Characterization and dissolution test of recrystallized mefenamic acid by fast cooling methods by La Ode Akbar Rasydy, Hilda Damayanti, Erza Satrio, Jaka Supriyanta

“…Mefenamic acid, classified as a Biopharmaceutics Classification System (BCS) Class II drug, exhibits high permeability but low dissolution rates, limiting its bioavailability. This study aims to enhance the dissolution rate of mefenamic acid through crystal structure modification using fast cooling recrystallization with three distinct solvents: acetone (AMA), ether (AMEt), and ethyl acetate (AME). …”
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Short-term physiological responses of Pinus koraiensis Siebold & Zucc. and Chamaecyparis obtusa (Siebold & Zucc.) Endl. seedlings to elevated CO2 by Iereh Kim, Myeongja Kwak, Juyeong Kim, Suyoung Woo

“…C. obtusa initiated early biochemical adjustments, indicated by increased biochemical parameters of photosynthesis (maximum carboxylation rate, Vcmax; electron transport capacity, Jmax; and triose phosphate utilization, TPU), yet required more time for these changes to result in higher photosynthetic rates. …”
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Effect of COVID-19 lockdowns on maxillofacial fractures in New Zealand: a retrospective study by Chelsea A Allen-Brough, Rahul Jayakar, Dalice Sim, Craig A MacKinnon, Swee T Tan

“…During COVID-19 lockdowns, there was a relative increase in the referral rates of females aged 60 years and over. Both sports and interpersonal violence showed significantly reduced referral rates during lockdowns, while falls, road traffic accidents and other were referred at a similar rate as out of lockdown.…”
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Geographic distribution and trends of small-area burn claims in Japan: An analysis using NDB open data from 2014 to 2021 by Takeshi Utsunomiya, Takahiro Ueda

“…Introduction Burns are a major global health issue, causing approximately 180,000 deaths annually and leading to high morbidity rates. The Japan Trauma Data Bank Report 2022 recorded 1749 burn cases, with a mortality rate of 17.6%. …”
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Impact of Sex and Age on Trends of Mortality From Infective Endocarditis in High-Income Countries by Makoto Hibino, MD, MPH, PhD, Hiroki A. Ueyama, MD, Raj Verma, Hwee Teoh, PhD, Bobby Yanagawa, MD, PhD, Deepak L. Bhatt, MD, MPH, MBA, Subodh Verma, MD, PhD

“…Conclusions: Mortality rate from infective endocarditis is increasing in most countries, with varying patterns and degrees of changes observed in relation to sex and age. …”
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Evaluating anti-MRSA antibiotic stewardship with a focus on trends in consumption and resistance in a tertiary hospital in Alexandria, Egypt from 2019 to 2023 by Ehab Elmongui, Adel Zaki, Amel Elsheredy, Asmaa Abd Elhameed

“…The study compared these consumption patterns with resistance rates in Staphylococcus spp., including MRSS, from January 2020 to December 2023. …”
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Cancer incidence and mortality in the Far Eastern Federal District (2013–2022) by V. P. Gordienko

“…The average cancer incidence rate in males was 294.06 ± 5.05 per 100,000 (2020: 296.94 ± 4.66), with a decrease rate of 3.0 %. …”
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Treatment failure of pentavalent antimonial therapy for human visceral leishmaniasis: a meta-analysis by Caitlin M Jones, Susan C Welburn, Joshua D Jones

“…Knowledge of failure rates can inform policy decisions at all levels. …”
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Identification of Earthquake Precursors Origin and AI Framework for Automatic Classification for One of These Precursors by Ghada Ali, Lotfy Samy, Omar M. Saad, Ali G. Hafez, El-Sayed Hasaneen, Kamal AbdElrahman, Ibrahim Salah, Mohammed S. Fnais, Hamed Nofel, Ahmed M. Mohamed

“…From these two stations, 429 earthquakes were recorded at three sampling rates: 50, 100, and 200 samples per second. Then, a spectral analysis was performed, where it was found that there was a clear relationship between the first pattern and the acquisition sampling rate. …”
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The evolution of irreversible cell differentiation under cell death effect. by Yuanxiao Gao, Xueyan Zhao, Caixia Li

“…We show that irreversible differentiation is more likely to occur when cell death rates between cell types are linear. Meanwhile, differences in death rates between cell types affect the emergence conditions of irreversible differentiation, whereas no significant impacts on that from equal cell death rates. …”
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Comparative Analysis of Open and Closed Nasal Fractures in Trauma Settings: Mechanisms, Intent, Surgical Interventions, and Outcomes by Ahmad K. Alnemare

“…Objectives: This study aimed to explore nasal fracture patterns, trauma mechanism and intent, treatment approaches, and mortality rates, offering insights for clinical practice and prevention in trauma settings. …”
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Spatiotemporal Analysis of Disease Spread Using a Soliton-Based SIR Framework for Nomadic Populations by Qura Tul Ain, Xiaoli Qiang, Noor Ul Ain, Zheng Kou

“…Numerical simulations demonstrate the effects of varying key parameters such as transmission rates, recovery rates, and advection–diffusion coefficients on the epidemic’s progression. …”
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Multiple bursts of speciation in Madagascar’s endangered lemurs by Kathryn M. Everson, Luca Pozzi, Meredith A. Barrett, Mary E. Blair, Mariah E. Donohue, Peter M. Kappeler, Andrew C. Kitchener, Alan R. Lemmon, Emily Moriarty Lemmon, Carlos J. Pavón-Vázquez, Ute Radespiel, Blanchard Randrianambinina, Rodin M. Rasoloarison, Solofonirina Rasoloharijaona, Christian Roos, Jordi Salmona, Anne D. Yoder, Rosana Zenil-Ferguson, Dietmar Zinner, David W. Weisrock

“…Our analyses reveal multiple bursts of diversification (without subsequent declines) that explain much of today’s lemur diversity. We also find higher rates of speciation in Madagascar’s lemurs compared to lorisiforms, and we demonstrate that the lemur clades with high diversification rates also have high rates of genomic introgression. …”
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Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study by Wang Q, Wu F, Li T

“…Among Staphylococcus isolates, methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococci (MRCNS) were identified at rates of 51.6% and 88.7%, respectively. The carbapenem resistance rates of K. pneumoniae and E. coli were 28.8% and 4.0%, respectively. …”
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Cancer Genetics in the Arab World by Waleed S. Al Amri PhD, Muna Al Jabri PhD, Aisha Al Abri MS, Thomas A. Hughes PhD

“…Cancer remains a major global health burden, with incidence rates rising globally. The Arab world, which is often regarded as an underrepresented population in literature, shows distinct patterns in cancer incidences, genetics, and outcomes in comparison with Western populations. …”
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Glucose‐Induced Developmental Dynamics: Understanding Male Prevalence in Early Mouse Embryo Stages by Fikri Ardhani, Asako Okamoto, Masayuki Shimada

“…Conclusions Glucose availability accelerated embryonic development and created sex‐specific patterns of developmental timing, with male embryos exhibiting faster progression rates, which might be associated with differential X‐linked PDHA1 metabolic gene expression during early mouse embryogenesis.…”
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Distributed Robust Low-Carbon Economic Dispatch of Power Systems Considering Extreme Scenarios by HU Heng, QIN Jianru, LI Haibo, LIU Jiefeng

“…Particularly， tail risks triggered by extreme weather and the dynamic mismatches between stochastic RE fluctuations and conventional unit regulation rates invalidate conventional deterministic scheduling models reliant on typical scenarios. …”
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Depression among older adults in Norway 1995-2019: Time trends, correlates, and future projections in a population study: The HUNT study. by Maria Lage Barca, Eivind Aakhus, Ellen Melbye Langballe, Thomas Hansen, Ragnhild Holmberg Aunsmo, Geir Selbæk, Steinar Krokstad, Bjørn Heine Strand

“…<h4>Conclusion and implications</h4>Depression rates among adults aged 70 + decreased by 50% from 1995 to 2019, but less so among the oldest old. …”
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Microsaccades and Visual-Spatial Working Memory by Joshua T. Gaunt, Bruce Bridgeman

“…Intervening tasks during the memory interval affected memory as well as microsaccade patterns. Average microsaccade rate peaks after appearance of a fixation cross at the start of a trial, and dips at cue onset and offset. …”
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Global Trajectories of Colorectal Cancer Burden From 1990 to 2021 and Projection to 2040 by Xiaolu Chen, Xuesi Dong, Yadi Zheng, Chenran Wang, Zilin Luo, Jiaxin Xie, Zeming Guo, Xiaoyue Shi, Xinyue Zhu, Yongjie Xu, Wei Cao, Fei Wang, Ni Li

“…Most countries showed slowly increasing incidence rates (49.0%, n = 100) and stable age‐standardized mortality rates (51.0%, n = 104). …”
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