Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
Get full text

Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
Get full text

Prospective Study of the Association Between Frailty and Health Care Utilization in Patients With Advanced CKD by Alice L. Kennard, Alice M. Richardson, Suzanne Rainsford, Kelly L. Hamilton, Nicholas J. Glasgow, Kate L. Pumpa, Angela M. Douglas, Girish S. Talaulikar

“…Negative binomial regression was used to model health care utilization patterns. Frailty progression over study follow-up was described using Cox proportional hazards modelling. …”
Get full text

Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen by Damien Gabriel, Julie Devos, Sandrine Chapuis, Alexandre Comte, Pierre-Edouard Billot

“…Heart rate increased with musical intensity in both conditions, while EEG data showed reduced arousal levels during the live performance, possibly reflecting deeper cognitive absorption. …”
Get full text

Stomata as the Main Pathway for the Penetration of Atmospheric Particulate Matter Pb into Wheat Leaves by Ke Zhang, Yujing Liang, Chuang Ma, Haopeng Guo, Fuyong Liu, Aihua Gao, Nan Liu, Hongzhong Zhang

“…In this study, spraying Pb(NO₃)₂ (Treatment T1) and spraying PbS (Treatment T2) were used as soluble and insoluble Pb, respectively, to evaluate the primary pathways of APM-Pb absorption by wheat leaves, as well as the translocation and accumulation patterns of Pb within the wheat plant. The results showed that both soluble and insoluble Pb can be absorbed by wheat leaves. …”
Get full text

Mechanism Analysis and Establishment of a Prediction Model for the Total Pressure Loss in the Multi-Branch Pipeline System of the Pneumatic Seeder by Wei Qin, Cheng Qian, Yuwu Li, Daoqing Yan, Zhuorong Fan, Minghua Zhang, Ying Zang, Zaiman Wang

“…This study aims to clarify the nonlinear pressure loss patterns of the pneumatic system in a pneumatic seeder under varying pipeline structures and airflow parameters, and to develop a rapid prediction equation for the main pipe’s pressure loss. …”
Get full text

Anemia in Patients with Axial Spondyloarthritis is Not Associated with an Increase of Arterial Stiffness and Intima-Media Thickness (Results of a Single-Center Cross-Sectional Stud... by K. N. Safarova, V. I. Makhina, K. D. Dorogoykina, A. P. Rebrov

“…We consider that potential protective effect of anemia, due to well-known pathophysiological patterns — a decrease in blood viscosity and the induction of nitric oxide synthesis, plays an important role. …”
Get full text

Prevalence, Risk Factors, and Antibiogram of Nontyphoidal Salmonella from Beef in Ambo and Holeta Towns, Oromia Region, Ethiopia by Endrias Zewdu Gebremedhin, Gezahegn Tafesse Soboka, Bizunesh Mideksa Borana, Lencho Megersa Marami, Edilu Jorga Sarba, Nega Desalegn Tadese, Hirut Abebe Ambecha

“…The Salmonella detection rate in abattoirs, butchers, and restaurants was 4.2% (5/118), 8.5% (10/118), and 4.2% (5/118), respectively. …”
Get full text

Evaluation of lung cancer early detection offered by the German Social Accident Insurance for formerly asbestos-exposed employees using low-dose computed tomography – setting and s... by Felix Greiner, Jan Heidrich, Helena Keller, Dirk Taeger, Thorsten Wiethege, Volker Harth

“…Primary endpoints are participation patterns, the rate of findings requiring further diagnostic investigation, the detection of lung cancer including tumour stage and characteristics, and the notification and recognition of asbestos-related occupational diseases. …”
Get full text

Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Descriptive statistics were used to summarize irAEs patterns and management approaches. Results: A total of 41 irAE episodes occurred among the 30 patients. …”
Get full text

Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Given these trends, male breast cancer remains a significant global health concern, and emerging disease patterns must inform new control policies.…”
Get full text

Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
Get full text

Sleep Restriction and Weekend Sleep Compensation Relate to Eating Behavior in School-Aged Children by Chamorro R, Garrido-González M, Gutierrez M, Santos JL, Weisstaub G

“…Actigraphic recordings measured sleep patterns for 4 consecutive days, including a weekend day. …”
Get full text

The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
Get full text

Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
Get full text

Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Current understanding of bacterial profiles, antibiotic resistance patterns, and the magnitude of Extended-Spectrum Beta-Lactamase (ESBL) and Carbapenemase (CP) producing isolates in critically ill patients is vital for implementing strong management approaches tailored to combat antibiotic resistance and improve patient outcomes. …”
Get full text

Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…Therefore, in this study, corrosion void formation and migration mechanism on a newly designed alloy (Ni–28Cr–13Al–5W-0.06B-0.005C) was investigated and the corrosion rate of the alloy was compared with that of Ni–20Cr alloy under simulated municipal solid waste (MSW) incineration conditions at 600 °C. …”
Get full text

Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection by Qingze Gu, Kevin Yuan, Jia Wei, Chang Ho Yoon, Anders Skyrud Danielsen, Augustine Luk, David W. Eyre, A. Sarah Walker

“…Here we investigated the association between serial CRP percentile changes, antibiotic prescribing patterns, and patient outcomes in a large cohort with suspected infection, acknowledging that CRP is one of multiple factors in clinical decision-making. …”
Get full text

Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches by Isabella D’Ambra, Isabella D’Ambra, Simona Saviano, Maria Assunta Ambrosio, Vincenzo Botte, Daniele Iudicone, Maria Grazia Mazzocchi, Louise Merquiol, Louise Merquiol, Louise Merquiol, Daniela Cianelli

“…Simulations indicated that surface circulation patterns promoted the permanence of medusae within the coastal area, particularly in summer. …”
Get full text

Catheter-associated Urinary Tract Infections in a trauma care facility in India: trend over ten years by Aparna Ningombam, Arpan Kumar Thakur, Ashish Kumar Srivastava, Sharin Varma, Madhavi Kirti, M. Nizam Ahmed, Vanlal Tluanpuii, Kapil Dev Soni, Richa Aggarwal, Gyanendra Pal Singh, Ashish Bindra, Navdeep Sokhal, Keshav Goyal, Kamran Farooque, Purva Mathur

“…This study focuses on the profile of CAUTI, the organism profile with antibiotic susceptibility patterns, and the clinical outcomes in the ICUs of a trauma care center. …”
Get full text