Retrospective Analysis of Sacubitril/Valsartan vs Benazepril for Treating Heart Failure Following Acute Myocardial Infarction by Zhao L, Ren Y, Qin D, Yang X, Chen Z, Zhang N

“…The incidence of adverse reactions was comparable between the two groups (P > 0.05).Conclusion: Sacubitril/Valsartan is a safe and effective treatment for heart failure post-AMI, offering significant improvements in cardiac function, inflammatory response, exercise capacity, and a reduction in MACE risk.Keywords: sacubitril/valsartan, heart failure following acute myocardial infarction, efficacy, cardiac function…”
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Molecular modelling and gene expression analysis to probe the GT-γ trihelix transcription factors in Solanum tuberosum under drought stress by Tayyaba Bint Tariq, Faiza Munir, Ishrat Jabeen, Alvina Gul, Rabia Amir

“…Physicochemical analysis highlighted differences in protein properties that could influence their nuclear function. Post-translational modifications further diversified their functionalities. …”
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Microscopic intramural spread in patients with rectal cancer after neoadjuvant chemoradiation by A.E. Verrijssen, E.J. Van Limbergen, M. Bellezzo, H.I. Grabsch, R. Houben, D. Goudkade, J. Melenhorst, I. Samarska, G. Paiva Fonseca, F. Verhaegen, M. Berbee

“…Conclusions: 69% of patients do not retain MIS post-neoadjuvant therapy. Knowledge of tumor thickness seems crucial for patient selection for CXB.…”
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Sleep quality among clinical postgraduate students: a cross-sectional study in Kerala, India by Gopinathan Bhaskaran Gopika, GK Mini, Ameer Ameera, R. Parvathi, P. K. Malavika, Reshma George, Kamala Swarnam, Marthanda Pillai A

“…Those who were having severe stress were more likely to report poor sleep quality compared to their counterparts (adjusted odds ratio (AOR):11.61, CI:1.35–99.39). Medical post graduates were more likely to report poor sleep quality compared to the surgical specialty (AOR: 2.27, CI:1.06–4.87). …”
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Feasibility study protocol: implementing consultation-based high-quality palliative care services in intensive care units by Shin Hye Yoo, Ye Sul Jeung, Yejin Kim, Seyeon Kim, Yoon Sun Jung, Tae Jung Kim

“…The intervention’s potential impact will be assessed by changes in surrogate decision-making conflict, self-efficacy, depression and anxiety, post-decision regret and the experience of patient-centred and family-centred care. …”
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The relationship between hair cortisol and trauma sequelae in motor vehicle crash survivors: the role of childhood trauma experiences by Ileana Schmalbach, Susann Steudte-Schmiedgen, Vanessa Renner, Philipp Drees, Katja Petrowski

“…PDS and IES-R were re-collected three months post-MVC (t2). Elevated pre-MVC HCC predicted PTSD symptoms (p < 0.05), emphasizing the role of chronic stress and HPA axis dysregulation in PTSD. …”
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CORRECTION OF PSYCHONEUROLOGICAL SIGNS OF ACUTE ALCOHOL INTOXICATION IN RATS WITH A NEW ACETYLCYSTEINE-BASED COMPOSITION by D. V. Kurkin, E. I. Morkovin, N. A. Osadchenko, D. A. Bakulin, E. E. Abrosimova, M. A. Dubrovina, N. S. Kovalev, Yu. V. Gorbunova, I. N. Tyurenkov

“…The study was conducted on male Wistar rats. The post-intoxication state was simulated by a single injection of ethanol (3 g/kg, intraperitoneally). …”
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Prevalência dos tipos de fissura em pacientes com fissuras labiopalatinas atendidos em um Hospital Pediátrico do Nordeste brasileiro Prevalence of kinds of cleft lip and palate at... by Moacir Cymrot, Felipe de Castro Dantas Sales, Francisco de Assis Alves Teixeira, Francisco de Assis Alves Teixeira Junior, Geraldo Sérgio Barbosa Teixeira, José Ferreira da Cunha Filho, Natália de Holanda e Oliveira

“…A higher prevalence of trans-incisive foramen cleft in males and post-incisive foramen cleft in girls was observed.…”
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Frequency of periodontal disease in head and neck cancer patients after radiation therapy: a cross-sectional study by Asmaa Abou-Bakr, Enji Ahmed, Hany William, Fatma E. A. Hassanein

“…Conclusions The frequency of periodontitis in the studied sample of HNC patients post RT was 95.08%, reflecting a notably high burden. …”
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Impact of glibenclamide pretreatment on outcomes in acute ischemic stroke patients with type 2 diabetes: a retrospective case-control study by Kaimin Xiao, Ji Tang, Xinwei Yang, Hongmei Chen, Ping Liu, Rongxin He, Lihui Xie, Heling Chu, Yuping Tang, Li Chen

“…Glibenclamide pretreatment in patients with acute ischemic stroke and T2DM may confer clinical benefits by reducing stroke severity and enhancing post-stroke functional outcomes, without increasing adverse events.…”
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Effects of high-intensity multimodal functional training on motor and cognitive functions in people with multiple sclerosis: A study protocol of a pilot randomized controlled trial by Rebecca Cardini, Rita Bertoni, Ilaria Carpinella, Chiara Pegorini, Andrea Tacchino, Erica Grange, Valentina Guidotti, Giampaolo Brichetto, Claudio Solaro, Tommaso Budassi, Tatiana Lanfranco, Marco Rovaris, Davide Cattaneo, Elisa Gervasoni

“…Participants will undergo an extensive evaluation at baseline (T0), post-intervention (T1), and after 2 months at the follow-up (T2). …”
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Evaluation of the Potential of Pyrimidine Nucleoside Antibiotics Against <i>Alternaria</i> spp. Resistant to QoIs Fungicides: Insights for the Management of Ginseng Alternaria Leaf... by Shuai Shao, Mingyuan Hu, Xiaolin Chen, Ming’en Jiang, Changqing Chen, Baohui Lu, Jie Gao

“…On detached ginseng leaves, 300 μg/mL PNA achieved mean protective and curative effects of 87.93% and 94.77% against <i>A. alternata</i> 7 days post-inoculation, outperforming that of 300 μg/mL kresoxim-methyl. …”
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The TUITEK® patient support program improved caregiver-related behaviors on growth hormone treatment adherence by Ekaterina Koledova, Pen-Hua Su, Pen-Hua Su, Yen-Ju Chen, Aria Assefi, Matias Debicki, Debbie Cooke, Amrit Jheeta, Alexander B. Jones, Jung Eun Moon

“…The aim was to assess the impact of the TUITEK® PSP on knowledge, beliefs and perceptions of adherence to r-hGH treatment in high-risk caregivers.Patients and methodsA prospective pre–post research was conducted across the combined population of caregivers of patients with short stature receiving r-hGH treatment in the TUITEK® PSP in Argentina, South Korea, and Taiwan. …”
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Corneal neurotization meets COVID-19: a case report of minimally invasive corneal neurotization complicated by COVID-19-related keratitis by Shuqin Zhuang, Qiaoran Qi, Jiaying Zhang, Jin Li

“…This case underscores the critical need for comprehensive differential diagnosis to rule out infectious etiologies in post-MICN keratitis, ultimately leading to a diagnosis of exclusion for COVID-19-induced disease. …”
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Internet-Delivered Cognitive Behavioral Therapy to Treat Insomnia: A Systematic Review and Meta-Analysis. by Michael Seyffert, Pooja Lagisetty, Jessica Landgraf, Vineet Chopra, Paul N Pfeiffer, Marisa L Conte, Mary A M Rogers

“…Improvements in sleep efficiency, the insomnia severity index and depression scores with internet-delivered cognitive behavioral therapy were maintained from 4 to 48 weeks after post-treatment assessment. There were no statistically significant differences between sleep efficiency, total sleep time, and insomnia severity index for internet-delivered versus in-person therapy with a trained therapist.…”
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The Impact of Cardiovascular Diseases on Postoperative Complications in Orthopedic Trauma Patients by Felix Erne, Larissa Mühlberger, Christoph Ihle, Sabrina Ehnert, Tina Histing, Andreas K. Nüssler, Elke Maurer

“…<b>Conclusions:</b> CVDs play a pivotal role in elevating complication rates post-trauma-surgery. Trauma-related extremity conditions are notably more severe when accompanied by CVD. …”
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Survival outcomes and risk factors for liver and pancreatic metastases in renal cell carcinoma after curative nephrectomy by Kristina Hasselgren, Ali Bencherki, Jennifer Short, Anna Bendler, Yumer Mehriban, Mats Fredrikson, Per-Olof Lundgren, Martin Holmbom

“…Abstract Background Renal cell carcinoma (RCC) has a high recurrence risk, with 20–40% of patients developing metastatic disease post-nephrectomy. This study aimed to identify risk factors associated with liver and pancreatic metastases in patients who have previously undergone curative nephrectomy for RCC. …”
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Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes by Mohammed Usama, Mohammed Usama, Ying Deng, Ying Deng, Yiran Chen, Théa Milland, Théa Milland, Mohan Malleshaiah, Mohan Malleshaiah, Mohan Malleshaiah, Yasaman Aghazadeh, Yasaman Aghazadeh, Yasaman Aghazadeh

“…Recent efforts can be broadly categorized into: (1) improving the cell product as surrogates of native beta cells, (2) promoting engraftment post-transplant to support cell survival, integration into the host, and endocrine function, and (3) developing immunomodulation strategies to reduce or circumvent immunosuppression regimen. …”
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Metabolite patterns of the carbonic anhydrase inhibitors brinzolamide and dorzolamide: potential markers for the route of application by Y Jin, A Thomas, S Gochard, P Delahaut, M Thevis

“…N-desethylation was observed as the main metabolic reaction for both drugs, and metabolite-to-parent drug ratios were determined in all collected post-administration samples alongside drug concentration levels. …”
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Is maternal SARS-CoV-2 infection in the first trimester associated with congenital heart defects? by Athina Samara, Athina Samara, Athina Samara, Conrado Milani Coutinho, Paul T. Heath, Asma Khalil, Asma Khalil, Asma Khalil

“…Additional reports from different parts of the world also highlight post-pandemic increases in specific cardiac anomalies, including ventricular septal defects (VSDs). …”
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