Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study by Ana Maria Meireles, Rita Calisto, Maria José Bento, Pedro Martinho Gouveia, Susana Bizarro, Manuel Teixeira, Cláudia Moreira, Ana Espírito Santo, Mário Mariz

“…Background: The chronic myeloid leukaemia population, treatment patterns and responses in Portugal are unknown. The aim of this study is to describe these features in a Portuguese reference centre. …”
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Sustainability and energy self-sufficiency; overcoming the barriers by Rania Abdel Galil

“…Renewable energy technologies are viewed as radical innovations which necessitate substantial changes in production and consumption patterns, hence often met with resistance from both institutions and individuals. …”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites by Tingwen He, Tingwen He, Tingwen He, Xiaolong Yuan, Liangjun Xiao, Tanggeran Hu, Yi Wang, Xiaolei Zhao, Xiaolei Zhao, Xiaolei Zhao, Lu Li, Lu Li, Chengbo Peng, Chengbo Peng, Chengbo Peng, Hongling Zhang, Hongling Zhang, Hongling Zhang, Yuan Zheng, Yuan Zheng, Yuan Zheng, Yuan Zheng

“…This study compared the metabolite profiles and gene expression patterns of the fruiting bodies of T. gaoligongensis with those of three types of cultivated mycelia. …”
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Mechanism of atrazine migration and diffusion control in soil by clay matrix composites by Xiangyu Wang, Qiang Fu, Tianxiao Li, Renjie Hou, Mo Li, Dong Liu, Fanying Kong, Mingxuan Liu, Shuqi Dong

“…In this study, three major problems of soil structure optimization, competitive adsorption enhancement and quantification of migration patterns in FC environments were solved through the preparation of clay-based composites (Sep/BC) combined with soil column simulation tests and isothermal adsorption tests. …”
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Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya by Edward K. Githinji, Lucy W. Irungu, Paul N. Ndegwa, Maxwell G. Machani, Richard O. Amito, Brigid J. Kemei, Paul N. Murima, Geoffrey M. Ombui, Antony K. Wanjoya, Charles M. Mbogo, Evan M. Mathenge

“…The study is aimed at determining species composition, levels of insecticide resistance, and knockdown patterns in Anopheles gambiae sensu lato in areas with and areas without insecticide resistance in Teso North and Teso South subcounties, Western Kenya. …”
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The Gaseous Blowout of the 30 Doradus Starburst Region in the LMC by Suraj Poudel, April Horton, Jo Vazquez, Kathleen A. Barger, Frances H. Cashman, Andrew J. Fox, Nicolas Lehner, Scott Lucchini, Dhanesh Krishnarao, N. M. McClure-Griffiths, Elena D’Onghia, Jason Tumlinson, Ananya Goon Tuli, Lauren Sdun, Stone Gebhart, Katherine Anthony, Bryce Cole, Jacco Th. van Loon, Julia Roman-Duval, Yik Ki Ma, Callum Lynn, Min-Young Lee, Denis Leahy

“…The metallicities and dust depletion patterns of the high-velocity absorbers at v _LSR  ≈ +120 km s ^−1 can be explained by either a foreground Milky Way (MW) halo cloud or an outflow from the LMC. …”
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Maternal asthma and newborn DNA methylation by Casper-Emil Tingskov Pedersen, Thanh T. Hoang, Jianping Jin, Anna Starnawska, Raquel Granell, Hannah R. Elliott, Anke Huels, Heather J. Zar, Dan J. Stein, Yining Zhang, Herman T. den Dekker, Liesbeth Duijts, Janine F. Felix, Júlia Sangüesa, Mariona Bustamante, Maribel Casas, Martine Vrijheid, Latha Kadalayil, Faisal I. Rezwan, Hasan Arshad, John W. Holloway, Stefan Röder, Ana C. Zenclussen, Gunda Herberth, Nicklas Heine Staunstrup, Henriette Thisted Horsdal, Jonathan Mill, Eilis Hannon, iPSYCH-MINERvA Group, Isabella Annesi-Maesano, Giancarlo Pesce, Nour Baïz, Barbara Heude, Sahra Hosseinian-Mohazzab, Carrie V. Breton, Sophia Harlid, Justin Harbs, Magnus Domellof, Christina West, Edwina Yeung, Xuehuo Zeng, Wenche Nystad, Siri E. Håberg, Maria C. Magnus, Diana Schendel, Stephanie J. London, Klaus Bønnelykke

“…Abstract Background Prenatal exposure to maternal asthma may influence DNA methylation patterns in offspring, potentially affecting their susceptibility to later diseases including asthma. …”
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Genetic evolution, epidemic trends, and recombination dynamics of PRRSV-1 in China by Chengzhen Weng, Chengzhen Weng, Chengzhen Weng, Xinxin Huang, Xinxin Huang, Xinxin Huang, Zhian Chen, Zhian Chen, Minjia He, Minjia He, Minjia He, Beiwen Zhang, Beiwen Zhang, Beiwen Zhang, Hongxi Li, Hongxi Li, Hongxi Li, Jingrui Xie, Jingrui Xie, Meichun Chen, Meichun Chen, Meichun Chen, Longxin Qiu, Longxin Qiu, Xiaobing Li, Xiaobing Li, Chong Cao, Chong Cao, Hongbo Chen, Hongbo Chen

“…This study systematically investigated the epidemiological patterns, genetic evolution, recombination dynamics, GP5 genetic diversity, and N-glycosylation variants of PRRSV-1 strains circulating in China. …”
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Risk of Incidence and Lethality by Etiology of Severe Acute Respiratory Syndrome in Hospitalized Children Under 1 Year of Age in Brazil in 2024: A Cross-Sectional Study by Tamires de Nazaré Soares, Natasha Cristina Oliveira Andrade, Suziane do Socorro dos Santos, Marcela Raíssa Asevedo Dergan, Karina Faine Freitas Takeda, Jully Greyce Freitas de Paula Ramalho, Luany Rafaele da Conceição Cruz, Perla Katheleen Valente Corrêa, Marli de Oliveira Almeida, Joyce dos Santos Freitas, Wilker Alves Silva, Marcos Jessé Abrahão Silva, Daniele Melo Sardinha, Luana Nepomuceno Gondim Costa Lima

“…Distribution by final classification and epidemiological week (EW) was analyzed; the incidence rate by Federative Unit (FU) (cases/100,000 < 1 year) with risk classification (Low/Moderate/High) was assessed; and, for cases with positive viral RT-PCR, the etiological frequency and virus-specific lethality rate (deaths/total cases of etiology ×100), also with risk classification, were extracted. …”
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Towards a theory of urban fragmentation: A cross-cultural analysis of fear, privatization, and the state by Setha Low

“…This paper employs a cross-cultural analysis to explore regional and national variations in residential gating and enclosure as a first step in developing an integrated theory of urban fragmentation. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…According to the first goal was rated the BP in the SLE patients during the period of 24 hours, for which: a) were examined the average daily, maximum and minimum levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), the average blood pressure; b) was analysed the daily index (DI) of SBP, DBP and the average blood pressure; c) was examined the time index (TI) of SBP, DBP and the average blood pressure. …”
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Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…Abstract Tryptophan decarboxylase (TDC) is the rate-limiting enzyme in the biosynthesis of melatonin and plays a crucial role in melatonin production in plants. …”
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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…By testing simulated SECM samples, the method demonstrated a substantial reduction in the false-negative rate even with up to 75% cumulus cell contamination. …”
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Trypanosoma dionisii in China: ecology and tentative epidemiology by Qin Liu, Mu-xin Chen, Yu-chun Cai, Yuan-yuan Li, Zi-yi Wang, Yun-hai Guo, Yu-wan Hao, Jing-bo Xue, Yi-dan Jing, Fan-na Wei, Yong-bin Wang, Yue-jin Li, Hai-fang Wang, Jun-ling Sun, Ya-li Wang, Gang Wang, Na Wang, Nai-li Guo, Jian-cun Fang, Wei-xiao Chen, Xun-ming Zhou, Yang Yu, Yi Zhang, Jun-hu Chen, Qiang Wang, Shi-zhu Li, Ge Yan, Qun Li

“…It is important to improve our understanding of ecological and epidemiological patterns to identify potential transmission vectors and to estimate the risk of T. dionisii infection in the local population as well as in various species of domestic and wild animals. …”
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Three-dimensional cell sheet model improves in vitro prediction accuracy of osteogenic potential for biodegradable magnesium-based metals by Liangwei Chen, Guanxi Wu, Siyu Liu, Ziyu Yan, Honglei Yue, Jianhua Zhu, Na Ge, Yifei Wang, Qingxiang Li, Guanqi Liu, Tingting Zhang, Haowen Zheng, Shaozhe Xin, Guangyunhao Sun, Chuanbin Guo, Jianmin Han

“…Flow cytometry showed higher Ki67 expression and lower ROS levels and apoptosis rate in cell sheets. ShRNA-mediated silencing of N-Cadherin in cell sheets significantly compromised their cytoprotective capacity against Mg metal-induced toxicity. …”
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Finger drawing on smartphone screens enables early Parkinson's disease detection through hybrid 1D-CNN and BiGRU deep learning architecture. by Zhaohui Zhu, E Wu, Pengfei Leng, Jiajun Sun, Mingming Ma, Zhigeng Pan

“…Our hybrid model combined multi-scale convolutional feature extraction (using parallel 1D-Convolutional branches) with bidirectional temporal pattern recognition (via gated recurrent unit [GRU] networks) to analyze movement abnormalities and detect the disease.…”
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Assessment of the functional state of left heart in patients with chronic heart failure with preserved ejection fraction by D. V. Vdovenko, R. A. Libis

“…All patients had the diastolic dysfunction: 60 patients had abnormal relaxation pattern, and 20 patients had pseudonormal pattern. …”
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Time-Series Forecasting Method Based on Hierarchical Spatio-Temporal Attention Mechanism by Zhiguo Xiao, Junli Liu, Xinyao Cao, Ke Wang, Dongni Li, Qian Liu

“…Breaking through traditional structural designs, the model employs a Squeeze-and-Excitation Network (SENet) to reconstruct the convolutional layers of the Temporal Convolutional Network (TCN), strengthening the feature expression of key time steps through dynamic channel weight allocation to address the redundancy issue of traditional causal convolutions in local pattern capture. A Bidirectional Gated Recurrent Unit (BiGRU) variant based on a global attention mechanism is designed, leveraging the collaboration between gating units and attention weights to mine cross-period long-distance dependencies and effectively alleviate the gradient disappearance problem of Recurrent Neural Network (RNN-like) models in multi-scale time-series analysis. …”
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Analysis of fibrous material deformation in the roll contact zone by Khurramov Shavkat, Abrorov Akbar, Abdullaev Akhror, Norov Nusiratjon, Baymatov Shakhriddin

“…The analytical description of the shape of contact curves and the thickness of processed material in the technological zone of a two-roll module in a dynamic mode is given, considering the deformation pattern of the processed material. It is determined that one of the factors that most influence the shape of the contact curve is the ratio of the compression rate of the coating deformation to the corresponding material feed rate. …”
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