Anticancer activity of triterpene glycosides from the sea star Solaster pacificus by Sergey A. Dyshlovoy, Jessica Hauschild, Malte Kriegs, Konstantin Hoffer, Olga Y. Burenina, Nadja Strewinsky, Timofey V. Malyarenko, Alla A. Kicha, Natalia V. Ivanchina, Valentin A. Stonik, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg

“…To explore the mechanism of anticancer activity of cucumarioside C1, we performed functional kinome profiling of treated 22Rv1 cells, predicting activation of kinases involved in stress response and survival (IKKα, IKKβ, IKKε), necroptosis (MLKL), metabolism (GCN2, PDK1), cytoskeletal dynamics (RHOK), mitophagy (PINK1), apoptosis and cell cycle regulation (PITSLRE), and immune modulation (COT). …”
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Renal aging and its consequences: navigating the challenges of an aging population by Meiqi Zhang, Haifeng Ni, Yumeng Lin, Ke Wang, Tingke He, Lan Yuan, Zhongyu Han, Xiaohong Zuo, Xiaohong Zuo, Xiaohong Zuo

“…These changes lead to a sustained reduction in renal filtration, reabsorption, secretion, as well as endocrine function, which in turn affects overall health. …”
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Evaluating the Role of Coenzyme Q10 in Migraine Therapy—A Narrative Review by Anna Fajkiel-Madajczyk, Michał Wiciński, Zuzanna Kurant, Józef Sławatycki, Maciej Słupski

“…Supplementation with CoQ10 in a wide range of doses has resulted in many therapeutic benefits in subjects, including a decrease in the frequency and duration of migraine attacks, a reduction in nausea, a lower maximum pain during an attack, and fewer days with migraine. …”
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RSM-based optimization of recycled aggregate concrete with pozzolanic materials under high temperatures by Muhammad Saqib Khan, Aman Ulhaq, Deema Mohammed Alsekait, Muhammad Faisal Javed, Mohammed Jameel, Hisham Alabduljabbar, Diaa Salama Abdelminaam

“…Results showed that SCMs improved tensile strength by up to 12% in RAC25 and helped retain strength at elevated temperatures, despite some reduction in compressive strength due to thermal stress. …”
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Anticancer Activity of Cerium Oxide Nanoparticles Towards Human Lung Cancer Cells by Nithin Krisshna Gunasekaran, Nicole Nazario Bayon, Prathima Prabhu Tumkur, Krishnan Prabhakaran, Joseph C. Hall, Govindarajan T. Ramesh

“…The cytotoxicity and proliferation inhibition of these nanoparticles were assessed using MTT and Live/Dead assays, revealing a dose-dependent reduction in cell viability. Additionally, reactive oxygen species (ROS) generation was quantified through ROS assays, confirming oxidative stress induction as a key mechanism of cytotoxicity. …”
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Growth and Physiological Responses of Dendrocalamus asper as Influenced by Different Water Application by Zainol Haida, Ruzana Sanusi, Hafidz Khairul Hisham, Sheriza Mohd Razali, Hazandy Abdul Hamid

“…Increasing yields while maintaining effective cost management is essential for planters. However, water stress possesses a significant challenge which can potentially disrupt bamboo growth and its physiological responses and thus the plant productivity. …”
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Effect of 9,9′-Bis(aryl)fluorene-modified Nanocellulose, Bamboo, and Bagasse Fibers on Mechanical Properties of Various Polymer Composites by Takumi Takeuchi, Panuwat Luengrojanakul, Hiroshi Ito, Sarawut Rimdusit, Shinichi Shibata

“…Nonetheless, it exhibited less reduction in elongation compared to composites where bamboo or FCF was added to other polymers. …”
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Ancient Grains as Functional Foods: Integrating Traditional Knowledge with Contemporary Nutritional Science by Jude Juventus Aweya, Drupat Sharma, Ravneet Kaur Bajwa, Bliss Earnest, Hajer Krache, Mohammed H. Moghadasian

“…Their health-promoting effects are underpinned by multiple interconnected mechanisms, including the reduction in oxidative stress, modulation of inflammatory pathways, regulation of glucose and lipid metabolism, support for mitochondrial function, and enhancement of gut microbiota composition. …”
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Effect of Heat Treatment on Microstructure and Mechanical Properties of (TiB + TiC) /Ti-6Al-4V Composites Fabricated by Directed Energy Deposition by Hai Gu, Guoqing Dai, Jie Jiang, Zulei Liang, Jianhua Sun, Jie Zhang, Bin Li

“…Annealing promotes decomposition of acicular martensite and stress relaxation, leading to a reduction in hardness compared to the as-deposited state. …”
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Oxidation characteristics of Ti-6Al-4V machining scraps and their influence on microstructure and fracture behavior in recycled alloys by Zhang Keren, Tian Shuai, Zhang Yuzhe, He Junli, Zhang Nailu, Wang Lei, Zhang Xiaoyong

“…These compositional differences give rise to an increase in the β phase content and a reduction in the internal stress within the recycled alloy, leads to a different fracture behavior. …”
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Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions by Cristina Visentin, Giulia Rizzi, Wen Yin, Mathilde Hotot, Dipambita Roy, Torbjörn Gräslund, Riccardo Capelli, Stefano Ricagno

“…In parallel, in presence of one of the affibody (Zβ2m_01) a significant reduction in β2m aggregation was observed. The inhibition of amyloid formation was also confirmed by transmission electron microscopy. …”
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The role of city parks in creating ‘wellbeing societies’: A case study of Piłsudski Park in Łódź, Poland by Melanie Kay Smith, Joanna Kowalczyk-Anioł, Jakub Janiszewski, Karolina Grabarczyk

“…Findings reveal that physical activities, such as walking, are the primary motivation for park visits, while mental benefits like relaxation and stress reduction are highly valued outcomes. Although social interactions are rated lower overall, they are particularly significant for younger and older users, as well as marginalized groups such as unemployed individuals. …”
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Optimization of Anesthetic Provision During Operations on the Foot by D. S. Yasnev, A. V. Zabusov, S. V. Larionov, P. A. Lyubashevsky, P. S. Zhbannikov

“…In comparison with the control, got prolongation of effective spinal anesthesia, decrease of intensity of a postoperative painful syndrome that marked according to a visual analog scale, increase of thresholds of painful sensitivity by the data of electrosensometriya, improvement regional haemocirculation and microcirculation be the date of ultrasonic dopplero-graphia and electrothermometry of a stops skin. Stress — limiting action of a preparation was showed including reduction in comparison with the control leucocitosis and neutrophil shift of leucocitar formulas in the postoperative period, absence of episodes hiperglicemiya. …”
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Stochastic Effect of Grain Elongation on Nanocrystalline Materials Strain and Strain Rate Produced by Accumulative Roll-Bonding and Equal Channel Angular Pressing by P. Baonhe Sob, A. Alfayo Alugongo, T. Ba Bob Tengen

“…Materials with high curvature grains have more enhanced yield stress. Reducing strain rates leads to materials with more enhanced yield stress, with critical strain rates values beyond which further reductions do not lead to yield stress enhancement. …”
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The effect of terpinen-4-ol in controlling blueberry fruit rot causing by Alternaria tenuissima by Yuxuan Li, Jiaqi Wang, Sixu Lin, Ling Yang, Bingxin Sun, Yunhe Zhang, Yufeng Xu, Xuerui Yan

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Effects of endurance exercise and dietary protein intake on osteokine, bone turnover, and inflammatory markers in endurance runners: A narrative review by Sofia Valente Ferreira, Silar Gardy, Tyler A. Churchward-Venne, Andrea R. Josse, Jenna C. Gibbs

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TECHNIQUES OF "COMPETITIVE PAIRS" WHILE TRAINING DENTAL DOCTORS by V. V. Ekhalov, A. V. Samoilenko, I. A. Romanyuta

“…The introduction of stimulating, encouraging, exciting methods in the educational process can remove psychological stress from interns' doctors, encourage them to self-improvement. …”
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Analysis of Slope Stability in Ion-Adsorption Rare Earth Mine Under In Situ Leaching Condition by Wenyao Yuan, Hongwei Wang, Daoyuan Sun, Fang Yan, Chuanzheng Liu, Xinguang Zhang, Longjun Dong

“…The leaching solutions engage in a physical–chemical coupling effect with the rare earth ores, which diminishes the strength parameters of weathered ore layers. This reduction in strength leads to a decrease in the stability of the slope and an increased risk of landslides, significantly contributing to instability and damage within rare earth mines. …”
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Study on interlayer damage and shear behavior of CFRP twill interlocking and CFRP unidirectional fiber bridging by Di Gai, Shengjie Yu, Lin Huo, Zhipeng Yao, Shiyu Yang, Mingyang Wang, Xuguang Zhang

“…The results demonstrated that hybrid layering led to a notable reduction in bending beam strength due to increased interlaminar shear stress, resulting in delamination and damage within the UD layers. …”
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Effect of Polypropylene Microplastic and Florfenicol Antibiotic on Some Hormonal and Haematological Biomarkers in Yellowfin Seabream (Acanthopagrus latus) by Mehrnaz Shirmohammadi, Farahnaz Kianersi, Nima Shiry, Fatemeh Hekmatpour

“…The groups administered MPs, individually or collectively, exhibited a reduction in thyroid hormones. These findings indicate that both MPs and FFC induce anemia and stress in yellowfin seabream, with co-exposure exacerbating these effects. …”
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