THE SOCIAL SECURITY SYSTEM OF INDIVIDUALS AS A KEY DETERMINANT IN IMPLEMENTING THE ECONOMIC POLICIES OF BUSINESS ENTITIES by Zakharii Varnalii, Oksana Mykytiuk, Tetiana Onysenko, Ihor Pampukha

“…However, a gap remains in Ukrainian business practices regarding the implementation of CSR models focused on internal social security—a gap that is particularly significant during crises such as wartime and post-war recovery. This article addresses this gap by providing a comprehensive analysis of CSR- based social security and its potential to enhance employee morale, loyalty, and productivity under adverse conditions. …”
Get full text

Prevalence and Economic Burden of Pulmonary Hypertension and Pulmonary Arterial Hypertension Among the Medicaid Population by Marshaleen Henriques King, Chaohua Li, Vincent C. Bond, Dimitri Ford, Peter Baltrus, Harrison W. Farber

“…We used one‐way analysis of variance (ANOVA) tests to compare the differences in hospital bed days and total Medicaid cost across racial subgroups among those with PH and those without PH; Tukey post hoc tests were performed to calculate p‐values for comparing White and Black subpopulations. …”
Get full text

Efficacy and safety of afoxolaner (NexGard®) in a collection of captive-bred lizards for the treatment and control of mite infestation by Jairo Alfonso Mendoza-Roldan, Livia Perles, Chiara Miuli, Pietro Larichiutta, Matteo Legrottaglie, Marcos Antônio Bezerra-Santos, Rossella Samarelli, Philippe Berny, Frederic Beugnet, Domenico Otranto

“…All animals were examined pre-treatment (T0) and at various time points post-treatment (T1, 24 h; T2, 14 days; T3, 28 days). …”
Get full text

Effectiveness of the BOPPPS-MDT Model in Enhancing ECMO Training for ICU Staff: A Randomized Controlled Trial Assessing Knowledge, Skills, and Teamwork Outcomes by Zhou W, Huang L, Tang W

“…This study aimed to evaluate the effectiveness of the BOPPPS-MDT (Bridge-in, Objectives, Pre-assessment, Participatory Learning, Post-assessment, and Summary model integrated with Multidisciplinary Team) teaching model in enhancing ECMO training for ICU staff.Methods: A total of 108 ICU interns with diverse educational backgrounds and majors were randomly assigned to two groups: 54 in the control group and 54 in the experimental group. …”
Get full text

Dayuan Yin alleviates symptoms of HCoV-229E-induced pneumonia and modulates the Ras/Raf1/MEK/ERK pathway by Rui Li, Wen Zhang, Bei Huang, Guotong Sun, Yifei Xie, Junke Song, Shumei Wang, Guanhua Du

“…The respiratory function and organ indices post-treatment were assessed. Lung tissue and tracheal lesions were evaluated via immunohistochemistry. …”
Get full text

Detection of a Mixed-Strain Infection with Drug- and Multidrug-Resistant <i>Mycobacterium avium</i> Subspecies <i>hominissuis</i> in a Dog with Generalized Lymphadenomegaly by Cinzia Marianelli, Angelo Leonori, Romana Stecco, Carlo Giannantoni

“…<b>Methods</b> Laboratory investigations, as well as the monitoring of the clinical signs displayed by the animal, were conducted throughout the course of a two-year drug therapy (based on rifampicin, azithromycin, and ciprofloxacin) and a two-year post-treatment follow-up period, until the death of the dog. …”
Get full text

PENGARUH EKSTRAK JAHE MERAH (Zingiber officinale var.Rubrum) TERHADAP KADAR AST DAN ALT DARAH TIKUS SETELAH PAPARAN ASAP ROKOK by Novritasari Setyaningrum, Budhi Surastri Soejoto

“…Tujuan : Mengetahui pengaruh ekstrak Jahe merah (Zingiber Oficinale Var Rubrum) terhadap kadar AST dan ALT darah tikus setelah paparan asap rokok Metode : Penelitian ini menggunakan metode true experimental dengan desain post test only control group design pada tikus jantan. …”
Get full text

Exploring the Benefits of 3D Smart MRI in Resident Training and Surgical Planning for Transcervical Radiofrequency Ablation by Sepehr Janghorbani, Victoria Weprinsky, Alexandre Caprio, Tamatha Fenster, Bobak Mosadegh

“…Additionally, participants completed post-procedure user experience questionnaires to assess the perceived utility and ease of use of the 3D tool. …”
Get full text

PM2.5 Exposure in the Respiratory System Induces Distinct Inflammatory Signaling in the Lung and the Liver of Mice by Soi Jeong, Sang A Park, Inwon Park, Pilhan Kim, Nam Hoon Cho, Jin Won Hyun, Young-Min Hyun

“…Interestingly, quantification of leukocyte population using flow cytometry showed significant increase of neutrophils and macrophages in the lung, but not much in the liver, 24 h post-PM2.5 treatment. These data imply that two-photon intravital imaging of the lung and the liver actually visualized neutrophils, which were adherent to the luminal side of the vasculature. …”
Get full text

Reusing of intraoperative exfoliated finger epidermis in the treatment of hand scar contracture in patients with RDEB by Chong Wu, Teng Guo, Yuluo Jian, Xinhe Jiao

“…This study pioneers the clinical application of intraoperatively shed epidermal tissue for fabricating autologous epidermal finger cuffs to cover post-surgical defects, evaluating its therapeutic efficacy. 13 RDEB patients with hand contractures were stratified into experimental (n = 6, autologous epidermal finger cuffs) and control (n = 7, traditional petrolatum gauze dressings) cohorts following standardized contracture release procedures. …”
Get full text

Pengaruh pemberian ekstrak daun belimbing wuluh (averrhoa bilimbi l.) Terhadap histopatologi dan fungsi ginjal Tikus model hiperurisemia by Wilbert Waldo Utomo, Chrismis Novalina Ginting, Linda Chiuman, Andika Zayani Tambunan, Widya Pasca Amir

“…Jenis penelitin ini merupakan penelitian eksperimen dengan menggunakan pre and post test control group design. Sampel penelitian ini menggunkan hewan uji tikus galur wistar dengan jumlah sampel sebanyak 25 ekor tikus yang dibagi kedalam 5 kelompok dengan kelompok 1 sebagai kontrol negatif tanpa perlakuan, kelompok 2 diberikan alopurinol, kelompok 3 diberikan ekstrak daun belimbing wuluh dengan dosis 100 mg, kelompok 4 diberikan ekstrak daun belimbing wuluh dengan dosis 500 mg dan kelompok 5 diberikan ekstrak daun belimbing wuluh dengan dosis 800 mg. …”
Get full text

Geographic Origin and Functional Group Type Affect the Decomposability of Peatland Plant Litter Through Biochemical Properties by Jinze Ma, Yong‐Da Chen, Si‐Nan Wang, Jing Zeng, Chao Liu, Zhao‐Jun Bu

“…Decomposition rates and key biochemical traits were quantified through sequential destructive sampling at 0‐, 1‐, 2‐, and 3‐year post‐deployment. Results showed decomposition rates of plant litter descending as Carex > Betula > Sphagnum. …”
Get full text

Management of Farm Development and Their Role in the Socio-Economic Recovery of Rural Areas by Oleksandr Shpykuliak, Mariana Humeniuk, Diana Shelenko, Dmytro Nemish, Sergiy Balaniuk

“…The functions of farms in the post-war reconstruction of rural areas are substantiated.According to the results of the assessment of the current state and development of farms in Ukraine, it was determined that the average area of one farm is 187 hectares, and the share of farms occupying an area of up to 100 hectares is 68.9% of the total number of farms. …”
Get full text

Preoperative loop length determination for mitral valve repair by 4-dimensional computed tomographyCentral MessagePerspective by Kazumasa Tsuda, MD, Naoki Washiyama, MD, Masahiro Hirano, MD, Yuko Ohashi, MD, Ken Yamanaka, MD, Yuki Takeuchi, MD, Kenji Kishita, MD, Norihiko Shiiya, MD

“…Measurements were made on the commissural and long-axis views created by a medical image post-processor in the late systolic phase. This technique was used in consecutive 45 patients undergoing mitral valve repair with the loop technique since April 2021. …”
Get full text

High-dose high-intensity Queen Square upper-limb rehabilitation for people with chronic stroke (INTENSIVE): protocol for a single-centre, randomised controlled trial by Fran Brander, Kate Kelly, Nick Ward, Sven Bestmann, Lisa Tedesco Triccas, Sebastian Sporn, Mireia Coll I Omana

“…Outcome measures will be collected at (T1) baseline; (T2) immediately post intervention and (T3) 3 months after the intervention has finished. …”
Get full text

The Effects of Intensive Blood Pressure Control on Cardiovascular Outcomes Based on 10-Year ASCVD Risk Score: An Analysis of a Clinical Trial by Alireza Alborzi, Armin Attar, Mehrab Sayadi, Fatemeh Nouri

“…There is still controversy about whether clinicians should include cardiovascular disease (CVD) risk stratification into the consideration for treatment of hypertension. This was a post hoc analysis of the Systolic Blood Pressure Intervention Trial (SPRINT). …”
Get full text

Valoración del estado nutricional antes y después del tratamiento de quimioterapia en fase de inducción en niños y adolescentes con leucemia. by Rosana Elizabeth Maidana, María Agustina Bianciotti, Gabriela del Valle Mori, Gabriela Natalia Ávila Sabattini, Nahuel Alejandro Ojeda, Ricardo Daniel Vera, Micaela Natalia Campero, Verónica Mamondi, Carlos Matias Scavuzzo

“…Se observó una menor concentración de hemoglobina (90%) y de albúmina (35,7%) post inducción. Conclusión: Se observaron cambios en el peso en casi la totalidad de los niños y adolescentes tendiendo principalmente a su aumento. …”
Get full text

Expression of a Novel HIV-1 Gag-Pol-Env-Nef-Rev Multi-Epitope Construct in Escherichia coli by Elahe Akbari, Soheila Ajdari, Esmat Mirabzadeh Ardakani, Elnaz Agi, Vahid Khalaj, Azam Bolhassani

“…The gag-pol-env-nef-rev gene was successfully sub-cloned in pET-24a (+) vector and subsequently expressed in BL21 (DE3) E. coli strain under optimized conditions (1 mM IPTG, 16 h post-induction, OD 600= 0.6, and 37ºC). A clear band of ~ 35 kDa was detected by western blotting using an anti-His antibody, indicating the successful expression of our target multi-epitope protein. …”
Get full text

Rearrangement of the liver ubiquitome and NEDDylome in metabolic dysfunction-associated steatotic liver disease by Teresa C. Delgado, Benoît Lectez, Marina Serrano-Maciá, Fernando Lopitz-Otsoa, Leire Uraga-Gracianteparaluceta, Ibon Martínez-Arranz, Jesús M. Arizmendi, Kerman Aloria, Mikel Azkargorta, Félix Elortza, James D. Sutherland, Rosa Barrio, Ugo Mayor, María Luz Martínez-Chantar

“…Abstract The remodeling of the liver proteome, driven by dynamic ubiquitin-like post-translational modifications (PTMs) such as ubiquitination and NEDDylation, is a hallmark of metabolic dysfunction-associated steatotic liver disease (MASLD). …”
Get full text

SCFβ-TrCP targets Ajuba for degradation in a GSK3β-dependent manner in colorectal cancer by Liangshan Li, Feng Zhu, Yupei Liang, Yuanyuan Chen, Yongfu Pan, Lijun Jia, Shiwen Wang, Hu Zhao

“…Overall, our study reveals a novel regulatory mechanism of Ajuba at post-translational level and sheds light on the role of GSK3β-β-TrCP axis in the turnover of Ajuba in CRC.…”
Get full text