Extreme Oncoplastic Surgery for Multifocal/Multicentric and Locally Advanced Breast Cancer by Chaitanyanand B. Koppiker, Aijaz Ul Noor, Santosh Dixit, Laleh Busheri, Gautam Sharan, Upendra Dhar, Hari Kiran Allampati, Smeeta Nare

“…EO followed by RT results in acceptable local-regional control, low rate of complications, and high patient satisfaction. …”
Get full text

Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy by Charles Ronsin, Pierre Braud, Christine Kandel-Aznar, Amaury Dujardin, Clémence Petit, David Larmet, Claire Garandeau, Clément Deltombe, Alice Le Clech, Claire Leman, Gilles Blancho, Juliet Schurder, Grégoire Couvrat-Desvergnes, Simon Ville

“…The cumulative mortality rate in cirrhosis-IgAN was 26% and 46% at 1-year and 3-years, respectively. …”
Get full text

The Stabilization Mechanism of a Stable Landslide Dam on the Eastern Margin of the Tibetan Plateau, China: Insights from Field Investigation and Numerical Simulation by Liang Song, Yanjun Shang, Yunsheng Wang, Tong Li, Zhuolin Xiao, Yuchao Zhao, Tao Tang, Shicheng Liu

“…Field investigation shows that the Conaxue Co landslide dam was formed by a high-speed long-runout landslide blocking the river, with its structure exhibiting a typical inverse grading pattern characterized by coarse-grained rock overlying fine-grained layers. …”
Get full text

Predictive value of D-Dimer and thromboplastin time as coagulation indicators for COVID-19 patients by Marwan Alshipli, Thamer A Altaim, Ammar A Oglat, Samira Ahmed Alsenany, Osama Khodrog, Hanan Hasan, Sally Mohammed Farghaly Abdelaliem, A Matrieh, Bassam Z Shakhreet, Riziq Allah Gaowgzeh

“…Our research found an abnormal pattern of coagulation disorders and COVID-19 severity that should be considered in the COVID-19 treatment protocol. …”
Get full text

Combined alverine citrate and simeticonein preparation in the treatment of irritable bowel syndrome by Ye. A. Poluektova, S. Yu. Kuchumova, V. T. Ivashkin

“…Thirteen patients had clinical pattern of diarrhea predominance (IBS-D), 17 – predominance of constipation (IBS-С). …”
Get full text

Kinetics of silicon extraction into alloy from a mixture of amorphous rocks by V.M. Shevko, N.M. Mirkayev, A.D. Badikova

“…The 50 % extraction of silicon into the alloy from the amorphous rocks is characterized by the apparent activation energy Eapp equal to 366.5 kJ, and for quartzite, this energy is higher and is 386 kJ. The similar pattern is observed for the period of inception of the process of silicon extraction into the alloy: Eapp for the amorphous rocks is 422 kJ, and 461 kJ for quartzite. …”
Get full text

Early Dynamics of Circulating Tumor DNA Following Curative Hypofractionated Radiotherapy Related to Disease Control in Lung Cancer by Kyungmi Yang, Jae Myoung Noh, Yeon Jeong Kim, Hongryull Pyo

“…The Dmax showed better disease control rate with marginal significance (<i>p</i> = 0.081). …”
Get full text

Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers by Sanjoy Das, Malay K. Das, Taison Jamatia, Nayan Ranjan Ghose Bishwas, Dhritiman Roy, Emdormi Rymbai

“…The amount of RSV released from FOL-RSV-LPHNCs was 96.53 ± 2.16% at pH 5.8 and 23.21 ± 2.01% at pH 7.4, indicative of a pH-responsive release pattern and good physiological stability. In vitro cytotoxicity study revealed that FOL-RSV-LPHNCs remarkably inhibited the viability of A549 cells and produced negligible toxic effect on Wi-38 healthy cells. …”
Get full text

Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis by Xinwan Zhang, Shijie Luo, Xiali Ye, Lin Liu, Xinxin Jia, Deyuan Jiang, Weiwei Wen

“…Compared to 0 mM Al treatment, low Al concentrations (0.4 mM) enhanced root vitality by 8.91%, while higher Al concentrations (10 and 100 mM) reduced root vigor by 19.31% and 76.81%, respectively. In a similar pattern, the electron transfer rate in leaves remained stable under low Al levels but significantly decreased under high Al conditions. …”
Get full text

Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa by Josephine Wambani, Patrick Okoth

“…However, in certain areas, the rate of decline has slowed or even reversed the gains made so far. …”
Get full text

Identification of endothelial INSR as an osteosarcoma-related biomarker and therapeutic target based on weighted gene co-expression network analysis by Xu Yingkai, Jiang Jianfeng, Hu Zhiyong, Zhou Zhifeng, Wang Lei

“…Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor characterized by a high rate of metastasis. The clinical efficacy of current targeted drugs for OS is limited, highlighting the urgent need to identify novel therapeutic targets. …”
Get full text

Dr Papineau Meets Dr Masquelet—Management of Open Calcaneal Fractures, Combining Two Techniques: A Case Report by Shuvendu P Roy, Yogendra Gupta, Gurinder Bedi, Vishwadeep Sharma

“…Aim and background: Open fractures of the calcaneum are often the source of significant morbidity due to the high rate of wound infection and significant morbidity, ranging from malunion to amputation. …”
Get full text

Fluid–solid coupling productivity analysis of multi-stage fractured horizontal wells in shale reservoirs by Qian QI, Ming YUE, Weiyao ZHU, Wenjiang MA

“…The simulation results of the model align with actual field data, showing that gas production follows an “L-shaped” decline pattern with a coincidence rate exceeding 70%, verifying the model’s accuracy.…”
Get full text

Safety and efficacy of prone position ventilation in patients with severe pneumonia in neurosurgical intensive care units by CHENG Longyang，LI Jun，LI Shaoya，LI Chuanqing，XU Manman，WANG Rong，ZHAO Penglai

“…PaO2 values followed a similar pattern：（79.63±4.81）mmHg，（89.90±6.83）mmHg，（106.98±12.26）mmHg，（130.40±12.03）mmHg and（135.68±13.95）mmHg，also demonstrating a significant increase（F=219.963，P<0.01）. …”
Get full text

Clinical characteristics and outcomes of non-tuberculous mycobacterial pulmonary infections after hematopoietic stem cell transplantation: A retrospective cohort study by Zahia Esber, Hamza Salam, Shefali Godara, Ayman Soubani

“…The most common radiologic pattern was nodular infiltrates in 15 (29.4%) patients. …”
Get full text

Cutis verticis gyrata in a Patient with Familial presenile sebaceous hyperplasia Presenting as &amp;ldquo;Leonine facies&amp;rdquo;: A Rare Case by Sutedja EK, Sutedja E, Ruchiatan K, Faldian Y, Yogya Y, Dwiyana RF, Maharani RH, Budiarsa M

“…Familial presenile sebaceous hyperplasia (FPSH), a rare variant of sebaceous hyperplasia, follows an autosomal dominant inheritance pattern with incomplete penetrance and variable severity among family members. …”
Get full text

Isokinetic knee strength as a predictor of cardiorespiratory responses during loaded aerobic capacity test in elite athletes by Bekir Çar, Ahmet Kurtoğlu, Özdemir Atar, Musa Türkmen, Özgür Eken, Mehmet Soyler, Monira I. Aldhahi

“…Cardiorespiratory parameters—average breath volume (ABV), average breath frequency (ABF), auxiliary oxygen density (AOD), and heart rate (HR)—were recorded during the Bruce Protocol conducted under two conditions: unloaded and with a 10 kg loaded vest. …”
Get full text

Neuroendocrine tumors of the digestive system: pathologic and molecular characteristics by V. V. Delektorskaya

“…In contrast, poorly differentiated neuroendocrine carcinomas have diffuse growth pattern, high-grade nuclear atypia and cellular proliferation, necrosis. …”
Get full text

Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations. by Wenhua Liang, Xuan Wu, Wenfeng Fang, Yuanyuan Zhao, Yunpeng Yang, Zhihuang Hu, Cong Xue, Jing Zhang, Jianwei Zhang, Yuxiang Ma, Ting Zhou, Yue Yan, Xue Hou, Tao Qin, Xiaoxiao Dinglin, Ying Tian, Peiyu Huang, Yan Huang, Hongyun Zhao, Li Zhang

“…Pooled data on objective response rate (ORR), progression free survival (PFS), overall survival (OS) were calculated. …”
Get full text

Demographic and clinical characteristics of patients with benign bone tumors: Evidence of bimodal age distribution in a Hispanic population by Blake C. Martin, Mohammad Khalil, Juan Lopez-Alvarenga, Michael Sander

“…This indicates an incidence rate of 0.00018 per person-year. The average age was 38.8 years (SD 24.0), with females representing 58 % of the sample. …”
Get full text