Assessing patient-reported outcomes (PROs) in paediatric oncology research: Which PRO would a pro pick, if a pro was picking PROs? by Ameeta Retzer, Sarah Al-Jilaihawi, Shivani Bailey, Vickie Buenger, Sarah Damery, Anne-Sophie Darlington, Manuel Diezi, John Devin Peipert, Jessica Roydhouse, Bryce B. Reeve

“…The choice of PRO depends on the intended application and associated research questions, and structuring a rationale for the use of PRO data is key to deciding upon a PRO strategy. Rates of PRO use in paediatric oncology research remain low though the general use of PROs in clinical trials has been gradually increasing. …”
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Groundwater ammonia-oxidizing bacteria distribution and the correlations between the distribution and environmental factors around livestock lagoons by REN Juan, ZHANG Lei, ZENG Lingzao, WU Laosheng, SHI Jiachun

“…In water nitrate cycle, micro-organisms play a significant role. The first and rate limiting step of nitrification is ammoxidation, and the functional gene is ammonia monooxygenase, which existed in ammonia-oxidizing bacteria and ammonia-oxidizing archaea.However, the factors affecting ammonia-oxidizing bacteria distribution pattern in groundwater and the influence mode are still not clear enough. …”
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Content-Based Brain Magnetic Resonance Image Retrieval and Classification With the Proposed Deep Learning and Tissue-Based System by Bedriye Dogan, Hursit Burak Mutlu, Muhammed Yildirim, Sercan Yalcin, Serpil Aslan, Niranjana Sampathila, Ozal Yildirim, Edward J. Ciaccio, Ru-San Tan, U. Rajendra Acharya

“…Notably, existing machine architectures already published in the literature have struggled to achieve comparable success rates in discerning such closely related yet distinct disease groups. …”
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A Long-Term Overview of Elasmobranch Fisheries in an Oceanic Archipelago: A Case Study of the Madeira Archipelago by Mafalda Freitas, Filipa Pinho-Duarte, Madalena Gaspar, Pedro Ideia, João Delgado, Sara C. Cerqueira, Ricardo Sousa

“…Management measures currently in place need to be updated and ought to be based on studies on the type and size of hooks for each fishery, to ultimately infer about species-specific survival rates, as well as the fishing gears’ soak time. Moreover, studies on the enhancement of food supply through fisheries discards are still missing, even though it is highly likely that this input may alter the dynamics of marine food webs.…”
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The large and central Caligo martia eyespot may reduce fatal attacks by birds: a case study supports the deflection hypothesis in nature by Iserhard, Cristiano Agra, Malta, Shimene, Penz, Carla, Fraga, Brenda Barbon, Costa, Camila Abel, Schwantz, Taiane, Bordin, Kauane Maiara

“…Eyespots did not appear to reduce attack rates, suggesting that local bird species were not intimidated. …”
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Business Intelligence Model of Regional Hospitals using HGOD Discovery by Hengki Hengki, Rahmat Gernowo, Oky Dwi Nurhayati

“…Based on data from the Regional General Hospital in the Bangka Belitung Islands province, the Gross Death Rate (GDR) is the general death rate for every 1000 patients discharged of 108,430 compared to the health department standard of <45. …”
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Development of a Quadruplex RT-qPCR Assay for Rapid Detection and Differentiation of PRRSV-2 and Its Predominant Genetic Sublineages in China by Guishan Ye, Siyu Xiong, Zhipeng Su, Guosheng Chen, Siyuan Liu, Zixuan Wang, Huanchun Chen, Anding Zhang

“…Field application using 938 samples from Guangxi A and B farms revealed NADC30-like PRRSV wild-type strains at positivity rates of 13.44% and 3.53%, respectively. Positive samples selected for sequencing were further confirmed using ORF5-based phylogenetic analysis and NSP2 deletion pattern comparison, which aligned with RT-qPCR detection results. …”
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Time Course of Changes in the Level of Procalcitonin in the Development of Nosocomial Pneumonia in Victims with Severe Concomitant Injury in an Intensive Care Unit by A. K. Shabanov, M. Sh. Khubutia, G. V. Bulava, N. V., Beloborodova, A. N. Kuzovlev, O. A. Grebenchikov, D. A. Kosolapov, M. I. Shpitonkov

“…The posttraumatic period in victims with severe concomitant injury is frequently complicated by nosocomial pneumonia, resulting in high mortality rates and longer time and increased cost of treatment in intensive care unit unit patients. …”
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Volumetric evolution of supraglacial lakes in southwestern Greenland using ICESat-2 and Sentinel-2 by T. Feng, T. Feng, X. Ma, X. Ma, X. Liu, X. Liu, X. Liu

“…Additionally, according to the evolution characteristics of SGLs at different elevations, SGLs above 800 m exhibit a similar evolution pattern. A temporal discrepancy in maximum values for both mean area and mean depth implies differential rates of SGL development in the horizontal and vertical dimensions. …”
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Evaluation of urea loaded nano clay biopolymer composites and nitrification inhibitors on nitrogen use efficiency under maize-wheat cropping system by Premlata Meena, K. M. Manjaiah, Kapil Atmaram Chobhe, Vinod Kumar Sharma, Hanuman Singh Jatav, Mamta, Ajit Kumar Meena

“…The recommended amount of N was 150 kg ha−1and applied at the rates of 0, 50, 75, and 100% by using urea and NCBPC (loaded with urea and nitrification inhibitors) in the three equal split doses at 45, 60, and 90 DAS (days after sowing). …”
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Does Seasonality Affect Peptic Ulcer Perforation? A Single-Center Retrospective Study by Iva Krajnović, Zenon Pogorelić, Iva Perić, Marija Ćavar, Matija Borić

“…Previous studies have suggested a seasonal pattern in the occurrence of symptomatic perforated peptic ulcers. …”
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Double fluorescence-guided surgery with 5-ALA and fluorescein sodium in grade 2 and grade 3 adult-type diffuse gliomas: retrospective analysis of 112 cases by Andrea Bianconi, Marta Bonada, Pietro Zeppa, Francesco Bruno, Pietro La Cava, Flavio Panico, Roberta Rudà, Antonio Melcarne, Diego Garbossa, Fabio Cofano

“…Fluorescence positive rate and pattern have been reported both for 5-ALA and for fluoresceine. …”
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Solution of an Uncertain EPQ Model Using the Neutrosophic Differential Equation Approach by Mostafijur Rahaman, Rakibul Haque, Soheil Salahshour, Anna Sobczak, Fariba Azizzadeh, Shariful Alam, Sankar Prasad Mondal

“…Time is a very crucial factor in controlling demand patterns for certain products. In manufacturing processes, the production rate must be regulated according to the demand pattern and available stock as a part of effective lot size management policies. …”
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Dynamic gas supply mechanism and theoretical production modes of free gas-rich deep coal reservoirs by Shida CHEN, Taiyuan ZHANG, Dazhen TANG, Hao XU, Shu TAO, Song LI, Shuling TANG

“…Furthermore, the first priority for commercial production capacity construction of deep CBM is determining rational production capacity targets and required well-controlled areas for varying deep geological units and synergistically optimizing well completion methods, well pattern density, fracturing parameters, production allocation rates, and production cycles under the guidance of geological and engineering integration.…”
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Experimental study on seepage characteristics model of tunnel lining based on infrared imaging by Zhijian Wu, Hua Wu, Yichen Peng, Renjie Song, Yimin Wu, Haiping Wu, Guangzheng Zhuang

“…The results show that: (1) Geometric characteristics of seepage areas for various crack types were systematically summarized, where crack patterns and their positions determine the geometric features of seepage regions; (2) Seepage areas of all crack types increase with flow rate, and different crack morphologies exhibit distinct susceptibility to flow rate at varied positions; (3) The centroid distance curve of the seepage core area derived from isothermal maps enables rapid identification of crack morphologies and their positions within the tunnel by analyzing curve patterns. …”
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Characterization of a Novel 2018 Influenza Virus Outbreak on the Yucatan Peninsula, Mexico, in the Summer by Lumumba Arriaga-Nieto, David Alejandro Cabrera-Gaytán, Alfonso Vallejos-Parás, Porfirio Felipe Hernández-Bautista, Clara Esperanza Santacruz-Tinoco, Julio Elías Alvarado-Yaah, Yu-Mei Anguiano-Hernández, Bernardo Martínez-Miguel, María Erandhí Prieto-Torres, Concepción Grajales-Muñiz, Nancy Sandoval-Gutiérrez, Horacia Celina Velarde-Scull

“…Demographics, influenza positivity, seasonality and case fatality rates were recorded. We used odds ratios to compare outpatients who were confirmed by laboratory tests to be positive with those who were confirmed to be negative. …”
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Air-for-water substitution in characterizing lake heatwaves in the middle and lower reaches of the Yangtze River Basin by Zihan Zhu, Wei Wang, Heng Lyu, Bo Wang, Zhiwen Wen, Qiuxiang Jin

“…But the difference in long-term change rates between two heatwaves exhibits no discernible spatial pattern. …”
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Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study by Carlo Mümmler, MD, Alexandra Lenoir, MD, Jeremias Götschke, MD, Michael Gerckens, MD, Merle Kaiser, MD, Moritz Kayser, MD, Nora Drick, MD, Hendrik Suhling, MD, Leonie Biener, MD, Carmen Pizarro, MD, Dirk Skowasch, MD, Nikolaus Kneidinger, MD, PhD, Jürgen Behr, MD, Katrin Milger, MD

“…Data on asthma control, medication, lung function, and annualized exacerbation rates were collected at baseline and 3, 12, and 36 months after initiation of dupilumab therapy. …”
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Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer by Wenyi Yan, Yujing Xuan, Ruimin Wang, Ziyan Huan, Yu Guo, Huilin Dun, Lihua Xu, Ruxia Han, Xianlei Sun, Lingling Si, Nicholas Robert Lemoine, Yaohe Wang, Pengju Wang

“…The synergistic effects of VVL-GL7 and the PD-1 blockade further improved therapeutic outcomes, resulting in significantly higher tumor remission rates compared to monotherapy and achieving complete tumor regression in pancreatic cancer models. …”
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Development technologies and models of different types of gas reservoirs in Ordos Basin, NW China by Ailin JIA, Dewei MENG, Guoting WANG, Guang JI, Zhi GUO, Naichao FENG, Ruohan LIU, Suqi HUANG, Shuai ZHENG, Tong XU

“…Four key directions of future research and technological breakthroughs are proposed: (1) Utilizing dual-porosity (fracture-matrix) modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones, supporting well pattern optimization and production enhancement of existing wells. (2) Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata, enhancing drilling success rates in low-permeability sandstone reservoirs. (3) Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally, achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs, and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization. (4) Further strengthening the evaluation of deep coal-rock gas in terms of resource potential, well type and pattern, reservoir stimulation, single-well performance, and economic viability.…”
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