Estimating the burden of disease attributable to non-assisted suicide in Switzerland from 2009 to 2021: a secondary data analysis by Annora Mack, Sarah Rajkumar, Jacob Kofler, Kaspar Wyss

“…The stark sex disparity in suicide rates further underscores the need for sex-sensitive approaches. …”
Get full text

Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals by Nancy E. Scott, Elizabeth Wash, Christopher Zajac, Serin E. Erayil, Susan E. Kline, Anna Selmecki

“…Phenotypic data, including patterns of antifungal drug resistance, are limited. …”
Get full text

Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study by Ana Maria Meireles, Rita Calisto, Maria José Bento, Pedro Martinho Gouveia, Susana Bizarro, Manuel Teixeira, Cláudia Moreira, Ana Espírito Santo, Mário Mariz

“…At three months, the early molecular response rate was 77 %. At 12 months of treatment, of the 67 patients with response evaluation, 93 % achieved complete cytogenetic response and 49 % major molecular response. …”
Get full text

Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites by Tingwen He, Tingwen He, Tingwen He, Xiaolong Yuan, Liangjun Xiao, Tanggeran Hu, Yi Wang, Xiaolei Zhao, Xiaolei Zhao, Xiaolei Zhao, Lu Li, Lu Li, Chengbo Peng, Chengbo Peng, Chengbo Peng, Hongling Zhang, Hongling Zhang, Hongling Zhang, Yuan Zheng, Yuan Zheng, Yuan Zheng, Yuan Zheng

“…In particular, the expression of TgHMGR was markedly higher in NZJB than in XZJB and DM, correlating with the elevated terpenoids and triterpenoids levels, suggesting that TgHMGR may act as a key rate-limiting enzyme in the terpenoid biosynthesis pathway of T. gaoligongensis. …”
Get full text

Assessment of the experimental infection by Echinostoma paraensei (Lie & Basch, 1967) (Trematoda: Echinostomatidae) in two Biomphalaria tenagophila (D’Orbigny, 1835) (Gastropoda: P... by Michele Maria Santos, Juberlan Silva Garcia, Raquel de Oliveira Simões, Samaly dos Santos Souza, Paulo Marcos Zech Coelho, Zilton de Araújo Andrade, Arnaldo Maldonado Júnior

“…A correlation between the number of miracidia and the infectivity rate of B. tenagophila (TAIM) was observed. There was no correlation between the number of miracidia used and the number of cercariae released for both B. tenagophila isolates. …”
Get full text

Análisis técnico-económico para selección de aspersores Technical and economical analysis for sprinkler selection by Eduardo A. Holzapfel, Ximena M. Pardo, Vital P. da S. Paz, Antonieta Rodrigues, Ximena C. Orrego, Marco A. Lopez

“…To accomplish this an analysis was performed of different factors such as rate of water application, available time for irrigation, wind velocity, distribution pattern and pressure. …”
Get full text

Varied Presentations and Clinical Outcomes of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposit: An Indian Series of Five Patients by Uttayan Chakrabarti, Manish Chaturvedy, Arghya Majumdar, Nitin Kumar Bajpai, Aasma Nalwa, Tapabrata Das, Arpit Agarwal, Rajesh Jhorawat

“…The mean estimated glomerular filtration rate at presentation was 34.6 ml/min/1.73 m2 with 60% patients presenting as RPRF, the mean proteinuria being 5.8 g/day. …”
Get full text

Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya by Edward K. Githinji, Lucy W. Irungu, Paul N. Ndegwa, Maxwell G. Machani, Richard O. Amito, Brigid J. Kemei, Paul N. Murima, Geoffrey M. Ombui, Antony K. Wanjoya, Charles M. Mbogo, Evan M. Mathenge

“…Indoor resting mosquitoes had 100% mortality rate after 24 h since exposure. Overall SS genotypic frequency in Teso North and Teso South subcounties was 79.4% against 13.7% homozygous LL genotype and 6.9% heterozygous LS genotype. …”
Get full text

Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline by Simon Wiegrebe, Mathias Gorski, Janina M. Herold, Klaus J. Stark, Barbara Thorand, Christian Gieger, Carsten A. Böger, Johannes Schödel, Florian Hartig, Han Chen, Thomas W. Winkler, Helmut Küchenhoff, Iris M. Heid

“…We use longitudinal UK Biobank data for creatinine-based estimated glomerular filtration rate from 348,275 individuals to search for genetic variants associated with eGFR-decline. …”
Get full text

Optimizing jacket design for two-wheeler delivery workers during rainy conditions by Sujin Lim, Jisoo Ha

“…Also riders to make as many deliveries as possible and receive good ratings, most work more than 8 h. This complex work environment and long working hours expose them to physical fatigue, scrapes, bumps, falls, and other accidents, making it more necessary than ever to pay attention to the health and safety of delivery riders. …”
Get full text

Feasibility Assessment of an Optically Powered Digital Retinal Prosthesis Architecture for Retinal Ganglion Cell Stimulation by William Lemaire, Maher Benhouria, Konin Koua, Wei Tong, Gabriel Martin-Hardy, Melanie Stamp, Kumaravelu Ganesan, Louis-Philippe Gauthier, Marwan Besrour, Arman Ahnood, David John Garrett, Sebastien Roy, Michael R. Ibbotson, Steven Prawer, Rejean Fontaine

“…This confirms the feasibility of generating a response in RGCs with an infrared-powered digital architecture capable of delivering complex sequential stimulation patterns at high repetition rates, albeit with some limitations.…”
Get full text

IL‐38 attenuates myocardial ischemia–reperfusion injury by inhibiting macrophage inflammation by Yuzhen Wei, Junhui Xing, Xin Su, Xiangrao Li, Xiaofei Yan, Jiangtao Zhao, Hailong Tao

“…Cardiomyocytes cocultured with the supernatant of IL‐38‐ and troponin I‐treated macrophages showed a lower rate of apoptosis than controls. Conclusions IL‐38 attenuates MIRI by inhibiting macrophage inflammation. …”
Get full text

Association of Gait Characteristics and Depression in Patients with Parkinson’s Disease Assessed in Goal-Directed Locomotion Task by Péter Kincses, Norbert Kovács, Kázmér Karádi, Ádám Feldmann, Krisztina Dorn, Zsuzsanna Aschermann, Sámuel Komoly, Tibor Szolcsányi, Árpád Csathó, János Kállai

“…In patients with PD and depression, the visually deprived multitask augments the rate of cadence and diminishes stride length, while velocity remains relatively unchanged. …”
Get full text

Chronic Hepatitis C Therapy in Liver Cirrhosis Complicated by Telaprevir-Induced DRESS by Omar Y. S. Mousa, Rossa Khalaf, Rhonda L. Shannon, Chukwuma I. Egwim, Scott A. Zela, Victor Ankoma-Sey

“…Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare yet severe adverse drug-induced reaction with up to 10% mortality rate. Recent clinical trials reported an association between DRESS and telaprevir (TVR), an NS3/4A protease inhibitor of chronic hepatitis C (CHC) virus genotype 1. …”
Get full text

Applications of multispectral autofluorescence imaging of malignant tumors by G. V. Papayan, N. N. Petrishchev, S. V. Kim, Hyung Ho Kim, V. B. Berezin, Uk Kang

“…Among observed effects the new one is an unusually active angiogenesis at early stage of tumor formation accompanied by atypical tortuous vessels with growth rate up to 3 mm/day. Two-wave excitation simultaneous laser with excitation on wavelength of 390 nm and 635 nm is shown to be promising for autofluorescence diagnosis along with single-wave excitation which is conventionally performed in the violet-blue region of the spectrum. …”
Get full text

Survival outcomes and prognostic impact of adjuvant chemotherapy in stage IB lung adenocarcinoma with cribriform component by Rongyang Li, Yu Zhang, Jianhao Qiu, Mingyang Zang, Zhenguo Sun

“…The results showed that both the 5-year overall survival (OS) rates (63.5% vs. 84.5%, P = 0.013) and 5-year recurrence-free survival (RFS) rates (58.7% vs. 77.7%, P = 0.033) for cribriform-positive patients were lower than those for cribriform-negative patients. …”
Get full text

Spatial attention-guided pre-trained networks for accurate identification of crop diseases by Satrughan Kumar, S. S. Aravinth, Sreedhar Kollem, Munish Kumar, Quadri Noorulhasan Naveed, Azath Mubarakali, Abhishek Bhattacherjee, Addisu Frinjo Emma

“…The proposed approach achieved an accuracy of 99.89% and a recall rate of 99.87%, demonstrating its suitability for crop classification with minimal computational overhead. …”
Get full text

Investigation of the prevalence of polycystic ovary syndrome in Hamedan province in 2021 by Fatemeh Asadi, Zahra Mahdavi Fakher, Motahareh Masoomi, Salman Khazaie

“…Menstrual irregularity, infertility rate, mean serum testosterone level, the prevalence of hyperlipidemia, mean LDL, and total serum cholesterol were significantly higher in the PCOS group (P<0.05). …”
Get full text

Experimental investigation and modeling of heat and moisture transfer beneath asphalt pavements under rainfall conditions by Weihang Hua, Long Jin, Miaomiao Bai, Huimei Zhang

“…Sensitivity analysis identified the surface wetting rate coefficient (β) and evaporation attenuation coefficient (γ) as dominant factors (F > 6.0). …”
Get full text

Compound Action Potential of Isolated Spinal Cord: A Biophysical Analysis to Address Activity of Individual Fibers Following Contusion Injury by I. Rad, K. Khodayari, S. Kouhzaei, H. Mobasheri

“…Compound action potential (CAP) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. These properties are measured using amplitude, latency and area under curve of CAPs recorded from spinal cord. …”
Get full text