Extreme heat and pediatric health in a warming world: a space-time stratified case-crossover investigation in Ontario, Canada by Hallah Kassem, Eric Lavigne, Kate Weinberger, Michael Brauer

“…Conclusions In Ontario, EHEs decreased the rates of pediatric emergency healthcare utilization for injuries and increased the rates of respiratory illnesses, asthma, heat-related illnesses, heatstroke, dehydration, infectious and parasitic diseases, lower respiratory infections, and enteritis. …”
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SARS-CoV-2 Alchemy: Understanding the dynamics of age, vaccination, and geography in the evolution of SARS-CoV-2 in India. by Mansi Patel, Uzma Shamim, Umang Umang, Rajesh Pandey, Jitendra Narayan

“…Geographic analysis emphasizes notable regional variation in substitution rates, potentially driven by population density and local transmission dynamics, while regions with more homogeneous strain circulation show relatively lower substitution rates. …”
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Inequities in mortality and potential years of life lost (PYLL) in greater Santiago, Chile, during and after the COVID-19 pandemic by Claudio Vargas, Paola Salas, Felipe Elorrieta, Valentina Muñoz, Erika Vivanco, Matilde Maddaleno

“…Abstract Introduction In Chile and worldwide, disparities in age-adjusted mortality rates and Potential Years of Life Lost (PYLL) intensified during the initial two years of the COVID-19 pandemic, with low- and middle-income countries experiencing a disproportionate burden. …”
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Evaluating the effectiveness of the Drink Less smartphone app for reducing alcohol consumption compared with usual digital care: a comprehensive synopsis from a 6-month follow-up R... by Claire Garnett, Melissa Oldham, Gemma Loebenberg, Larisa Dinu, Emma Beard, Colin Angus, Robyn Burton, Matt Field, Felix Greaves, Matthew Hickman, Eileen Kaner, Susan Michie, Marcus Munafò, Elena Pizzo, Jamie Brown

“…Results The retention rate at 6-month follow-up was 80%. The data were not missing completely at random with differences detected in educational qualifications, occupation and income, indicating that multiple imputation was the most appropriate analytic approach. …”
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A test of ecophysiological theories on tropical forest functional traits along a VPD gradient by Huanyuan Zhang-Zheng, Yadvinder Malhi, Kasia Ziemińska, Agne Gvozdevaite, Theresa Peprah, Mickey Boakye, Stephen Adu-Bredu, Jesús Aguirre-Gutiérrez, Sam Moore, David Sandoval, Minxue Tang, Iain Colin Prentice, Imma Oliveras Menor

“…These patterns were associated with greater deciduousness, increased respiration rates and enhanced water transport at drier sites. …”
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Consensus guidelines for the management of intracranial ependymoma for low- and middle-income countries by Ahsan Ali Khan, Muhammad Usman Khalid, Mohammad Hamza Bajwa, Izza Tahir, Shahier Paracha, Muhammad Shakir, Bilal Mazhar Qureshi, Naureen Mushtaq, Ahmed Gilani, Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement), Syed Ather Enam.

“…Acknowledging the distinctepidemiological patterns of ependymomas, notably theirhigher incidence in paediatric patients, and variablesurvival rates, these guidelines emphasize tailoredmanagement approaches for different age groups. …”
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Effect of cholesterol on distribution, cell uptake, and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury by Lingyan Li, Xingjie Wu, Qianqian Guo, Yu'e Wang, Zhiyong He, Guangqiong Zhang, Shaobo Liu, Liping Shu, Babu Gajendran, Ying Chen, Xiangchun Shen, Ling Tao

“…Then, the slow cellular uptake rate observed for CH@LM contributed to a prolonged duration of drug efficacy. …”
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Design and Testing of Miniaturized Electrically Driven Plug Seedling Transplanter by Meng Chen, Yang Xu, Changjie Han, Desheng Li, Binning Yang, Shilong Qiu, Yan Luo, Hanping Mao, Xu Ma

“…In the field test, at three transplanting speeds of 80 plants/min, 100 plants/min, and 120 plants/min, the transplanting success rates were 94.17%, 90.83%, and 88.33%, respectively. …”
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Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…This study aimed to identify the gene expression patterns and biomarkers associated with breast cancer risk and progression by integrating transcriptomic and clinical data. …”
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Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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Multiple bursts of speciation in Madagascar’s endangered lemurs by Kathryn M. Everson, Luca Pozzi, Meredith A. Barrett, Mary E. Blair, Mariah E. Donohue, Peter M. Kappeler, Andrew C. Kitchener, Alan R. Lemmon, Emily Moriarty Lemmon, Carlos J. Pavón-Vázquez, Ute Radespiel, Blanchard Randrianambinina, Rodin M. Rasoloarison, Solofonirina Rasoloharijaona, Christian Roos, Jordi Salmona, Anne D. Yoder, Rosana Zenil-Ferguson, Dietmar Zinner, David W. Weisrock

“…Our analyses reveal multiple bursts of diversification (without subsequent declines) that explain much of today’s lemur diversity. We also find higher rates of speciation in Madagascar’s lemurs compared to lorisiforms, and we demonstrate that the lemur clades with high diversification rates also have high rates of genomic introgression. …”
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Identification of clusters related to programmed cell death and potential prognostic biomarkers for immunotherapy response in endometrial cancer by Shan Lu, Yiyun Wei, Liuyan Chen, Jinlian Cheng, Liuyan Qin, Xuemei Lu, Lihong Pang

“…Abstract Endometrial cancer (EC) is one of the few malignancies with increasing incidence and mortality rates. Targeted therapy and immunotherapy have become pivotal treatment strategies for EC patients. …”
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Analysis of common respiratory pathogens and epidemiological trends during peak influenza seasons in Tengzhou by Huiping Ma, Jinghai Hou, Jing Wang, Zhaolin Yuan, Sijin Man

“…Statistical analyses were performed to evaluate infection patterns and their associations with age and other variables. …”
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A four-year, mixed-family and community-based growth monitoring and promotion program using multi-level modeling to address undernutrition in children in Cambodia by Po-Yen Liu, Yen-Ting Lin, Yee-Hsuan Chiou, Maw-Sheng Lee

“…At baseline, children older than 12 months had significantly lower height-for-age (HAZ) and weight-for-age (WAZ) scores, as well as higher rates of stunting and wasting, compared to younger children. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…However, mark-release-recapture assessments suggest that male daily survival rates in the field may have been significantly impacted. …”
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Continuous aspirin treatment improves cardiovascular events and all-cause mortality in hemodialysis patients with peripheral artery disease by Chung-Kuan Wu, Noi Yar, Yun-Yi Chen

“…Kaplan–Meier analysis revealed that event-free rates of PTA, cardiovascular events, and all-cause mortality of patients with high MPR and continuous aspirin treatment were the highest among the three groups (p < 0.05).Conclusion Among HD patients with PAD, high MPR and continuous aspirin use significantly reduced the risk of PTA, surgical bypass, cardiovascular events, and all-cause mortality and improved the event-free rates of PTA, cardiovascular events, and all-cause mortality during long-term follow-up.…”
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Global burden and risk factors of childhood cardiovascular disease (1990–2021) by Caixia Hou, Nan Zhang, Chao Liu, Weijun Gao

“…Gender and age analyses revealed higher incidence and mortality rates among female children compared to males, with the 10–14 age group being the most affected. …”
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Artificial intelligence-based prediction of treatment failure and medication non-adherence in overactive bladder management by Mert Başaranoğlu, İsa Kamil Taşdemir, Erdem Akbay, Hasan Erdal Doruk

“…Key predictive factors included early changes in bladder wall thickness (OR: 3.82, 95% CI: 2.14–6.81), diabetes duration > 7 years (OR: 2.73, 95% CI: 1.58–4.72), and urgency improvement < 25% (OR: 2.94, 95% CI: 1.76–4.92). Treatment failure rates varied significantly among pathological subgroups, with highest rates in diabetic neuropathy (42.8%) and lowest in idiopathic OAB (28.6%, p = 0.024). …”
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Natural Occlusion-Based Backdoor Attacks: A Novel Approach to Compromising Pedestrian Detectors by Qiong Li, Yalun Wu, Qihuan Li, Xiaoshu Cui, Yuanwan Chen, Xiaolin Chang, Jiqiang Liu, Wenjia Niu

“…Through ablation studies, we further investigate the impact of key parameters such as trigger patterns and poisoning rates on attack effectiveness. …”
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Global, regional, and national burden of endocarditis, 1990−2021: a systematic analysis of the GBD 2021 study by Ji Feng, Peng Liu, Hailong Li, Hong Chen, Qiwei Shen, Hualong Liu, Jinzhu Hu

“…Its global epidemiological patterns and long-term trends have not been comprehensively characterized. …”
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