The efficacy and safety of remimazolam for the management of emergence agitation: a randomized, double-blind, placebo-controlled study by Xiaoxing Lu, Xiaoxing Lu, Meiyan Zhou, Yao Lu, Yao Lu, Jia Sun, Kexin Mao, Yangzi Zhu, Yangzi Zhu, Rongguo Wang, Yong Cao, Liwei Wang, Liwei Wang, Liwei Wang

“…Secondary outcomes included rescue propofol dosage, EA duration, and the post-anesthesia care unit (PACU) discharge time. …”
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Longitudinal NMR-based Metabolomics Analysis of Male Mountain Ultramarathon Runners: New Perspectives for Athletes Monitoring and Injury Prevention by Matthieu Schoumacher, Julie Nguyen, Eric Brevers, Arianna Cirillo, Manon Campas, Elodie Grifnée, Justine Demeuse, Loreen Huyghebaert, Philippe Massonnet, Thomas Dubrowski, Joy Ledeck, Stéphanie Peeters, Grégoire P. Millet, Pierre Croisille, Jean-François Kaux, Pascal de Tullio, Etienne Cavalier, Caroline Le Goff

“…Sixteen healthy male athletes (43.9 ± 10.1 years) were recruited, and blood samples were collected at four time points: pre-race, mid-race, post-race and after 72 h recovery. Using a 1H-NMR-based metabolomic approach, we evaluated metabolic changes that occur during both race effort and recovery, and correlated them with functional muscle, cardiac, inflammatory, and renal biomarkers already used in the clinic. …”
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Aerial legacies of COVID-19 by F. Klauser

“…Aiming to perpetuate the lessons learnt from the respiratory disease, the quoted white paper asks for the development and implementation of a wide range of novel and/or improved air-related technological solutions whilst also suggesting, on a more general level, the establishment in Switzerland of a National Research Programme on “Clean air for pandemic-proof buildings” and the creation of an “Indoor air competence center” (Expert group “Pandemic-proof buildings”, 2022:4). The emerging post-pandemic policy agenda resonates with many other media-reported claims for long-term improvements of the indoor air quality in schools (Direction de la formation et des affaires culturelles, 2022; Eykelbosh, 2022), factories (Wirth, 2021), hospitals (Bourban, 2022) or trains (Monay, 2022). …”
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Paradigms of the agricultural system in times of COVID-19 by Luis Edgar Blanco-Capia

“…However, it faces various environmental threats and in recent years, biological threats, which have caused economic damage to agricultural production, specifically during the 2019-2020 agricultural cycle, agro-productive systems were indirectly affected by conflicts post-election social (November - December 2019) and the Covid-198 health crisis, which increased poverty and aggravated inequalities1, since it affected the provision of agricultural inputs, the collection, marketing, distribution, and consumption, due to the fact that the main crops such as potatoes, corn, barley, quinoa, corn among others were in the middle of the harvest process, the commercialization of fruits such as prickly pear, peach, grape, avocado, among others, were in full commercialization8. …”
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Anti-Tyrosinase and Radical Scavenging Activities of Selected Cassipourea Plants and Isolated 7-Methoxygeranin A: Traditional Use as Skin Lighteners by Mpofana N, Paulse M, Yalo M, Dlova NC, Hussein A, Lanrewaju AA, Lukman HY, Aribisala JO, Rautenbach F, Marnewick JL, Sabiu S

“…Statistical analyses, including ANOVA and post-hoc tests, compared extract activities.Results: C. flanaganii exhibited the most potent anti-tyrosinase activity (IC50: 37.10 μg/mL), though statistical differences among species were non-significant. …”
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Safety of pericardiocentesis in pulmonary arterial hypertension: a systematic review by Maria Jose Cabada-Garcia, Maria Jose Cabada-Garcia, Jahir Rodriguez-Rivera, Carlos Jerjes-Sanchez, Carlos Jerjes-Sanchez, Mauricio Castillo-Perez, Paola Gutierrez-Gallegos, Ana Lucia Martinez-Rodriguez, Enrique Paredes-Gutierrez, Renata Claudia Quevedo-Salazar, Humberto De Leon-Gutierrez, Oscar David Lopez-Cortes, Jathniel Panneflek, Jathniel Panneflek, Raul Monjaras-Alvarado, Jesus Antonio Moron-Mosso, Jaime Guillermo Gonzalez-Medina

“…IntroductionControversy persists regarding the use of pericardial effusion drainage in patients with pulmonary arterial hypertension (PAH), as several studies report high rates of post-procedure morbidity and mortality.MethodsWe conducted a systematic review to evaluate the safety of pericardiocentesis (PC) in patients with PAH and a large or hemodynamically significant pericardial effusion. …”
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Electronic Structures of Molecular Beam Epitaxially Grown SnSe₂ Thin Films on <inline-formula><math display="inline"><semantics><mrow><msqrt><mn mathvariant="bold">3</mn... by Zhujuan Li, Qichao Tian, Kaili Wang, Yuyang Mu, Zhenjie Fan, Xiaodong Qiu, Qinghao Meng, Can Wang, Yi Zhang

“…SnSe₂, as a prominent member of the post-transition metal dichalcogenides, exhibits many intriguing physical phenomena and excellent thermoelectric properties, calling for both fundamental study and potential application in two-dimensional (2D) devices. …”
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Brachial Plexopathy in Head and Neck Cancer Potentially Related to LET-Dependent RBE by Abanob Hanna, Anthony Casper, Roi Dagan, Hardev S. Grewal, Jiyeon Park, Eric D. Brooks, Erik Traneus, Lars Glimelius, Perry B. Johnson, Mohammad Saki, Yawei Zhang, Twyla R. Willoughby, Julie A. Bradley, Jackson Browne, Mark E. Artz

“…Due to a right level 4 neck node, the high-risk target volume overlapped with the brachial plexus, resulting in a D0.1cc of 70.3 Gy (RBE = 1.1). Four years post-treatment, the patient developed progressive right upper extremity paresthesia, weakness, and dysesthesia. …”
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Green synthesis of silver nanoparticles using Pyrostegia venusta extract, characterization and estimation of antioxidant, antiglycation and anti-aging activities by Regildo Márcio Gonçalves da Silva, Pedro Augusto Pereira Rosatto, Isabelly do Nascimento Pereira, Laura Camargo Zibordi, Hugo Henrique Santos, Filipe Oliveira Granero, Célia Cristina Malaguti Figueiredo, Patrícia Soares Santiago, Carlos Augusto Prata Gaona, Nilson Nicolau-Junior, Luciana Pereira Silva

“…PvAE presented in vitro enzymes inhibition and in silico studies demonstrated possible active binding sites between P. venusta main compounds and enzymes that may be correlated with their potential to act at pre- and post-transcriptional levels. Therefore, this study provides information regarding P. venusta and demonstrates that further studies are needed to evaluate its application.…”
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Experiences and outcomes of older adults with obesity transitioning from gym- to home-based resistance training due to COVID-19 lockdowns: a mixed-methods analysis of a RCT by Costas Glavas, Jakub Mesinovic, Anoohya Gandham, Mavil May Cervo, Carrie-Anne Ng, Peter R. Ebeling, Elena S. George, Robin M. Daly, Belinda R. Beck, Paul Jansons, David Scott

“…Eight HOME participants completed semi-structured interviews post-intervention. Quantitative outcomes including exercise adherence, body composition and physical function were compared to GYM participants. …”
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Anew yellow-flesh nectarine cultivar Zhongnong Zhenzhu 4 by WANG Yingying, LIU Lichang, LIU Zhiwu, YANG Xingwang, WANG Xiaodi

“…Fruit matures in mid-August, approximately 130 days post-bloom, and a harvesting period extends over 5 days. …”
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Longitudinal dynamics of the nasopharyngeal microbiome in response to SARS-CoV-2 Omicron variant and HIV infection in Kenyan women and their children by Ayla Žuštra, Victoria R. Leonard, LaRinda A. Holland, James C. Hu, Tianchen Mu, Steven C. Holland, Lily I. Wu, Emily R. Begnel, Ednah Ojee, Bhavna H. Chohan, Barbra A. Richardson, John Kinuthia, Dalton Wamalwa, Jennifer Slyker, Dara A. Lehman, Soren Gantt, Efrem S. Lim

“…Since individuals were sampled longitudinally before and after SARS-CoV-2 infection, we could characterize the short- (within a week of infection) and longer- (average of 38 days post-infection) term impact of SARS-CoV-2 infection on the nasopharyngeal microbiome. …”
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Synthesis and Evaluation of [¹⁸F]AlF-NOTA-iPD-L1 as a Potential Theranostic Pair for [¹⁷⁷Lu]Lu-DOTA-iPD-L1 by Guillermina Ferro-Flores, Myrna Luna-Gutiérrez, Blanca Ocampo-García, Nallely Jiménez-Mancilla, Nancy Lara-Almazán, Rigoberto Oros-Pantoja, Clara Santos-Cuevas, Erika Azorín-Vega, Laura Meléndez-Alafort

“…Biodistribution studies indicated a tumor uptake of 6.4% ± 0.9% ID/g at 1-hour post-administration, and Cerenkov images showed a high tumor uptake of both [¹⁸F]AlF-NOTA-iPD-L1 and ¹⁷⁷Lu-iPD-L1 in the same mouse. …”
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PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report

“…He remained asymptomatic, except for a slight bruising tendency (he plays soccer), and continued a weekly prophylaxis with PCC 30-40 U/kg. From 2020, due to post-infusion unspecific symptoms (nausea, sometimes dizziness) he performs premedication with Betametasone 1 mg, infusing PCC 25-30 U/kg weekly and FX trough between 1-1.8 U/dL. …”
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Evaluation of a patient decision aid for opportunistic salpingectomy and salpingectomy as sterilization method to prevent ovarian cancer by Malou E. Gelderblom, Charlotte Fisch, Jurgen M. J. Piek, Laura A. M. vanLieshout, Justine Briet, Lauren Bullens, Sjors F. P. J. Coppus, Inge Ebisch, Alexandra A. vanGinkel, Rafli van deLaar, Natascha deLange, Marloes Maassen, Huy Ngo, Angele L. M. Oei, Brenda Pijlman, Brigitte Slangen, Regina The, Dineke Smedts, Caroline Vos, Joanna IntHout, Joanne A. deHullu, Rosella P. M. G. Hermens

“…Digital questionnaires were used to evaluate the decision aid, the decision process, and patients' decisions 6–8 weeks post‐surgery. Results 425 out of 542 patients participated in the questionnaire. …”
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Radiofrequency Ablation of Painful Spinal Metastasis: A Systematic Review by Jacopo Scaggiante, Salvatore Marsico, Andrea Alexandre, Simona Gaudino, Monica Ferrante, Riccardo Caronna, Ettore Squillaci, Iacopo Valente, Giuseppe Garignano, Francesco D’Argento, Reade De Leacy, Alessandro Pedicelli

“…Inclusion criteria specified: randomized or non-randomized studies (prospective/retrospective); ≥3 adult patients; RFA used alone or combined with other treatments; reported pre- and post-RFA pain assessments; English language publication. …”
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Reduction of the risk of bronchopleural complications after pneumonectomy due to the use of intraoperative laser treatment of the stump of the main bronchus by G. A. Asoyan, L. N. Lepekha, S. S. Sadovnikova, R. V. Tarasov, V. K. Aliev, M. A. Bagirov

“…These patients, as part of preoperative preparation, underwent endoscopic biopsy of the main bronchus mucosa in the scar areas, and only after histological confirmation of the absence of active tuberculous inflammation, pneumonectomy was performed.Results. Pronounced post-thoracotomy pain syndrome in 5.2% (n = 3) of patients in the main group and in 9.3% (n = 5) of patients in the control group, for the relief of which narcotic analgesics were used for a long time. …”
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Theater testing a sexual and reproductive health program for Latina teens and their female caregivers: a mixed methods study by Katherine G. Merrill, Jacqueline Silva, Jaime Atadero, Ivy Lee Hung, Susana Salgado, Jennifer K. Cano, Veronica Nabor, Angela Sedeño, Sara Vargas, Gisel Romero, Carol Perez, Jamison Merrill, Jeff DeCelles, Jacqueline Fuentes, Kate Florence, Laura Rodriguez, Corin Mora, Ana A. Baumann, Kate Guastaferro, Geri R. Donenberg

“…Observers (n = 8) and facilitators (n = 2) completed surveys, recorded activity start and end times, and participated in a post-program discussion. Survey item ratings were on four-point Likert scales, with higher scores indicating more favorable results. …”
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Short-term outcomes of transcatheter perimembranous ventricular septal defect closure using the konar-multifunctional occluder: the Taiwanese experience by Li-Chin Liao, Li-Chin Liao, Li-Chin Liao, Li-Chin Liao, Li-Chin Liao, Yun-Ching Fu, Yun-Ching Fu, Yun-Ching Fu, Pi-Chang Lee, Sheng-Ling Jan, Ming-Chih Lin, Ming-Chih Lin, Chieh-Mao Chuang, Hui-Chih Hung, Hui-Chih Hung, Hui-Chih Hung, Hui-Chih Hung

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Long-Term Outcome After Mustard Repair at Young Age by Sahra Ünlütürk, MD, Robert M. Kauling, MD, Judith A.A.E. Cuypers, MD, PhD, Annemien E. van den Bosch, MD, PhD, Alexander Hirsch, MD, PhD, Mieke M.P. Driessen, MD, PhD, Chiara Pelosi, MD, PhD, Daniel J. Bowen, PhD, Ad J.J.C. Bogers, MD, PhD, Willem A. Helbing, MD, PhD, Isabella Kardys, MD PhD, Jolien W. Roos-Hesselink, MD, PhD

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