Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis. by Fei Zhu, Pu Wang, Norman H Lee, Mary B Goldring, Konstantinos Konstantopoulos

“…Confirmation of the expression patterns of select genes was obtained by qRT-PCR. Using significance analysis of microarrays with a 5% false discovery rate, 71 and 60 non-redundant transcripts were identified to be ≥2-fold up-regulated and ≤0.6-fold down-regulated, respectively, in sheared chondrocytes. …”
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Optical Coherent Tomography-Angiography in the Research of Myopia Complicated by Choroidal Neovascularization by E. A. Drozdova, O. V. Zhiliaeva

“…Significant differences in the flat phenotype were revealed: neuroepithelial detachment (87.50 %) was more common, the Select Area and Flow Area of the neovascular complex was significantly greater both before treatment and at the end of the observation period, the mCNV course of continued growth after injection of anti-VEGF did not occur, recurrence rate is much higher. The area and perimeter of the foveal avascular zone (FAZ) in the eyes with mCNV increased significantly by the end of the observation. …”
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Trajectory, drivers, and reduction of greenhouse gas emissions from urban water system in China during 1980–2030 by Shiyu Pei, Zonghan Li, Yi Liu, Chunyan Wang, Hao Wu, Shuming Liu, Yujun Huang

“…Results show that over the 40 years, GHG emissions from China’s UWS increased approximately 14-fold, surpassing the overall rate of population growth by 143.9%. From the early 1990s till now, residential water use emerged as the dominant source of UWS-related emissions, accounting for approximately 77.6% of total emissions. …”
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ASSESSMENT OF ERYTHROCYTE PERIPHERAL BLOOD AND ACTIVITY OF HEMOST ASIS IN PATIENTS WITH CER VICAL CANCER by N. I. Stuklov, T. V. Sushinskaya

“…A statistically significant decrease in the concentration of hemoglobin and increased erythrocyte sedimentation rate is determined in the second stage of the disease. …”
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Spatiotemporal distribution and detection of spatial clusters of tuberculosis in Hubei Province, China using FleXScan (2017–2023) by Lina Wang, Yaru Li, Ji Chen, Danfei Zhang, Zhengbin Zhang, Xiang Li

“…Results Between 2017 and 2023, the incidence rate of Hubei Province decreased from 68.28 to 54.54 per 100,000 population. …”
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Verification of optimal position of shelf graft for acetabular dysplasia using finite element analysis and virtual surgery model by Yohei Yukizawa, Emi Kamono, Shu Takagawa, Shota Higashihira, Hyonmin Choe, Yutaka Inaba, Naomi Kobayashi

“…Moreover, the equivalent stress values on the acetabulum were significantly lower for lateral shelf placement than the anterior position (p < 0.05). The reduction rate of acetabular stress exhibited a significant correlation with the equivalent stress on the “inner shelf”, the part implanted in the pelvis, (p < 0.0001). …”
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Text Mining and Unsupervised Deep Learning for Intrusion Detection in Smart-Grid Communication Networks by Joseph Azar, Mohammed Al Saleh, Raphaël Couturier, Hassan Noura

“…The results demonstrate that the proposed approach can learn potential features from high-dimensional time series data while maintaining a high True Positive Rate.…”
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Epidemiology and Genetic Characterization of Distinct Ebola Sudan Outbreaks in Uganda by Francesco Branda, Massimo Ciccozzi, Fabio Scarpa

“…The 2022 outbreak involved 164 confirmed cases and a case fatality rate (CFR) of 33.5%, with significant geographic variation in case distribution. …”
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Low-frequency ultrasonic pulse-echo datasets for geometry determination of a reinforced concrete step specimen with embedded polystyrene foam cuboids in non-destructive testingData... by Maria Grohmann, Stefan Maack, Matthias Behrens, Ernst Niederleithinger

“…The ultrasonic raw data are stored in a universally readable format, with each time signal (A-scan) spanning two milliseconds and a sampling rate of two mega-samples per second. The provided data support comparative studies in signal analysis, imaging as well as interpretation and can be used for evaluation purposes in various practical NDT scenarios.…”
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The importance of Kinesio Taping Therapy on the Complex Gait Recovery of Patients with Drop Foot after Stroke by Alexandra Ionela PRALA, Luminita Ionela GEORGESCU, Ion MIHAILA, Elena Ioana ICONARU, Stefan TOMA

“…Compared to the control group, the experimental group showed a progress rate of 18.2% higher. Results support the hypothesis that the use of kinesio taping helps to optimize gait recovery in people with drop foot after stroke. …”
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Examining the Impact of Certificate of Need Laws on the Utilization and Reimbursement of Cataract Surgeries Among Medicare Beneficiaries by Alvina Liang, Jennifer L. Lindsey

“…Utilization and reimbursement patterns were analyzed in states with and without CON laws using the compound annual growth rate, with reimbursement adjusted by the US Bureau of Labor Statistics Consumer Price Index…”
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Fear-Pleasure Paradox in Recreational Fear: Neural Correlates and Therapeutic Potential in Depression by Zhan Y, Ding X

“…Although paradoxical enjoyment of fear has been documented in healthy populations, its neural and psychological mechanisms, and potential therapeutic value for depression, remain unclear.Methods: In a mixed‐methods design, Study 1 (N = 216) assessed psychological and physiological responses to standardized fear stimuli across a continuum of depressive symptoms, using heart rate variability, salivary cortisol, and validated self‐report measures. …”
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Does intraspecific variation in juvenile Late Cretaceous ammonoids correlate with their systematic position, longevity and paleogeography? by Amane Tajika, Takahiro Iida, Ryoji Wani, Neil H. Landman, Kenji Ikuno, Christian Klug

“…Additionally, scaphitid species from both Japan and North America display similar ontogenetic patterns of intraspecific variation. Hypophylloceras ramosum exhibits a pattern of intraspecific variation, differing from other normally coiled ammonoids. …”
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Gastric cancer radiation therapy: a bibliometric analysis of the scientific literature by Zhen-Hong Weng, Bin-Bin Chen, Jia-Rui Lin, Mu-Ming Xu, Jin-Peng Yuan, Hao-Kai Hu

“…Main thematic areas included isolated (niche) topics, emerging topics, hot (motor) topics, and necessary (basic) topics.ResultsA total of 2405 documents were initially retrieved, from which 484 articles closely related to gastric cancer radiation therapy were selected, showing an annual growth rate of -2.05%. Overall, publications were found in 186 different journals, with “FRONTIERS IN ONCOLOGY” being the most relevant journal. …”
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Evaluating Antibiotic Treatment Guideline Adherence to Ongoing Antibiotic Stewardship in a Tertiary Care Setting: A Retrospective Observational Study by Suman Pant, Andrew Corwin, Prabhat Adhikari, Subhash Prasad Acharya, Upasana Acharya, Sashi Silwal, Pratima Dawadi, Anil Poudyal, Vibhu Paudyal, Adisak Bhumiratana

“…This study revealed a low adherence rate despite the availability of updated guidelines for antibiotic prescriptions. …”
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Emotion-Aware Ensemble Learning (EAEL): Revolutionizing Mental Health Diagnosis of Corporate Professionals via Intelligent Integration of Multi-Modal Data Sources and Ensemble Tech... by Gaurav Yadav, Mohammad Ubaidullah Bokhari, Saleh I. Alzahrani, Shadab Alam, Mohammed Shuaib

“…Future iterations could enhance the framework by incorporating physiological signals, such as heart rate variability and EEG data, further improving diagnostic accuracy. …”
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Knowledge Structure and Emerging Trends of Mild Cognitive Impairment with Dyssomnias in Recent 20 Years: A Bibliometric Analysis via CiteSpace and VOSviewer by Haoyu Huang, Zesen Zhuang, Yiwen Wan, Jiao Shi, Xu Yuan, Dan Wang, Shangjie Chen

“…The publication volume and citation rate consistently increased over time. Neurosciences, Clinical Neurology, and Geriatrics Gerontology emerged as the top three research fields. …”
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Real-Time Fire Risk Classification Using Sensor Data and Digital-Twin-Enabled Deep Learning by In-Seop Na, Vani Rajasekar, Velliangiri Sarveshwaran

“…Performance evaluations reveal that the DCNN+Digital twin framework achieves a 99% classification accuracy with a reduced error rate of 3% over 500 runs, outperforming standalone models, such as RNN (90% accuracy, 10% error), CNN (96% accuracy, 8% error), and DCNN (97% accuracy, 6% error). …”
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Beyond genetics × environment interaction on quality drivers of Arabica coffee: a review of implication for Gedeo indigenous agroforestry systems under changing climates by Tedla Getahun, Girma Mamo, Getahun Haile, Daniel Markos, Gebremedhin Tesfaye

“…It was also found that native agroforestry systems were necessary for high-quality coffee due to well-established relationships between shade trees, coffee plants, and farmer management as these practices alter the microclimate including the soil carbon, moisture, and nutrition regimes, allowing it to adapt to changes in evapotranspiration patterns. More significantly, coffee quality is determined by the socioeconomic factors affecting livelihoods, such as the adoption of new technologies, credit availability, farm size, additional inputs, market knowledge, physical infrastructure, extension services, literacy rate, frequency of extension visits, proximity to research centers, and producer incentives. …”
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Comprehensive analysis of kampo medicine utilization across all outpatient departments with a focus on anesthesiology department/pain clinic at Kyoto university hospital over 12 ye... by Karin Kato, Kaori Tsuyuki, Takuma Ohsuga, Akihiko Ueda, Miho Egawa, Masashi Ikuno, Neiko Ozasa, Kiyoaki Tanikawa

“…The anesthesiology department prescribed various formulations for 12 years. The usage rate of Processed Aconite Root-containing formulations increased with increasing patient age, reaching 3.3% in individuals in their teens, 6.6% in their twenties, 13.3% in their thirties, and over 30% in their eighties and nineties. …”
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