L-shaped association between dietary niacin intake and chronic kidney disease among adults in the USA: a cross-sectional study by Qishu Li, Wei Lan

“…CKD was determined by an estimated glomerular filtration rate (eGFR) (<60 ml/min/1.73 m2) or a urinary albumin-to-creatinine ratio (ACR) (≥30mg/g). …”
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Comparison of Different Ultrasound Protocols in Patients with Inflammatory Polyneuropathies with Practical Insights by Evelina Grusauskiene, Agne Smigelskyte, Erisela Qerama, Daiva Rastenyte

“…When the adjusted EAN/PNS protocol was applied, the detection rate rose to 100%, with a sensitivity of 100%. Both the adjusted BUS/NUP and UPSS protocols demonstrated a specificity of 90% in diagnosing CIDP. …”
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Evaluation of Cerebrospinal Fluid Pressure by a Formula and Its Role in the Pathogenesis of Glaucoma by Laura Landi, Federica Casciaro, Serena Telani, Carlo E. Traverso, Alon Harris, Alice C. Verticchio Vercellin, Lauren Saint, Michele Iester

“…Weight and height were measured to calculate body mass index (BMI), along with blood pressure, heart rate, visual acuity, and IOP. Biometrics exam, corneal pachymetry, peripapillary retinal nerve fiber layer (RNFL) thickness, and macular thickness were assessed. …”
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Experimental study on nonlinear hygroscopic and strength behavior of mudstone under coupled temperature and humidity conditions for underground engineering by Weisheng Zhao, Lijun Han, Shuai Yan, Wei He

“…The results indicated that the equilibrium water content (EWC) exhibited a three-stage growth pattern with increasing humidity: rapid growth (0‒20% RH), slow growth (20‒60% RH), and accelerated growth (60‒100% RH), whereas it decreased with increasing temperature, although the rate of decrease slowed progressively. …”
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Elderly patients undergoing laparoscopic radical cystectomy benefit from dynamic D-dimer measurement in combination with vascular ultrasonography: reduction of VTE risk and improve... by Wenbo Gao, Haihong Ye, Yangkai Xu

“…The incidence of VTE event, major postoperative complications, major bleeding rate, and evaluation of activities of daily living within 30 days postoperatively were compared.ResultsThe preoperative and intraoperative parameters were similar between the two groups. …”
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Impact of Caspase3/GSDME-Mediated Pyroptosis on Tumor Immune Microenvironment and Clinical Prognosis Across Multiple Cancers by Huang Y, Liu J, Lin C, Zhu Q, Wu L

“…Its uncontrolled growth pattern and metastasis characteristics are the fundamental reasons for the high mortality rate of cancer and its current incurability. …”
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IMPAIRED REGULATORY MECHANISMS OF THE mTOR SIGNALING PATHWAY IN OSTEOARTHROSIS by Elena Vasilyevna Chetina, E A Bratygina, E M Zaitseva, E P Sharapova, A L Alekseyeva, N V Demin, S A Makarov

“…Objective: to study the pattern of impaired regulatory mechanisms of the mammalian target of rapamycin (TOR) signaling pathway, by monitoring gene expression in the blood of patients with osteoarthrosis (OA) at different stages of the disease. …”
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Etiology, antibiotic susceptibility and prognostic factors of pediatric community-acquired sepsis in Addis Ababa, Ethiopia by Abel Abera Negash, Daniel Asrat, Workeabeba Abebe, Tewodros Hailemariam, Andualem Wubete, Abraham Aseffa, Mario Vaneechoutte

“…We sought to determine the etiology, role of Streptococcus pneumoniae, antibiotic susceptibility pattern, and prognostic factors in children with CAS in Addis Ababa, Ethiopia. …”
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Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study by Zhigang Xu, Baohong Xu

“…Results The study involved 2,090 critically ill liver cirrhosis patients, averaging 59.1 years old, with 65% male and a 28-day post-ICU admission mortality rate of 29%. The AST/ALT ratio was linked to mortality risk (adjusted odds ratio (OR) 1.1, 95% confidence interval (CI) 1.0–1.2; p = 0.015), showing a nonlinear pattern with a critical point at 3.6. …”
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Advances in application of ultrasound in diagnosis of diabetic nephropathy by GUO Juan, YANG Zhifang, JI Ri

“…As the global incidence rate of diabetes continues to rise, the clinical diagnosis and treatment of DN have become increasingly critical. …”
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Hyper-induction of IL-6 after TLR1/2 stimulation in calves with bovine respiratory disease. by Cian Reid, John Donlon, Aude Remot, Emer Kennedy, Giovanna De Matteis, Cliona O'Farrelly, Conor McAloon, Kieran G Meade

“…ROC analysis identified this induced IL-6 response to TLR1/2 stimulation as a potential diagnostic for BRD with a 74% true positive and 5% false positive detection rate for an IL-6 concentration >1780pg/mL. Overall, these results show altered immune responses specifically upon TLR1/2 activation is associated with BRD pathology which may contribute to disease progression. …”
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Precision public health alliances as a model and method for community engagement by Margaret L. McGladrey, Mary Elizabeth Lacy, Kristen McQuerry, Rachel Hogg-Graham, Svetla Slavova, Emily R. Clear, Kory Heier, Caitline Phan, Megan Hall, Ryan Parker, Mindy Keeton, Jennifer Sword, Thomas Ard, Charbel Salem

“…In Fall 2024, UKKD and UKCPH developed a statistical analysis plan to examine the interplay of social, geographic, and clinical factors associated with CRC screening rates, which is a UKKD quality improvement priority. …”
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A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution by Elishama N. Kanu, Ashley A. Fletcher, Jiayin Bao, Ethan S. Agritelley, Julia Button, Austin M. Eckhoff, Karrie Comatas, Tao Wang, Bin-Jin Hwang, Michael E. Lidsky, Sabino Zani, Dan G. Blazer, Peter J. Allen, Zhicheng Ji, Frank J. Lowery, Sri Krishna, Nicholas D. Klemen, Daniel P. Nussbaum, Erika J. Crosby

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by exceedingly high rates of metastatic progression, with the liver representing the most common site of distant spread. …”
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Quality of life and clinical data in hemodialysis patients with different degrees of pruritus by Sebastián Mas Fontao, Paula Manso, Julia Audije-Gil, David Hernán Gascueña, Fabiola Dapena, Nuria Aresté, Emilio Sánchez-Álvarez, Pablo Molina, Raquel Ojeda, Marian Goicoechea, Vicent Esteve Simó, Guillermo Alcalde Bezhold, Mario Prieto-Velasco, María Jesús Lloret, Ana Blanco Santos, Juan Manuel Buades, Carlos Narváez, Rafael Sánchez-Villanueva, Rosa Elena Pérez-Morales, María Dolores Arenas Jiménez, Fundación Renal Española Working Group, Prurito Working Group

“…Concerning other variables and symptoms associated with QoL, pruritus group exhibited higher rates of anxiety, depression, decreased sexual desire and sexual function, and sometimes to most of the time reported sleep onset problems, sleeping pill use, and drowsiness on waking (p < 0.001 in all cases). …”
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Construction of high-density bin genetic map and QTL mapping of fruit aroma in longan (Dimocarpus longan Lour.) by Wenshun Hu, Qing Zhang, Chaojun Deng, Qizhi Xu, Jimou Jiang, Xiuping Chen, Jianguo Li, Jisen Zhang, Shaoquan Zheng

“…These QTLs explained 19.8%–51.0% of the phenotypic variation rates and were distributed across 11 linkage groups, with two QTL-rich regions on LG7 and LG8. …”
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Dynamic immune response to Avian Pathogenic Escherichia coli infection in broiler chickens: Insights into pro-inflammatory and anti-inflammatory cytokine regulation by Xin Ye, Chuan-Yu Hsu, Linan Jia, Xue Zhang, Christopher Magee, Stephanie Whitham, Spencer Leigh, Jeffrey D. Evans, Li Zhang, Kelsy Robinson

“…This study investigates the dynamic immune responses to APEC infection in broiler chickens, with a focus on survival rates, airsac lesion scores, and cytokine gene expression patterns in lung tissue. …”
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Impact of Hepatic Steatosis on the Antiviral Effects of PEG-IFNα-2a in Patients with Chronic Hepatitis B and the Associated Mechanism by Huiqing Liang, Yaoyu Liu, Xiaoqian Jiang, Xiaoting Zheng, Jinmo Tang, Jiaen Yang, Hongli Zhuang, Penghua Lai, Li Peng, Zhenying Guo, Shanshan Cai, Dan Luo, Lingxia Xu, Qianguo Mao, Shaodong Chen

“…After 48 weeks of treatment and 24 weeks of follow-up, the rates of CR, VR, and BR had gradually decreased, whereas the severity of hepatic steatosis had increased. …”
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Resistome and Phylogenomics of <i>Escherichia coli</i> Strains Obtained from Diverse Sources in Jimma, Ethiopia by Mulatu Gashaw, Esayas Kebede Gudina, Guenter Froeschl, Ralph Matar, Solomon Ali, Liegl Gabriele, Amelie Hohensee, Thomas Seeholzer, Arne Kroidl, Andreas Wieser

“…<b>Introduction</b>: In recent years, antimicrobial resistance (AMR) rates have increased significantly in bacterial pathogens, particularly extended beta-lactam resistance. …”
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Global, regional, and national burden and trends of HIV/AIDS among women of childbearing age from 1990 to 2021: results from Global Burden of Disease 2021 by Mingjie Tang, Mingjie Tang, Jun Shao, Yanjie Jiang, Yanjie Jiang, Yinghong Li, Shiwei Li, Yilin Song, Wenxuan Wu, Jiqin Tang, Zhaoming Chen

“…In 2021, the global age-standardized rates for incidence (ASIR), prevalence (ASPR), mortality (ASMR), and DALYs (ASDALYR) were 34.73 (95% uncertainty interval [UI]: 30.03 to 40.54) per 100,000, 830.87 (95% UI: 784.57 to 884.29) per 100,000, 13.39 (95% UI: 10.34 to 17.56) per 100,000, and 829.75 (95% UI: 658.24 to 1,063.9) per 100,000, respectively. …”
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Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report by Posite Charles M, Faustin TM, Woldemichael MA, Vargas Escalante E, Mohamud Snr MA, Laetitia FM, Moses A, Santos MB, Samuel T, Ali ZI, Olive MM, Maha AB, Baanitse J, Said M, Wabinga H, Rosales YD

“…Incidence varies globally, with lower rates in non-African populations (around 0.5 per million annually) compared to higher prevalence in Nigeria and South Africa, where Black populations show increased susceptibility. …”
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