Organisation of physical education in universities for students with disabilities: Modular approach by L. V. Zakharova, O. N. Moskovchenko, U. Solimene, N. V. Tretyakova, N. V. Bannikova, N. V. Lyulina, O. A. Kattsin

“…The evaluation of the validity of differences in the average values of the studied indicators was performed according to Student’s t-test at a significance level of 5%. The growth rates of indicators were calculated according to Brody’s formula.Results and scientific novelty. …”
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Fungi present distinguishable isotopic signals in their lipids when grown on glycolytic versus tricarboxylic acid cycle intermediates by S. Jabinski, S. Jabinski, V. Kučera, V. Kučera, M. Kopáček, M. Kopáček, J. Jansa, T. B. Meador, T. B. Meador, T. B. Meador

“…<p>Microbial activity in soils controls both the size and turnover rates of large carbon (<span class="inline-formula">C</span>) inventories stored in the subsurface, having important consequences for partitioning of <span class="inline-formula">C</span> between terrestrial and atmospheric reservoirs as well as recycling of mineral nutrients such as nitrogen or phosphorus (often bound to the <span class="inline-formula">C</span>) that support plant growth. …”
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Effect of transport stress on apoptosis and autophagy in goat lung cells by Yu Zhuo, Yunhai Hu, Yangshan Jin, Tian Ye, Yanzhen Yang, Ben Liu, Ben Liu, Ben Liu, Wenya Zheng, Wenya Zheng, Songlin Ding, Xue Yang, Xue Yang, Lucheng Zheng, Lucheng Zheng, Wei Hu, Wei Hu, Manxin Fang, Manxin Fang, Wanting Yi, Wenjing Xing

“…IntroductionRoad transportation exposes goats to thermal, mechanical, and microbial stressors that can compromise their welfare by triggering pulmonary apoptosis and autophagy processes associated with tissue damage and immunosuppression.MethodsTo explore potential biomarkers for transport-related welfare assessment, this study analyzed lung tissues from nine Ganxi goats (n = 9; 0 h control, 2 h/6 h transport groups) through an integrated experimental approach: TUNEL assays quantified apoptosis rates, immunohistochemistry mapped protein localization, Western blotting analyzed protein expression levels, and qPCR profiled gene expression of apoptotic regulators (Bax, Bcl-2) alongside autophagy-related markers (LC3B, p62, PINK1, Parkin).ResultsResults indicated time-dependent cellular stress patterns, where the 2 h group displayed elevated apoptosis rates, while the 6 h group exhibited upregulated Parkin expression (p &lt; 0.05) and altered regulation of apoptotic [Bcl-2-associated X-protein (Bax)/B-cell lymphoma-2 (Bcl-2)] and autophagy-related genes (Microtubule-associated protein 1 light chain 3B (LC3B), p62, PTEN-induced putative kinase 1 (PINK1)/Parkin). …”
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Bridging micro and macroevolution: insights from chromosomal dynamics in plants by Carmen Benítez-Benítez, Ashwini V. Mohan, Rogelio Sánchez-Villegas, Inés Gómez-Ramos, Ana Valdés-Florido, Kay Lucek, Marek Slovák, Marek Slovák, Filip Kolář, Filip Kolář, Ilia J. Leitch, Modesto Luceño, Isabel Larridon, Angelino Carta, Angelino Carta, Joan Cuscó-Borràs, Enrique Maguilla, Alegría Montero-Ramírez, Patrick G. Meirmans, Alison Dawn Scott, Santiago Martín-Bravo, Marcial Escudero

“…At the macroevolutionary level, we investigated the association between karyotype diversity and diversification rates using evidence from comparative genomics, chromosomal evolution modelling across phylogenies, and the association with several traits across different angiosperm lineages. …”
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Progressive subcortical involvement as spinocerebellar ataxia type 3 advances by Pubing Yuan, Yonghua Huang, Minghui Dai, Xin Jin, Dingxin Zheng, Die Xiao, Lihua Deng, Peiling Ou, Linfeng Shi, Yifan Chen, Jian Wang, Wei Chen, Yuanchao Zhang, Chen Liu

“…Abstract Background and objectives Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disease characterized by heterogeneous motor and nonmotor manifestations. The progressive pattern of subcortical shape abnormalities and their associations with the clinical phenotypes in SCA3 remain unknown. …”
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Characteristics of Anemia in Children Aged 6 Months to 5 Years Attending External Consultations at a Pediatric Hospital in Lisbon, Portugal by Réka Maulide Cane, Sérgio Chicumbe, Youssouf Keita, Anaxore Casimiro, Bárbara Martins Saraiva, Joana Vasconcelos, Beatriz Luzio Vaz, Afonso Sousa, Mafalda Cabral, Francisco Branco Caetano, Luís Varandas, Isabel Craveiro

“…Five children (6.8%) had normal hemoglobin but abnormal red-cell indices, with microcytic (60.0%; 3/5) or normocytic (40.0%; 2/5) patterns. Anemia rates were higher in males (55.1%), children aged 24–59 months, those residing in the Metropolitan Lisbon Area (82.6%), children whose caregivers had only basic or secondary education (58.0%), and those whose mothers were born in foreign countries (48.4%). …”
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Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…PDOs reproduced pathological and immunohistochemical patterns of source tumors, with pathogenic variants confirmed in 84% (21/25). …”
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WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer by Jing Lv, Jing Lv, Yuhua Zhou, Yuhua Zhou, Shengkai Jin, Shengkai Jin, Chaowei Fu, Chaowei Fu, Yang Shen, Yang Shen, Bo Liu, Bo Liu, Menglu Li, Yuwei Zhang, Yuwei Zhang, Ninghan Feng, Ninghan Feng, Ninghan Feng

“…BackgroundProstate cancer is one of the most common tumors in men, with its incidence and mortality rates continuing to rise year by year. Prostate-specific antigen (PSA) is the most commonly used screening indicator, but its lack of specificity leads to overdiagnosis and overtreatment. …”
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Burden of pulmonary arterial hypertension in Asia from 1990 to 2021: Findings from Global Burden of Disease Study 2021 by Shenshen Huang, Jiayong Qiu, Anyi Wang, Yuejiao Ma, Peiwen Wang, Dong Ding, Luhong Qiu, Shuangping Li, Mengyi Liu, Jiexin Zhang, Yimin Mao, Yi Yan, Xiqi Xu, Zhicheng Jing, Rongman Jia

“…Using the latest data from the Global Burden of Disease 2021, we evaluated and analyzed the distributions and patterns of PAH disease burden among various age groups, sexes, regions, and countries in Asia. …”
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Changing trends in oral mucosal diseases in China (2016–2024): a cross-sectional study of 316,166 patients with focus on COVID-19 impact and use of chinese patent medicines by Peiru Zhou, Xu Zhang, Yifan Chen, Jiakun Fang, Yanhong Meng, Furong Yang, Pan Wei, Hong Hua

“…Despite variations in prevalence rates of oral mucosal diseases across regions, previous studies often involved small sample sizes with insufficient data analysis. …”
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Comprehensive assessment of adverse event profiles associated with bispecific antibodies in multiple myeloma by Mobina Golmohammadi, Shahzad Raza, Maram Albayyadhi, Hossein Sholehrasa, Jack Khouri, Louis Williams, Doris K. Hansen, Azam Moradi, Xuan Xu, Moath Albliwi, Ali Hajj Ali, Danai Dima, Faiz Anwer, Barry Paul, Majid Jaberi-Douraki

“…GPRC5D/FcRH5 are associated with less grade 3/4 hematologic toxicity whereas BCMA BsAbs were associated with lower grade 3/4 CRS rates, compared to GPRC5D/FcRH5. These insights are crucial for guiding treatment decisions and developing strategies to improve patient outcomes.…”
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Effects of Live and Peptide-Based Antimicrobiota Vaccines on <i>Ixodes ricinus</i> Fitness, Microbiota, and Acquisition of Tick-Borne Pathogens by Apolline Maitre, Lourdes Mateos-Hernandez, Myriam Kratou, Natalia Egri, Jennifer Maye, Manel Juan, Adnan Hodžić, Dasiel Obregón, Lianet Abuin-Denis, Elianne Piloto-Sardinas, Andrea C. Fogaça, Alejandro Cabezas-Cruz

“…The vaccination altered the feeding patterns and fitness of the ticks, with the Live vaccine group showing a higher weight and faster feeding time. …”
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Effects of Regulated Deficit Irrigation on Leaf Nutrients, Enzyme Activities, and Root Zone Soil Nutrients during Fruit Expansion and Coloration-Sugar Accumulation Stages of Citrus... by ZHONG Yun, HUANG Zhikun, ZHU Shijiang, HAO Kun, ZHU Zirong, ZHANG Wei, CHEN Hongde

“…The aim was to explore the response patterns of soil nutrients, citrus leaf nutrients, antioxidant enzyme activities, and root-zone soil nutrients to water stress under drip irrigation across different growth stages. …”
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Effects of intravenous immunoglobulin on the negatively transformed subpopulations of neutrophilic granulocytes in newborns with congenital pneumonia and neonatal sepsis by I. V. Nesterova, S. V. Kovaleva, G. A. Chudilova, L. V. Lomtatidze, T. V. Smerchinskaya, V. N. Chapurina

“…Limitation of the negative NG transformation in their functionally significant subpopulations in newborns with CAP and NS was accompanied by positive clinical effects, i.e., optimization of antibiotic therapy, reduced duration of treatment, and improved mortality rates.…”
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Prevalence and determinants of hypertension in rwanda: a secondary data analysis using the WHO STEPS survey 2022 by Jean Damascene Hagenimana, Kagisha Divine Pascaline, Felix K. Rubuga, Kelly Mwiza, Sabine Musange F., Nathalie Umutoni, Caroline Mudereri, Jocelyne Uwitonze, Emmanuel Christian Nyabyenda, Piero I. Mazimpaka, Olivier N. Wane, Eric remera, Uwimana Aline, Marie Rosette NAHIMANA, Jeanine Condo, Gashaija Absolomon

“…The overall prevalence of hypertension was 16.8%, with higher rates observed among older individuals and those with obesity. …”
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Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

“…The inclusion of HCs provides evidence that rTMS-induced changes align with normative network patterns, and the responder analysis suggests that connectivity modulation is linked to clinical improvement. …”
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Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China by Qixia Luo, Mengru Chang, Ping Lu, Qian Guo, Xiaoqing Jiang, Tingting Xiao, Haoyu Zhang, Yingying Ma, Yan Zhang, Wei Yu, Erjia Zhang, Yunbo Chen, Ping Shen, Jinru Ji, Chaoqun Ying, Zhiying Liu, the BRICS Working Group, Huaiqiu Zhu, Yonghong Xiao

“…Abstract In recent decades, Acinetobacter baumannii has become a major global nosocomial pathogen, with bloodstream infections (BSIs) exhibiting mortality rates exceeding 60% and imposing substantial economic burdens. …”
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Characteristics and risk factors for outcomes in patients with Mycoplasma pneumoniae mono- and coinfections: A multicenter surveillance study in Wuhan, China, 2023 by Banghua Chen, Jie Pan, Ying Peng, Yuanyuan Zhang, Yunan Wan, Hongjie Wei, Kangguo Li, Wentao Song, Yunkang Zhao, Kang Fang, Huiming Ye, Jiali Cao, Jia Rui, Zeyu Zhao, Tianmu Chen

“…Children aged 1–10 years had the highest incidence, whereas those over 60 years had elevated hospitalization, severe infection, and fatality rates. Coinfection patterns differed by age, with bacterial-viral-Chlamydia pneumoniae (C. pneumoniae) / other pathogens prevalent in infants, bacterial-viral pathogens prevalent in preschoolers, and viral-viral pathogens prevalent in school-aged children. …”
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Human growth and development across time and space by Michael Hermanussen, Christiane Scheffler, Jana Fritsch, Piotr Fedurek, Joanna Nieczuja-Dwojacka, Maria Kaczmarek, Sylvia Kirchengast, Dominik Hagmann, Birgit Bühler, Katarzyna Górka, Sylwia Bartkowiak, Başak Koca Özer, Esin Köksal Babacan, Kübra Baran, Martin Musalek, Takashi Satake, Roshan Peiris, Toshie Hirohara, Komei Hattori, Natalia Nowak-Szczepanska, Anna Apanasewicz-Grzegorczyk, Aleksandra Gomula, Slawomir Koziel

“…Taking a decolonial view on the historical well-being of the Xavante, the overall health status of this Brazilian population has significantly worsened despite changes in the administrative frameworks, including reductions in mortality rates and increased hospital service usage. In addition to height, the alterations in body weight, the effects of fat mass on physical fitness, lifestyle, sports, and general health in Polish, Czech, and Turkish populations were discussed. …”
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Somatization symptoms and burnout: a correlational study among emergency nurses by Ningxiang Li, Ningxiang Li, Ningxiang Li, Nan Xie, Nan Xie, Nan Xie, Xiaoli Chen, Xiaoli Chen, Xiaoli Chen, Hao Zhang, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Dongmei Diao, Ling Zhu, Ling Zhu, Ling Zhu, Yue Zhou, Yue Zhou, Yue Zhou

“…To address this issue, healthcare management should consider implementing alternative shift patterns, optimizing workforce allocation, and revising compensation systems to ensure equitable labor distribution. …”
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