Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…Multiple myeloma (MM) is the second most prevalent hematologic malignancy characterized by a high synthesis rate of disulfide bond-rich proteins and chronic oxidative stress. …”
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Sustainability and energy self-sufficiency; overcoming the barriers by Rania Abdel Galil

“…Renewable energy technologies are viewed as radical innovations which necessitate substantial changes in production and consumption patterns, hence often met with resistance from both institutions and individuals. …”
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Discovery and molecular identification of a new orthophasmavirus in the Asian citrus psyllid (Diaphorina citri) by Song Zhang, Song Zhang, Jing Chen, Jing Chen, Luqin Liu, Luqin Liu, Zhipeng Xie, Zhipeng Xie, Jiamei Liang, Jiamei Liang, Fulin Yan, Fulin Yan, Yaqin Song, Xuefeng Wang, Xuefeng Wang, Changyong Zhou, Changyong Zhou, Mengji Cao, Mengji Cao, Jinxiang Liu, Jinxiang Liu

“…To investigate viral transmission patterns, progeny were obtained from mated infected ACP parents and used to feed on host plants. …”
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Widespread geographic distribution of filarioid nematodes in caribou (Rangifer tarandus sspp.) in Canada by Aparna Mariyam Thomas, Guilherme G. Verocai, John Soghigian, Fabien Mavrot, Naima Jutha, Jan Adamczewski, Tracy Davison, Gwen Duytschaever, Arthur Fernandes, Allicia Kelly, Matthew R. Kulpa, Eve Lamontagne, Lisa-Marie Leclerc, Sara McCarthy, Ashley McLaren, Amanda D. Melin, Susan J. Kutz

“…The Arctic is currently experiencing an unprecedented rate of climate change, including warming temperatures and altered patterns of precipitation. …”
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Release of Zinc, Manganese and Magnesium from Mg-Zn-Mn-Al-LDH: Effect of Malic Acid and Divalent to Trivalent Cation Ratios in Mineral Structure by Z. Movahedi Rad, M. Hamidpour

“…The X-ray diffraction patterns of LDH (3:1) and LDH (4:1) samples showed the existence of strong and sharp peaks for 003 and 006 plates. …”
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Mechanism of atrazine migration and diffusion control in soil by clay matrix composites by Xiangyu Wang, Qiang Fu, Tianxiao Li, Renjie Hou, Mo Li, Dong Liu, Fanying Kong, Mingxuan Liu, Shuqi Dong

“…In this study, three major problems of soil structure optimization, competitive adsorption enhancement and quantification of migration patterns in FC environments were solved through the preparation of clay-based composites (Sep/BC) combined with soil column simulation tests and isothermal adsorption tests. …”
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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites by Tingwen He, Tingwen He, Tingwen He, Xiaolong Yuan, Liangjun Xiao, Tanggeran Hu, Yi Wang, Xiaolei Zhao, Xiaolei Zhao, Xiaolei Zhao, Lu Li, Lu Li, Chengbo Peng, Chengbo Peng, Chengbo Peng, Hongling Zhang, Hongling Zhang, Hongling Zhang, Yuan Zheng, Yuan Zheng, Yuan Zheng, Yuan Zheng

“…This study compared the metabolite profiles and gene expression patterns of the fruiting bodies of T. gaoligongensis with those of three types of cultivated mycelia. …”
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The Gaseous Blowout of the 30 Doradus Starburst Region in the LMC by Suraj Poudel, April Horton, Jo Vazquez, Kathleen A. Barger, Frances H. Cashman, Andrew J. Fox, Nicolas Lehner, Scott Lucchini, Dhanesh Krishnarao, N. M. McClure-Griffiths, Elena D’Onghia, Jason Tumlinson, Ananya Goon Tuli, Lauren Sdun, Stone Gebhart, Katherine Anthony, Bryce Cole, Jacco Th. van Loon, Julia Roman-Duval, Yik Ki Ma, Callum Lynn, Min-Young Lee, Denis Leahy

“…The metallicities and dust depletion patterns of the high-velocity absorbers at v _LSR  ≈ +120 km s ^−1 can be explained by either a foreground Milky Way (MW) halo cloud or an outflow from the LMC. …”
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Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya by Edward K. Githinji, Lucy W. Irungu, Paul N. Ndegwa, Maxwell G. Machani, Richard O. Amito, Brigid J. Kemei, Paul N. Murima, Geoffrey M. Ombui, Antony K. Wanjoya, Charles M. Mbogo, Evan M. Mathenge

“…The study is aimed at determining species composition, levels of insecticide resistance, and knockdown patterns in Anopheles gambiae sensu lato in areas with and areas without insecticide resistance in Teso North and Teso South subcounties, Western Kenya. …”
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Estimation of long-term gridded cloud radiative kernel and radiative effects based on cloud fraction by X. Liu, T. He, Q. Wang, X. Xiao, Y. Ma, Y. Wang, S. Luo, L. Du, Z. Wu, Z. Wu

“…The GCF-CRKs exhibit similar signs and patterns and enhanced stability compared to existing kernels. …”
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Maternal asthma and newborn DNA methylation by Casper-Emil Tingskov Pedersen, Thanh T. Hoang, Jianping Jin, Anna Starnawska, Raquel Granell, Hannah R. Elliott, Anke Huels, Heather J. Zar, Dan J. Stein, Yining Zhang, Herman T. den Dekker, Liesbeth Duijts, Janine F. Felix, Júlia Sangüesa, Mariona Bustamante, Maribel Casas, Martine Vrijheid, Latha Kadalayil, Faisal I. Rezwan, Hasan Arshad, John W. Holloway, Stefan Röder, Ana C. Zenclussen, Gunda Herberth, Nicklas Heine Staunstrup, Henriette Thisted Horsdal, Jonathan Mill, Eilis Hannon, iPSYCH-MINERvA Group, Isabella Annesi-Maesano, Giancarlo Pesce, Nour Baïz, Barbara Heude, Sahra Hosseinian-Mohazzab, Carrie V. Breton, Sophia Harlid, Justin Harbs, Magnus Domellof, Christina West, Edwina Yeung, Xuehuo Zeng, Wenche Nystad, Siri E. Håberg, Maria C. Magnus, Diana Schendel, Stephanie J. London, Klaus Bønnelykke

“…Abstract Background Prenatal exposure to maternal asthma may influence DNA methylation patterns in offspring, potentially affecting their susceptibility to later diseases including asthma. …”
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Lipid-lowering statins and polyphenol-based supplementation: a scoping review on drug-food interaction potential by Rita Costa, Rita Costa, Rita Costa, Rita Costa, Rita Costa, Carolina Ferreira, Carolina Ferreira, Carolina Ferreira, André Alves, André Alves, André Alves, Sara Nunes, Sara Nunes, Sara Nunes, Sara Nunes, Sara Nunes, Flávio Reis, Flávio Reis, Flávio Reis, João Malva, João Malva, João Malva, Sofia Viana, Sofia Viana, Sofia Viana, Sofia Viana, Sofia Viana

“…BackgroundLifestyle modifications, particularly the adoption of healthy dietary patterns such as the Mediterranean Diet (MedDiet), are foundational in any treatment plan, including for patients prescribed first-line statin therapy for hypercholesterolemia. …”
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Risk of Incidence and Lethality by Etiology of Severe Acute Respiratory Syndrome in Hospitalized Children Under 1 Year of Age in Brazil in 2024: A Cross-Sectional Study by Tamires de Nazaré Soares, Natasha Cristina Oliveira Andrade, Suziane do Socorro dos Santos, Marcela Raíssa Asevedo Dergan, Karina Faine Freitas Takeda, Jully Greyce Freitas de Paula Ramalho, Luany Rafaele da Conceição Cruz, Perla Katheleen Valente Corrêa, Marli de Oliveira Almeida, Joyce dos Santos Freitas, Wilker Alves Silva, Marcos Jessé Abrahão Silva, Daniele Melo Sardinha, Luana Nepomuceno Gondim Costa Lima

“…Distribution by final classification and epidemiological week (EW) was analyzed; the incidence rate by Federative Unit (FU) (cases/100,000 < 1 year) with risk classification (Low/Moderate/High) was assessed; and, for cases with positive viral RT-PCR, the etiological frequency and virus-specific lethality rate (deaths/total cases of etiology ×100), also with risk classification, were extracted. …”
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Genetic evolution, epidemic trends, and recombination dynamics of PRRSV-1 in China by Chengzhen Weng, Chengzhen Weng, Chengzhen Weng, Xinxin Huang, Xinxin Huang, Xinxin Huang, Zhian Chen, Zhian Chen, Minjia He, Minjia He, Minjia He, Beiwen Zhang, Beiwen Zhang, Beiwen Zhang, Hongxi Li, Hongxi Li, Hongxi Li, Jingrui Xie, Jingrui Xie, Meichun Chen, Meichun Chen, Meichun Chen, Longxin Qiu, Longxin Qiu, Xiaobing Li, Xiaobing Li, Chong Cao, Chong Cao, Hongbo Chen, Hongbo Chen

“…This study systematically investigated the epidemiological patterns, genetic evolution, recombination dynamics, GP5 genetic diversity, and N-glycosylation variants of PRRSV-1 strains circulating in China. …”
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Silent Revolution in Research for Sustainability by Bruce Alder

“…A variety of new arrangements have come into existence that promote international collaboration, including Horizon 2020 with its emphasis on societal challenges, the Bill &amp; Melinda Gates Foundation which has inspired a family of grand challenges funds on health and development, and the Future Earth joint program of research for global sustainability. …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Young people are experiencing increasing levels of anxiety, depression, and loneliness at an alarming rate. Serious damage to emotional health stems from the pervasive information overload and social envy people experience through their constant online connection 3. …”
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Shear Strength Characteristics of Soft Soil in Nansha District of Guangzhou by WANG Wei-qi, LIAN Chang-jiang, LI Jian-ping, CHEN Zhi-yong, CHENG Dong-hai, CAI Wei-long, TANG Kai, LI Chao

“…Certain anomalies and unconventional patterns are observed in the dataset, including the opposite variation trends in the consolidated quick shear strength of both silt and silty soil with increasing depth, as well as the difference in the rate of strength change for silt at depths of 10 m≤h&lt;20 m under consolidated quick shear compared to direct shear conditions. …”
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Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorderResearch in context by Stephen Joza, Aline Delva, Christina Tremblay, Andrew Vo, Marie Filiatrault, Max Tweedale, Jean-François Gagnon, Ronald B. Postuma, Alain Dagher, Johannes Klein, Michele Hu, Petr Dusek, Stanislav Marecek, Zsoka Varga, John-Paul Taylor, John T. O'Brien, Michael Firbank, Alan Thomas, Paul C. Donaghy, Stéphane Lehéricy, Marie Vidailhet, Jean-Christophe Corvol, ICEBERG Study Group, Richard Camicioli, Howard Chertkow, Simon Lewis, Elie Matar, Kaylena A. Ehgoetz Martens, Lachlan Churchill, Michael Sommerauer, Sinah Röttgen, Per Borghammer, Karoline Knudsen, Allan K. Hansen, Dario Arnaldi, Beatrice Orso, Pietro Mattioli, Luca Roccatagliata, Oury Monchi, Shady Rahayel, Isabelle Arnulf, Samir Bekadar, Eve Benchetrit, Alexis Brice, Vanessa Brochard, Alizé Chalançon, Benoit Colsch, Florence Cormier-Dequaire, Jean-Christophe Corvol, Virginie Czernecki, Bertrand Degos, Cécile Delorme, Pauline Dodet, Carole Dongmo-Kenfack, Marie-Odile Habert, Farid Ichou, Jonas Ihle, Cécile Galléa, Rahul Gaurav, Marie-Alexandrine Glachant, Manon Gomes, David Grabli, Elodie Hainque, Laetitia Jeancolas, Christelle Laganot, Stéphane Lehéricy, Suzanne Lesage, Smaranda Leu-Semenescu, Richard Levy, Valentine Maheo, Graziella Mangone, Louise Laure Mariani, Aurelie Méneret, Poornima Menon, Fanny Mochel, Vincent Perlbarg, Dijana Petrovska, Fanny Pineau, Nadya Pyatigorskaya, Sophie Rivaud-Pechoux, Emmanuel Roze, Sara Sambin, Julie Socha, Arthur Tenenhaus, Romain Valabregue, Marie Vidailhet, Lydia Yahia-Cherif

“…Distinct brain atrophy patterns may already be seen in iRBD; however, how brain atrophy begins and progresses remains unclear. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…Abstract Tryptophan decarboxylase (TDC) is the rate-limiting enzyme in the biosynthesis of melatonin and plays a crucial role in melatonin production in plants. …”
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