Urinary and plasma donor-derived cell-free DNA for noninvasive monitoring of BK polyomavirus-associated nephropathy in kidney transplant recipients: a prospective cohort study by Luying Guo, Sulin Luo, Rongfang Shen, Pengpeng Yan, Meifang Wang, Tianlu Zhang, Junhao Lv, Guangjun Liu, Hongfeng Huang, Zhimin Chen, Huiping Wang, Wenhan Peng, Jianyong Wu, Jianghua Chen, Rending Wang

“…A total of 224 urine and plasma samples were collected before biopsy and at 1, 2, 3, and 6 months post-biopsy. dd-cfDNA levels were quantified and correlated with histological features and clinical outcomes.Results Urinary dd-cfDNA levels significantly declined in the CISR cohort by month 2 (p < 0.01), preceding changes in creatinine and BKPyV reads. …”
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Evaluation of strength, skin temperature and muscle activation in traditional and eccentric training in Paralympic Powerlifting athletes by Joilson Alves de Souza Leite Júnior, Felipe J. Aidar, Jainara Lima Menezes, Paulo Francisco de Almeida-Neto, Breno Guilherme de Araújo Tinoco Cabral, Ana Filipa Silva, Filipe Manuel Clemente, Georgian Badicu, Fatma Hilal Yagin, Ciro José Brito, Rapahel Fabrício de Souza, Hadi Nobari, Abdullah F. Alghannam

“…Athletes competing nationally and internationally underwent Thermo, Time, and MIF assessments during TT (80%-1RM for both concentric and eccentric phases) and ET (80%-1RM concentric and 110%-1RM eccentric) at pre-training, post-training, 24 h, and 48 h. sEMG was evaluated in the clavicular portion of the pectoralis major (PMCP), sternal portion of the pectoralis major (PMSP), anterior Deltoid (AD), and Triceps Brachii (BT) during the final series (5 sets of 5 repetitions) of a training session. …”
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How Can We Make Scientific Events More Inclusive? Insights From Q&A Sessions and Surveys From an International Conference by Rebecca S. Chen, Tuba Rizvi, Ane Liv Berthelsen, Anneke J. Paijmans, Avery L. Maune, Barbara A. Caspers, Bernice Sepers, Isabel Damas‐Moreira, Isabel Schnülle, Jana Könker, Joseph I. Hoffman, Joelyn deLima, Jonas Tebbe, Kai‐Philipp Gladow, Lisa deVries, Marc Gilles, Nadine Schubert, Nayden Chakarov, Peter Korsten, Petroula Botsidou, Sabine Kraus, Stephen M. Salazar, Svenja Stöhr, Wolfgang Jockusch, Öncü Maraci

“…We addressed further inclusivity barriers of underrepresented minorities beyond gender in a post‐congress survey, which showed that underrepresented minorities did not have a more positive or negative congress experience but did perceive EDI issues as more severe. …”
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Predictors of recurrence after conversion therapy in unresectable hepatocellular carcinoma treated with HAIC, bevacizumab, and sintilimab by Chang-Fu Liu, Xiao-Hui Zhao, Shi-Bo Zhu, Hai-Peng Yu, Wen-Ge Xing, Hui-Kai Li

“…In multivariate analysis, tumor size decline ratio (OR=0.002; 95% CI: 0.000–0.117; p=0.002) and AFP decline ratio (OR=0.240; 95% CI: 0.067–0.862; p=0.029) during conversion therapy independently predicted a lower recurrence risk. Elevated post-therapy bilirubin level remained an adverse predictor (OR=1.020; 95%CI: 1.000–1.030; p=0.039). …”
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Durability of Antibody Responses to SARS-CoV-2 Vaccination over 12 Months in Pediatric Inflammatory Bowel Disease by Sally J. Lawrence, Marina Viñeta Paramo, Frederic Reicherz, Jeffrey N. Bone, Zahra Jama Hussein Shire, Loujain Bilal, Gabriella Guerra, Liam Golding, Pascal M. Lavoie, Kevan Jacobson

“…This study aimed to quantify SARS-CoV-2 antibody responses post vaccination in these immunosuppressed patients over 12 months. …”
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Short Sleep Duration is Inversely Associated with the Prevalence of Underweight in a Young Japanese Population by Ishikawa S, Furukawa S, Miyake T, Yoshida O, Murakami Y, Kanamoto A, Miyazaki M, Shiomi A, Nakaguchi H, Saneto H, Marui K, Kokubu M, Numata Y, Koizumi M, Kato A, Kusumoto K, Kumagi T, Matsuura B, Hiasa Y

“…Sho Ishikawa,1 Shinya Furukawa,2 Teruki Miyake,1 Osamu Yoshida,1 Yoshimasa Murakami,1 Ayumi Kanamoto,1 Masumi Miyazaki,1 Akihito Shiomi,1 Hironobu Nakaguchi,3 Hironobu Saneto,1 Kaori Marui,1 Masahito Kokubu,1 Yuki Numata,1 Mitsuhito Koizumi,1 Aki Kato,2 Katsunori Kusumoto,2 Teru Kumagi,4 Bunzo Matsuura,3 Yoichi Hiasa1 1Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan; 2Health Services Center, Ehime University, Matsuyama, Ehime, Japan; 3Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan; 4Post Graduate Medical Education Center, Ehime University Hospital, Toon, Ehime, JapanCorrespondence: Shinya Furukawa, Health Services Center, Ehime University, Bunkyo, Matsuyama, Ehime, 790-8577, Japan, Tel +81-89-927-9198, Fax +81-89-927-9196, Email furukawa.shinya.mf@ehime-u.ac.jpStudy Objectives: Many studies have shown that sleep disorders including short sleep duration are associated with obesity. …”
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Analysis of the safety and efficacy of microwave ablation of several foci of multiple lung metastases from colorectal cancer by Bohan Song, Jinfeng Bai, Jinmei Zhou, Yinshan Yang, Qijie Wu, Ming Huang, Hongjie Fan, Xianshuo Cheng, Ping Liu, Yu-Dong Xiao, Xin Zhao, Chongying Deng, Shuai Luo, Rong Ding

“…Chest-enhanced CT scans were performed at 1, 3, 6, and 12 months post-MWA to assess ablation outcomes. The primary focus was the median overall survival (mOS), while secondary endpoints encompassed median progression-free survival (mPFS), technical success rates, and safety. …”
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Topical TLR7 agonist and radiotherapy in patients with metastatic breast cancer by Ping Jin, Xiaochun Li, Francesco Marincola, Ena Wang, Sandra Demaria, Davide Bedognetti, Darawan Rinchai, Sylvia Adams, Yelena Novik, Ruth Oratz, David Stroncek, Judith Goldberg, Silvia Chiara Formenti, Maria Fenton-Kerimian, Pascale G Levine

“…These revealed that the presence of a T-helper 1 functional orientation of the tumor microenvironment paralleled by the downregulation of DNA-repair genes was associated with CR after IMQ+RT, but not after IMQ alone. No post-treatment activation of immune-effector functions was observed in stable and progressing lesions.Conclusions Our findings support the safety and clinical efficacy of combining topical IMQ with local RT for recurrent breast cancer, with evidence of local and occasional systemic antitumor activity.Trial registration number NCT01421017.…”
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COMPARATIVE CHARACTERISTICS OF MULTIMORBIDITY, DRUG TREATMENT AND OUTCOMES IN POSTSTROKE PATIENTS WITH ATRIAL FIBRILLATION AND WITH OR WITHOUT HISTORY OF MYOCARDIAL INFARCTION (REG... by E. Yu. Okshina, M. M. Loukianov, S. Yu. Martsevich, S. S. Yakushin, N. P. Kutishenko, I. S. Yavelov, A. N. Vorobyev, K. G. Pereverzeva, A. V. Zagrebelnyy, N. A. Dmitrieva, E. V. Kudryashov, S. A. Boytsov, O. M. Drapkina, K. A. Moseichuk

“…During the four-year period of observation, in comparison with post-stroke patients without a history of MI, the mortality rate for all causes was 1.5 times higher (56.6% and 37.6%, p = 0.0001), the incidence of non-fatal MI was higher (2.0% and 0.3%,p = 0.04). …”
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High-power short-duration vs conventional radiofrequency ablation for atrial fibrillation in patients over 80 years of age: A propensity-score matched cohort analysis by Alex Tunsch Martinez, MD, Raphael Spittler, MD, Nico Erhard, MD, Florian Englert, MD, Jan Syväri, MD, Hannah Krafft, MD, Miruna Popa, MD, Theresa Reiter, MD, Dominic Dischl, MD, Eva Koops, MD, Marta Telishevska, MD, Sarah Lengauer, MD, Gabriele Hessling, MD, Isabel Deisenhofer, MD, FHRS, Fabian Bahlke, MD

“…Propensity score matching revealed 102 pairs for maximizing comparability. A post-ablation 42-day blanking period was applied. …”
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Exploring the Lipid-lowering Effects of Rosa roxburghii Tratt. Alcohol Extract on Diet-induced Obesity Rats through Hepatic Leptin Resistance Pathway by Yi SUI, Tian LU, Minggang TENG, Chaochen YUE, Li YANG, Huifang CHAI

“…Results: Different doses of Rosa roxburghii Tratt. alcohol extract significantly decreased body weight in model group rats at 5 weeks post-administration (P<0.05). By week 8, the treatment significantly lowered Lee's index, serum lipid profiles, and leptin levels in obese rats (P<0.05), with medium- and high-dose groups approaching levels observed in the normal control group. …”
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Psychiatric disorders and mental health care among incarcerated men: A prerelease cross-sectional study in France by Thomas Fovet, Kevin D’Ovidio, Marion Eck, Imane Benradia, Stéphane Duhem, Camille Lancelevée, Pierre Thomas, Marielle Wathelet, Ali Amad

“…The prevalence of mood disorders, anxiety disorders, post-traumatic stress disorder, and psychotic episodes were 30.7% (95% confidence interval [CI]: 27.1%–34.6%), 28.7% (95% CI: 25.1%–32.5%), 11.1% (95% CI: 8.8%–13.9%), and 10.5% (95% CI: 8.3%–13.3%), respectively. …”
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Reflections on youth partnership in a randomized controlled trial of an intervention to optimize transition from pediatric to adult care in inflammatory bowel disease by Brooke Allemang, PhD, MSW, RSW, Ashleigh Miatello, MA, Pranshu Maini, Joshua Eszczuk, Claudia Tersigni, MSc, Samantha Micsinszki, PhD, Sneha Dave, Natasha Bollegala, MD, MSc, FRCPC, Nancy Fu, MD, MHSc, Kate Lee, PhD, MBA, Samantha J. Anthony, PhD, MSW, RSW, Melanie Barwick, PhD, Eric I. Benchimol, MD, PhD

“…Results: The processes, outputs and impacts of AYAs’ contributions in priority setting and planning, intervention design and refinement, study execution, dissemination, and post-trial intervention implementation and dissemination were identified. …”
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Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. by Patrick Y Sips, Xu Shi, Gabriel Musso, Anjali K Nath, Yanbin Zhao, Jason Nielson, Jordan Morningstar, Amy E Kelly, Brittney Mikell, Eva Buys, Vikhyat Bebarta, Jared Rutter, V Jo Davisson, Sari Mahon, Matthew Brenner, Gerry R Boss, Randall T Peterson, Robert E Gerszten, Calum A MacRae

“…We found that zebrafish embryos in the first 3 days post fertilization (dpf) are highly resistant to cyanide, becoming progressively more sensitive thereafter. …”
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Dynamic Monitoring of CD200 Mediated by Ascites-Derived Exosomes as a Predictor of Survival and Response to Front-Line Chemotherapeutics in Advanced High-Grade Serous Ovarian Cance... by Ying Ji, Shanshan Liu, Genju Wang, Xin Chen, Yujuan Li, Xiaogai Zhi, Hongxiu Jiang, Juan Tang, Yi Ding, Shuli Zhao, Hongmei Zhou, Aiwei Xiong

“…Methods: We performed dynamic measurements of exosome-mediated or serum CD200 levels at primary diagnosis, post-operation, and three cycles after chemotherapy. …”
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Correlation Between the Online Visiting Time and Frequency Increase in Telemedicine Services Offered by Health Care Providers Before, During, and After the COVID-19 Pandemic in Chi... by Weiyi Wang, Yuntian Chu, Fangfang Cui, Xiaobing Shi, Xu Zhang, Dongxu Sun, Jinming Shi, Jie Zhao

“…However, what role telemedicine will play post–COVID-19 is still uncertain. ObjectiveWe aimed to determine the frequency change in health care providers offering telemedicine services before, during, and after COVID-19, as well as the correlation between the frequency change and telemedicine visit time. …”
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Utilizing Sargassum polycystum as Co-Feedstock to Enhance Methane Yield from Pig Dung in Anaerobic Digestion by Earl Francis A Busilaoco, Wendyl M Aligato, Jan Nico R Gaslang, Hyrn G Almoroto, Kristine Yhuri A Libreta, Mervy Aretha Deon L Loon, Camella A Redulla, Darius Miguel Pederes, Angela Glaiza B Pingcas, Rovie Joice M Durante, Ricksterlie C Verzosa

“…The pretreated group exhibited the highest methane concentration (>9,999.00 ppm), followed by the untreated group (8,931.75 ppm), while the control group produced the lowest yield (3,644.25 ppm). Post hoc analysis confirmed a significant difference in methane yield in the pretreated group compared to the control (p = 0.010). …”
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Renal function in liver recipients: in-depth analysis of data from the Local Scientific Transplant Registry of the Burnasyan Federal Medical Biophysical Center by A. I. Sushkov, V. S. Rudakov, M. V. Popov, A. E. Kalachyan, E. V. Naydenov, A. I. Artemiev, S. E. Voskanyan

“…Particular attention should be paid to elderly patients, with arterial hypertension, reduced baseline eGFR, post-LT AKI RIFLE &gt; I (especially in combination with EAD). …”
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Spleen Infarction in Plasmodium Infection by Vitorino Modesto dos Santos, Andressa Plaça Tedeschi, Julia Campos Modesto

“…The patient evolved with stable hemodynamic status and did not need emergency surgery; malarial trophozoites were not observed on the peripheral blood smear post-treatment [3]. A 30-year-old man with the diagnosis of P. falciparum infection underwent artemether-lumefantrine, and presented with upper left abdominal pain; the abdominal images revealed splenomegaly with a hypoechoic lesion confirmed as a splenic infarction [4]. …”
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Pneumonitis after normofractionated radioimmunotherapy: a method for dosimetric evaluation by Kim Melanie Kraus, Caroline Bauer, Lisa Steinhelfer, Benedikt Feuerecker, Juliana Cristina Martins, Julius Clemens Fischer, Kai Joachim Borm, Jan Caspar Peeken, Denise Bernhardt, Stephanie Elisabeth Combs

“…Abstract Background Post-Therapy-Pneumonitis (PTP) is a critical side effect of both, thoracic radio(chemo)therapy (R(C)T) and immune checkpoint inhibition (ICI). …”
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