Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Two gastrointestinal events occurred, including one Grade 3 diarrhea treated with GCs. The overall GC usage rate was 31.7% (13/41), with 76.9% administered for Grade ≥3 irAEs. …”
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Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Disease burden was high and decreasing in low SDI regions, but low and stable in high SDI regions. The Age-standardized rate(ASR)-Deaths correlated negatively with SDI. …”
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Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
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Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
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Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Results Bacterial pathogens were isolated from 33 patients, representing an isolation rate of 22.1% (95% CI: 16.2–29.6%). Gram-negative bacteria (GNB) accounted for the majority of the isolates, 25/33 (75.8%), with Escherichia coli, 6/25 (24%) being the predominant species. …”
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Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…Therefore, in this study, corrosion void formation and migration mechanism on a newly designed alloy (Ni–28Cr–13Al–5W-0.06B-0.005C) was investigated and the corrosion rate of the alloy was compared with that of Ni–20Cr alloy under simulated municipal solid waste (MSW) incineration conditions at 600 °C. …”
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Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection by Qingze Gu, Kevin Yuan, Jia Wei, Chang Ho Yoon, Anders Skyrud Danielsen, Augustine Luk, David W. Eyre, A. Sarah Walker

“…CRP percentile changes were modestly associated with subsequent antibiotic adjustments; in particular, suboptimal recovery, indicated by an increase in CRP centiles, was associated with a higher rate of antibiotic escalation (16.5% vs. 10.7% in expected recovery) and, conversely, faster than expected recovery in CRP was associated with de-escalation (23.6% vs. 17.2%). …”
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Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches by Isabella D’Ambra, Isabella D’Ambra, Simona Saviano, Maria Assunta Ambrosio, Vincenzo Botte, Daniele Iudicone, Maria Grazia Mazzocchi, Louise Merquiol, Louise Merquiol, Louise Merquiol, Daniela Cianelli

“…SIs were determined in scyphomedusae and their potential planktonic prey collected at the Long Term Research site MareChiara (LTER-MC) during the outbreaks and during the previous three weeks, to account for the turnover rate of medusae. Numerical simulations were performed using a particle tracking model forced by a Regional Ocean Modeling System (ROMS) developed for the GoN. …”
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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod... by Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S. Lee

“…The in vivo results revealed that the day-5 mortality rate and creatinine levels at days 2 and 5 were significantly greater in group 2 than in groups 1 and 5 ( P = 0.01), whereas the kidney injury score and inflammatory cell infiltration in the kidney were highest in group 2, lowest in group 1, and significantly greater in groups 3 and 4 than in group 5; however, there was no difference between groups 3 and 4 (all P < 0.0001). …”
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A Case Study Analysis of Separation Anxiety in the Effect of the Maternal and Paternal Role on Separation Anxiety in Early Childhood by Elena Drazheva

“…The aim is to understand how different patterns of attachment and family dynamics influence the intensity of anxiety reactions. …”
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Effect of storage temperature on freshness of silver carp (Hypophthalmichthys molitrix) by YAO Yan-jia, ZHANG Jin-jie, GU Wei-gang, JI Rong, HU Ya-qin

“…Moreover, the results show that frozen storage is an effective method to slow down the rate of freshness decrease of silver carps.…”
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Internet of things in healthcare monitoring to enhance acquisition performance of respiratory disorder sensors by Leonardo Juan Ramírez López, Arturo Rodriguez Garcia, Gabriel Puerta Aponte

“…The proposed model is validated on the measurement and monitoring of oxygen saturation, heart rate, and body temperature in patients with respiratory disorders. …”
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Association of psychosocial factors and biological pathways identified from rare-variant analysis with longitudinal trajectories of treatment response in major depressive disorder by Haiping Tang, Yan Xia, Chenjie Gao, Yufan Cai, Yongqi Shao, Wenji Chen, Yonggui Yuan, Chunyu Liu, Zhijun Zhang, Zhi Xu

“…Treatment response trajectories were identified through cluster analysis using normalized score change ratios from the 17-item Hamilton Rating Scale for Depression (HAMD-17) at baseline and weeks 2, 4, 6, and 8. …”
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Neurobehavioral mechanisms of fear and anxiety in multiple sclerosis by Lil Meyer-Arndt, Rebekka Rust, Judith Bellmann-Strobl, Tanja Schmitz-Hübsch, Lajos Marko, Sofia Forslund, Michael Scheel, Stefan M. Gold, Stefan Hetzer, Friedemann Paul, Martin Weygandt

“…The fact that a machine learning model trained to associate fMRI fear response patterns with fear ratings in HPs predicts fear ratings from fMRI data across MS groups using an MVPA cross-decoding approach suggests that generic fear processing mechanisms substantially contribute to anxiety in MS.…”
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Catheter-associated Urinary Tract Infections in a trauma care facility in India: trend over ten years by Aparna Ningombam, Arpan Kumar Thakur, Ashish Kumar Srivastava, Sharin Varma, Madhavi Kirti, M. Nizam Ahmed, Vanlal Tluanpuii, Kapil Dev Soni, Richa Aggarwal, Gyanendra Pal Singh, Ashish Bindra, Navdeep Sokhal, Keshav Goyal, Kamran Farooque, Purva Mathur

“…Among 546 patients, 577 episodes of CAUTI were recorded, giving a CAUTI rate of 7.4/1,000 catheter days. The average length of stay (LOS) of patients was 19.9 days. …”
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Investigation of Dual-Vortical-Flow Hybrid Rocket Engine without Flame Holding Mechanism by A. Lai, T.-H. Chou, S.-S. Wei, J.-W. Lin, J.-S. Wu, Y.-S. Chen

“…This engine was numerically investigated using a CFD tool that can handle reacting flow with finite-rate chemistry and coupled with the real-fluid model. …”
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Comparison of growth, photosynthetic, and chlorophyll fluorescence characteristics of different native cultivars in Castanea henryi by XU Bin, WU Jingyi, WU Jianfeng, SU Xinyu, ZHAO Junru, ZHU Zhoujun, LI Jianxin

“…The target leaves were marked and subsequently photoinduced at a light intensity of 1200 μmol·m-2·s-1 for at least 20 minutes until stabilization of the net photosynthetic rate (Pn). The light-response curves were fitted through a rectangular hyperbolic correction model, with parameters recorded including maximum net photosynthetic rate (Pnmax), light saturation point (LSP), apparent quantum efficiency (AQY), light compensation point (LCP), and dark respiration rate (Rd). …”
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Hydrodynamic Performance and Cavitation Analysis in Bottom Outlets of Dam Using CFD Modelling by Omid Aminoroayaie Yamini, S. Hooman Mousavi, M. R. Kavianpour, Ramin Safari Ghaleh

“…Bottom outlets are significant structures of dams, which are responsible for controlling the flow rate, operation, or removal of reservoir sedimentation. …”
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STRATEGI BRANDING DAN KONSEP PUBLIKASI BERBASIS LOCAL TOURISM DI ERA 4.0 (Studi kasus media sosial dan peran Desain Komunikasi visual) by Eko Darmawanto, Kukuh Dwi Wijanarko

“…Local tourism branding and publication strategies are influenced by engagement from the psychological model of one touch flayer of social media users related to the happynest side factor that affects the pattern of attractive content with a high response rate and saddnes side factor which is empathetic with a low response rate.…”
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