Differences in Kinematic and Muscle Activity Between ACL Injury Risk and Healthy Players in Female Football: Influence of Change of Direction Amplitude in a Cross-Sectional Case–Co... by Loreto Ferrández-Laliena, Lucía Vicente-Pina, Rocío Sánchez-Rodríguez, Graham J Chapman, Jose Heredia-Jimenez, César Hidalgo-García, José Miguel Tricás-Moreno, María Orosia Lucha-López

“…<i>Background and Objectives</i>: Anterior cruciate ligament (ACL) injury rates remain high and have a significant impact on female football players. …”
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Unmasking insider threats using a robust hybrid optimized generative pretrained neural network approach by P. Lavanya, H. Anila Glory, Manuj Aggarwal, V. S. Shankar Sriram

“…The structure of the proposed approach involves three phases: (1) Chebyshev Graph Laplacian Eigenmaps solver (CGLE) for selecting the user-designated samples by reducing the dimensionality of the data and Insider State clustering via Density-Based Spatial Clustering of Applications with Noise (IS-DBSCAN) (2) The EHI of multi-objective Bayesian optimization for optimizing the sensitive learning rate hyperparameter to ensure the stability of the Adabelief optimized WGAN and improve the quality of the generated adversarial samples. (3) The L2-SP regularization technique effectively fine-tunes the pretrained AGCN, which identifies the user behavioural pattern to detect the insiders. …”
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A STUDY TO ASSESS THE DISTRIBUTION OF SUSPECTED ADVERSE EVENTS FOLLOWING IMMUNISATION REPORTED IN A METROPOLITAN CITY IN INDIA by Sophie Simon, Shalini Rawat, Rohan Sangam, G D Velhal

“…Results: The AEFI reporting rate was calculated as 5.8 per 100000 doses administered per year. …”
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MODERN MOVEMENTS OF THE CRUST SURFACE IN GORNY ALTAI FROM GPS DATA by V. Yu. Timofeev, D. G. Ardyukov, A. V. Timofeev, E. V. Boiko

“…Analyzed are modern movements in the Gorny Altai region outside the Chuya earthquake area.The results of our study show that modern horizontal displacements occur in the NNW direction at the rate of 1.1 mm/yr, which is twice lower than the displacement rate before the earthquake.…”
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Optimization of bovine oocyte cryopreservation: membrane fusion competence and cell death of linoleic acid-in vitro matured oocytes subjected to vitrification by Glenda L. Ríos, María Florencia Suqueli García, María Florencia Suqueli García, Rodrigo J. Manrique, Jorgelina Buschiazzo

“…Zona pellucida-free oocytes co-incubated with sperm demonstrated that 43 μM LA better preserved the original sperm adhesion and fusion pattern post-vitrification, although fertilization rate was not improved. …”
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Dynamic brain-heart-gut coupling during sleep: a continuous physiological signal analysis by Guojing Wang, Guojing Wang, Guojing Wang, Hongyun Liu, Hongyun Liu, Shijing Wu, Shijing Wu, Xiaohua Yu, Xiaohua Yu, Weidong Wang, Weidong Wang

“…In terms of heart-gut coupling (HGC), the coupling strength between the very low frequency (VLF) band of heart rate variability (HRV) and all BS-derived power sequences was significantly lower than other HRV frequency bands. …”
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Aberrant Histone Methylation in Patients with Graves’ Disease by Ni Yan, Kaida Mu, Xiao-fei An, Ling Li, Qiu Qin, Rong-hua Song, Qiu-ming Yao, Xiao-qing Shao, Jin-an Zhang

“…The rate (degree) of H3K4 and H3K9 methylation and the expressions of histone-modifying genes were investigated. …”
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Red cell distribution width-to-platelet ratio (RPR) as a predictor of prolonged stay at hospital for COVID-19 inpatients by Martha Fors, Santiago J. Ballaz

“…One exemption was the red cell distribution width-to-platelet ratio (RPR) index, which can increase the probability of a longer hospital stay by up to ten times (HR(IC95%) = 0.092(0.03-0.29); p < 0.001).Conclusion The most effective biomarker to identify COVID-19 patients at high risk for extended hospital stay was RPR.Highlights IntroductionDetermining hospital Length of Stay (LoS) is vital for resource management, especially for future COVID-19 outbreaks.Previous studies have primarily focused on sociodemographic and clinical attributes, along with resource availability, but have not accounted for other factors like routine laboratory tests, which can significantly impact LoS predictions.This study examines novel hematology scores as predictors of LoS, emphasizing their importance in resource-limited settings like Ecuador.MethodsThis retrospective cohort study analyzed 2,930 COVID-19 patients admitted to Hospital IESS Quito Sur in Ecuador focusing on confirmed cases with complete blood count (CBC) values to assess LoS.The study explored various hematological ratios, such as the neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width-to-lymphocyte ratio (RLR), as potential predictors of LoS and in-hospital outcomes for COVID-19 patients, using a combination of univariate and multivariable Cox proportional hazards regression models.Kaplan-Meier survival estimates and log-rank tests were used to analyze survival and discharge probabilities over time, highlighting sex-dependent effects and the significant association between selected hematological indices and patient outcomes.ResultsThe mean LoS for survivors was significantly shorter compared to those who died (p < 0.001), indicating that longer hospitalization was associated with higher mortality risk.Women had a shorter average LoS (with lower mortality risk (p < 0.001), suggesting an asymmetrical hospitalization pattern based on sex.While most hematological markers had minimal clinical relevance for LoS, the red cell distribution width-to-platelet ratio (RPR) stood out, increasing the likelihood of a longer hospital stay by up to tenfold, making it a critical factor in predicting prolonged hospitalization.DiscussionMen had longer hospital stays and higher mortality rates than women, likely due to differing inflammatory responses, though hyperinflammation markers like NLR, PLR, and Leu-CPR had minimal clinical impact.RPR had the strongest link to longer hospital stays, indicating a higher risk of extended hospitalization in severe COVID-19 cases.Elevated RPR is tied to oxidative stress and coagulation issues, suggesting early identification could help reduce prolonged stays and complications.ConclusionResearch generally points to clinical complications from COVID-19 as the main factor behind prolonged hospitalizations, underlining the importance of early identification and management of these issues.…”
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A bibliometric analysis of research trends in mesenchymal stem cell therapy for neonatal bronchopulmonary dysplasia: 2004–2024 by Lu Bai, Yue Xin

“…Time-series analysis revealed a significant acceleration in publication output after 2015 (p &lt; 0.01), with a compound annual growth rate of 18.2%. The United States was the leading contributor (131 publications, 37.1%), followed by China (72 publications, 20.4%) and Canada (54 publications, 15.3%). …”
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Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial. by Xinlei Ma, Fan Yang, Jinzhi Wu, Bei Xu, Mengdi Jiang, Yiduo Sun, Chuanying Sun, Ye Yu, Danyi Xu, Lanlan Xiao, Chunyun Ren, Chunyan Chen, Zi Ye, Junyu Liang, Jin Lin, Weiqian Chen

“…Secondary endpoints: PMR-AS score, c-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) at weeks 12 and 24. Thirty-nine patients with newly diagnosed PMR received tofacitinib, and 37 patients received glucocorticoid. …”
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Estimation of duration and its changes in Lagrangian observations relying on ice floes in the Arctic Ocean utilizing a sea ice motion product by F. Zhang, F. Zhang, R. Lei, R. Lei, M. Qu, N. Li, Y. Chen, X. Pang

“…In particular, the autumn east–west surface air pressure gradient across the central Arctic and the Arctic dipole anomaly indices significantly influenced the terminal points of ice trajectories after 9 months, and their extreme positive phases were found to expand the ideal deployment areas. The rate of increase in near-surface air temperatures in autumn–spring along the trajectories was more pronounced in the TPD region than that in the BG region. …”
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Loss of Reduction in Pediatric Distal Radius Fractures: Risk Factors From a Prospective Multicenter Registry by Apurva S. Shah, MD, MBA, Zoe E. Belardo, BA, Mark L. Miller, MD, Michael C. Willey, MD, Susan T. Mahan, MD, MPH, Divya Talwar, PhD, MPH, Donald S. Bae, MD

“…The majority of subjects sustained bicortical metaphyseal distal radius fractures (68%), followed by Salter-Harris II physeal fractures (26%). The rate of radiographic LOR was 44% (271/616), and 11% (70/616) of fractures shifted ≥20°. …”
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Analysis of influencing factors for primary membranous nephropathy complicated with atherosclerotic cardiovascular disease and establishment of a nomogram prediction model by Mirixiatijiang· Maimaiti, Zhu Guo-qiang, Su Ming-jie, Halinuer· Shadekejiang, Zhang Xue-qin, Lu Chen

“…They also had significantly higher systolic blood pressure ［130（120， 142） mmHg（1 mmHg=0.133 kPa） <italic>vs</italic> 122.0（113.5， 135.5） mmHg］， higher diastolic blood pressure ［80 （75， 90） mmHg <italic>vs</italic> 80（70， 85.5） mmHg］， higher prevalence of hypertension［142（64.8%） <italic>vs</italic> 67 （32.7%）］， and higher proportion of manual workers［60（27.4%） <italic>vs</italic> 28（13.7%）］ Additionally， lymphocyte count （LYM）， platelet count （PLT）， blood sodium concentration （Na）， blood urea nitrogen （BUN）， blood creatinine （Cr）， estimated glomerular filtration rate （eGFR）， 24-hour quantitative urine protein， glutamic transaminase， urinary occult blood， number of urinary hyaline and pathological tubular patterns， C-reactive protein （CRP）， complement C4， plasma fibrinogen， D-dimer， and centrocyte-lymphocyte ratio were all significantly different between the two groups （<italic>P</italic>&lt;0.05）. …”
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A data-driven approach to forest health assessment through multivariate analysis and machine learning techniques by Raja Waqar Ahmed Khan, Hamayun Shaheen, Muhammad Ejaz Ul Islam Dar, Tariq Habib, Muhammad Manzoor, Syed Waseem Gillani, Abeer Al-Andal, John Oluwafemi Ayoola, Muhammad Waheed

“…RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health. …”
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Digital learning resource use among Swedish medical students: insights from a nationwide survey by Martin F. Bjurström, Emma Lundkvist, Louise W. Sturesson, Ola Borgquist, Robin Lundén, Malin Jonsson Fagerlund, Miklós Lipcsey, Thomas Kander

“…Results One thousand seven hundred sixty-six students responded to the survey, with an average response rate of 20.2% across sites. The five most frequently used digital resources were (percentage using at least on a weekly basis): University study platform (75.3%), videos (68.0%), flashcards (66.4%), student notes (53.4%) and external study platforms (47.3%). …”
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Citronella oil-loaded electro-spun single and core-shell nano fibers as sustained repellent systems against Aedes aegypti by Samali Udara Liyanaarachchi, Sanjeewa K. Rodrigo, Nilwala Kottegoda, Veranja Karunaratne, Menaka Hapugoda, Tharaka Ranathunge, Lahiru Udayanga, Dushmantha Adikari

“…It was found that maintaining the outer:inner flow rate ratio at 5:2 in coaxial process is imperative to produce good fibers. …”
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Spatio-temporal mapping reveals changes in soil organic carbon stocks across the contiguous United States since 1955 by Chenconghai Yang, Feixue Shen, Xiang Li, Wenkai Cui, Lei Zhang, Lin Yang, Chenghu Zhou

“…Abstract Understanding spatio-temporal patterns of soil organic carbon (SOC) is critical for global climate change mitigation and sustainable soil management. …”
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Effects of Hole Irrigation Device Parameters on Soil Water Characteristics Under Different Biogas Slurry Ratios by Peng Xiang, Jian Zheng, Yan Wang, You Wu

“…The lateral and vertical wetting front migration distances exhibited a well-defined power function relationship with the soil’s stable infiltration rate and infiltration time (<i>R</i>² ≥ 0.977). …”
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Assessment of predictors and mitigation strategy for therapeutic inertia in the management of hypertension: a quality improvement project by Ananyan Sampath, Shreya Deshpande, Rashmi Verma, Rajnish Joshi

“…When patient adherence was disregarded, TI increased to 49.7%. The total error rate in BP management ranged from 53.29% to 61.5%. …”
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Applying mortality data to improve emergency care planning for haemodialysis patients: a quality improvement project by Lisa Tang, Usha Appalsawmy

“…Cases involving cardiac arrest underwent further analysis, examining factors including their Clinical Frailty Score4 and the presence of a ReSPECT form.2 This review identified the underutilisation of ReSPECT forms in frail haemodialysis patients.Phase 2: we expanded the review of ReSPECT form use beyond cardiac arrest cases to include all haemodialysis patients who underwent an SJR in the same time frame, thus providing a broader perspective on ReSPECT form usage within the whole cohort.Phase 3: an intervention in the form of a departmental educational campaign, emphasising the high mortality rate among frail haemodialysis patients and, thus, the importance of advance care planning, was carried out. …”
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