Emerging phenotype: Maturity-onset diabetes of the young type 5 (MODY-5) – mechanisms, clinical spectrum, and unmet needs by Fahrul Nurkolis, Rony Abdi Syahputra, Andika Priamas Nugrahanto, Nurpudji Astuti Taslim, Arifa Mustika, Raymond Rubianto Tjandrawinata, Dante Saksono Harbuwono, Sidartawan Soegondo

“…Molecular disruptions prominently include alterations in NF-κB signaling pathways, increased oxidative stress, mitochondrial dysfunction, and heightened profibrotic TGF-β activity, leading to early and severe multisystem complications. …”
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Effect of multi-walled carbon nanotube exposure on the expression pattern of genes involved in silymarin synthesis pathway in Silybum Marianum L. by Forough Asakereh, Alireza Etminan, Reza Azizinezhad, Mansour Ghorbanpour, Alireza Pour-Aboughadareh

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Profilin Pfy1 is critical for cell wall integrity and virulence in Candida albicans by Xun Sun, Yueqing Wang, Xiaomin Yang, Xi Xiang, Lili Zou, Xiaowen Liu, Gang Luo, Qi Han

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Peritraumatic distress and its association with resilience among a sample of war-exposed Palestinian population: a cross-sectional study by Suheir S. Sabbah, Hamzeh Yacoub, Rita Yacoub, Zaid Yacoub, Khalil Sabbah, Yousef B. Ghannam

“…Higher PTD was significantly associated with higher resilience (B = 0.3, β = 0.301, p < 0.001), a finding that may reflect adaptive coping processes in highly stressful environments. Additional predictors of resilience included age, educational level, employment status, and health condition. …”
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Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil by R. P. Mason

“…The underlying cause of CV disease is atherosclerosis, a chronic inflammatory process that is clinically manifested as coronary artery disease, carotid artery disease, or peripheral artery disease. It has been predicted that atherosclerosis will be the primary cause of death in the world by 2020. …”
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A Numerical Method for Blast Shock Wave Analysis of Missile Launch from Aircraft by Sebastian Heimbs, Josef Ritzer, Johannes Markmiller

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Thermoelastic waves in an infinite solid caused by a line heat source by Ranjit S. Dhaliwal, Samir R. Majumdar, Jun Wang

“…Our results show that this theory predicts an infinite speed for heat propagation in general, and includes the second sound phenomena as a special case.…”
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Anxiety unplugged: Effectiveness of an unguided, transdiagnostic, web-based intervention for anxiety disorders—A randomized controlled trial by Anna Baumeister, Lea Schuurmans, Steffen Moritz

“…Results: Significant post-intervention reductions in anxiety, stress, and depression were found in the intervention group compared to controls at small to medium effect sizes (|Hedges's g| = 0.27–0.35). …”
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The relationship of within-individual and between-individual variation in mental health with bodyweight: An exploratory longitudinal study. by Julia Mueller, Amy L Ahern, Rebecca A Jones, Stephen J Sharp, Alan Davies, Arabella Zuckerman, Benjamin I Perry, Golam M Khandaker, Emanuella De Lucia Rolfe, Nick J Wareham, Kirsten L Rennie

“…It is, therefore, unclear how small fluctuations in mental wellbeing within individuals predict bodyweight over short time periods, e.g. within the next month. …”
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Effects of Coping, Affirmation, Resilience, and Empowerment (CARE)Program on Depression, Mental Health Literacy, and Coping Skills among People with Depression in Indonesia: A Mixe... by Lafi Munira, Pranee Liamputtong, Pramon Viwattanakulvanid

“…We combined psychoeducation and coping skills to help people with depression cope with depressive symptoms and stressful life events. This study investigated the effects of CARE program on participants’ depression scores reduction, mental health literacy, and coping skills improvement. …”
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Fatigue Analysis of Random Vibration for Converter Cabinet by DING Jie, TANG Yutu

“…The fatigue life is predicted in frequency domain according to the results of frequency response analysis on the finite element of the converter’s cabinet and the ASD(Acceleration Spectral Density) spectrum from the standard GB/T 21563-2008 Railway applications- Rolling stock equipment- Shock and vibration tests. …”
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Comprehensive Analysis of Neural Network Inference on Embedded Systems: Response Time, Calibration, and Model Optimisation by Patrick Huber, Ulrich Göhner, Mario Trapp, Jonathan Zender, Rabea Lichtenberg

“…This is particularly important in applications such as predictive maintenance, which rely on timely state change predictions. …”
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The needs and unmet needs for people living with dementia, caregivers and care workers in dementia health care systems: a systematic review by Michele Sorrentino, Michele Sorrentino, Michelangelo Mercogliano, Claudio Fiorilla, Irene Stilo, Federica Esposito, Marcello Moccia, Marcello Moccia, Luigi Lavorgna, Giuseppina Affinito, Elena Salvatore, Maria Pia Sormani, Anna Odone, Anna Odone, Azeem Majeed, Fabiana Rubba, Maria Triassi, Maria Triassi, Raffaele Palladino, Raffaele Palladino, Raffaele Palladino

“…Psychosocial and emotional support are essential for managing stress and ensuring quality of life. Caregivers demand education about dementia care, progression, and self-care, while healthcare workers need training, and interdisciplinary teams. …”
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TXNIP promotes viral replication by disrupting MAVS-mediated antiviral signaling and serves as a therapeutic target for antiviral therapy by Ruilin Chen, Wenyu Wu, Jiajia Han, Qiyun Lei, Jiawan Chen, Dan Guo, Chan Wang, Xiaodong Tang, Min Zou, Shuwen Liu, Xingang Yao

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Evaluation of Assembly Gap from 3D Laser Measurements via FEA Simulation by Xueshu Liu, Junhao Chang, Yuxing Yang, Yiqi Wang, Yongjie Bao, Hang Gao

“…This paper develops a numerical process for gap prediction before the assembly step. After the assembly components are scanned in a specified configuration, finite element meshes are created using the scanned data and the shape variations of each component caused by constraints and forces in different configurations are evaluated by finite element analysis. …”
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The roles of NHEJ and TLS pathways in genomic alterations and phenotypic evolution in the yeast Yarrowia lipolytica by Cen Yan, Ye-Ke Wang, Yuan-Ru Xiong, Xin-Qiu Zhou, Yuan-Chun Fang, Ruo-Tian Nie, Cunqi Ye, Ke Zhang, Dao-Qiong Zheng

“…Here, we investigate how these two pathways contribute to spontaneous and genotoxic stress–induced genomic alterations in the yeast Yarrowia lipolytica. …”
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Acute Coronary Syndrome in Patients With 2 Type Diabetes Mellitus (Review of Literature; Description of the Clinical Case) by Bilous Z., Abrahamovych О., Mazur N., Ryabokon S., Ilenkiv N., Bevza N.

“…The effect of each individual pathogenic marker on the clinical course and complications of these patients remains undetermined; therefore, the study of the clinical course of ACS with comorbid type 2 diabetes mellitus and the prediction of complications are important for improving the prognosis in these patients. …”
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Trade-off strategies between drought resistance and growth rate of dominant tree species in karst forests within heterogeneous habitats by Jing Wang, Bin Wang, Denghui Wang, Yanping Dong, Jianxing Li, Fang Lu, Wanglan Tao, Yili Guo, Wusheng Xiang, Meilan Wen, Xiankun Li

“…These results provide a multidimensional framework for balancing stress resistance and productivity in tropical karst vegetation restoration.…”
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Evaluating an early Interdisciplinary Multimodal Assessment for Patients at Risk of Developing Chronic Pain: Results of a Multicentre RCT in Germany by Daniel Szczotkowski, Sandra Meyer-Moock, Thomas Kohlmann, Karin Deppe, Anne Gärtner, Greta Hoffmann, Thomas Isenberg, Gabriele Lindena, Ursula Marschall, Carolin Martin, Beatrice Metz-Oster, Lena Milch, André Möller, Bernd Nagel, Frank Petzke, Anke Preissler, Julia Pritzke-Michael, Leonie Schouten, Katja Schwenk, Catharina Schumacher, Anja Waidner, Ulrike Kaiser

“…Results A total of 620 (68.4%) valid questionnaires were available at the 6-month follow-up. The mean reduction (numerical rating scale, 0–10) in terms of improvement within both groups (IG/CG) was 1.6/1.7 points for PI and 1.9/1.8 points for DS. …”
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Identification of genetic locus with resistance to take-all in the wheat-Psathyrostachys huashanica Keng introgression line H148 by Sheng-sheng BAI, Han-bing ZHANG, Jing HAN, Jian-hui WU, Jia-chuang LI, Xing-xia GENG, Bo-ya LÜ, Song-feng XIE, De-jun HAN, Ji-xin ZHAO, Qun-hui YANG, Jun WU, Xin-hong CHEN

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