Clinical benefit of tafasitamab plus lenalidomide in relapsed or refractory diffuse large Bcell lymphoma: real-world data from the EarlyMIND study by Gabriel Brisou, Jérôme Paillassa, Sophie Bernard, Olivier Tournilhac, Luc-Matthieu Fornecker, Frédéric Maloisel, Lauris Gastaud, Eric Durot, Adrian Tempescul, Thorsten Braun, Vadim Ivanov, Brieuc Cherel, Caroline Serrier, Jeremy Delage, Abderrazak El Yamani, Baptiste Delapierre, Laure Lebras, Elsa Lestang, Camille Villesuzanne, Philippe Agape, Guillaume Escure, Ludovic Fouillet, Christophe Nicol, Gaëlle Olivier, Anthony Levy, Anne-Sophie Le Bris, Ophélie Cassuto, Laura Jacquemelle, Corinne Haioun, Charles Herbaux

“…Approval was based on the L-MIND study, which demonstrated a 57.5% overall response rate (ORR), 41.3% complete response (CR) rate, 12.1 months median progression-free survival (PFS), and 33.5 months median overall survival (OS) at five years. …”
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Neural signatures underlying the effect of social structure on empathy and altruistic behaviors by Xia Tian, Zixin Zheng, Renhui Li, Yue-Jia Luo, Chunliang Feng

“…Afterwards, participants rated the pain experienced by these innocents and shared money with other innocents. …”
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A mobile app to improve adherence to colorectal cancer screening and post polypectomy surveillance guidelines by María A. Casas, Francisco Schlottmann, Leandro Steinberg, Xavier Bessa, Anna Serradesanferm, Angels Pozo, Sonia Torres, Antoni Castells, Francesc Balaguer, Jaume Grau, Lisandro Pereyra, María Pellisé

“…Users’ characteristics, consultation types, and patient data were analyzed to assess app’s implementation, usage patterns, and impact on CRC screening and surveillance outcomes. …”
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Wastewater-based epidemiology of influenza A virus in Shenzhen: baseline values and implications for multi-pathogen surveillance by Xiuyuan Shi, Shisong Fang, Chen Du, Guixian Luo, Yanpeng Cheng, Zhen Zhang, Qiuying Lv, Xin Wang, Zhigao Chen, Bincai Wei, Ziqi Wu, Bingchan Guo, Panpan Yang, Miaomiao Luo, Weihua Wu, Liping Zhou, Ting Huang, Xuan Zou, Xiaolu Shi, Songzhe Fu, Zhanwei Du, Xinxin Han, Yinghui Li, Qinghua Hu

“…Influenza A virus (IAV) has become increasingly unpredictable in its seasonal patterns following the COVID-19 pandemic. A key challenge remains identifying optimal moments for public health interventions to inform evidence-based decisions. …”
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The diagnostic utility of lung ultrasound in the assessment of interstitial lung disease associated with rheumatoid arthritis by Shaoyu Zheng, Zexuan Zhou, Guangzhou Du, Qingzi Chen, Shaoqi Chen, Jianqun Lin, Shijian Hu, Weijin Zhang, Kedi Zheng, Jinghua Zhuang, Meigan Huang, Barbara Ruaro, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Marco Matucci-Cerinic, Daniel E. Furst, Yukai Wang

“…Sonographic ILD was detected in 76 patients who underwent LUS examination. The concordance rate between two modalities was 83.33% (Kappa value = 0.64, 95% CI 0.50–0.78). …”
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Analysis of HBV infection characteristics and OBI prevalence in pregnant women: a focus on HBcAb + alone or in combination with HBeAb + subgroups in Northwest China by Yun Xie, Ru Kang, Xiaoyue Cheng, Dan Li, Qi Wang, Jiao Li, Xuan Guo, Wenhui Gao, Xin He, Liutong Jiang, Gaili Meng

“…Abstract Background Hepatitis B virus (HBV) infection is a major global health concern. Serological patterns such as “HBeAb + and HBcAb+” or “HBcAb + only” are typically markers, which may represent either resolved infection or potential occult HBV infection (OBI) with risk of vertical transmission. …”
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The effect of photodynamic therapy on the wound process dynamics in patients with purulent hand diseases by J. L. Chepurnaya, G. G. Melkonyan, N. T. Gul’muradova, A. A. Sorokin

“…The analysis of cytological and morphological patterns also revealed an accelerated switch from the inflammatory stage of the wound process to the reparative one - the reparative processes in the PDT group began earlier by 2 days. …”
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Probabilistic seasonal dengue forecasting in Vietnam: A modelling study using superensembles. by Felipe J Colón-González, Leonardo Soares Bastos, Barbara Hofmann, Alison Hopkin, Quillon Harpham, Tom Crocker, Rosanna Amato, Iacopo Ferrario, Francesca Moschini, Samuel James, Sajni Malde, Eleanor Ainscoe, Vu Sinh Nam, Dang Quang Tan, Nguyen Duc Khoa, Mark Harrison, Gina Tsarouchi, Darren Lumbroso, Oliver J Brady, Rachel Lowe

“…As a climate-sensitive disease, environmental conditions and past patterns of dengue can be used to make predictions about future outbreak risk. …”
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Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…Deep learning (DL) offers a promising alternative for capturing nonlinear genetic relationships due to its ability to identify complex patterns without prior assumptions about the data structure. …”
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Population immunity to SARS-CoV-2 virus in residents of the Irkutsk Region in the dynamics of the epidemic by S. V. Balakhonov, V. I. Dubrovina, M. V. Chesnokova, D. D. Bryukhova, N. O. Kiseleva, A. B. Pyatidesyatnikova, K. M. Korytov, V. V. Voitkova, A. N. Perezhogin, T. A. Gavrilova, A. A. Seledtsov

“…In this regard, the study of the manifestations of the epidemic process of the new coronavirus infection COVID-19 and the patterns of its development are an urgent area of research. …”
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Groundwater rebound and seepage characteristics and water quality evolution in a sealed mining area in North China type coalfield by Huiyong YIN, Dehui SUN, Fangying DONG, Fanhua WANG, Lifeng ZHANG, Tao WU, Chao LIU, Yifan ZENG

“…After the goaf sealing, water-rock interactions persisted during the reinjection of the accumulated water, but the cation exchange rate slowed down. The mineral phases showed similar but weakened variation trends compared to the water inrush stage. …”
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Dynamics of changes in population immunity to the SARS-CоV-2 virus in residents the Irkutsk region in the context of the COVID-19 pandemic by S. V. Balakhonov, V. I. Dubrovina, A. B. Pyatidesyatnikova, D. D. Briukhova, N. O. Kiseleva, K. M. Korytov, V. V. Voitkova, A. N. Perezhogin, M. V. Chesnokova, T. A. Gavrilova, A. A. Seledtcov

“…A comprehensive study of the patterns of development and manifestations of the epidemic process of the new coronavirus infection COVID-19 is an urgent line of research. …”
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A first large study of whole-exome sequencing (WES) in 489 patients with suspected rare genetic disorders at a tertiary centre in Malaysia by Lip Hen Moey, Go Hun Seo, Boon Eu Cheah, Wee Teik Keng, Hane Lee, Gaik Siew Ch’ng

“…Introduction: Rare genetic disorders occur at a rate of 40–82 per 1000 live births worldwide. Identifying the molecular cause of rare genetic disorders is beneficial because it allows early diagnosis, facilitates treatment planning and provision of accurate genetic counselling. …”
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Effects of Dietary Schizochytrium Algae as ω-3 PUFA Source on the Egg-Laying Quail Performance, Serum Indexes, and Egg Yolk Fatty Acids Contents by Yifan Chang, Yue Xuan, Ruinan Zhang, Xuemei Ding, Qiufeng Zeng, Jianping Wang, Shiping Bai, Shanshan Li, Yan Liu, Yuchuan Chen, Keying Zhang

“…The objective of this experiment is to investigate the effects of SAP or SAO as ω-3 PUFA raw materials on production performance, egg quality, serum immunity, serum lipids, and fatty acid deposition patterns in the eggs of laying quails. Chinese yellow-feathered quails served as the experimental subjects. …”
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Skeletal muscle lncRNA profile associated with fatty acids in Nellore beef cattle by Bruna Maria Salatta, Maria Malane Magalhães Muniz, Larissa Fernanda Simielli Fonseca, Lucio Flavio Macedo Mota, Caio de Souza Teixeira, Gabriela Bonfá Frezarim, Marta Serna-García, Danielly Beraldo dos Santos Silva, Angélica Simone Cravo Pereira, Fernando Baldi, Lucia Galvão de Albuquerque

“…The K-means analysis was used to classify the 48 animals into three clusters based on their FA patterns. The C1 had significantly (p ≤ 0.05) higher PUFA, ω3, ω6, linoleic and α-linolenic content. …”
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The Role of Values and Emotions in Accepting Fake Political News in the Post-Truth Era by Amir Mollaee Mozaffari, Ali Ashraf Nazari

“…The interview data were analyzed using Discursive Psychology, focusing on the linguistic patterns and discourse structures in the participants' responses. …”
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Prevalence and characteristics of foreign body-induced upper gastrointestinal obstruction in dogs by Lalita Laiket, Wijit Sutthiprapa, Suchawalee Khattiya, Pimjai Temwichitr, Jatuporn Rattanasrisomporn, Naris Thengchaisri

“…Small-breed dogs were more likely to have foreign bodies in the esophagus, while larger dogs (medium and large breeds) were more likely to have them in the stomach (p < 0.001). Distinct material patterns emerged between the esophagus and stomach. …”
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Machine Learning Creates a Simple Endoscopic Classification System that Improves Dysplasia Detection in Barrett’s Oesophagus amongst Non-expert Endoscopists by Vinay Sehgal, Avi Rosenfeld, David G. Graham, Gideon Lipman, Raf Bisschops, Krish Ragunath, Manuel Rodriguez-Justo, Marco Novelli, Matthew R. Banks, Rehan J. Haidry, Laurence B. Lovat

“…In a blinded manner, videos were shown to 3 experts who were asked to interpret them based on their mucosal and microvasculature patterns and presence of nodularity and ulceration as well as overall suspected diagnosis. …”
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Results of a Multicenter Study on the Efficacy and Safety of Inosine Glycyl-Cysteinyl-Glutamate Disodium in the Treatment of Acute Ethanol Poisoning by I. A. Shikalova, A. N. Lodyagin, V. G. Antonov, A. Y. Simonova, N. B. Loginova, E. V. Baskakov, L. G. Zaitseva, V. V. Shilov, S. P. Katasonov

“…Comparative intergroup and intragroup analyses were carried out according to the main clinical, laboratory parameters and EEG monitoring data.Results The study showed a positive effect of the study drug — a reduction in the coma period was noted (from 137 (75; 180) minutes to 78 (50; 155) minutes (p<0.001)), higher values of the Glasgow-Pittsburgh scale were recorded after 3 and 6 hours from the start of the therapy (p<0.01), a reduction in the time of formation of EEG awakening patterns in patients with delta coma activity from 192.2 (161.9; 222.5) minutes to 112.5 (97.6; 127.6) minutes (p<0.001), a decrease in heart rate (p<0.02), a decrease in the number of complaints of weakness and dizziness (p<0.005), in patients with high ALT levels, the frequency of development and severity of tremor decreased (p<0.01). …”
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Prevalence and spatial distributions of trachomatous inflammation-follicular among children aged 1–9 years in rural areas of Yilmana Densa and Gonji Kolela districts, Northwestern... by Misganaw Alelign, Asmamaw Malede, Eshetu Shifaw, Tesfahun Taddege, Yideg Abinew, Metadel Adane

“…The Gi_Bin field was computed in hot spot spatial analysis, independent of the False Discovery Rate correction (FDR), to detect important hot spots and cold spots. …”
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