Deep Learning Models for Detection and Severity Assessment of Cercospora Leaf Spot (<i>Cercospora capsici</i>) in Chili Peppers Under Natural Conditions by Douglas Vieira Leite, Alisson Vasconcelos de Brito, Gregorio Guirada Faccioli, Gustavo Haddad Souza Vieira

Get full text

Integration of phospho-signaling and transcriptomics in single cells reveals distinct Th17 cell fates by Seth D. Fortmann, Awalpreet S. Chadha, Blake F. Frey, Asif Elahi, Vidya Sagar Hanumanthu, Shanrun Liu, Andrew Goldsborough, P. Brent Ferrell, Jr., Maria B. Grant, Casey T. Weaver, Robert S. Welner

“…Summary: Single-cell RNA sequencing (scRNA-seq) provides the resolution and scale necessary to identify transcriptional programs but fails to capture post-transcriptional information critical to decipher signaling networks and cellular states. …”
Get full text

Evaluation of the CRISPR/Cas9 system as genome editing platform for the Mucopolysaccharidosis IV A using a strategy for induction of higher homologous recombination frequency by Diego Alejandro Suarez, Andrés Felipe Leal, Carlos Javier Alméciga Díaz

“…The CRISPR/Cas9 vectors were transfected in GM00593 and GM01361 human MPS IVA fibroblasts using a lipofection-based delivery. After 30 days post-transfection with CRISPR/Cas9 systems in the absence of the E4orf6 or E1B, we found an increase in the GALNS activity up to 4.17 and 11.2-fold when compared to untreated GM01361 and GM00593 cells, respectively. …”
Get full text

An Optimized Method for Single Cell Cloning of Human CAR-T Cells Based on FBS-Coated Plates by Mahdie Jafari, Shahriyar Abdoli, Masoud Moghaddam Pour, Mohammad Ali Shokrgozar, Zahra Sharifzadeh

“…Among the Jurkat cells, 57.1% showed GFP expression post-transduction, of which 34.1% showed surface expression of anti-PSMA CAR. …”
Get full text

Pulse Dynamics in Reduced Graphene Oxide Electrolyte‐Gated Transistors: Charge Memory Effects and Mechanisms Governing the Ion‐To‐Electron Transduction by Guilherme Segolin Selmi, Eduardo Rodrigues Lourenço Neto, Gabrielle Coelho Lelis, Anderson Kenji Okazaki, Antonio Riul Jr., Maria Luisa Braunger, Rafael Furlan de Oliveira

“…Multiple low‐level (0.1 V) fast pulsing (100 ms) further demonstrate charge retention post‐stimulation. All these characteristics are attributed to a complex interplay between ion entrapment within the rGO film, electrical double‐layer formation, and charge transfer processes. …”
Get full text

Cardiac Electrophysiological Effects of the Sodium Channel-Blocking Antiepileptic Drugs Lamotrigine and Lacosamide by Julian Wolfes, Philipp Achenbach, Felix K. Wegner, Benjamin Rath, Lars Eckardt, Gerrit Frommeyer, Christian Ellermann

“…The action potential duration at 90% repolarization (APD₉₀), QT intervals, spatial dispersion of repolarization, effective refractory period, post-repolarization refractoriness, and VT incidence were determined. …”
Get full text

Hyaluronic Acid Combined with Diluted and Hyperdiluted Calcium Hydroxylapatite to Treat the Periocular Area by Spada J, Van Loghem J

“…One patient underwent a comparative analysis of HA alone versus the HA-CaHA blend, evaluated through ultrasound, Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scan post-injection.Results: All treated patients presented natural-looking results, less pronounced PG and SH with minimal edema on D30, and skin quality improvement with less laxity, wrinkling and pigmentation. …”
Get full text

Behavior change interventions for dangerous driving behavior in low- and middle-income countries: a systematic review of interventions and outcome measurement instruments by Saen Fanai, Eunice Okyere, Kissinger Marfoh

“…ObjectiveThis systematic review aims to assess Behavior Change Interventions (BCIs) targeting dangerous driving behaviors (DDBs) in low- and middle-income countries (LMICs), evaluate their effectiveness, and explore the outcome measurement instruments employed in these contexts.MethodA comprehensive search was performed across key databases such as Scopus, PubMed, CINAHL, Medline, ProQuest, Cochrane Library, and Research4life, focusing on studies published post-2015 on BCIs for DDB using randomized controlled trials (RCTs), quasi-experiments and mixed method designs. …”
Get full text

The Effect of Volitional Preemptive Abdominal Contraction on Biomechanical Measures During A Front Versus Back Loaded Barbell Squat by Joseph B. McCormick, Alexander S. Drusch, Darragh J. Lynch, Gesine H. Seeber, Katherine F. Wilford, Troy L. Hooper, Brad S. Allen, Dennis G. O’Connell, Maria J. Mena-Iturriaga, Kinyata J. Cooper, Phillip S. Sizer

“…Significant interactions and main effects were tested using a 2(VPAC strategy) x 2(squat variation) and 2(VPAC strategy) x 2(direction) within-subject repeated measures ANOVAs. Tukey's Post-Hoc tests identified the location of significant differences…”
Get full text

Abstract 244: Effect of Actuation Frequency on Clot Integration with the Tigertriever Device: An In Vitro Study by Nakisa Dashti, Megha Gopal, Rowan J Serna, David Fiorella, Chander Sadasivan

“…Results The CIF was significantly higher (23% increase, p=0.01) with the Fast actuation as compared to the Passive and Slow actuations, with a post‐hoc test showing no difference (p>0.05) between the Passive and Slow actuation frequency (Figure 1B). …”
Get full text

Risk Factors and Prevalence of Suicide in Chilean University Students by Jonathan Martínez-Líbano, María-Mercedes Yeomans-Cabrera, Guillermo Barahona-Fuentes, Nicolás Santander Ramírez, Roberto Iturra Lara, Valentina Cortés Silva, Rumiko Okamoto

“…These findings highlight the urgent need for targeted mental health interventions and policy actions in Chilean higher education to address post-pandemic increases in suicide-related behaviors.…”
Get full text

Effects of Three Sessions of Diaphragmatic Myofascial Release on Pain, Balance, and Quality of Life in Patients with Chronic Nonspecific Low Back Pain (A Regional Interdependence M... by soheil hejazi yekta, kazem malmir, Sara Fereydounnia, Khadijeh Otadi, Fatemeh Ehteshami

“…Outcome measures will be assessed at baseline, after the third session (post-treatment), and after one week (follow-up). …”
Get full text

Prognostic value of cough force measured by peak expiratory flow in a 4-year longitudinal cohort study of geriatric patients with oropharyngeal dysphagia by Kiril Stoev, Rainer Wirth, Bendix Labeit, Paul Muhle, Sonja Suntrup-Krueger, Rainer Dziewas, Gero Lueg, Ulrike Sonja Trampisch, Maryam Pourhassan

“…Cox regression models, adjusted for potential confounding variables such as age and gender, were used to explore the relationship between pneumonia incidence, PF and dysphagia severity.ResultsAmong 98 patients (mean age 80.4 ± 8.2 years, 67% male), the median PEF was 220 L/min (IQR 150–300). Post-discharge, 38% developed pneumonia—11% had one episode and 27% had multiple episodes. …”
Get full text

Nationwide conflict damage mapping with interferometric synthetic aperture radar: A study of the 2022 Russia–Ukraine conflict by Corey Scher, Jamon Van Den Hoek

“…Given the proliferation of urban armed conflicts around the world, the results of this study show a promising path forward not only for nationwide, sustained damage mapping but also for informing post-conflict recovery and rebuilding with a transparent and replicable approach.…”
Get full text

Design of a Randomized Sham-Controlled Trial: Strengthening Positive Treatment Expectations Using a Communication Model for Maximized Antiemetic Effects of Acupuncture and Antiemet... by Widgren Ylva MSP, Fransson Per PhD, Englund Erling PhD, Efverman Anna PhD

“…The 2 communication styles 1 and 2 are carried out during the antiemetic treatments given by an intervention therapist immediately pre and post (20 minutes × 2) an intravenous chemotherapy session. …”
Get full text

An evaluation of the alignment of drought policy and planning guidelines with the contemporary disaster risk reduction agenda by I. Masih

“…Most elements under priority 4 (enhancing disaster preparedness) scored in the medium-low to medium-high ranges, as sufficient information was lacking on multi-hazard early-warning systems; post-disaster recovery, rehabilitation, and reconstruction; and the resilience of critical infrastructure. …”
Get full text

Neurophysiological Markers of Adaptation and Compensation Following Lower Limb Amputation: An Analysis of EEG Oscillations and Clinical Predictors from the DEFINE Cohort Study by Guilherme J. M. Lacerda, Valton Costa, Lucas Camargo, Linamara R. Battistella, Marta Imamura, Felipe Fregni

“…<b>Background:</b> Neuroplasticity, involving cortical and subcortical reorganization, plays a critical role in the adaptation and compensation process post-amputation. However, underlying neurophysiological changes remain unclear, particularly in brain oscillations. …”
Get full text

Mehran vs. Mehran2 pre-procedure: which score better predicts risk of contrast-induced acute kidney injury in patients with acute coronary syndrome? by Matheus Santos Moitinho, Dulce Barbosa, Attilio Galhardo, Adriano Caixeta, Eduesley Santana-Santos, Maximina Cunha, Beatriz Santana Prado, Cassiane Dezoti da Fonseca

Get full text

Comparative analysis of isokinetic muscle function, anaerobic power, and physical fitness in male Taekwondo players based on body mass index standards by Minhyuk Park, Yonghyun Byun, Sangho Kim

“…Measurements were analyzed using one-way Analysis of Variance (ANOVA) with Scheffe’s post-hoc test for group comparisons. Results: Isokinetic assessments revealed that OWG and OG demonstrated significantly higher right (F = 7.517, p < 0.01) and left (F = 9.664, p < 0.001) extensor strength compared to NWG. …”
Get full text

Anesthesia-induced developmental neurotoxicity in the setting of systemic inflammation: the role of microglia by Nemanja Useinovic, Adre Newson, Michelle Near, Stefan Maksimovic, Benjamin Volvovitz, Nidia Quillinan, Nidia Quillinan, Vesna Jevtovic-Todorovic

“…To improve our understanding of the underlying mechanisms, here we focused on multicellular interactions between damaged neurons and microglia since microglia is the resident macrophages within the brain that respond to stress. Using infant rats (post-natal day 7) and most commonly used inhaled anesthetic, sevoflurane, we examine microglia role in sevoflurane-induced inflammation-propagated developmental neurotoxicity. …”
Get full text