Genomic alterations of marine yeast Scheffersomyces spartinae under spontaneous and mutagenic conditions by Yu-Ting Bai, Awkash Sharma, Qian Xiang, Li-Yan Tian, Ke-Jing Li, Bao-Ying Guo, Lei Qi, Dao-Qiong Zheng

“…Heat stress at 37 °C increased the SNVs and InDels rates to 1.4 × 10⁻¹⁰ and 7.5 × 10⁻¹¹ per base pair per cell division. …”
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Global, regional, and national impact of Down syndrome on child and adolescent mortality from 1980 to 2021, with projections to 2050: a cross-sectional study by Erdengqieqieke Ye, Erman Wu, Erman Wu, Rui Han, Rui Han

“…Despite improvements in life expectancy and quality of life due to medical progress, children and adolescents (under the age of 20 years) with Down syndrome still face higher mortality rates. Future research is essential to elucidate the epidemiological patterns and trends in Down syndrome among children and adolescents, enabling the development of effective prevention and intervention strategies to improve survival and health outcomes.MethodsThis study draws on Global Burden of Disease (GBD) 2021 mortality data for children and adolescents with Down syndrome. …”
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Towards developing new private sector maternity care models in South Africa: results from a deliberative stakeholder dialogue by Tanya Doherty, Sue Fawcus, Vishal Brijlal, Geetesh Solanki

“…Caesarean rates are rising globally, four of the five countries with the highest caesarean rates are middle-income countries and private hospital care is a strong predictor of caesarean birth. …”
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Clinical and survival differences between second primary and first primary nasopharyngeal carcinoma in a retrospective study by Xin Huang, Ying Kong, Tianyu Wu, Zhen Meng, Min Kang

“…Therapeutically, 2nd NPC patients showed significantly lower rates of curative-intent treatment (75.6% vs. 91.3%, p = 0.010), lower rates of good treatment tolerance (86.7% vs. 96.1%, p = 0.068), reduced chemotherapy utilization (73.3% vs. 89.3%, p = 0.014), and less frequent cisplatin use during concurrent chemotherapy (66.7% vs. 84.4%, p = 0.034). …”
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Spatial and spatio-temporal analysis of cancer mortality in Iran: gender disparities and implications for health policy by Alireza Zangeneh, Arash Ziapour, Seyede Negin Hoseini, Babak Nazari, Homa Molavi, Farid Najafi, Ardeshir Khosravi, Reza Heidari Moghadam

“…The standard deviation ellipse indicated a transition in cancer mortality distribution from a northwest-southeast alignment in 2017 to predominantly western and eastern orientations in subsequent years, with varied hotspot patterns across Iran. Conclusions: The study highlights rising cancer mortality rates, particularly among men and premenopausal women, underscoring the need for targeted public health interventions and improved medical infrastructure to enhance prevention and treatment efforts.…”
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The Sociology of Suicide After COVID-19: Assessment of the Spanish Case by Enrique Fernández-Vilas, Juan R. Coca, Juan José Labora González, Marcos Iglesias Carrera

“…This paper aims to explore the impact of the COVID-19 pandemic on suicide rates in Spain, using a theoretical ex post facto analysis. …”
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Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2... by Yuzhou Cai, Guiming Chen, Peng Bai

“…Correlation analyses examined relationships between 22 health workforce categories and disease burden.ResultsGlobally, age-standardized death rates from smoking-related diseases increased by 12.3% from 1990–2021, with males showing higher rates than females across all regions. …”
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Extreme heat and pediatric health in a warming world: a space-time stratified case-crossover investigation in Ontario, Canada by Hallah Kassem, Eric Lavigne, Kate Weinberger, Michael Brauer

“…Conclusions In Ontario, EHEs decreased the rates of pediatric emergency healthcare utilization for injuries and increased the rates of respiratory illnesses, asthma, heat-related illnesses, heatstroke, dehydration, infectious and parasitic diseases, lower respiratory infections, and enteritis. …”
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SARS-CoV-2 Alchemy: Understanding the dynamics of age, vaccination, and geography in the evolution of SARS-CoV-2 in India. by Mansi Patel, Uzma Shamim, Umang Umang, Rajesh Pandey, Jitendra Narayan

“…Geographic analysis emphasizes notable regional variation in substitution rates, potentially driven by population density and local transmission dynamics, while regions with more homogeneous strain circulation show relatively lower substitution rates. …”
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Inequities in mortality and potential years of life lost (PYLL) in greater Santiago, Chile, during and after the COVID-19 pandemic by Claudio Vargas, Paola Salas, Felipe Elorrieta, Valentina Muñoz, Erika Vivanco, Matilde Maddaleno

“…Abstract Introduction In Chile and worldwide, disparities in age-adjusted mortality rates and Potential Years of Life Lost (PYLL) intensified during the initial two years of the COVID-19 pandemic, with low- and middle-income countries experiencing a disproportionate burden. …”
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Spatiotemporal Analysis of Obesity: The Case of Italian Regions by Elena Grimaccia, Luciano Rota

“…During the period under analysis, obesity prevalence rates in Italy show a tendency to grow, with a sharp increase during the COVID-19 lockdown.…”
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Epidemiological trends of dengue disease in Thailand (2000-2011): a systematic literature review. by Kriengsak Limkittikul, Jeremy Brett, Maïna L'Azou

“…Disease incidence and deaths remained highest in children aged ≤ 15 years and case fatality rates were highest in young children. Heterogeneous geographical patterns were observed with higher incidence rates reported in the Southern region and serotype distribution varied in time and place. …”
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Features of myocardial damage at COVID-19 by S. H. Hamidov, A. G. Obrezan, P. S. Lobanova, S. V. Azarenko

“…Some studies also provide comparative data on COVID-19+ and COVID-19- patients, complication patterns, and mortality rates. The results of the studied materials shows that, the frequency of cardiac complications and the number of deaths are significantly more common in patients with concomitant diseases such as arterial hypertension, diabetes mellitus, obesity, CKD, arrhythmias. …”
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Multidrug-resistant pulmonary tuberculosis in Esmeraldas, Ecuador (2018–2022): prevalence and clinical–epidemiological profile from a retrospective observational study by Jaime Angamarca-Iguago

“…Treatment outcomes were incomplete in 41% of cases; among reported outcomes, cure rate was 22.4%, and the case fatality rate was 10.2%. …”
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Analysis of Disease Free Survival and Overall Survival of HER2 Positive Subtype Breast Cancer Patients at Prof. Dr. I.G.N.G. Ngoerah Denpasar Hospital by Gde Ary Putra Kamajaya, Ni Gusti Ayu Agung Manik Yuniawaty Wetan, I Gede Budhi Setiawan

“…Results: The 3-year survival rate was 77.7% and the 5-year survival rate was 74.3%, with median survival times of 31 months (95%CI 30.7-32.86) and 49 months (95%CI 47.85-52.089), respectively. …”
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The effects of annual cycle stages and life-history traits on feather abrasion by Yosef Kiat, Quentin Dupriez, Gina Pyo, Oliver J. L. Fox, Rafi Paz, Hans-Jürgen Eilts, Carlos Talabante, Nir Sapir

“…These findings highlight the importance of moult timing for feather abrasion rate and maintaining plumage integrity during the reproduction season. …”
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Investigating the first case of permafrost degraded subsidence in Lahaul & Spiti region of Tethyan Himalayas by Kirti Kumar Mahanta, Ipshita Priyadarsini Pradhan, Nitesh Dhiman, Ankit Singh, Dericks Praise Shukla

“…The analysis of historical temperature and precipitation data from 1950 to 2024 shows a significant rise in temperature at a rate of 0.02 °C/year and a shift in precipitation pattern over the village. …”
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Global burden of cardiovascular disease due to low physical activity, 1990–2021 by Nan Wu, Jian Wang, Yingchu Hu, Tingsha Du, Peng Shu, Caijie Shen, Xiaomin Chen

“…Three complementary metrics were employed: (1) Age-standardized death rate (ASDR) and (2) Disability-Adjusted Life Year (DALY) rate provided cross-sectional burden estimates, while (3) Estimated Annual Percentage Change (EAPC) quantified temporal trends in ASDR/DALY rates. …”
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Clinical evaluation of negative mNGS reports in sterile body fluids and tissues by Wang Lisha, Qian Jiao, Chen Mengyuan, Qin Jiajia, Tang Tianbin, Wang Yilan, Hu Linjie, Yu Sufei

“…The positive impact rates of clinical application in the plasma, CSF, and others groups were 68.0%, 40.4%, and 25.6%, respectively. …”
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Complementing community science with xenomonitoring: Understanding the eco-epidemiology of Dirofilaria immitis infection in dogs and mosquitoes by Tamara Szentivanyi, Laura V. González, Ágnes Klein, Zoltán Soltész, László Z. Garamszegi

“…Similar to community science results, the highest infection rates were observed in the southeastern and eastern regions (MIR: 14.9 and 11.6, respectively), but the two approaches generally provided overall similar geographical patterns. …”
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