Expression pattern changes of three homeologs in chemokine activity enhance antiviral response to herpesvirus infection in a newly synthesized alloheptaploid by Xiao-Li Yang, Yang Wang, Zhi Li, Qiao-Hong Lin, Peng Yu, Meng Lu, Xi-Yin Li, Zhong-Wei Wang, Xiao-Juan Zhang, Jian-Fang Gui, Li Zhou

“…However, our understanding about the patterns that allopolyploids modify homeolog expression upon pathogen invasion remains limited. …”
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Urban Recreational Space Heat-Emotion Distribution and Matching Pattern Based on Machine Learning: A Case Study of Guangzhou City by Wang Fuyuan, Zhang Zhiyu, Xie Yuanjing, Yang Xinyi, Sun Miao

“…Spatially, this disconnect can be categorized into three distinct types: the "polarized" pattern in the central city, the "experience enhancement" pattern in the Huadu, Panyu, Baiyun, and Conghua Districts, and the "insufficient supply" pattern in the Zengcheng, Huangpu, and Nansha Districts. …”
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Regional patterns of genetic variants in expanded carrier screening: a next-generation sequencing pilot study in Fujian Province, China by Danhua Guo, Danhua Guo, Nani Zhou, Qianqian He, Qianqian He, Na Lin, Na Lin, Shuqiong He, Shuqiong He, Deqin He, Deqin He, Yifang Dai, Yifang Dai, Ying Li, Ying Li, Xuemei Chen, Xuemei Chen, Hailong Huang, Hailong Huang, Jia Jia, Hua Cao, Liangpu Xu, Liangpu Xu

“…The cumulative carrier rate for 28 genes was ≥1/100. Recurrent variants in GAA, GALT, CYP1B1, and MEFV were identified, exhibiting distinct regional patterns compared to previously reported variants in the Han Chinese population.ConclusionNGS-based ECS demonstrates significant potential for assessing the genetic burden of AR/XLR conditions and identifying ARCs in Fujian Province. …”
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Real-World Clinical Outcomes and Treatment Patterns Among Black and Non-Black Patients With Prostate Cancer Initiated on Apalutamide in a Urology Setting by Benjamin H. Lowentritt, Carmine Rossi, Erik Muser, Frederic Kinkead, Bronwyn Moore, Patrick Lefebvre, Dominic Pilon, Shawn Du

“…In patients with mCSPC, overall progression to castration resistance rates at 12 and 24 months were 20.9% and 33.5%, and overall CRFS rates were 76.2% and 62.0%, respectively. …”
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Expression patterns of TROP2 and Nectin-4 in oropharyngeal squamous cell carcinoma in relation to HPV status: potential biomarkers for targeted therapy by Charlotte Klasen, Hans N. C. Eckel, Nora Wuerdemann, Joseph Böckelmann, Karl Knipper, Malte Suchan, Kariem Sharaf, Shachi Jenny Sharma, Helen Abing, Arthur Charpentier, Julia Esser, Kevin Hansen, Marcel Mayer, Louis Jansen, Jens Peter Klußmann, Alexander Quaas, Su Ir Lyu

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Prevalence, antimicrobial susceptibility patterns, and associated risk factors of species in healthcare and community settings in Ethiopia: a systematic review and meta-analysis by Zigale Hibstu Teffera, Wubetu Yihunie Belay, Bantayehu Addis Tegegne, Abebe Dagne, Adane Adugna, Habtamu Belew, Yasabe Leykun, Samrawit Tefera, Bewket Mesganaw Shtie, Abebe Yenesew, Abateneh Melkamu, Gashaw Azanaw Amare, Desalegn Abebaw, Yibeltal Akelew, Mohammed Jemal, Baye Ashenef, Mamaru Getinet, Temesgen Baylie, Mihiretie Kiber, Mamaru Tilahun Afework, Tiruzer Hibistu, Kassaye Enchalew

“…Antimicrobial susceptibility tests identified cephalexin and co-trimoxazole as the most effective antibiotics (100% sensitivity each), while oxacillin, trimethoprim-sulfamethoxazole, and norfloxacin exhibited the highest resistance rates (85.71%, 80.00%, and 80.00%, respectively). …”
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Trends and pattern of contraceptive use among women attending a family planning clinic at a tertiary health facility in Ibadan, Nigeria by A. O. Atoyebi, S. O. Olaoye, M. A. Okunlola, M. E. Palamuleni, A. S. Adebowale

“…Abstract Background Despite consistent reporting of high fertility levels in Nigeria, contraceptive prevalence rates remain low. Information on the type of contraceptive uptake among women who visit family planning (FP) clinics is still sketchy in Ibadan. …”
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Bacterial profile and antimicrobial resistance patterns among pediatrics patients with suspected bloodstream infections in Ethiopia: a systematic review and meta-analysis by Bekele Sharew, Mihret Tilahun

“…Subgroup analyses revealed MDR rates of 81.9% in general wards, 78.35% in NICUs, 82.07% among children, and 78.86% among neonates. …”
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Mass spectrometry-based identification of 26 Pasteurella species and in vitro antimicrobial susceptibility pattern of isolates recovered from diseased domestic cats by Carolina A. Rodrigues, Marcelo F. Arabe Filho, Thais S. Bello, Fábio V.R. Portilho, Fernando J.P. Listoni, Fábio S. Possebon, Patrik Jr. L. Paz, Paulo C.L. Eliam, Márcio G. Ribeiro

“…Also, it highlights the need for the early diagnosis and therapy of feline pasteurellosis due to high mortality rates.…”
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Symptom Network Analysis and Unsupervised Clustering of Oncology Patients Identifies Drivers of Symptom Burden and Patient Subgroups With Distinct Symptom Patterns by Brandon H. Bergsneider, Terri S. Armstrong, Yvette P. Conley, Bruce Cooper, Marilyn Hammer, Jon D. Levine, Steven Paul, Christine Miaskowski, Orieta Celiku

“…In this study, computational approaches were used to unbiasedly characterize the heterogeneity of the symptom experience of oncology patients to elucidate symptom patterns and drivers of symptom burden. Methods Severity ratings for 32 symptoms on the Memorial Symptom Assessment Scale from 3088 oncology patients were analyzed. …”
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Prevalence, antimicrobial resistance pattern, and associated factors of Salmonella serovars among human-animal interfaces in the Amhara National Regional State, Ethiopia by Getachew Mengistu, Anwar Nuru, Baye Gelaw, Feleke Moges

“…Human isolates of Salmonella serovars exhibited high resistance rates to ampicillin (79.6%) and tetracycline (71.4%). …”
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Fertility Counseling Pattern over Time in Young Patients with Breast Cancer: A Retrospective Analysis at a Large Comprehensive Cancer Center by Caterina Barbieri, Ottavia Amato, Anna Chiara Cattelan, Loris Marin, Alessandra Andrisani, Carlo Saccardi, Tommaso Giarratano, Giovanni Faggioni, Elisabetta Di Liso, Carlo Alberto Giorgi, Eleonora Mioranza, Cristina Falci, Grazia Maria Vernaci, Roberto Tozzi, Valentina Guarneri, Maria Vittoria Dieci

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Sex-Specific Patterns and Predictors of Reverse Left Ventricular Remodeling and Outcomes in STEMI Patients with LVEF ≤ 50% After Successful Primary Angioplasty by Bogdan-Flaviu Buz, Sergiu-Florin Arnautu, Mirela-Cleopatra Tomescu, Minodora Andor, Simina Crisan, Dan Gaita, Cristina Vacarescu, Constantin-Tudor Luca, Cristian Mornos, Dragos Cozma, Diana-Aurora Arnăutu

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Treatment Patterns, Adverse Events, and Clinical Outcomes with Steroidal Mineralocorticoid Receptor Antagonists: A Retrospective Analysis of Administrative Claims Data (RELICS) by Richard EL, Desai NR, Willey VJ, Gay A, Scott C, Folkerts K, Pessina E, Singh R, Teng CC, Oberprieler NG

“…Patients with a higher comorbidity burden, such as those with both CKD and T2D rather than CKD alone, experienced worse outcomes.Conclusion: High rates of treatment discontinuation and subsequent restart were observed across all subgroups, implying fluctuating sMRA use. …”
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A retrospective study of the antimicrobial susceptibility patterns of Klebsiella pneumoniae isolated from urine samples over a decade in South India by Mahadevaiah Neelambike Sumana, Yogeesh D. Maheshwarappa, Kalyani G., Kalyani G., Rashmi P. Mahale, Sowmya G. S, Morubagal Raghavendra Rao, Ranjitha Shankaregowda, Vidyavathi B. Chitaragi, Deepashree R., Sujatha S. R., Neetha S. Murthy, Badveti Satyasai, Vasimalli Vinay Kumar, Supreeta R. Shettar

“…Of the 920 K. pneumoniae isolates, 385 (41.84%) were carbapenem-resistant (CRKP). Isolation rates were higher in males (n = 229, 59.48%) than females (n = 156, 40.52%), with a statistically significant p-value (<0.0001). …”
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Predictors and Patterns of Adherence to Mood Stabilizers in Patients with Bipolar Affective Disorder in a Tertiary Care Hospital in South India – A Retrospective Study by Rahma Nazar, Rahul Madhava Rao, Sharon Sankeshwar

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Antimicrobial Resistance Patterns and Serological Diversity of <i>Shigella</i> Species from Patient Isolates at University Teaching Hospital in Lusaka, Zambia by Mike Nundwe, Joseph Yamweka Chizimu, John Mwaba, Misheck Shawa, Rodrick S. Katete, Mable Mwale Mutengo, Ruth Nakazwe, Namwiinga R. Mulunda, Cephas Sialubanje, Mox Malama Kalumbi, Yamba Kaunda, Rapheal Chanda, Herman Chambaro, Harvey K. Kamboyi, Thoko Kapalamula, Steward Mudenda, Freeman W. Chabala, Bernard M. Hang’ombe, Roma Chilengi, Chie Nakajima, Yasuhiko Suzuki

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Patterns of Opportunistic Infections and Antiretroviral Therapy Efficacy in Newly Diagnosed Human Immunodeficiency Virus-1 Patients: A Descriptive Study in India by N Kisenjang, Sumit Arora, Pooja Sangwan, Imam D Khan, Charu Mohan, Anmol Sharma, Vikram Sharma, Ankit Rao, Aditya Puniyani, Shivani Sangwan, Alisha Sharma, Swati Jain, Anuradha Makkar, Preeti Badhan, H Vanalahruaii

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The expanded inframammary fold triangle: Improved results in large volume breast reductions by Karan Chopra, Kashyap Komarraju Tadisina, Alexandra Conde-Green, Devinder P Singh

“…However, complication rates in super obese patients or patients receiving large volume reductions are high, ranging from 35 to 78%. …”
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Bacterial etiology of urinary tract infections and their sensitivity patterns towards commonly used antibiotics in port Sudan City, Sudan: a retrospective study by Abdalla I.A Ibrahim, Hafeia A. Abdelgyoum, Noor S. Elfaki, Mohamed H. Elbadawi, Eyad Kashif

“…Conclusion Despite some high sensitivity rates, resistance to multiple antibiotic classes remains a concern, underscoring the need for continuous surveillance and localized treatment guidelines. …”
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