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Real-World Treatment Patterns and Survival Outcomes of Patients with Relapsed/Refractory Multiple Myeloma Treated with a Selinexor-Containing Triplet-Based Regimen
Published 2025-05-01“…Previous clinical trials have demonstrated high rates of durable responses in the treatment of patients with triple-class-exposed RRMM with regimens containing selinexor, a first-in-class, orally available selective exportin 1 inhibitor. …”
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Rethinking Radiation Therapy for Perineural Invasion in Oral Cancer: Does More Coverage Improve Outcomes?
Published 2025-08-01“…All patients underwent surgery followed by adjuvant RT, with or without concurrent chemotherapy. Recurrence patterns were categorised as in‐field, marginal or out‐of‐field. …”
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Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015–2018
Published 2025-07-01“…Abstract Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mortality rates. Accurate identification of CMM patterns is crucial for CMM classification and health management. …”
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Epidemiological Trends and Drug Resistance Patterns of Carbapenem-Resistant Gram-Negative Bacteria: A Retrospective Study in a Tertiary Hospital in China (2019-2024)
Published 2025-06-01“…In 2021, notable shifts in hospital infection control concerning CR-GNB were observed, with a reduction of over 40% in CRAB infection rates and a decline of over 35% in CRPA infection rates. …”
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Dispersal ability of Barbitistes vicetinus Galvagni & Fontana, 1993 (Orthoptera, Tettigoniidae) among different habitats including a morphometric analyses of the instars
Published 2025-12-01“…However, movement rates were slightly higher within vineyards and changed depending on developmental stage. …”
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Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients.
Published 2019-05-01“…Quality improvement efforts have been evaluated within individual clinical settings, but patterns of care across its continuum, although a critical component of chronic disease management, have not been studied. …”
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Residential segregation and socio-spatial processes in Marseille. Urban social sustainability challenge
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892
FPGA Implementation for 24.576-Gbit/s Optical PAM4 Signal Transmission with MLP-Based Digital Pre-Distortion
Published 2024-12-01“…At the receiver, the parallel constant modulus algorithm (PCMA) was applied for signal processing. The bit error rate (BER) achieved met the 2.4 × 10<sup>−2</sup> threshold for soft-decision forward error correction (SD-FEC), enabling a net transmission bit rate of 24.576 Gbit/s. …”
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EEG–fNIRS signal integration for motor imagery classification using deep learning and evidence theory
Published 2025-09-01“…For EEG signals, spatiotemporal features are extracted using dual-scale temporal convolution and depthwise separable convolution, and a hybrid attention module is introduced to enhance the network's sensitivity to salient neural patterns. For fNIRS signals, spatial convolution across all channels is employed to explore activation differences among brain regions, and parallel temporal convolution combined with a gated recurrent unit (GRU) captures richer temporal dynamics of the hemodynamic response. …”
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Recurrence patterns and long-term survival of locally advanced esophageal cancer patients with pathological complete response after different neoadjuvant therapies followed by surg...
Published 2025-07-01“…Results Under multimodal neoadjuvant therapy, there was no significant difference in recurrence rates among the three groups (NAC: 5.88% vs. NICT: 7.14% vs. …”
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Using Real World Evidence to Describe Pulmonary Arterial Hypertension Treatment Patterns, Healthcare Resource Utilization, and Costs Associated with PDE-5 Inhibitor Monotherapy
Published 2018-01-01“… # Results PDE-5i monotherapy for PAH treatment was associated with high treatment modification rates, low adherence, increased healthcare resource utilization, and high costs. …”
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Gas composition and pressure in the hypopharynx during high-flow oxygen therapy through a nasal cannula in healthy volunteers with different breathing patterns
Published 2025-08-01“…Abstract Background High-flow nasal cannula is widespread in patients with hypoxemic and hypercapnic respiratory failure, but physiological data concerning influence of the combination of breathing pattern, preset flow rate (PFR), and inspiratory oxygen fraction (FDO2) on end-expiratory pressure (EEP), capnogram, oxygram, and exhaled tidal volume (VTe) remains insufficient. …”
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Abemaciclib treatment patterns and outcome in HR+/HER2- locally advanced or metastatic breast cancer: a real-world study from Kuwait and Lebanon
Published 2025-06-01“…After three months of treatment, the rates of complete response (CR) and partial response (PR) as the best response were 6.9% and 63.8%, respectively, with an objective response rate (ORR) of 70.7%. …”
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Clinical patterns and predictors of trauma-related mortality over 13 years: a retrospective analysis from a Level 1 National trauma center
Published 2025-07-01“…Pre-hospital deaths followed a similar pattern to the overall mortality, while the in-hospital rates remained steady. …”
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Identification and analysis of diverse programmed cell death patterns in idiopathic pulmonary fibrosis using microarray-based transcriptome profiling and single-nucleus RNA sequenc...
Published 2025-06-01“…Investigating the PCD patterns offers a novel approach to the early diagnosis and prognostic evaluation of IPF.MethodsThe study utilized microarray-based transcriptome profiling and single-nucleus RNA sequencing to identify and analyze diverse PCD patterns in IPF. …”
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