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2601
Impact of the agri-geographical transformation of rural settlements on the geospatial dynamics of soil erosion intensity in municipalities of Central Serbia
Published 2025-08-01“…Cluster analysis (CA) was used to differentiate rural areas of municipalities based on selected indicators. The highest rates of soil erosion intensity reduction were found in the regressive and dominantly regressive types (average specific gross erosion 1971: Ws1 = 980 m3/km2/year; 2011: Ws2 = 587 m3/km2/year). …”
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2602
In silico and in vitro assessment of TP53, ATM, RAD51, and BAX genes in gastric cancer and their contribution to radiotherapy resistance
Published 2025-07-01“…Mutational analysis showed that TP53 was altered in 88% of gastric cancer samples, while ATM, RAD51, and BAX exhibited lower mutation rates. Survival analysis suggested that elevated expression of TP53, RAD51, and BAX may be linked to poorer survival outcomes, while reduced ATM expression appeared to associate with decreased overall survival. …”
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2603
Decoding stimulus-specific regulation of promoter activity of p53 target genes
Published 2025-06-01“…Indeed, stimulus-specific stochastic gene expression is predominantly regulated by promoter activation and deactivation rates. Interestingly, we found that in many situations, transcriptional activity was uncoupled from the total amount of p53 and the fraction bound to DNA, highlighting that transcriptional regulation by p53 is a multi-dimensional process. …”
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2604
Is mechanism of injury associated with outcome in spinal trauma? An observational cohort study from Tanzania.
Published 2024-01-01“…Improved neurological outcomes were associated with incomplete injuries (AIS B-D), while higher mortality rates were linked to cervical injuries and complete (AIS A) injuries.…”
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2605
Direct and Indirect Protection with Pediatric Quadrivalent Live-Attenuated Influenza Vaccination in Europe Estimated by a Dynamic Transmission Model
Published 2017-07-01“… # Conclusions The model highlights direct and indirect protection benefits when vaccinating healthy children with QLAIV in Europe, across a range of demographic structures, contact patterns and vaccination coverage rates.…”
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2606
Century-Long Cycles of Evolution of the Country’s Active Population
Published 2025-07-01“…The collected factual material allows us to draw a conclusion about the general patterns of creative activity of the population both at the beginning of the last century and in our years. …”
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2607
A Retrospective Analysis of CLL Patients in a Romanian Hematology Center
Published 2025-06-01“…Time to first treatment (TTFT), treatment patterns, and response rates were evaluated. Statistical tests included MannWhitney U and Fisher’s exact test, with p < 0.05 considered significant. …”
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2608
Impact of COVID-19 on mucormycosis presentation and laboratory values: A comparative analysis.
Published 2025-01-01“…The study compared patient laboratory studies and presentation symptoms between COVID-19 history-positive and COVID-19 history-negative groups, with a particular focus on mortality rates and associated comorbidities such as diabetes, cancer and immunosuppressive treatment.…”
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2609
Immunosenescence-Related Gene MAFF is Involved in Immune Regulation and Malignant Progression in Pancreatic Adenocarcinoma
Published 2025-07-01“…The elevated-risk cohort, as identified by the risk assessment metric, correlates with poorer survival rates. Additionally, we uncover an association between the risk indicator and the tumor milieu, encompassing immune cell infiltration patterns and drug sensitivity profiles. …”
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2610
Burden and inequality of autism spectrum disorders in global, East asian, and Southeast Asian regions, 1990–2021: result from the global burden of disease study 2021
Published 2025-08-01“…Abstract Introduction Autism Spectrum Disorders (ASD) represent a range of neurodevelopmental conditions characterized by abnormal behavioral patterns. ASD is frequently comorbid with other neurodevelopmental disorders. …”
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2611
Intramedullary nailing with and without cerclage in subtrochanteric fractures: an updated systematic review and meta-analysis
Published 2025-08-01“…No significant differences were observed in non-union, infection, or mortality rates. Quality assessment using the Newcastle–Ottawa Scale indicated high quality studies. …”
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2612
INFLUENCE OF THE EVAPORITE FORMATION STRUCTURE ON SALT TECTONICS AND HYDROCARBON TRAPS (BY THE RESULTS OF NUMERICAL SIMULATION OF HALOKINESIS IN THE PRE-CASPIAN)
Published 2023-04-01“…Since halokinesis is the main factor controlling the migration and accumulation of hydrocarbons in the Preaspian region, background and aim of prospecting and exploration require identifying the specifics of the formation of various types of salt structures and the relationship between their location patterns and halokinesis process.Numerical simulation shows that, depending on the instable layer thickness and its relationship with the total thickness of the overlying layers, the instability development occurs at different rates, forming different types of structures. …”
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2613
The tsunami of antibiotic resistance as a global health crisis in otorhinolaryngology patients; a cross-sectional study
Published 2025-08-01“…Objective Due to the desperate need for sustainable access to effective antibiotic the patterns of antimicrobial resistance among ORL patients in Egypt were studied and the implications for clinical management and public health were assessed. …”
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2614
Do older parents do better? Relationships between parental age, chick body condition and migratory behaviour in a colonial‐breeding waterbird
Published 2025-05-01“…In differential migration systems, low‐quality or socially subordinate individuals may be constrained to sub‐optimal migratory behaviours associated with lower demographic rates. Therefore, producing high‐quality chicks may enhance the survival of offspring. …”
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2615
RiverBedDynamics v1.0: a Landlab component for computing two-dimensional sediment transport and river bed evolution
Published 2025-06-01“…By dynamically coupling RiverBedDynamics with Landlab's hydrodynamic flow solver, OverlandFlow, we created a new LEM capable of simulating the dynamics of local shear stresses, bed load transport rates, and grain size distributions. Comparisons of our LEM results with analytical and previously reported solutions demonstrate its ability to accurately predict time-varying local changes in bed surface elevation, including erosion and deposition, as well as grain size distribution. …”
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2616
Prevalence and determinants of apparent treatment-resistant hypertension among patients in South African primary care: a single-centre observational study
Published 2025-05-01“…South Africa, like other low-middle-income countries, faces a disproportionate burden due to the increasing prevalence of hypertension, exacerbated by low awareness, treatment, and control rates. Treatment-resistant hypertension (TRH) is a complex clinical entity and poses significant obstacles to achieving therapeutic goals. …”
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2617
Building a dynamic web calculator for individualized conditional survival estimation in brainstem ependymoma
Published 2025-07-01“…CS analysis was performed to assess changes in survival probability over time. Annual hazard rates were calculated to identify high-risk periods. …”
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2618
SmartTrust: a hybrid deep learning framework for real-time threat detection in cloud environments using Zero-Trust Architecture
Published 2025-07-01“…The model achieved detection rates of 99.19% for insider threats, 98.23% for privilege escalation, and 99.27% for data breaches while reducing false positives by over 40% compared to existing approaches. …”
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2619
Impact of Climate Variability on Coffee Production in Kambuga Sub-County Kanungu District.
Published 2024“…The findings showed that climatic factors that have affected coffee production in Kambuga sub-county, Kanungu district include; Temperature, Rainfall Patterns, Pests and Diseases, Rainfall, Humidity, and Climate Extremes. …”
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2620
Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and...
Published 2025-07-01“…The overall LN metastatic rate was 31%; metastasis was found mostly in the mandibular lymph center (83%). …”
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