Inflammation-Induced Klotho Deficiency: A Possible Key Driver of Chronic Kidney Disease Progression by Liang Y, Zhang Q, Qian JR, Li SS, Liu QF

“…However, the mechanism regarding their relationship is still unclear. The reduction in Klotho due to inflammation may be attributed to epigenetic mechanisms, such as DNA methylation, histone deacetylation, transcription factor, microRNA (miRNA) regulation and long non-coding RNA (lncRNA) regulation or non-epigenetic factors, such as endoplasmic reticulum (ER) stress and ER-associated degradation (ERAD), which affect Klotho protein metabolism. …”
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DP600 Steel Stampability Analysis Through Microstructural Characterization by Electron Backscatter Diffraction and Nanoindentation by Rafael Guetter Bohatch, Alex Raimundo de Oliveira, Chetan P. Nikhare, Ravilson Antonio Chemin Filho, Paulo Victor Prestes Marcondes

“…To combine vehicle mass reduction with improved performance in deformations in cases of impact, a new family of advanced steels is present, AHSS (Advanced High-Strength Steels). …”
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Perioperative Changes in the Pituitary-Adrenal and Pituitary-Thyroid Systems and Their Correction in Females with Severe Gestosis by V. M. Zhenilo, I. V. Mikhno

“…Progression of gestosis to its severe degree is accompanied by a relative reduction in the functional capacities of the pituitary-adrenal system and thyroid. …”
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Lateral Performance of Steel–Concrete Anchors Embedded in RC Columns Subjected to Fire Scenario by Amer Alkloub, Mahmoud Dwaikat, Ahmed Ashteyat, Farouq Sammour, Asala Jaradat

“…Fire exposure results in a larger reduction in the initial residual lateral stiffness of the SMF specimens when compared to IMF specimens. …”
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Assessing the Impact of Spraying an <i>E. faecium</i> Probiotic at Hatch and Supplementing Feed with a Triple-Strain <i>Bacillus</i>-Based Additive on BCO Lameness Incidence in Bro... by Khawla Alharbi, Anh Dang Trieu Do, Abdulaziz Alqahtani, Ruvindu Perera, Alexa Thomas, Antoine Meuter, Adnan Ali Khalaf Alrubaye

“…The combined treatment resulted in the statistically highest reduction in lameness incidence, indicating a synergistic rather than merely additive effect compared to individual treatments. …”
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Comparative Potential of Zinc Sulfate, L-Carnitine, Lycopene, and Coenzyme Q10 on Cadmium-Induced Male Infertility by Ayesha Iftikhar, Muhammad Furqan Akhtar, Ammara Saleem, Amjad Riaz, Mehrukh Zehravi, Md. Habibur Rahman, Ghulam Md Ashraf

“…Treatment of cadmium-exposed rats with lycopene, LC, CoQ10, and LC-CoQ10 improved sperm count and motility through reduction of testicular oxidative stress and improving serum testosterone.…”
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Efficacy of 20 min yoga module for reducing burnout among healthcare workers: protocol of randomised control trial and results of pilot study by Monika Pathania, Vartika Saxena, Bela Goyal, Apar Avinash Saoji, Vikas Upadhyay

“…Cortisol levels showed trends of reduction but were not significant. These results inform the upcoming main trial. …”
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Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway by Nan Yan, Gaofu Li, Linglin Zhao, Qijing Guo, Jie Yang, Jianhong Liu, Wei Zhou, Yue Gao, Yue Gao, Yushuang Luo, Yushuang Luo

“…The UCSC and JASPAR databases predicted Nrf2 binding sites in the GGTLC2 promoter. …”
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ROS-responsive death receptor 5 fusion protein nano-delivery system enhances myocardial ischemia-reperfusion injury protection by Xiaoyu Liang, Yang Zhang, Changduo Wang, Huiyang Li, Quan Li, Yicong Ye, Chenchen Tu, Xiliang Zhao, Jing Yang, Yong Zeng

“…The microenvironment characterized by inflammation and oxidative stress plays a crucial role in the pathogenesis of myocardial ischemia-reperfusion (I/R) injury. …”
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Decoding the GRAS code: evolutionary phylogeny and functional diversification of a key gene family in Populus simonii by Junbo Chen, Guowei Yao, Xinru Bi, Yishuang Ren, Luping Jiang, Xiaoyu Xie, Lu Han, Wanying Chen, Yi Hao, Kewei Cai, Dandan Zhang, Xiyang Zhao

“…Notably, PSGRAS20 was identified as a central hub in the predicted protein–protein interaction network, implying a potential regulatory role in coordinating the expression of other GRAS family members. …”
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An Enhanced Focal Mechanism Catalog of Induced Earthquakes in Weiyuan, Sichuan, from Dense Array Data and a Multitask Deep Learning Model by Junhao Song, Weiqiang Zhu, Jinping Zi, Hongfeng Yang, Risheng Chu

“…From predicted P polarities and measured S/P ratios, 20,740 focal mechanisms of varying qualities are then computed. …”
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Evaluating Coll2-1NO2 Level in Pre- and Post-menopausal Iraqi Women with Osteoarthritis by Noor Basil Ghanim, Bushra Faris Hasan

“…Coll2-1NO2 is a specific sequence of amino acids produced from the degradation of type II collagen, which is abundantly found in the cartilage, followed by a nitration in the tyrosine residue as a consequence of stress-inflammatory events. In this study, Coll2-1NO2 is used as a biomarker of OA to predict the inflammatory stress condition as well as the cartilage degradation in pre- and post-menopausal women. …”
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Structure and function of the topsoil microbiome in Chinese terrestrial ecosystems by Yuqiang Li, Yuqiang Li, Yuqiang Li, Yulong Duan, Yulong Duan, Yulong Duan, Junbiao Zhang, Evangelos Petropoulos, Jianhua Zhao, Fasi Wu, Lilong Wang, Lilong Wang, Yun Chen, Yun Chen, Xuyang Wang, Xuyang Wang, Xuyang Wang

“…This work provides a predictive framework and actionable genetic targets (e.g., specific CAZyme, N/S cycling genes) for potentially manipulating soil microbiomes to enhance ecosystem resilience and biogeochemical functions under stress.…”
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Under Pressure: Gifted Students’ Vulnerabilities, Stressors, and Coping Mechanisms Within a High Achieving High School by Addison Helsper, Lillian DeShon, Laura E. Boylan, James Galliher, Lisa DaVia Rubenstein

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Characterization of unsaturated coarse-grained railway embankment fill: Water retention and dilatancy by Yuanjie Xiao, Wenqi Li, Liuxin Chen, Xiaoming Wang, Yunbo Li, Pan Tan, Jiapei Du

“…A novel modified dilatancy equation was proposed, which enhances the predictability of CREFMs' responses under variable loading, particularly at high stress ratios defined by the deviatoric stress over the mean effective stress. …”
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Particle-based simulation technique for medical applications by Su-Kyung Sung, Sang-Won Han, Byeong-Seok Shin

“…This paper proposes a particle-based elastic object simulation technique to model the debris from torn tissue when making an incision in the organs. It can predict where the tissue will tear based on the maximum shear stress (MSS) theory and Tresca’s yield criterion when the force applied to the tissue exceeds the maximum stress. …”
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Measuring social inequalities in self-reported miscarriage experiences in the United Kingdom by Heini Väisänen, Katherine Keenan

“…A social gradient in the risk of miscarriage may be related to societal structures shaping risk factors, such as stress, health behaviours, and age at pregnancy. We use the British Cohort Study (1970) to investigate whether individuals’ socioeconomic characteristics are associated with their likelihood of self-reporting a miscarriage over the reproductive life course. …”
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The USGT Method for Suspender Tensioning of Self-Anchored Suspension Bridges by Hongmei Tan, Zhujian Hou, Zhou Qiu, Junlin Ji, Dahan Chen

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Strength and Range of Motion of Internal and External Rotator Muscles in Volleyball Players With and Without Uneven Shoulders by Abdolrasoul Daneshjoo, Tavoos Hosseini

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Substance abuse as a cause of violence in persons diagnosed with schizophrenia by Dimitrijević Aleksandar, Živković Anja, Božović Maša

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