Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Two gastrointestinal events occurred, including one Grade 3 diarrhea treated with GCs. The overall GC usage rate was 31.7% (13/41), with 76.9% administered for Grade ≥3 irAEs. …”
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Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Disease burden was high and decreasing in low SDI regions, but low and stable in high SDI regions. The Age-standardized rate(ASR)-Deaths correlated negatively with SDI. …”
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Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
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Prospective Study of the Association Between Frailty and Health Care Utilization in Patients With Advanced CKD by Alice L. Kennard, Alice M. Richardson, Suzanne Rainsford, Kelly L. Hamilton, Nicholas J. Glasgow, Kate L. Pumpa, Angela M. Douglas, Girish S. Talaulikar

“…Negative binomial regression was used to model health care utilization patterns. Frailty progression over study follow-up was described using Cox proportional hazards modelling. …”
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Multi-modal remote sensory learning for multi-objects over autonomous devices by Aysha Naseer, Naif Almudawi, Hanan Aljuaid, Abdulwahab Alazeb, Yahay AlQahtani, Asaad Algarni, Ahmad Jalal, Ahmad Jalal, Hui Liu, Hui Liu, Hui Liu

“…The assessment findings show a remarkable recognition rate of around 97.90% and 98.90%, on the AID and the UC Merced Land datasets, respectively.…”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
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Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
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Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
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Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Results Bacterial pathogens were isolated from 33 patients, representing an isolation rate of 22.1% (95% CI: 16.2–29.6%). Gram-negative bacteria (GNB) accounted for the majority of the isolates, 25/33 (75.8%), with Escherichia coli, 6/25 (24%) being the predominant species. …”
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Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen by Damien Gabriel, Julie Devos, Sandrine Chapuis, Alexandre Comte, Pierre-Edouard Billot

“…Heart rate increased with musical intensity in both conditions, while EEG data showed reduced arousal levels during the live performance, possibly reflecting deeper cognitive absorption. …”
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Impact of PM2.5 Exposure on Reproductive Health and Sperm Functions in Mice from a High-Pollution Industrial Environment by Fu-Jen Cheng, Chung-Shin Yuan, Xin Chen, Yu-Sheng Lin, Ping-Hsun Wu, Ping-Chi Hsu

“…Results Exposure to WS-PM2.5 and WI-PM2.5 reduced rates of normal sperm morphology, with each also presenting unique toxic effects. …”
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Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…Therefore, in this study, corrosion void formation and migration mechanism on a newly designed alloy (Ni–28Cr–13Al–5W-0.06B-0.005C) was investigated and the corrosion rate of the alloy was compared with that of Ni–20Cr alloy under simulated municipal solid waste (MSW) incineration conditions at 600 °C. …”
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Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection by Qingze Gu, Kevin Yuan, Jia Wei, Chang Ho Yoon, Anders Skyrud Danielsen, Augustine Luk, David W. Eyre, A. Sarah Walker

“…Here we investigated the association between serial CRP percentile changes, antibiotic prescribing patterns, and patient outcomes in a large cohort with suspected infection, acknowledging that CRP is one of multiple factors in clinical decision-making. …”
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Artificial slope deformation monitoring and analyzing based on SBAS technology by Xiaochuan Huang, Xiaochuan Huang, Xiaochuan Huang, Jincang Liu, Jincang Liu, Jincang Liu, Ting Yang, Ting Yang, Ting Yang, Yun Li, Yun Li, Yun Li, Lipeng Zhou, Lipeng Zhou, Lipeng Zhou

“…To address this gap, we employed the SBAS-InSAR methodology to analyze 44 Sentinel-1 SAR images spanning a highway slope region in Foshan City, Guangdong Province, integrating the slope’s construction timeline to temporally dissect deformation patterns and assess geological risks. Our results revealed a maximum annual average settlement rate of −35.69 mm/yr and a peak cumulative settlement of −28.9 mm, with deformation trends strongly correlated to construction phases—primarily concentrated between April 2022 and March 2023. …”
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Regional trends in perceptions of American Shoulder and Elbow Surgeons towards barriers to access for patients with Medicaid: limited perioperative service access, low patient enga... by Patrick Saunders, MD, Abhay Mathur, MD, Jordan Frausto, BA, Carlos D. Ramirez, BS, Adam Z. Khan, MD, Brad Bushnell, MD, Hafiz F. Kassam, MD

“…Results: A total of 257 (18.5% response rate) ASES members completed the survey. The mean year in practice for respondents was 14. …”
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Predominance of gram-negative multidrug-resistant pathogens causing lower respiratory tract infections among gene X-pert negative presumptive tuberculosis patients in Dar Es Salaam... by Irene Rabiel, Mtebe Majigo, Loveness Urio, Lilian Nkinda, Peter Richard Torokaa, Elieshiupendo M. Niccodem, Mabula Kasubi, Doreen Kamori, Joel Manyahi, Agricola Joachim

“…MTB was detected only in high‑quality sputum samples. The high resistance rate to commonly prescribed antibiotics for LRTIs called for further large-scale studies to guide and/or refine treatment guidelines and optimize patient care.…”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
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Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches by Isabella D’Ambra, Isabella D’Ambra, Simona Saviano, Maria Assunta Ambrosio, Vincenzo Botte, Daniele Iudicone, Maria Grazia Mazzocchi, Louise Merquiol, Louise Merquiol, Louise Merquiol, Daniela Cianelli

“…Simulations indicated that surface circulation patterns promoted the permanence of medusae within the coastal area, particularly in summer. …”
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GPC3: a novel mutated gene in pleuropulmonary blastoma by Jiahang Zeng, Xinying Wang, Yingyi Xu, Qinglin Yang, Junzheng Peng, Fenghua Wang, Jue Tang, Dongmei Huang, Jiachi Liao, Yunyu He, Lin Huang, Jianhua Liang, Le Li, Zefeng Lin

“…Survival analysis revealed that patients with high GPC3 expression (GPC3+++) exhibited a markedly lower two-year survival rate (30%) compared to moderate (GPC3++, 75%) and low (GPC3+, 90.9%) expression groups (p = 0.0035). …”
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Recursive Class Connectivity Classification (R3C) Applied to Binary Image Segmentation for Improved Infant Fingerprint Enhancement by Joao Leonardo Harres Dall Agnol, Luiz Fernando Puttow Southier, Jefferson Tales Oliva, Marcelo Teixeira, Rodrigo Minetto, Marcelo Filipak, Dalcimar Casanova, Erick Oliveira Rodrigues

“…Consequently, identification rates for children remain significantly lower than those achieved with adult fingerprints. …”
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