Diagnosis and management of endometrial hyperplasia: A UK national audit of adherence to national guidance 2012-2020. by Ian Henderson, Naomi Black, Hajra Khattak, UKARCOG Working Group Authors, Janesh K Gupta, Michael P Rimmer

“…By 2 years, follow-up to histological regression without hysterectomy increased from 38% (95% CI [33%, 43%]) to 52% (95% CI [47%, 58%]) for those with NEH (rate ratio (RR) 1.38, 95% CI [1.18, 1.63] p < 0.001). …”
Get full text

A cross-sectional study of evaluating cervical spondylotic myelopathy based on gait and plantar pressures by Xuhong Zhang, Zichuan Wu, Hanlin Song, Aochen Xu, Junbin Liu, Junzhe Sheng, Baifeng Sun, Min Qi, Chen Xu, Yang Liu

“…Gait parameters were obtained by capturing video of the patient while walking via a smartphone-based computer vision algorithm (using the OpenPose framework), and plantar pressure distributions were measured using wireless sensor-equipped insoles (sampling rate 50–100 Hz). Gender, age, and body mass index were employed as matching variables, resulting in 102 matched pairs. …”
Get full text

PREACT-digital: study protocol for a longitudinal, observational multicentre study on digital phenotypes of non-response to cognitive behavioural therapy for internalising disorder... by Christine Knaevelsrud, Sebastian Burchert, Till Langhammer, Leona Hammelrath, Annette Brose, Manuel Heinrich, Pavle Zagorscak

“…We collect passive data on heart rate, physical activity, sleep and location patterns. …”
Get full text

Guideline Utilization in Oncology: Addressing Barriers and Facilitators in Latin America and the Caribbean by Yanin Chavarri-Guerra, Luis Corrales, James D. Morgante, Henry Gomez, Alba Kihn-Alarcón, Rodrigo Munhoz, Els Dams

“…Descriptive statistics were used to analyze the data.RESULTSOf the 1,265 invited physicians, 140 responded (11% response rate). Most respondents reported frequent use of guidelines, with 47.9% using them often and 40.7% always. …”
Get full text

Identification of Yellow Pigmentation Genes in Brassica rapa ssp. pekinensis Using Br300 Microarray by Hee-Jeong Jung, Ranjith Kumar Manoharan, Jong-In Park, Mi-Young Chung, Jeongyeo Lee, Yong-Pyo Lim, Yoonkang Hur, Ill-Sup Nou

“…These results indicate that the yellow leaves accumulate high levels of both lutein and β-carotene due to stimulation of synthesis and that the degradation rate is inhibited. A large number of responsible genes as novel genes were specifically expressed in yellow inner leaves, suggesting the possible involvement in pigment synthesis. …”
Get full text

Non-invasive dual-brain stimulation facilitates social cooperation through enhancing interpersonal neural synchronization by Lifen Zheng, Chunming Lu

“…Moreover, compared to sham dual-brain tDCS, the active dual-brain tDCS significantly increased the rate of cooperative strategic behaviors as well as the dyadic economic gains. …”
Get full text

miR-276 and miR-182013-5p modulate insect metamorphosis and reproduction via dually regulating juvenile hormone acid methyltransferase by Jiasheng Song, Wanwan Li, Lulu Gao, Qiang Yan, Xinyan Zhang, Mingzhi Liu, Shutang Zhou

“…We found that Jhamt, a rate-limiting enzyme in JH biosynthesis, mirrors JH titer patterns in the migratory locust. …”
Get full text

Vegetation structure and soil organic carbon storage across northern forest-tundra ecotones in continuous permafrost by H. Travers-Smith, N.C. Coops, T.C. Lantz, M. Hamp, D. Ignace, M.A. Wulder, J. van der Sluijs

“…Between treeline types, we observed differences in C:N ratios and organic matter depth related to the rate of soil carbon turnover and SOC storage. Overall, SOC showed small positive relationships with tree stem density and average canopy height. …”
Get full text

Detecting Black-Box Model Probing Attacks Through Probability Scores by Yongzhi Wang, Ahsan Habib, Likhitha Reddy Kesara, Brahmarshi Jasti, Renjie Hu, Tejasv Singh

“…Compared with existing defense methods, our classifiers can reduce the Attack Success Rate (ASR) of the OARS-enhanced attacks from 93% to 1.78%. …”
Get full text

Expression of toxic shock syndrome toxin-1 gene of Staphylococcus aureus in milk: Proof of concept by Milijana Babić, Marija Pajić, Aleksandra Nikolić, Vlado Teodorović, Milorad Mirilović, Lazar Milojević, Branko Velebit

“…The results of experiments showed the dependence of the growth rate and consequent up-regulation of TSST-1 encoding gene on storage time-temperature and type of milk. …”
Get full text

Coupling Coordination Development Between Cultivated Land and Agricultural Water Use Efficiency in Arid Regions: A Case Study of the Turpan–Hami Basin by Yue Kong, Abdugheni Abliz, Dongping Guo, Xianhe Liu, Jialin Li, Buasi Nurahmat

“…A coupling coordination degree model was constructed to evaluate their coordinated development level, with spatial autocorrelation and other methods used to examine spatiotemporal patterns. Key findings include: (1) The overall utilization efficiency of both resources was relatively low, with mean values of 0.516 and 0.596, showing a fluctuating upward trend and significant spatial heterogeneity; (2) The mean coupling coordination degree (CCD) ranked as follows: Barkol Kazakh Autonomous County (0.587) > Yiwu County (0.563) > Gaochang District (0.494) > Shanshan County (0.437) > Tuokexun County (0.417) > Yizhou District (0.342), with an annual growth rate of 4.6%; (3) Regional disparities were dominated by intra-regional differences (42.0%), followed by transvariation density (30.64%). …”
Get full text

Design of a Methodology to Evaluate the Energy Flexibility of Residential Consumers to Enhance Household Demand Side Management: The Case of a Spanish Municipal Network by Caterina Lamanna, Andrés Ondó Oná-Ayécaba, Lina Montuori, Manuel Alcázar-Ortega, Javier Rodríguez-García

“…Climate change and global warming are causing growing environmental concerns, prompting many countries to increase investments in renewable energies. The high growth rate of renewables in the energy systems brings significant intermittency challenges. …”
Get full text

Genome-wide analysis of the KCS gene family in Medicago truncatula and their expression profile under various abiotic stress by Peng Lv, Jiaqi Lv, Yawen Zhan, Ning Wang, Xinyan Zhao, Qi Sha, Wen Zhou, Yujie Gong, Jing Yang, Hang Zhou, Pengfei Chu, Yongwang Sun

“…Abstract Very long-chain fatty acids (VLCFAs) are indispensable constituents of cuticular wax and exert pivotal functions in regulating plant growth, development and response to stress. β-Ketoacyl-CoA synthase (KCS) represents the rate-limiting enzyme for the biosynthesis of VLCFAs. …”
Get full text

Efficacy of human heparin-binding EGF-like growth factor in healing experimental chemical burns by L. M. Dronko, T. M. Lutsenko, O. I. Golembiovska, T. Yu. Trokhymchuk, M. A. Arkhypova, V. A. Dibrova, Yu. V. Dibrova, S. L. Rybalko, S. A. Myakushko, A. A. Siromolot, O. Yu. Galkin

“…The preparations (100 μl, 1.5 mg of rhHB-EGF) were applied to burn wounds daily for 5 days. Wound area, healing rate and histological patterns of skin samples were estimated. …”
Get full text

Assessment of the functional state of left heart in patients with chronic heart failure with preserved ejection fraction by D. V. Vdovenko, R. A. Libis

“…Patients with CHF-PEF had reduced global longitudinal strain (GLS) -16,56±2,61% and GLS rate (GLSR) -0,75±0,11s-1 of the left ventricle and reduced segmental strain and strain rate in basal anteroseptal (-14,72±2,54% and -0,76±0,05s-1) and basal anterolateral (-14,27±3,29% and -0,79±0,12s-1) segments. …”
Get full text

Clinical benefit of tafasitamab plus lenalidomide in relapsed or refractory diffuse large Bcell lymphoma: real-world data from the EarlyMIND study by Gabriel Brisou, Jérôme Paillassa, Sophie Bernard, Olivier Tournilhac, Luc-Matthieu Fornecker, Frédéric Maloisel, Lauris Gastaud, Eric Durot, Adrian Tempescul, Thorsten Braun, Vadim Ivanov, Brieuc Cherel, Caroline Serrier, Jeremy Delage, Abderrazak El Yamani, Baptiste Delapierre, Laure Lebras, Elsa Lestang, Camille Villesuzanne, Philippe Agape, Guillaume Escure, Ludovic Fouillet, Christophe Nicol, Gaëlle Olivier, Anthony Levy, Anne-Sophie Le Bris, Ophélie Cassuto, Laura Jacquemelle, Corinne Haioun, Charles Herbaux

“…Approval was based on the L-MIND study, which demonstrated a 57.5% overall response rate (ORR), 41.3% complete response (CR) rate, 12.1 months median progression-free survival (PFS), and 33.5 months median overall survival (OS) at five years. …”
Get full text

A Comparative Analysis of Genetic Diversity and Structure in Jaguars (Panthera onca), Pumas (Puma concolor), and Ocelots (Leopardus pardalis) in Fragmented Landscapes of a Critical... by Claudia Wultsch, Lisette P Waits, Marcella J Kelly

“…Although levels of genetic diversity and gene flow were still fairly high, we detected evidence of fine-scale genetic subdivision, indicating that levels of genetic connectivity for wild felids in Belize are likely to decrease if habitat loss and fragmentation continue at the current rate. Our study demonstrates the value of understanding fine-scale patterns of gene flow in multiple co-occurring felid species of conservation concern, which is vital for wildlife movement corridor planning and prioritizing future conservation and management efforts within human-impacted landscapes.…”
Get full text

Scene Semantic Recognition Based on Modified Fuzzy C-Mean and Maximum Entropy Using Object-to-Object Relations by Ahmad Jalal, Abrar Ahmed, Adnan Ahmed Rafique, Kibum Kim

“…During experimental evaluation, our proposed system illustrated a remarkable mean accuracy rate of 90.07&#x0025; over the MSRC dataset and 89.26&#x0025; over the Caltech 101 for object recognition, and 93.53&#x0025; over the Pascal-VOC12 dataset for scene recognition, respectively. …”
Get full text

A multimodal approach for ADHD with coexisting ASD detection for children by Jungpil Shin, Sota Konnai, Md. Maniruzzaman, Yoichi Tomioka, Yong Seok Hwang, Akiko Megumi, Akira Yasumura

“…This study proposes a novel approach that increase the detection rate and provides new insights for further research.…”
Get full text

Conventional synthetic disease-modifying antirheumatic drug use by race/ethnicity and factors associated with initiating biologics in Malaysian patients with rheumatoid arthritis by Suad Mohammed, Lydia Say Lee Pok, Ying Chew Tee, Fariz Yahya

“…Disease activity score 28–erythrocyte sedimentation rate improved at 3 months post-csDMARD treatment for all races (P < 0.001). …”
Get full text