Gas composition and pressure in the hypopharynx during high-flow oxygen therapy through a nasal cannula in healthy volunteers with different breathing patterns by Andrey I. Yaroshetskiy, Anna P. Krasnoshchekova, Fedor D. Tkachenko, Alina V. Rubashchenko, Daniil D. Zubarev, Vasiliy D. Konanykhin, Maxim I. Savelenok, Maxim M. Nosenko, Zamira M. Merzhoeva, Sergey N. Avdeev

“…Abstract Background High-flow nasal cannula is widespread in patients with hypoxemic and hypercapnic respiratory failure, but physiological data concerning influence of the combination of breathing pattern, preset flow rate (PFR), and inspiratory oxygen fraction (FDO2) on end-expiratory pressure (EEP), capnogram, oxygram, and exhaled tidal volume (VTe) remains insufficient. …”
Get full text

Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study by Carolyn E Schwartz, ScD, Katrina Borowiec, MA, Bruce D Rapkin, PhD, Joel A Finkelstein, MD, MSc, FRCS(C), Tai Sutherland, BA, Olivia B Caan, BA, MS, Richard L Skolasky, ScD

Get full text

Epidemiological Trends and Drug Resistance Patterns of Carbapenem-Resistant Gram-Negative Bacteria: A Retrospective Study in a Tertiary Hospital in China (2019-2024) by Hou B, Niu X, Yu Q, Wang W

“…In 2021, notable shifts in hospital infection control concerning CR-GNB were observed, with a reduction of over 40% in CRAB infection rates and a decline of over 35% in CRPA infection rates. …”
Get full text

Rethinking Radiation Therapy for Perineural Invasion in Oral Cancer: Does More Coverage Improve Outcomes? by Sarbani Ghosh Laskar, Anuj Kumar, Ashwini Adhau, Shwetabh Sinha, Samarpita Mohanty, Munita Bal, Neha Mittal, Swapnil Rane, Asawari Patil, Ashwini Budrukkar, Monali Swain, Pallavi Rane, Gouri Pantvaidya, Sudhir Nair, Deepa Nair, Anuja Deshmukh, Shivakumar Thiagarajan, Richa Vaish, Vidisha Tuljapurkar, Chandrashekhar Dravid, Poonam Joshi, Rathan Shetty, Arjun Singh, Pankaj Chaturvedi

“…All patients underwent surgery followed by adjuvant RT, with or without concurrent chemotherapy. Recurrence patterns were categorised as in‐field, marginal or out‐of‐field. …”
Get full text

Real-World Treatment Patterns and Survival Outcomes of Patients with Relapsed/Refractory Multiple Myeloma Treated with a Selinexor-Containing Triplet-Based Regimen by Andrew Whiteley, Stephen C. Ijioma, David Ray, Spencer S. Langerman, Ellen Hu, Amy Pierre, Tomer Mark, Habte Yimer

“…Previous clinical trials have demonstrated high rates of durable responses in the treatment of patients with triple-class-exposed RRMM with regimens containing selinexor, a first-in-class, orally available selective exportin 1 inhibitor. …”
Get full text

Prevalence and epidemiological pattern of drug-resistant tuberculosis among migrant populations in Wenzhou City, China, 2014–2023: implications for public health strategies by Lianpeng Wu, Lianpeng Wu, Xiyue Cai, Shuya Xu, Xuefeng Lin, Shuangliao Wu, Xueqin Xu, Xueqin Xu

Get full text

Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015–2018 by Danhui Mao, Junfang Mu, Yajing Li, Lu He, Qianhui Chai, Xin Zhao, Xiaojun Ren, Hui Cheng

“…Abstract Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mortality rates. Accurate identification of CMM patterns is crucial for CMM classification and health management. …”
Get full text

Global patterns and trends in ischemic stroke burden attributable to particulate matter pollution: changes from 1990 to 2021 and projections from 2022 to 2050 by Erman Wu, Erman Wu, Riqing Su, Tong Tang, Jiakun Li, Maimaitili Mijiti, Yandong Li, Gaocai Zhang, Minghao Lian, Yongtao Zhang, Guohua Zhu, Dangmurenjiafu Geng

Get full text

Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients. by Nathalie Conrad, Andrew Judge, Dexter Canoy, Jenny Tran, Johanna O'Donnell, Milad Nazarzadeh, Gholamreza Salimi-Khorshidi, F D Richard Hobbs, John G Cleland, John J V McMurray, Kazem Rahimi

“…Quality improvement efforts have been evaluated within individual clinical settings, but patterns of care across its continuum, although a critical component of chronic disease management, have not been studied. …”
Get full text

Incidence, Pattern and Mortality of Traumatic Abdominal Injury, a Three‐Year Study at the Largest Trauma Center in Southern Iran: A Cross‐Sectional Study by Mahnaz Yadollahi, Hosein Fazeli, Mehdi Ghasemian, Mohammad Reza Yousefi, Mehrdad Karajizadeh, Hanie Farajpour

Get full text

Opioid prescription patterns and pain severity among patients with opioid use disorder and other substance use disorders: a mixed methods study by Erin F. Madden, Gintare Daulys, Benjamin Tingey, Felicia Frabis, Pooja Lagisetty, Philip J. Kroth, Fares Qeadan

Get full text

Prevalence and patterns of multiple long-term conditions among lymphatic filariasis patients in Odisha, India: a community-based cross-sectional study by Abhinav Sinha, Prakash Kumar Sahoo, Krushna Chandra Sahoo, Patrick Highton, Shubhashisha Mohanty, Trupti Nayak, Akshya Kumar Prusty, Sujata Choudhury, Barsha Kumari, Karl Puchner, Kamlesh Khunti, Sanghamitra Pati

“…We estimated the prevalence and correlates of MLTC, assessed the commonly occurring patterns, and investigated the association between self-rated health (SRH) and the number of chronic conditions among patients with lymphatic filariasis. …”
Get full text

Future perspective of China's feed demand and supply during its fast transition period of food consumption by Wan-lu DONG, Xiao-bing WANG, Jun YANG

“…China has experienced dramatic changes in food consumption patterns over the last three decades. However, there are different opinions regarding the future trends in consumption. …”
Get full text

Abemaciclib treatment patterns and outcome in HR+/HER2- locally advanced or metastatic breast cancer: a real-world study from Kuwait and Lebanon by Anwar Al Nouri, Faisal Al Terkait, Nagi El Saghir, Hady Ghanem, Joseph Kattan, Cynthia Bishouti, Jade Dreyer, Soniya Rai, Alexandru Rosca

“…After three months of treatment, the rates of complete response (CR) and partial response (PR) as the best response were 6.9% and 63.8%, respectively, with an objective response rate (ORR) of 70.7%. …”
Get full text

Using Real World Evidence to Describe Pulmonary Arterial Hypertension Treatment Patterns, Healthcare Resource Utilization, and Costs Associated with PDE-5 Inhibitor Monotherapy by George Ruiz, Jason Yeaw, Cassandra A. Lickert, Ajita P. De, Rolin L. Wade, Janis Pruett, William Drake

“… # Results PDE-5i monotherapy for PAH treatment was associated with high treatment modification rates, low adherence, increased healthcare resource utilization, and high costs. …”
Get full text

Pattern and appropriateness of antibiotic therapy for acute respiratory tract infection among under-five children accessing care in a tertiary facility, Sokoto, Nigeria by Fatima Ishaq Abubakar, Hadiza Kubra Ahmed, Omotolani Olawunmi Akintunde, Idrees Abiodun Rufai

“…Introduction Acute respiratory tract infections (ARIs) are a major cause of antibiotic use among under-five (U5) children, often leading to inappropriate prescriptions that contribute to antimicrobial resistance, adverse drug reactions and higher healthcare costs.Objectives To assess the pattern and rate of antibiotic prescriptions and evaluate their appropriateness based on WHO and Paediatric Association of Nigeria guidelines for ARI treatment among U5 children at Usmanu Danfodiyo University Teaching Hospital, SokotoMethods A retrospective review of medical records (case folders and prescription sheets) was conducted for U5 children diagnosed with ARI over a 10-month period at the paediatric outpatient and inpatient units, Department of Paediatrics, UDUTH. …”
Get full text

Dispersal ability of Barbitistes vicetinus Galvagni & Fontana, 1993 (Orthoptera, Tettigoniidae) among different habitats including a morphometric analyses of the instars by G. Ortis, G. Cavaletto, L. Mazzon

“…However, movement rates were slightly higher within vineyards and changed depending on developmental stage. …”
Get full text

Vertical distribution, growth pattern, and age of an alien freshwater mussel, Sinanodonta pacifica, across elevations gradient on a tropical island and their implication for ecosys... by Asep Sahidin, Gunawan Muhammad, Pringgo Kusuma Dwi Noor Yadi Putra, Irfan Zidni, Zahidah Hasan, Bayu Kreshna Adhitya Sumarto, Septiana Sri Astuti, Yusli Wardiatno, Akira Komaru

“…Mussels were collected over one-year period (2020–2021) from lowland (0–300 m above sea level), midland (300–750 m), and highland (> 750 m) regions to examine density, age structure, growth pattern, and mortality. In midland, the highest population density 5.63 ± 1.83 individuals/m² and the fastest growth rate (growth coefficient, k = 0.26) was shown attributed to moderate temperatures, low suspended solids, and nutrient availability. …”
Get full text

Oral Candidiasis among Cancer Patients Attending a Tertiary Care Hospital in Chennai, South India: An Evaluation of Clinicomycological Association and Antifungal Susceptibility Pat... by Abirami Lakshmy Jayachandran, Radhika Katragadda, Ravinder Thyagarajan, Leela Vajravelu, Suganthi Manikesi, Shanmugam Kaliappan, Balaji Jayachandran

“…Fluconazole and Itraconazole showed an overall resistance rate of 14% and 14.8%, respectively. All the isolates were susceptible to Amphotericin B. …”
Get full text

Bacterial profile and antimicrobial susceptibility pattern of community and hospital-acquired urinary tract infections among UTI suspected geriatrics in Gondar town, Northwest Ethi... by Getachew Bitew Alebachew, Mulat Dagnew, Aklilu Ambachew, Belay Tessema

“…<h4>Conclusion</h4>This study found a high prevalence of bacterial UTI in geriatrics and a high rate of bacterial resistance was observed to most antimicrobial drugs tested. …”
Get full text