Inflammatory markers mediate the association between alternative adiposity indices and mortality in patients with rheumatoid arthritis: data from NHANES 1999–2018 by Feng Luo, Jia-jie Guo, Xue-mei Yuan, Heng Zhou, Qiu-yi Wang, Chang-ming Chen, Xue-ming Yao, Wu-kai Ma

“…Conclusions This study revealed a potential clinical value of a new obesity index, specifically the ABSI, in predicting the survival rates among individuals with RA. Inflammatory markers appear to play a partial mediating role in this relationship. …”
Get full text

Spatial distribution and predictors of early childbearing among Ethiopian women: evidence from the 2016 Ethiopian Demographic and Health Survey by Amare Teshome Tefera, Fanuel Gashaw, Martha Solomon, Nebiyu Bekele, Shegaye Shumet, Tigist Mulugeta, Araya Mesfin Nigatu, Solomon Gedlu Nigatu

“…Abstract Background Age at first birth is a crucial factor in understanding fertility patterns within a population. Ethiopia reports high rates of maternal and child mortality alongside elevated fertility levels. …”
Get full text

Comparison of neoadjuvant chemoimmunotherapy with planned surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung c... by Yana Qi, Xiaoyang Zhai, Qinhao Xu, Yuqin Jin, Yingfan Guo, Miaoqing Zhao, Hui Zhu, Hongbo Guo

“…Median overall survival (OS) was NR in either group, with 3-year OS rates of 87.5% in the neoCT/IO group and 75.0% in the cCRT + IO group (p = 0.22). …”
Get full text

Epidemiological and clinical analysis, and outcomes of tuberculosis co-infection among people living with HIV in Türkiye (2014-2024) ClinSurv HIV cohort: A large case series. by Ali Mert, Okan Derin, Esra Zerdali, Abdurrahman Kaya, Özlem Gül, Deniz Borcak, Ahmet Furkan Kurt, Meliha Meriç Koç, Bircan Kayaaslan, Ayşe Batırel, Alper Gündüz, İnci Yılmaz Nakir, Gülşen Yörük, Dilek Yıldız Sevgi, Hayat Kumbasar Karaosmanoğlu, Bilgül Mete, Melike Nur Özçelik, Nagehan D Sarı, Yasemin Akkoyunlu, Fehmi Tabak

“…The positivity rates of Ehrlich-Ziehl-Neelsen staining (EZN), polymerase chain reaction (PCR), and TB cultures in clinical samples were found to be 47.5%, 72.5%, and 53%, respectively. …”
Get full text

Conversational AI agent for precision oncology: AI-HOPE-WNT integrates clinical and genomic data to investigate WNT pathway dysregulation in colorectal cancer by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal, Enrique Velazquez-Villarreal

“…Exploratory queries further assessed treatment response, co-mutation patterns, and population-specific trends.ResultsIn recapitulation analyses, AI-HOPE-WNT reproduced key trends from prior work, including improved survival in WNT-altered EOCRC and higher RNF43 mutation rates in Hispanic/Latino (H/L) populations compared to non-Hispanic White (NHW) people. …”
Get full text

Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
Get full text

Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
Get full text

Survival outcomes and prognostic impact of adjuvant chemotherapy in stage IB lung adenocarcinoma with cribriform component by Rongyang Li, Yu Zhang, Jianhao Qiu, Mingyang Zang, Zhenguo Sun

“…The results showed that both the 5-year overall survival (OS) rates (63.5% vs. 84.5%, P = 0.013) and 5-year recurrence-free survival (RFS) rates (58.7% vs. 77.7%, P = 0.033) for cribriform-positive patients were lower than those for cribriform-negative patients. …”
Get full text

Ornidazole-Induced Liver Injury: The Clinical Characterization of a Rare Adverse Reaction and Its Implications from a Multicenter Study by Ali Rıza Çalışkan, Ilker Turan, Sezgin Vatansever, Jasmin Weninger, Emine Türkmen Şamdancı, Ayşe Nur Akatli, Elvan Işık, Esra Durmazer, Ayşenur Arslan, Nilay Danış, Hüseyin Kaçmaz, Sedat Cicek, Osman Sağlam, Dilara Turan Gökçe, Derya Arı, Sevinç Tuğçe Güvenir, Serkan Yaraş, Cumali Efe, Meral Akdoğan Kayhan, Murat Harputluoğlu, Ali Canbay, Ulus Salih Akarca, Zeki Karasu, Ramazan Idilman, Fulya Günşar

“…Corticosteroids were used in 24.8% of cases (n = 25) and were associated with higher ANA positivity and a 20% (n = 5) relapse rate post-discontinuation. Recovery was achieved in 87.7% of cases (n = 88), while 7.9% of cases (n = 8) required liver transplantation and 4% (n = 4) died. …”
Get full text

Type II diabetes in systemic sclerosis patients: insights from an observational, multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) by Vasiliki Liakouli, Giulio Forte, Piero Ruscitti, Luca Navarini, Francesca Bellisai, Francesco Caso, Giuliana Guggino, Lidia La Barbera, Chiara Rizzo, Ada Corrado, Paola Triggianese, Alberto Lo Gullo, Giuseppe Mandraffino, Luca Cantarini, Bruno Frediani, Paola Cipriani, Francesco Paolo Cantatore, Maria Sole Chimenti, Elvira Favoino, Federico Perosa, Annamaria Iagnocco, Roberto Giacomelli, Francesco Ciccia

“…SSc patients with T2D were significantly older (P < 0.007) and exhibited: higher prevalence of late-stage capillaroscopic pattern (P < 0.001), severe reduction in forced vital capacity (FVC < 50%; P < 0.000), moderate reduction in total lung capacity (TLC 50–69%; P < 0.011), electrocardiographic signs of right ventricular hypertrophy (P < 0.018), higher prevalence of pulmonary arterial hypertension (PAH) confirmed by right heart catheterization (RHC) (P < 0.037) and higher prevalence scleroderma renal crisis (SRC) (P < 0.001); elevated erythrocyte sedimentation rate (ESR) (P < 0.022), and ANA positivity. …”
Get full text

COMPLEX ELECTROMAGNETIC MONITORING OF GEODYNAMIC PROCESSES IN THE NORTHERN TIEN SHAN (BISHKEK GEODYNAMIC TEST AREA) by E. A. Bataleva, V. A. Mukhamadeeva

“…The data from the 2004–2016 KNET Catalogue of the Research Station of RAS were analyzed in order to investi‐ gate the relationship between the space‐time seismicity distribution and the electrical conductivity variations that correspond to the features of the seismicity pattern at depth. …”
Get full text

OUTLIER IDENTIFICATION ON PENALIZED SPLINE REGRESSION MODELING FOR POVERTY GAP INDEX IN JAVA by Anggita Rizky Fadilah, Anwar Fitrianto, I Made Sumertajaya

“…Three of six provinces, including DI Yogyakarta, Central Java, and East Java still have poverty rates above national rates in March 2020. This problem indicates that an imbalance in poverty happens between those regions. …”
Get full text

Thalamic nuclei volumes are related to disease stage in patients with amyotrophic lateral sclerosis by Tianrui Wen, Tianrui Wen, Jun Zhu, Jun Zhu, Sujuan Sun, Sujuan Sun, Yujing Chen, Yujing Chen, Ninglu Gao, Ninglu Gao, Mingjie Ma, Xinyue Chen, Shuangwu Liu, Shuangwu Liu, Pengfei Lin, Yan Deng

“…We investigated patterns of thalamic atrophy in the patients and in 94 healthy controls (HCs). …”
Get full text

Feasibility Assessment of an Optically Powered Digital Retinal Prosthesis Architecture for Retinal Ganglion Cell Stimulation by William Lemaire, Maher Benhouria, Konin Koua, Wei Tong, Gabriel Martin-Hardy, Melanie Stamp, Kumaravelu Ganesan, Louis-Philippe Gauthier, Marwan Besrour, Arman Ahnood, David John Garrett, Sebastien Roy, Michael R. Ibbotson, Steven Prawer, Rejean Fontaine

“…This confirms the feasibility of generating a response in RGCs with an infrared-powered digital architecture capable of delivering complex sequential stimulation patterns at high repetition rates, albeit with some limitations.…”
Get full text

Transdiagnostic body dissatisfaction: comparing adolescents with anorexia nervosa and depression during body exposure by Valeska Stonawski, Lena Sasse, Laura Derks, Gunther H. Moll, Oliver Kratz, Tanja Legenbauer, Stefanie Horndasch

“…BD was assessed with questionnaires; valence ratings were obtained for different body parts. Emotion ratings and gaze patterns towards the own body were assessed during each session via rating scales and eye-tracking. …”
Get full text

Optimizing jacket design for two-wheeler delivery workers during rainy conditions by Sujin Lim, Jisoo Ha

“…Also riders to make as many deliveries as possible and receive good ratings, most work more than 8 h. This complex work environment and long working hours expose them to physical fatigue, scrapes, bumps, falls, and other accidents, making it more necessary than ever to pay attention to the health and safety of delivery riders. …”
Get full text

Sewage sludge from Taxco de Alarcón wastewater treatment plant as substrate to cultivate Panicum maximum by Erik Yoel Carreto-Morales, Jazmin Alaide López-Díaz, Mariana Martínez-Castrejón, Oscar Talavera-Mendoza, Roberto Carlos Almazán-Núñez, Giovanni Hernández-Flores

“…The response variables analyzed for MG were germination time (one month after plant emergence), height (HMG), growth rate GrMG, and yield (YMG), whereas in the SS and PS the content of organic matter was analyzed. …”
Get full text

Hydroformer: Frequency Domain Enhanced Multi‐Attention Transformer for Monthly Lake Level Reconstruction With Low Data Input Requirements by Minglei Hou, Jiahua Wei, Yang Shi, Shengling Hou, Wenqian Zhang, Jiaqi Xu, Yue Wu, He Wang

“…The model exhibited good performance even when training data missing rates were below 50%, particularly in lakes with significant seasonal fluctuations. …”
Get full text

Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…Abstract Tryptophan decarboxylase (TDC) is the rate-limiting enzyme in the biosynthesis of melatonin and plays a crucial role in melatonin production in plants. …”
Get full text

Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries by Xiao Zhang, Anne Abio, David M Ndetei, Samir Kumar Praharaj, Wan Mohd Azam Wan Mohd Yunus, Yuko Mori, Zahra Kafami Khorasani, Sonja Gilbert, Meytal Grimland, Nikita Bezborodovs, Sanju Silwal, Minja Westerlund, Hitoshi Kaneko, Emmi Heinonen, Andre Sourander

“…It highlights the need to address methodological heterogeneity, including the use of validated and culturally adapted measures, comprehensive reporting of sampling procedures, sample sizes, response rates and greater attention to generalisability. …”
Get full text