability, and also contributes to improving the effectiveness of psychological support programs in the educational process. Keywords: personal readiness, functional conditions, stress, fatigue, psychological stability. …”
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Exploring ribosome biogenesis in lung adenocarcinoma to advance prognostic methods and immunotherapy strategies by Zipei Song, Yuheng Wang, Miaolin Zhu, Pengpeng Zhang, Zhihua Li, Xin Geng, Xincen Cao, Jianan Zheng, Jianwei Tang, Liang Chen

“…Compared to other prognostic models, RBS demonstrated superior performance in prognosis prediction. The low-RBS group exhibited a tumor microenvironment (TME) more favorable for efficient immune monitoring and reaction, higher responsiveness to immunotherapy, and a better prognosis. …”
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Awareness among Women about Epidural Analgesia in Riyadh, Saudi Arabia by Sarah W. Alnosaier, Asrar A. Alahmadi, Sarah W. Alnafe, Bandar S. Alshehry

“…This experience may cause physical and/or psychological stress before and during the birth process. Part of the stress a woman may experience relates to the pain endured during labor. …”
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Multi-omics investigation of metabolic dysregulation in depression: integrating metabolomics, weighted gene co-expression network analysis, and mendelian randomization by Wu Qianhao, Wu Qianhao, Zhang Jinwen, Zhang Jinwen, Miao Jingjie, Miao Jingjie, Chen Xiaoyu, Zhao Yangfei, Yao Wenxiu, Jiang Xu, Wang Xiaojun, Han Peipei, Guo Qi, Guo Qi

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Current status and trends in the study of intestinal flora in cognitive disorders: a bibliometric and visual analysis by Qi Zhang, Zhenmei Gao, Yunqing Deng, Xiangqing Xu, Wenyu Sun, Rui Liu, Tianao Zhang, Xilei Sun

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ACAA2 Protects Against Cardiac Dysfunction and Lipid Peroxidation in Renal Insufficiency with the Treatment of S-Nitroso-L-Cysteine by Zhengqi Xu, Feng Jiang, Xiaofan Wu, Bowen Ren, Cuntai Zhang, Li Lin, Sheng Li

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Industrial heat island and carbon emissions: machine learning-based environmental impact assessment in Cilegon, Indonesia by Agus Suprijanto, Yumin Tan, Muhammad Kamran Lodhi, Rodolfo Domingo Moreno Santillan, Isiaka Lukman Alage, Gonzalo Rodolfo Pena Zamalloa

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Olympic combat sports and mental health in children and adolescents with disability: a systematic review of controlled trials by Youngjun Lee, Flavia Guidotti, Flavia Guidotti, Laura Capranica, Caterina Pesce, Valentin Benzing, Janet Hauck, Simone Ciaccioni, Simone Ciaccioni

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The Influence of Maternal Sense of Coherence on 15-year-old Adolescent's Oral Health Outcomes: A Cross-sectional Analysis by Sonali Saha, Sushant Mohanty

“…Public health strategies should focus on enhancing maternal SOC through educational initiatives, stress management, and community support. …”
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Behavioral Characteristics of Limnoperna fortunei under Different Light Conditions by MA Jun, TAO Ze-yi, WANG Ying-cai, WANG Zhang-peng, LI Tian-cui

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From Oblique Thrust to Strike-Slip Fault: Progressive Stages of an Accretionary Wedge Development by Martin Šuťjak, Rostislav Melichar, Ivo Baroň, Yi-Chin Chen, Jan Černý, Jia-Jyun Dong, Václav Dušek, Filip Hartvich, Jan Klimeš, Lenka Kociánová, Tùng Nguyễn, Vladimír Opletal, Matt Rowberry, Chia-Han Tseng

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Genome-wide study and expression analysis of soybean ERF transcription factors and overexpression of GmERF205 enhances drought resistance in soybean by Nan Wu, Yongqi Feng, Tao Jiang, Zhaobo Li, Yulan Liu, Minghao Yuan

“…Furthermore, we predicted that this transcription factor would be localized in the nucleus, a hypothesis that was confirmed by subcellular localization experiments. …”
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Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions by David C. Seaberg, Jamie McKinnon, Lyn Haselton, Patrick Palmieri, Jason Kolb, Suman Vellanki, Mary Moran, J. Chika Morah, Nicholas Jouriles

“…Baseline surveys indicated moderate symptom severity for depression and anxiety. The Post-Traumatic Stress Disorder Checklist (PCL-5) scores showed significant traumatic stress. …”
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