Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Two gastrointestinal events occurred, including one Grade 3 diarrhea treated with GCs. The overall GC usage rate was 31.7% (13/41), with 76.9% administered for Grade ≥3 irAEs. …”
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Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Disease burden was high and decreasing in low SDI regions, but low and stable in high SDI regions. The Age-standardized rate(ASR)-Deaths correlated negatively with SDI. …”
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Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
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Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
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Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Results Bacterial pathogens were isolated from 33 patients, representing an isolation rate of 22.1% (95% CI: 16.2–29.6%). Gram-negative bacteria (GNB) accounted for the majority of the isolates, 25/33 (75.8%), with Escherichia coli, 6/25 (24%) being the predominant species. …”
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Predicting sleep quality among college students during COVID-19 lockdown using a LASSO-based neural network model by Lufeng Chen, Qingquan Chen, Zhimin Huang, Ling Yao, Jiajing Zhuang, Haibin Lu, Yifu Zeng, Jimin Fan, Ailing Song, Yixiang Zhang

“…Results A mean PSQI total score of 6.03 ± 3.21 and a sleep disorder rate of 29.4% (PSQI > 7) were obtained. Sleep quality, sleep latency, sleep efficiency, diurnal dysfunction, and PSQI score were all higher than the national norm (P < 0.05). …”
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Rapid detection and quantification of Nile Red-stained microplastic particles in sediment samples by Masashi Tsuchiya, Tomo Kitahashi, Yosuke Taira, Hitoshi Saito, Kazumasa Oguri, Ryota Nakajima, Dhugal J. Lindsay, Katsunori Fujikura

“…In this study, we demonstrated the utility of the developed system by comparing its recovery rate and analysis time with those of the conventional methods used for manual processing. …”
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Behaviour of post released translocated greater one-horned rhinoceros (Rhinoceros unicornis) at Manas National Park, Assam, India by Deba Dutta, Amit Sharma, Rita Mahanta, Anindya Swargowari

“…Maximum grazing activity was observed in the monsoon (June–September) and retreating monsoon (October–November) seasons while it was observed that the grazing rate decreased during the dry winter season (December–February). …”
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Investigation of corrosion void formation in a Ni-based alloy under simulated MSW incineration condition by Xinxin Wu, Terrence Wenga, Wenchao Ma

“…Therefore, in this study, corrosion void formation and migration mechanism on a newly designed alloy (Ni–28Cr–13Al–5W-0.06B-0.005C) was investigated and the corrosion rate of the alloy was compared with that of Ni–20Cr alloy under simulated municipal solid waste (MSW) incineration conditions at 600 °C. …”
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Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection by Qingze Gu, Kevin Yuan, Jia Wei, Chang Ho Yoon, Anders Skyrud Danielsen, Augustine Luk, David W. Eyre, A. Sarah Walker

“…CRP percentile changes were modestly associated with subsequent antibiotic adjustments; in particular, suboptimal recovery, indicated by an increase in CRP centiles, was associated with a higher rate of antibiotic escalation (16.5% vs. 10.7% in expected recovery) and, conversely, faster than expected recovery in CRP was associated with de-escalation (23.6% vs. 17.2%). …”
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Assessing the Impact of Land Use Changes on Ecosystem Service Values in Coal Mining Regions Using Google Earth Engine Classification by Shi Chen, Jiwei Qin, Shuning Dong, Yixi Liu, Pingping Sun, Dongze Yao, Xiaoyan Song, Congcong Li

“…Land use change dynamics were quantified via a transfer matrix, while changes in the ESV were evaluated using the ecosystem sensitivity index and ecological contribution rate. Our results revealed notable fluctuations: forestland increased from 2013 to 2018 before declining sharply from 2019 to 2021; grassland displayed similar variability; and constructed land experienced a continual expansion. …”
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Tracking Pelagia noctiluca scyphomedusae by combining modeling and stable isotope approaches by Isabella D’Ambra, Isabella D’Ambra, Simona Saviano, Maria Assunta Ambrosio, Vincenzo Botte, Daniele Iudicone, Maria Grazia Mazzocchi, Louise Merquiol, Louise Merquiol, Louise Merquiol, Daniela Cianelli

“…SIs were determined in scyphomedusae and their potential planktonic prey collected at the Long Term Research site MareChiara (LTER-MC) during the outbreaks and during the previous three weeks, to account for the turnover rate of medusae. Numerical simulations were performed using a particle tracking model forced by a Regional Ocean Modeling System (ROMS) developed for the GoN. …”
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Gender differences in eating habits and sports preferences across age groups: a cross-sectional study by Stefania Gorini, Elisabetta Camajani, Edda Cava, Alessandra Feraco, Andrea Armani, Isaac Amoah, Tiziana Filardi, Xinyan Wu, Rocky Strollo, Massimiliano Caprio, Elvira Padua, Mauro Lombardo

“…Results Significant differences in body composition were observed between genders: men had a higher lean mass and basal metabolic rate, whereas women showed a higher fat mass in all age groups. …”
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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod... by Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S. Lee

“…The in vivo results revealed that the day-5 mortality rate and creatinine levels at days 2 and 5 were significantly greater in group 2 than in groups 1 and 5 ( P = 0.01), whereas the kidney injury score and inflammatory cell infiltration in the kidney were highest in group 2, lowest in group 1, and significantly greater in groups 3 and 4 than in group 5; however, there was no difference between groups 3 and 4 (all P < 0.0001). …”
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Intelligent prediction of thyroid cancer in China based on GBD data and hospital electronic medical records: disease burden analysis combined with multiple machine learning models by Lina Yang, Shixia Zhang, Xinguo Wang, Jianjun Yang, Mengya Chen

“…It comprehensively reveals the disease burden trend of thyroid cancer in China, predicts the mortality rate of thyroid cancer in China, and emphasizes the causal role of high BMI as an important controllable risk factor. …”
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Early maladaptive schemas in trichotillomania and skin-picking disorder: their relationships with symptom severity and subtypes by Ella Flagstad, Benjamin Hummelen, Erna Moen, Toril Dammen, Åshild Haaland, Tor Sunde, Bjarne Hansen, Diana Strand Johnsen, Douglas Woods, Torun Grøtte

“…Several EMSs were significantly positively associated with self-reported and clinician-rated symptoms and picking/pulling styles of TTM and SPD, with some indications of diagnosis-specific association patterns. …”
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Unmasking insider threats using a robust hybrid optimized generative pretrained neural network approach by P. Lavanya, H. Anila Glory, Manuj Aggarwal, V. S. Shankar Sriram

“…The structure of the proposed approach involves three phases: (1) Chebyshev Graph Laplacian Eigenmaps solver (CGLE) for selecting the user-designated samples by reducing the dimensionality of the data and Insider State clustering via Density-Based Spatial Clustering of Applications with Noise (IS-DBSCAN) (2) The EHI of multi-objective Bayesian optimization for optimizing the sensitive learning rate hyperparameter to ensure the stability of the Adabelief optimized WGAN and improve the quality of the generated adversarial samples. (3) The L2-SP regularization technique effectively fine-tunes the pretrained AGCN, which identifies the user behavioural pattern to detect the insiders. …”
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A STUDY TO ASSESS THE DISTRIBUTION OF SUSPECTED ADVERSE EVENTS FOLLOWING IMMUNISATION REPORTED IN A METROPOLITAN CITY IN INDIA by Sophie Simon, Shalini Rawat, Rohan Sangam, G D Velhal

“…Results: The AEFI reporting rate was calculated as 5.8 per 100000 doses administered per year. …”
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MODERN MOVEMENTS OF THE CRUST SURFACE IN GORNY ALTAI FROM GPS DATA by V. Yu. Timofeev, D. G. Ardyukov, A. V. Timofeev, E. V. Boiko

“…Analyzed are modern movements in the Gorny Altai region outside the Chuya earthquake area.The results of our study show that modern horizontal displacements occur in the NNW direction at the rate of 1.1 mm/yr, which is twice lower than the displacement rate before the earthquake.…”
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