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4381
Exploring mobility data for enhancing HIV care engagement in Black/African American and Hispanic/Latinx individuals: a longitudinal observational study protocol
Published 2023-12-01“…Mobility data that measure individuals’ movements over time in combination with sociostructural data (eg, crime, census) can potentially identify barriers and facilitators to HIV care engagement and can enhance public health surveillance and inform interventions.Methods and analysis The proposed work is a longitudinal observational cohort study aiming to enrol 400 Black/African American and Hispanic/Latinx individuals living with HIV in areas of the USA with high prevalence rates of HIV. Each participant will be asked to share at least 14 consecutive days of mobility data per month through the study app for 1 year and complete surveys at five time points (baseline, 3, 6, 9 and 12 months). …”
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4382
Lignin Unlocks Stealth Carbon Sinks in Cold Seeps via Microbial Enzymatic Gatekeeping
Published 2025-01-01“…Our findings establish 3 paradigm shifts: (a) The turnover rates of terrestrial organic carbon are likely underestimated in deep-sea ecosystems; (b) microbial consortia employ combinatorial enzymatic strategies distinct from terrestrial decomposition regimes; (c) methyl shunting from lignin breakdown primes methanogenic precursors, revealing cryptic linkages between refractory carbon cycling and greenhouse gas reservoirs.…”
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4383
Cigarette Use, Lung Cancer Screening Eligibility and Completion Among Persons With Poor Mental Health
Published 2025-06-01“…Mechanisms to increase LCS rates among adults with mental health conditions are discussed.…”
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4384
Sex differences in the course of schizophrenia across diverse regions of the world
Published 2016-11-01“…Overall, females had slightly higher rates of clinical remission (58.0% vs 51.8%), functional remission (22.8% vs 16.0%), and recovery (16.5% vs 16.0%) at 36 months (P<0.001 for all). …”
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4385
Trends in visits to a 24-hour walk-in crisis mental health centre during the COVID-19 pandemic
Published 2025-07-01“…Mean weekly visits had the pandemic not occurred were predicted with an autoregressive integrated moving average model and compared with observed rates.ResultsTotal pre-pandemic CRC visits (14,280) decreased 22.1%–11,122 total post-pandemic CRC visits. …”
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4386
Clinical and radiographical analysis of percutaneous kyphoplasty with multi-point cement anchoring technique for preventing bone cement displacement in Kümmell’s disease of stage I...
Published 2025-06-01“…The operation time, volume of cement, VAS score, ODI score, cement distribution pattern and score, bone cement leakage, adjacent vertebra fracture, and bone cement displacement were compared between the two groups. …”
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4387
hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA
Published 2025-08-01“…However, it remains largely unclear whether A2B1 could function as a nucleic acid pattern-recognition receptor during cytoplasmic RNA virus infection. …”
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4388
Nutritional status, dietary inflammatory potential, and risk of osteosarcopenia: the Bushehr Elderly Health (BEH) program
Published 2025-06-01“…Abstract Background Osteosarcopenia is a growingly approved geriatric condition with a significant prevalence that contributes to higher rates of illness and death. Chronic inflammation and inadequate nutrition are key risk factors for numerous age-related diseases. …”
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4389
Seven New Irbesartan Salts: Significantly Improved Dissolution, Excellent Hygrothermal Stability, and Characteristic Supramolecular Synthons
Published 2025-04-01“…Their vitro dissolution, intrinsic dissolution rates (<i>IDR</i>s), thermal/hygroscopic stability (via thermal analysis, dynamic vapor sorption, and accelerated stability tests), and phase transition process (monitored by in situ Raman spectroscopy) were evaluated. …”
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4390
Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carci...
Published 2025-10-01“…Despite the transformative clinical impact of programmed cell death ligand 1/programmed death 1 (PD-1/PD-L1) blockade in hepatocellular carcinoma (HCC), therapeutic efficacy remains limited by the tumor immunosuppressive microenvironment (TIME), with objective response rates persistently below 20 %. To address this critical clinical challenge, we engineered ultrasound (US)-responsive lipid nanobubbles (NBs) co-encapsulating microRNA (miR)-195-5p and shikonin (SK) (designated miR-195-5p/SK-NBs), a dual-functional platform designed to synergize PD-L1 suppression with immunogenic cell death (ICD). …”
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4391
Machine Learning-Based Intrusion Detection Systems for the Internet of Drones: A Systematic Literature Review
Published 2025-01-01“…Existing Intrusion Detection Systems (IDS) for IoD face several limitations, including high false positive rates, resource constraints of drones, limited adaptability to evolving attack patterns, and a lack of standardized datasets for benchmarking, despite ongoing research efforts. …”
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4392
Global collaboration and innovation in malignant cerebral edema research: a bibliometric perspective
Published 2025-07-01“…AimMalignant cerebral edema (MCE) is a life-threatening complication of acute brain injuries, with mortality rates exceeding 80% in the absence of treatment. …”
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4393
Profiles and kinetics of PgRNA and clinical characteristics in pregnant, postpartum, and non-pregnant women with chronic HBV infection
Published 2025-07-01“…Moreover, the detection rates of pgRNA, DNA, and HBeAg varied significantly across the three stages and different treatment regimens in CHB women. pgRNA was highly correlated with HBeAg, and a moderate correlation was found between pgRNA and HBV DNA levels. …”
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4394
The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: A Qualitative Study
Published 2025-01-01“…Therefore, addressing organic versus conventional food in rural health care policies plays a vital role in improving the retention rates of CHWs. By recognizing the interconnectedness of nutrition and workforce sustainability, health care systems can better support Indigenous CHWs and continue delivering health care services.…”
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4395
The Risk of Vestibular Disorders with Semaglutide and Tirzepatide: Findings from a Large Real-World Cohort
Published 2025-04-01“…Tirzepatide users demonstrated similar patterns but lower absolute rates (0.10% at 6 months to 0.19% at 3 years vs. controls 0.04% to 0.15%), with hazard ratios from 3.19 (95% CI: 2.11–4.81) to 4.55 (95% CI: 3.43–6.03). …”
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4396
Analyzing the Contents of a Large, Public Online Peer Support Forum for Obsessive-Compulsive Disorder: Thematic Analysis
Published 2025-05-01“… Abstract BackgroundObsessive-compulsive disorder (OCD) is a debilitating chronic anxiety disorder with low rates of remission. r/OCD is a peer support forum hosted by the Reddit website with over 180,000 users and 100‐200 new posts daily. …”
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4397
Immunohistochemical analysis of IDH1, ATRX, p53, and Ki-67 in glioblastoma and diffuse infiltrative glioma: Therapeutic and prognostic correlation
Published 2025-01-01“…Kaplan-Meier method and Cox proportional regression model (forward model) were used to estimate the mean and median survival times, failure rates, and hazard ratios. Results. In the study, 115 (56.1%) patients were male and 90 (43.9%) were female. …”
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4398
Dietary strategies for preventing and managing obesity through evidence-based nutritional interventions
Published 2025-07-01“…This crisis is driven by multifaceted factors, including sedentary lifestyles, urbanization, dietary transitions, and behavioral influences. As obesity rates continue to rise, dietary interventions emerge as crucial and modifiable strategies for prevention and management. …”
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4399
Clinical value and survival analysis of subcutaneous soft tissue metastasis detected by 18F-FDG PET/CT
Published 2025-04-01“…Collect patient histological subtypes, metastasis patterns, treatment, and survival rates. Kaplan Meier curves were used to estimate survival time, and Mantel-Cox univariate analysis was used to determine the correlation between extensive metastasis, degree of soft tissue involvement, systemic and local treatment, and survival time.ResultAmong the 57 patients confirmed by pathology, 10 were benign and 47 were malignant. …”
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4400
Association between neutrophil-to-lymphocyte ratio and all-cause and cardiovascular mortality among adults with cancer from NHANES 2005-2018: a retrospective cohort study
Published 2025-03-01“…Subgroup analysis showed similar patterns (all p-values for interaction > 0.05). …”
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