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4981
Development technologies and models of different types of gas reservoirs in Ordos Basin, NW China
Published 2025-06-01“…Four key directions of future research and technological breakthroughs are proposed: (1) Utilizing dual-porosity (fracture-matrix) modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones, supporting well pattern optimization and production enhancement of existing wells. (2) Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata, enhancing drilling success rates in low-permeability sandstone reservoirs. (3) Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally, achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs, and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization. (4) Further strengthening the evaluation of deep coal-rock gas in terms of resource potential, well type and pattern, reservoir stimulation, single-well performance, and economic viability.…”
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4982
Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease
Published 2024-11-01“…Defective DNA had a similar biphasic pattern, but data were more variable. Predicted intact and defective decay rates were faster for PLWH with earlier timing of ART initiation, higher initial CD4 + T cell count, and lower pre-ART viral load. …”
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4983
Dynamics of cerebral blood flow following sertraline treatment in adolescent depression
Published 2025-07-01“…Furthermore, Pearson correlation analysis was employed to examine associations between changes in regional CBF and clinical improvement, as measured by changes in the 17-item Hamilton Depression Rating Scale (HAMD-17) scores.ResultsAt baseline, adolescents with depression exhibited increased CBF in the posterior cuneus and decreased CBF in the middle temporal gyrus (MTG), right middle orbitofrontal gyrus, and the left middle frontal gyrus (MFG), compared to healthy controls. …”
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4984
Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform
Published 2025-04-01“…Quality findings from the early-stage, interim-stage, and conclusion-stage QC rounds of clinical trials were rated by using 3 severity grades (minor, major, or critical) and classified into 5 categories (with 4 taxonomy levels under each category). …”
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4985
Criminal legal penalties, substance use, and overdose: a concept mapping study examining Colorado’s criminal legal penalties
Published 2025-01-01“…Participants — recruited from community-based organizations — identified, rated, sorted, and categorized factors affecting criminal legal involvement, substance use, and/or overdose in their community. …”
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4986
Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia
Published 2016-02-01“…Depression severity was assessed using the 16-item Quick Inventory of Depressive Symptomatology-Self Report. PPS were rated using the modified Somatic Symptom Inventory. …”
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4987
Burden of six common sexually transmitted infections groups in North Africa and Middle East Region from 1990 to 2021: A systematic analysis of global burden of diseases
Published 2025-07-01“…Both age-standardized rates (ASRs) and total numbers were evaluated across 21 NAME countries, with breakdowns by sex, age, and sociodemographic index (SDI). …”
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4988
Googling Patients
Published 2022-11-01“…Numerous wearable devices collect data on consumers’ heart rates, exercise patterns and sleep patterns. In-home smart devices can track when users are active and what they are doing in their homes. …”
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4989
Neural signatures underlying the effect of social structure on empathy and altruistic behaviors
Published 2025-07-01“…Afterwards, participants rated the pain experienced by these innocents and shared money with other innocents. …”
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4990
Dietary inflammatory index and mortality in middle-aged and elderly patients with metabolic syndrome
Published 2025-07-01“…KM survival curves showed that higher DII quartiles were associated with lower survival rates (Log-rank P < 0.05). Cox regression results indicated that each unit increase in DII was associated with a higher risk of all-cause mortality (HR = 1.052, 95% CI: 1.006-1.100, P = 0.026) and cardiovascular mortality (HR = 1.157, 95% CI: 1.076–1.244, P < 0.001). …”
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4991
Advanced lung cancer inflammation index and its predictive value for all-cause and cardiovascular mortality among osteoarthritis patients: a NHANES-based study from 2001 to 2018
Published 2025-05-01“…These methodological strategies ensured comprehensive exploration of the ALI-mortality link in OA patients while minimizing bias and enhancing generalizability.ResultsThis research delved into the health records of 2,133 individuals, revealing a notable connection: those with OA and higher ALI scores exhibited significantly lower rates of both overall and CVD-related fatalities. …”
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4992
Postoperative liver dysfunction in gastric cancer patients following early enhanced nutritional protocols: a retrospective observational study
Published 2025-08-01“…The incidence rates of Grade 1 or higher elevations were 51.8% for AST and 39.4% for ALT on POD 1, and 47.9% for AST and 42.0% for ALT on POD 7. …”
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4993
Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo
Published 2022-12-01“…., 2010) adapted for this experiment. Growth rates were controlled and intracranial xenografts were visualized using a high-resolution micro-CT system. …”
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4994
Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstiti...
Published 2019-01-01“…The overall response and disease control rates were 77.8% (95% CI, 40.0–97.2) and 88.9% (95% CI, 51.8–97.2), respectively. …”
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4995
Monolayer graphene/platinum-modified 3D origami microfluidic paper-based biosensor for smartphone-assisted biomarkers detection
Published 2025-07-01“…Key results: The optimized 10 mM G/Pt catalyst significantly improved reaction rates (18× faster), leading to a rapid detection time constant of 6.69 and 4.59 s for dopamine and NADH, respectively. …”
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4996
Prevalence and sequence of chronic conditions in older people with dementia: a multi-province, population-based cohort study
Published 2025-05-01“…MethodsWe analyzed data from the 2019 Canadian Community Health Survey on the self-rated ability of adults and youth (N = 60 643; 12+ years) to cope with unexpected or difficult problems and day-to-day demands along with three PMH outcomes: selfrated mental health (SRMH), happiness and life satisfaction. …”
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4997
Ultrahigh-throughput single-pixel complex-field microscopy with frequency-comb acousto-optic coherent encoding (FACE)
Published 2025-08-01“…However, limitations such as slow pattern projection rates and time-consuming reconstruction algorithms hinder its throughput for real-time imaging. …”
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4998
Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study
Published 2025-01-01“…The app received positive ratings, with a System Usability Scale score of 77.4 and a Customer Satisfaction Score of 86.6%. …”
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4999
MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma
Published 2025-07-01“…CSS was significantly reduced in the “HIGH” than in the “LOW” group with respective 5-year survival rates: 78.7% (CI 95: 64.8–95.5) and 95.5% (CI 95 87.1–100.0) (Hazard Ratio: 7.4 (CI 95: 1.9–29.9, p = 0.027*) in multivariate analysis, including pathological classification, tumor size, International Society of Urological Pathology grade, lymphovascular invasion, dedifferentiated pattern, necrosis and adjuvant therapy. …”
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5000
Progressive subcortical involvement as spinocerebellar ataxia type 3 advances
Published 2025-06-01“…Moreover, the localized shape changes of subcortical structures correlated bidirectionally with clinical measurements including the length of CAG repeats within the ATXN3 gene, the scores on the scale of the assessment, the rating of ataxia, the instrumental activities of daily living scale, and the mini-mental state examination. …”
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