The Global Burden of Multidrug-Resistant Bacteria by Andrea Marino, Antonino Maniaci, Mario Lentini, Salvatore Ronsivalle, Giuseppe Nunnari, Salvatore Cocuzza, Federica Maria Parisi, Bruno Cacopardo, Salvatore Lavalle, Luigi La Via

“…We evaluate the effectiveness of various antimicrobial stewardship programs, documenting success rates and implementation challenges across different healthcare settings. …”
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Responses of Biomass and Allometric Growth Equations of Juvenile Mangrove Plants to Salinity, Flooding, and Aboveground Competition by Kaijie Hu, Wei Wang, Wei Qian, Nong Sheng, Jiliang Cheng, Yanmei Xiong

“…To enhance juvenile mangrove survival rates and develop precise carbon sequestration models, this study examines biomass accumulation patterns and allometric equation development under diverse environmental and biological conditions. …”
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Machine learning-based source apportionment and source-oriented probabilistic ecological risk assessment of heavy metals in urban green spaces by Jun Li, Jia-Yi Lu, Xin-Ying Tuo, Chao Wang, Jun-Zhuo Liu, Zhan-Dong Gao, Cun-Hao Yu, Fei Zang

“…Results showed that the average concentrations of Cd (0.38 mg kg−1), Cu (35.51 mg kg−1), Hg (0.07 mg kg−1), Pb (34.59 mg kg−1), and Zn (130.58 mg kg−1) exceeded local soil background values, except for As (8.56 mg kg−1), Cr (62.77 mg kg−1), and Ni (27.68 mg kg−1). Notably, exceedance rates for Cd, Hg, Pb, and Zn were 90.91 %, 94.95 %, 80.81 %, and 87.88 %, respectively. …”
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The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment by Yipin Lu, Peng Xu, Sha Li, Jie Yao

“…A pan-cancer analysis was performed to evaluate JPT1 expression patterns and prognostic value across multiple cancer types. …”
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Prediction efficiency and incremental processing strategy during spoken language comprehension in autistic children: an eye-tracking study by Zihui Hua, Tianbi Li, Ruoxi Shi, Ran Wei, Li Yi

“…However, autistic children exhibited reduced prediction efficiency compared to neurotypical peers, evidenced by significantly lower proportions of and slower growth rates in fixations to target objects relative to unrelated distractors, and delayed onset of predictive looking. …”
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Inflammatory markers mediate the association between alternative adiposity indices and mortality in patients with rheumatoid arthritis: data from NHANES 1999–2018 by Feng Luo, Jia-jie Guo, Xue-mei Yuan, Heng Zhou, Qiu-yi Wang, Chang-ming Chen, Xue-ming Yao, Wu-kai Ma

“…Conclusions This study revealed a potential clinical value of a new obesity index, specifically the ABSI, in predicting the survival rates among individuals with RA. Inflammatory markers appear to play a partial mediating role in this relationship. …”
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Spatial distribution and predictors of early childbearing among Ethiopian women: evidence from the 2016 Ethiopian Demographic and Health Survey by Amare Teshome Tefera, Fanuel Gashaw, Martha Solomon, Nebiyu Bekele, Shegaye Shumet, Tigist Mulugeta, Araya Mesfin Nigatu, Solomon Gedlu Nigatu

“…Abstract Background Age at first birth is a crucial factor in understanding fertility patterns within a population. Ethiopia reports high rates of maternal and child mortality alongside elevated fertility levels. …”
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Topologically Optimized Anthropomorphic Prosthetic Limb: Finite Element Analysis and Mechanical Evaluation Using Plantogram-Derived Foot Pressure Data by Ioannis Filippos Kyriakidis, Nikolaos Kladovasilakis, Marios Gavriilopoulos, Dimitrios Tzetzis, Eleftheria Maria Pechlivani, Konstantinos Tsongas

“…This innovative approach allows the development of tailored prosthetic limbs with optimal replication of the human motion patterns, resulting in improved patient outcomes and higher success rates. …”
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Comparison of neoadjuvant chemoimmunotherapy with planned surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung c... by Yana Qi, Xiaoyang Zhai, Qinhao Xu, Yuqin Jin, Yingfan Guo, Miaoqing Zhao, Hui Zhu, Hongbo Guo

“…Median overall survival (OS) was NR in either group, with 3-year OS rates of 87.5% in the neoCT/IO group and 75.0% in the cCRT + IO group (p = 0.22). …”
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Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014-2024) ClinSurv HIV cohort: A large case series. by Ali Mert, Okan Derin, Esra Zerdali, Abdurrahman Kaya, Özlem Gül, Deniz Borcak, Ahmet Furkan Kurt, Meliha Meriç Koç, Bircan Kayaaslan, Ayşe Batırel, Alper Gündüz, İnci Yılmaz Nakir, Gülşen Yörük, Dilek Yıldız Sevgi, Hayat Kumbasar Karaosmanoğlu, Bilgül Mete, Melike Nur Özçelik, Nagehan D Sarı, Yasemin Akkoyunlu, Fehmi Tabak

“…The positivity rates of Ehrlich-Ziehl-Neelsen staining (EZN), polymerase chain reaction (PCR), and TB cultures in clinical samples were found to be 47.5%, 72.5%, and 53%, respectively. …”
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Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
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Effects of timing of abomasal infusion of fatty acids on the daily rhythms of milk synthesis and plasma hormones and metabolites in dairy cows by I.J. Salfer, P.A. Bartell, K.J. Harvatine

“…Both de novo and mixed-source fatty acid yields were reduced by DAY and NGT, suggesting that the faster infusion rates may have resulted in concentrations of fatty acids that exceeded a threshold sufficient to inhibit de novo fatty acid synthesis. …”
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Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
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Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
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Survival outcomes and prognostic impact of adjuvant chemotherapy in stage IB lung adenocarcinoma with cribriform component by Rongyang Li, Yu Zhang, Jianhao Qiu, Mingyang Zang, Zhenguo Sun

“…The results showed that both the 5-year overall survival (OS) rates (63.5% vs. 84.5%, P = 0.013) and 5-year recurrence-free survival (RFS) rates (58.7% vs. 77.7%, P = 0.033) for cribriform-positive patients were lower than those for cribriform-negative patients. …”
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Designing for Engagement in Primary Health Education Through Digital Game-Based Learning: Cross-National Behavioral Evidence from the iLearn4Health Platform by Evgenia Gkintoni, Emmanuella Magriplis, Fedra Vantaraki, Charitini-Maria Skoulidi, Panagiotis Anastassopoulos, Alexandra Cornea, Begoña Inchaurraga, Jaione Santurtun, Ainhoa de la Cruz Mancha, George Giorgakis, Kleri Kouppas, Stella Timotheou, Maria Jose Moreno Juan, Miren Muñagorri, Marta Harasiuk, Alfredo Garmendia Lopez, Efi Skoulidi, Apostolos Vantarakis

“…The study employed multiple statistical approaches—descriptive analysis, correlation analysis, ANOVA, regression modeling, and cluster analysis—to identify design engagement patterns and their predictors, tracking completion rates, progress trajectories, and interaction time as indicators of design effectiveness. …”
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Ornidazole-Induced Liver Injury: The Clinical Characterization of a Rare Adverse Reaction and Its Implications from a Multicenter Study by Ali Rıza Çalışkan, Ilker Turan, Sezgin Vatansever, Jasmin Weninger, Emine Türkmen Şamdancı, Ayşe Nur Akatli, Elvan Işık, Esra Durmazer, Ayşenur Arslan, Nilay Danış, Hüseyin Kaçmaz, Sedat Cicek, Osman Sağlam, Dilara Turan Gökçe, Derya Arı, Sevinç Tuğçe Güvenir, Serkan Yaraş, Cumali Efe, Meral Akdoğan Kayhan, Murat Harputluoğlu, Ali Canbay, Ulus Salih Akarca, Zeki Karasu, Ramazan Idilman, Fulya Günşar

“…Corticosteroids were used in 24.8% of cases (n = 25) and were associated with higher ANA positivity and a 20% (n = 5) relapse rate post-discontinuation. Recovery was achieved in 87.7% of cases (n = 88), while 7.9% of cases (n = 8) required liver transplantation and 4% (n = 4) died. …”
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Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Elvira Favoino, Federico Perosa, Annamaria Iagnocco, Roberto Giacomelli, Francesco Ciccia

“…SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50–69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. …”
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COMPLEX ELECTROMAGNETIC MONITORING OF GEODYNAMIC PROCESSES IN THE NORTHERN TIEN SHAN (BISHKEK GEODYNAMIC TEST AREA) by E. A. Bataleva, V. A. Mukhamadeeva

“…The data from the 2004–2016 KNET Catalogue of the Research Station of RAS were analyzed in order to investi‐ gate the relationship between the space‐time seismicity distribution and the electrical conductivity variations that correspond to the features of the seismicity pattern at depth. …”
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Comparative Analysis of Mineralogical Composition and Radioactivity Levels in Stone Samples from the Archaeological Site of <i>Halaesa</i> (Sicily, Italy) by Giuseppe Paladini, Paola Cardiano, Francesco Caridi, Lorenzo Pistorino, Domenico Majolino, Francesco Gregorio, Stefania Lanza, Gabriele Lando, Antonio Francesco Mottese, Marco Miano, Olivia Gómez-Laserna, Valentina Venuti

“…Moreover, the specific activity of radionuclides (²²⁶Ra, ²³²Th, and ⁴⁰K) and the ²²²Rn exhalation rates were measured, enabling the estimation of a set of radiological indices that assess potential health hazards associated with prolonged exposure to these lithic materials. …”
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