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2961
Is pyroptosis a brake or an accelerator in the fate of the tumor?
Published 2025-07-01“…Patients afflicted with malignancies typically endure diminished survival rates and compromised quality of life. Consequently, the paramount objective of oncological research lies in redefining cancer from a terminal diagnosis to a clinically manageable condition, thereby realizing this transformative medical paradigm. …”
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2962
Global burden and trends of self-harm from 1990 to 2021, with predictions to 2050
Published 2025-05-01“…Globally, the burden of self-harm was higher for males than for females. DALYs rates were highest among adolescents and young adults (20-29 years), whereas mortality rates showed a predominantly age-progressive pattern with the highest burden observed in middle-aged and older populations, albeit with a modest decline in the oldest age groups. …”
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2963
Gene expression in uterine leiomyoma from tumors likely to be growing (from black women over 35) and tumors likely to be non-growing (from white women over 35).
Published 2013-01-01“…Growth rates for leiomyoma were on average much higher from older black women than for older white women, and we now report gene expression pattern differences in tumors from these two groups of study participants. …”
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2964
Economic Clues to Crime: Insights from Mongolia
Published 2025-06-01“…The empirical findings reveal that detection rates exert a statistically significant deterrent effect on robbery in the short term, while incarceration rates are effective in reducing theft. …”
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2965
Understanding the demographic and socioeconomic determinants of morbidity in Eastern Uganda: a retrospective analysis of the Iganga-Mayuge health and demographic surveillance data
Published 2024-12-01“…Noteworthy demographic variations, particularly gender and age, significantly impact disease distribution, revealing higher diagnosis rates among females. Additionally, socioeconomic factors, including education and wealth status, contribute to discernible differences in disease burden.Conclusion This research provides crucial insights into the implications of demographic and socioeconomic factors on disease burden in Uganda. …”
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2966
Comparative Sensitivity Analyses of Energy Consumption in Response to Average Speed Between Electric Vehicles and Conventional Vehicles: Case Study in Beijing, China
Published 2025-04-01“…This discrepancy is primarily attributed to differences in energy consumption rates rather than variations in driving behavior, as reflected in VSP distributions.…”
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2967
Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients
Published 2019-01-01“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
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2968
Smart Grid Intrusion Detection for IEC 60870-5-104 With Feature Optimization, Privacy Protection, and Honeypot-Firewall Integration
Published 2025-01-01“…The experimental results demonstrate the framework’s operational capability and effectiveness for SCADA network security, achieving 99.29% accuracy, 94.8% recall and 4.1% false positive rates.…”
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2969
Whole-Genome Sequence-Based Diversity of <i>Mycobacterium tuberculosis</i> Strains Isolated from a Central Western Region of Mexico
Published 2025-05-01“…Tuberculosis remains a significant health issue in Mexico, which has one of the highest incidence rates in the Americas. This study aimed to analyze the circulating sublineages, spoligotypes, drug resistance, and transmission patterns of <i>Mycobacterium tuberculosis</i> in Mexico’s Central Western region using whole-genome sequencing. …”
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2970
The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution
Published 2024-09-01“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
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2971
Near-Unity Nitrate to Ammonia conversion via reactant enrichment at the solid-liquid interface
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2972
Prevalence and Antibiotic Resistance of Bacteria Isolated from Cerebrospinal Fluid of Neurosurgical Patients in Malang, Indonesia
Published 2023-12-01“…Conclusions: The sensitivity rates of ceftriaxone and meropenem were found to be 0% and 100%, respectively. …”
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2973
Sex determination and stature estimation using logistic and linear regression models: A population-specific study of tibia and Fibula in Northeastern Thais
Published 2025-09-01“…Results: For sex determination, the results showed that univariate logistic regression models achieved the accuracy rates up to 87.50 %, with maximum proximal epiphyseal breadth of the tibia demonstrating highest discriminatory power. …”
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2974
Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved]
Published 2025-04-01“…Conclusions This study's findings underscore the heightened vulnerability of hospitalized COVID-19 patients with cancer, revealing a higher mortality rate, longer hospital stays, and an unstructured pattern of care that reflects the complexity of managing severely ill patients during a public health crisis like the COVID-19 pandemic.…”
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2975
Wild Ungulate Prey Size and Feeding Group Demographic Structure Affect Interactions and Per Capita Food Intake of African Pride Lions in East African Maasai Steppe
Published 2025-08-01“…However, subadults increased their per capita intake rates when feeding together with both cubs and adult females. …”
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2976
Toll-like receptor 4 promotes proliferation and apoptosis resistance in human papillomavirus–related cervical cancer cells through the Toll-like receptor 4/nuclear factor-κB pathwa...
Published 2017-06-01“…Proliferation of HeLa and Caski cells was promoted in lipopolysaccharide-stimulated groups but suppressed in short hairpin RNA–transfected groups. Apoptosis rates were lower in lipopolysaccharide-stimulated groups relative to short hairpin RNA–transfected groups. …”
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2977
Global, regional, and national burden of sudden infant death syndrome and the impact of COVID-19: a trend and health inequality analysis based on the global burden of disease study...
Published 2025-07-01“…Age-standardized DALY rates (ASDR; per 100,000 population) with 95% uncertainty intervals (UIs) were calculated for 204 countries and territories, stratified by age, location, and socio-demographic index (SDI).ResultsIn 2021, the ASDR of SIDS accounted for 44.16 (95% UI: 25.70–59.26) per 100,000 population globally, which was a 58.97% decrease from 1990. …”
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2978
Spectrum and epidemiology of rare diseases in a Chinese natural population of 14.31 million residents, 2012–2023
Published 2025-08-01“…Age-standardized incidence rates (ASIR) were calculated per 100,000 person-years with 95% confidence intervals. …”
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2979
Six decades of global crop yield increase and cropland expansion from 1960 to 2020
Published 2025-01-01“…Brazil, Indonesia, Thailand, Colombia, and Malaysia), had both the highest crop yield increases and cropland expansion rates. By analysing the relationship of annual crop yield and cropland area changes, we see potential rebound effects of yield increases in tropical lowlands of low- to middle-income countries. …”
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2980
Influence of model selection on optimal control of traffic for emissions minimisation
Published 2025-01-01“…However, at a microscopic level (e.g. acceleration, deceleration rates, and deviations from the mean), pronounced differences became evident. …”
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