Transcriptome Profiling Reveals Genetic Basis of Muscle Development and Meat Quality Traits in Chinese Congjiang Xiang and Landrace Pigs by Jiada Yang, Qiaowen Tang, Chunying Sun, Qiuyue Li, Xiaoyu Li, Lu Hou, Yi Yang, Kang Yang

“…RNA sequencing was performed on muscle tissues from ten individuals of each breed, generating 874.5 million raw reads with an average mapping rate of 89.3% to the pig reference genome. (3) Results: Transcriptional profiling revealed distinct expression patterns with 785 genes exclusively expressed in CX pigs and 457 genes unique to LAN pigs, while 7099 co-expressed genes were shared by both breeds. …”
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Lymphatic system is the mainstream for breast cancer dissemination and metastasis revealed by single-cell lineage tracing by Kai Miao, Aiping Zhang, Xiaodan Yang, Yipeng Zhang, Anqi Lin, Lijian Wang, Xin Zhang, Heng Sun, Jun Xu, Jingyao Zhang, Yuzhao Feng, Fangyuan Shao, Sen Guo, Zhihui Weng, Peng Luo, Dong Wang, Shuai Gao, Xiao-Yang Zhao, Xiaoling Xu, Chu-Xia Deng

“…In this study, we applied a barcoding system based single-cell lineage tracing approach to study the metastasis rate and route of breast cancer cells and their interactions with the tumor microenvironment (TME) during metastasis. …”
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Efficacy of human heparin-binding EGF-like growth factor in healing experimental chemical burns by L. M. Dronko, T. M. Lutsenko, O. I. Golembiovska, T. Yu. Trokhymchuk, M. A. Arkhypova, V. A. Dibrova, Yu. V. Dibrova, S. L. Rybalko, S. A. Myakushko, A. A. Siromolot, O. Yu. Galkin

“…The preparations (100 μl, 1.5 mg of rhHB-EGF) were applied to burn wounds daily for 5 days. Wound area, healing rate and histological patterns of skin samples were estimated. …”
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Artificial slope deformation monitoring and analyzing based on SBAS technology by Xiaochuan Huang, Xiaochuan Huang, Xiaochuan Huang, Jincang Liu, Jincang Liu, Jincang Liu, Ting Yang, Ting Yang, Ting Yang, Yun Li, Yun Li, Yun Li, Lipeng Zhou, Lipeng Zhou, Lipeng Zhou

“…To address this gap, we employed the SBAS-InSAR methodology to analyze 44 Sentinel-1 SAR images spanning a highway slope region in Foshan City, Guangdong Province, integrating the slope’s construction timeline to temporally dissect deformation patterns and assess geological risks. Our results revealed a maximum annual average settlement rate of −35.69 mm/yr and a peak cumulative settlement of −28.9 mm, with deformation trends strongly correlated to construction phases—primarily concentrated between April 2022 and March 2023. …”
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Induction of reproduction of fish Anasa Nomorhampus sp. endemic Palu, Central Sulawesi orally through hormon bioencapsulation use Chironomus sp. by Dinda Wahyu Rezki, Agus Oman Sudrajat, Dinar Tri Soelistyowati, Odang Carman

“…This research focuses on assessing specific weight growth rate (LPBS), specific length growth rate (LPPS), survival rate (TKH), gonadosomatic index (IGS), gonadal histology, birth frequency, number of births, and growth performance. …”
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Spatiotemporal dynamics and key climatic influences on vegetation resilience in opencast coal mine dumps after restoration by Hui Wang, Chengye Zhang, Yaxin Ding, Feiyue Li, Wanxi Liu, Yan Ma, Yingjie Guo, Bikram Banerjee, Jun Li

“…These findings demonstrate that vegetation resilience captures stage-specific ecological patterns that NDVI alone cannot detect, thereby supporting adaptive restoration and climate-informed management in mining environments.…”
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Characteristics of second primary malignancies following bispecific antibodies therapy by Dan Liu, Tong Li, Liang Wang, Jia Guo, Xinyu Zhou, Hongsheng Zhou, Xiaojie Liang, Baiwei Luo, Bingyu Lin, WeiXiang Lu, Shengyu Tian, Zihong Cai, Zhihao Jin, Keren Chen

“…The incidence risk of SPMs was stable over the past 8 years, accounting for 1–2% of all adverse events, with a case fatality rate of 29.63% among the SPM cases. Myeloid leukemias and non-Hodgkin’s lymphoma were more frequent in blinatumomab recipients, while solid malignancies predominated in those treated with teclistamab. …”
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Analysis of epigenetic biomarkers for diagnosis and assessment of severity in rheumatoid arthritis: a cross-sectional study by Arkaitz Mucientes, Gracia María Martín Núñez, Natalia Mena-Vázquez, Jose Manuel Lisbona-Montañez, Sara Manrique-Arija, Andrés González-Jiménez, Patricia Ruiz-Limón, Aimara Garcia-Studer, Fernando Ortiz-Márquez, Laura Cano-García, Antonio Fernández-Nebro

“…This study aims to analyze methylation patterns in RA patients and controls to identify diagnostic and prognostic epigenetic biomarkers. …”
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GPC3: a novel mutated gene in pleuropulmonary blastoma by Jiahang Zeng, Xinying Wang, Yingyi Xu, Qinglin Yang, Junzheng Peng, Fenghua Wang, Jue Tang, Dongmei Huang, Jiachi Liao, Yunyu He, Lin Huang, Jianhua Liang, Le Li, Zefeng Lin

“…Survival analysis revealed that patients with high GPC3 expression (GPC3+++) exhibited a markedly lower two-year survival rate (30%) compared to moderate (GPC3++, 75%) and low (GPC3+, 90.9%) expression groups (p = 0.0035). …”
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Effects of licorice extract on Paraclostridium bifermentans spore growth and quality changes in ready-to-eat chicken breast during storage by Jichao Huang, Zimu Li, Mengmeng Song, Yang Lei, Kairan Sheng, Tianran Huang, Kaichen Zhang, Ming Huang

“…Furthermore, the Gompertz and Logistic models demonstrated a strong fit (R² > 0.98) with the growth patterns of P. bifermentans spores at 15, 20, and 25 °C. …”
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Multi-modal remote sensory learning for multi-objects over autonomous devices by Aysha Naseer, Naif Almudawi, Hanan Aljuaid, Abdulwahab Alazeb, Yahay AlQahtani, Asaad Algarni, Ahmad Jalal, Ahmad Jalal, Hui Liu, Hui Liu, Hui Liu

“…The assessment findings show a remarkable recognition rate of around 97.90% and 98.90%, on the AID and the UC Merced Land datasets, respectively.…”
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Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
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Spatial Heterogeneity of Bike-Sharing–Conventional Bus Intermodal Trip Distribution by Yang Chenyang, Tang Wenyun, Ma Jianxiao, Yin Chaoying, Wang Hanbin

“…The results indicated that the density of bike-sharing trips near bus stops followed a consistent pattern. The density decreases with increasing distance from the stop, and the rate of decline exhibits a "U-shaped" pattern. …”
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Systemic hormonal contraception and risk of venous thromboembolism by Oskari Heikinheimo, Elena Toffol, Timo Partonen, Anna But, Antti Latvala, Jari Haukka

“…This study aimed to assess the associations between the patterns of use of different systemic hormonal contraceptives and the risk of venous thromboembolism during 2017–2019. …”
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Effects of different exercise modalities on blood pressure and endothelial function in prehypertension individuals: a systematic review and network meta-analysis by Yingtian Yang, Qianyu Lv, Xinzheng Hou, Yanfei Lv, Xirui Zhang, Qian Wu, Xuejiao Ye, Chenyan Yang, Mingyu Huang, Shihan Wang

“…The surface underneath the cumulative ranking curve data was utilized to rate interventions. Confidence was evaluated using the CINeMA framework.ResultsA total of 18 articles with 2,592 individuals were included in the NMA. …”
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Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis by Takuya Murao, Gaifeng Ma, Atsushi Murao, Alok Jha, Jingsong Li, Yongchan Lee, Mian Zhou, Ping Wang, Ping Wang, Monowar Aziz, Monowar Aziz

“…Endogenous molecules released from stressed or damaged cells, known as damage-associated molecular patterns (DAMPs), exacerbate inflammation, organ injury, and mortality in sepsis. …”
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Climate change-induced shifts in landslide susceptibility in São Sebastião (southeastern Brazil) by Enner Alcântara, Cheila Flávia Baião, Yasmim Carvalho Guimarães, José Antonio Marengo, José Roberto Mantovani

“…Frequency Ratio (FR) analysis revealed varying levels of landslide susceptibility across scenarios, with RCP2.6 showing lower probabilities for moderate landslides (FR: 0.007946) compared to higher ratings for RCP4.5, RCP6.0, and RCP8.5 (FR: 1.663156 for high landslides). …”
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Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…Additionally, the study evaluates if acoustic and linguistic patterns can predict diagnostic group, as measured by the sensitivity, specificity, Cohen’s kappa and area under the receiver operating characteristic curve of the binary classifiers distinguishing each diagnostic group from each other. …”
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Prospective Study of the Association Between Frailty and Health Care Utilization in Patients With Advanced CKD by Alice L. Kennard, Alice M. Richardson, Suzanne Rainsford, Kelly L. Hamilton, Nicholas J. Glasgow, Kate L. Pumpa, Angela M. Douglas, Girish S. Talaulikar

“…Negative binomial regression was used to model health care utilization patterns. Frailty progression over study follow-up was described using Cox proportional hazards modelling. …”
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