Plasminogen deficiency reduces disease severity and immune responses in enterovirus A71-infected mice by Zheng-Xun Li, Ya-Fang Wang, Li-Ting Chiang, Li-Jin Hsu, Shih-Min Wang, Jen-Ren Wang, Hua-Lin Wu, Shun-Hua Chen, Chuan-Fa Chang

“…The viral loads in the spinal cord of PLG knockout mice were lower than those in WT mice 6 days post-infection. EV-A71-associated cytokines such as IL-1β, IL-6, MCP-1, IL-10, and IFN-γ were investigated. …”
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Recurrence and influencing factors of moderate-to-severe atopic dermatitis after dupilumab withdrawal: a retrospective cohort analysis by Maohua Chen, Xinyu Wen, Jie Liu, Ge Yang, Qingqing Li, Zhiyuan Jiang, Xinjie Zhang, Zhen Cai, Lixia Zhang

“…These findings confirm the disease characteristic of AD’s susceptibility to relapse and emphasize the need for individualized treatment, post-discontinuation monitoring, and long-term standardized management of AD patients with different risk factors for relapse.…”
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Status and prospects of research on HCl removal from blast furnace gas by Gang LU, Yi XING, Hualong ZHOU, Liqianxin QIAN, Lin DING, Qiulin ZHANG, Tingshuang LENG, Wei SU, Rongzhi ZHAO

“…Additionally, the high cost of this technology presents a significant economic burden for large-scale implementation. While post-TRT alkali spray dechlorination effectively protects gas pipelines and equipment after the alkali spray tower, it does not address salt buildup on the TRT blades or the corrosion of gas pipelines between the TRT and the alkali spray tower. …”
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Impact of vein-to-vein time in patients with R/R LBCL treated with axicabtagene ciloleucel by Frederick L. Locke, Tanya Siddiqi, Caron A. Jacobson, Sarah Nikiforow, Sairah Ahmed, David B. Miklos, Yi Lin, Matthew A. Lunning, Brian T. Hill, Armin Ghobadi, Zhen-Huan Hu, Michael T. Hemmer, Michael J. Zoratti, Suresh Vunnum, Jonathan Tsang, Clare Spooner, Harry Smith, Christine Fu, Anik Patel, Harry Miao, Shilpa A. Shahani, Debbie L. Mirjah, Hairong Xu, Marcelo C. Pasquini

“…The impact of V2Vt (<28 days vs ≥28 to <40 days vs ≥40 days) on effectiveness and safety outcomes was evaluated in patients treated with axi-cel enrolled in a post-authorization safety study using the Center for International Blood and Marrow Transplant Research data. …”
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Agronomic potential of water hyacinth (Eichhornia crassipes) based organic-phosphate liquid fertilizer on strawberry growth, yield and fruit quality in contrasting soil types by Joyce Nababi, Bruno Kokouvi Kokou, John Finias Kamanula, Fednand Paul Wanjala, Milliam Nakawoombe, Issa Balde, Georges Lufungula Alunga, Elijah Malinga Menard Wanda

“…Vegetative growth, yield and quality-related parameters were analysed using analysis of variance (ANOVA), complemented by Tukey’s HSD post hoc tests (p < 0.05). Our results showed that B treatments significantly enhanced vegetative traits, with the highest plant height 11.80 ± 1.04 cm and leaf area 70.31 ± 3.55 cm² in sandy loam soil (B1:25 %). …”
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Seroconversion Is Misleading as a Test for HSV-2 Infection in Prophylactic Genital Herpes Vaccine Trials: Results of Vaccine Studies in Guinea Pigs by Valerie Bromberg, Lauren M. Hook, John M. Lubinski, Zauraiz Syeda, Kevin P. Egan, Gary H. Cohen, Sita Awasthi, Harvey M. Friedman

“…In the second analysis, we considered animals to be infected if they had positive virus cultures from vaginal swabs obtained on day two or four post HSV-2 inoculation. In the third analysis, we considered animals to be infected if they had any condition included in the first two analyses. …”
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A Single-Chain Mpox mRNA Vaccine Elicits Protective Immune Response in Mice by Qian Xu, Rong-Rong Zhang, Mei Wu, Jie Zhang, Zu-Xin Wang, Hang Chi, Chao Zhou, Xiao-Chuan Xiong, Hai-Tao Liu, Cheng-Feng Qin, Qing Ye

“…Importantly, MPXV^eM1-eA35 demonstrated protective efficacy in a VACV challenge mouse model and showed superior capacity in preventing weight loss post-challenge compared to MPXV^eM1+eA35. …”
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Comparison of pilot tone-triggered and electrocardiogram-triggered cardiac magnetic resonance imaging: a prospective clinical feasibility study by Xianling Qian, Yali Wu, Peter Speier, Caixia Fu, Yunzhu Wu, Lude Cheng, Yinyin Chen, Shiyu Wang, Caizhong Chen, Kai Liu, Ling Chen, Hang Jin, Mengsu Zeng

“…Imaging included T2-weighted imaging (T2WI), T1-mapping, T2-mapping, cine, late gadolinium enhancement (LGE), and post-contrast T1-mapping sequences. Image quality and quantitative measurements were evaluated, including T2WI signal intensity, native T1-mapping, T2-mapping, and extracellular volume fraction (ECV) values, and comparative signal-to-noise ratio (compSNR) and comparative contrast-to-noise ratio (compCNR) of cine and LGE images, left/right ventricular function. …”
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Training the trainers and disseminating information: a strategy to educate health professionals on epilepsy Capacitações e multiplicadores: uma estratégia para educação de profissi... by Paula T. Fernandes, Ana L.A. Noronha, Josemir W. Sander, Gail S. Bell, Li M. Li

“…For the evaluation of this process, health professionals completed a quantitative and qualitative questionnaire to assess their knowledge, attitudes and perception (KAP) of epilepsy prior to the training (pre-test) and 6 months after it (post-test). RESULTS: Comparison of knowledge scores prior to (mean=55.8, standard deviation=14.0) and after (mean=71.5, standard deviation=12.0) the intervention showed that physicians had improved knowledge after the training (t-test=7.8, p<0.001). …”
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Protective effects of Cordyceps militaris against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet by Wan-Ting Tsai, Wan-Ting Tsai, Jiro Hasegawa Situmorang, Wei-Wen Kuo, Wei-Wen Kuo, Wei-Wen Kuo, Chia-Hua Kuo, Shinn-Zong Lin, Shinn-Zong Lin, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Chih-Yang Huang, Tsung-Jung Ho, Tsung-Jung Ho, Tsung-Jung Ho, Tsung-Jung Ho

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Surgical management of axis' traumatic spondylolisthesis (Hangman's frature) Tratamento cirúrgico para a espondilolistese traumática do áxis (fratura do enforcado) by José Luiz Romeo Boullosa, Benedicto Oscar Colli, Carlos Gilberto Carlotti Jr, Koji Tanaka, Marcius Benigno Marques dos Santos

“…RESULTS: Nine patients had a good post surgery evolution with satisfactory consolidation of the fractures and disappearance of the symptoms. …”
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The impact of the COVID-19 pandemic on maternal healthcare costs: a time series analysis of pregnancies of multi-ethnic mothers in South London, United Kingdom by Alice McGreevy, Marina Soley-Bori, Florence Tydeman, Kathryn V. Dalrymple, Sara L. White, Asma Khalil, Lucilla Poston, Emma L. Duncan, Tisha Dasgupta, Hiten D. Mistry, Julia Fox-Rushby, Peter von Dadelszen, eLIXIR-BiSL Partnership, RESILIENT Study Group, Laura A. Magee

“…Monthly costs increased with first lockdown for Black (£103 [£26 to 181]) and Asian women (£128 [£38 to 218]) and increased more slowly during post-lockdown (£ − 12 [£ − 23 to − 2]), for Asian women, remaining higher throughout the pandemic for Black and Asian women compared with White women. …”
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Investigating the hemodynamic response to iTBS of the left DLPFC: A concurrent iTBS/fNIRS study by Adam W.L. Xia, Minxia Jin, Bella B.B. Zhang, Rebecca L.D. Kan, Tim T.Z. Lin, Penny P. Qin, Xiao Wang, Wanda M.W. Chau, Nancy M.X.Y. Shi, Priya Kannan, Erin Y. Lu, Tifei Yuan, Jack Jiaqi Zhang, Georg S. Kranz

“…Conclusion: This study revealed a pronounced increase in HbR during iTBS in the stimulated DLPFC, alongside decreased HbR contralaterally both during and post-stimulation. Furthermore, our study highlights the importance of individual factors in understanding iTBS effects on cortical excitability.…”
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Brain-based gene expression and corresponding behavioural relevance of risk genes for broad antisocial behaviour by Jaroslav Rokicki, Megan L. Campbell, Dennis van der Meer, Alina I. Sartorius, Natalia Tesli, Piotr Jahołkowski, Alexey Shadrin, Ole Andreassen, Lars T. Westlye, Daniel S. Quintana, Unn K. Haukvik

“…Our investigation of fifteen genes associated with ASB examined their biological role and distribution across tissues, integrating post-mortem brain sample data from the Allen-Human-Brain Atlas and the Genotype-Tissue Expression project. …”
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Core fucosylation of IL-2RB is required for natural killer cell homeostasis by Harrison Sudholz, Xiangpeng Meng, Hae-Young Park, Zihan Shen, Iva Nikolic, Joseph Cursons, Ethan D. Goddard-Borger, Iona S. Schuster, Christopher E. Andoniou, Mariapia A. Degli-Esposti, Nichollas E. Scott, Michael Chopin, Jai Rautela, Sebastian Scheer, Nicholas D. Huntington

“…Summary: Natural killer (NK) cell homeostasis and effector functions require context-dependent signaling via numerous receptors, including the interleukin-15 receptor (IL-15R). Post-translational modifications can regulate receptor signaling, impacting receptor turnover and trafficking. …”
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Accuracy and cost comparison of 3D-printed guides in complex spinal deformity correction: direct vs indirect design by Wei Yang, Wei Yang, Wei Yang, Wei Guo, Wei Guo, Wen-Jun Wu, Rong Ma, Zemin Wang, Honglai Zhang, Wanzhong Yang, Zhaohui Ge, Zhaohui Ge

“…Screw placement and osteotomy were simulated using 3D-printed spinal models and guides. Post-operative CT scans were performed on the models and compared with pre-operative designs to evaluate the accuracy, efficiency, cost, and clinical practicality of different guides during screw placement and osteotomy.ResultsThis study included 10 patients with complex spinal deformities (Five males and five females, with an average age of 37 years), covering five diagnostic types such as neurofibromatosis and adult idiopathic spinal deformity. …”
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A set of plasmatic microRNA related to innate immune response highly predicts the onset of immune reconstitution inflammatory syndrome in tuberculosis co-infected HIV individuals (... by Polidy Pean, Ratana Meng, Eliott Benichou, Eliott Benichou, Pichsivannary Srey, Bunnet Dim, Laurence Borand, Laurence Borand, Olivier Marcy, Didier Laureillard, François-Xavier Blanc, Tineke Cantaert, Yoann Madec, Laurence Weiss, Daniel Scott-Algara

“…MicroRNAs, small molecules of approximately 22 nucleotides, which regulate post-transcriptional gene expression and their profile has been proposed as a biomarker for many diseases. …”
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Serum cholinesterase combined with platelet-to-hemoglobin ratio for predicting survival prognosis in stage I-III colorectal cancer patients undergoing radical surgery: a retrospect... by Luyu Huang, Kai Zhao, Hongnan Lu, Wei He, Dazhuang Miao, Yan Wang, Bingcai Li, Qi Wang, Shixiong Jiang, Yunhe Jia

“…The CHE-PHR indicator serves as an independent prognostic factor for stage I-III CRC patients post-surgery, aiding in predicting recurrence and metastasis.…”
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Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory... by Andrea D. Olivas, Paul Chak Mou Ngai, Emily Schahrer, Junjie Xing, Mobarakeh Ghadiri, Kinga S. Olortegui, John F. Cursio, Shintaro Akiyama, Eugene B. Chang, Le Shen, Konstantin Umanskiy, David T. Rubin, David Zemmour, Christopher R. Weber

“…Results: The 18-year pouch failure risk was 23%, with post-procedure clinical features of Crohn’s disease as a major risk factor (hazard ratio [HR], 4.3; 95% confidence interval [CI], 2.3–8.1) as well as high-risk histologic features, including deep chronic inflammation (HR, 21; 95% CI, 11–41) and severe disease activity (HR, 14; 95% CI, 5.7–32) in TAC specimens. …”
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Tijela u tranziciji: transnacionalna ekonomija i nacionalna zajednica u <em>Neuromanceru</em> i <em>Cosmopolisu</em> by Sven Cvek

“…Sličnu tezu o "transnacionalnosti" SAD-a kao posljedici globalne cirkulacije kapitala nudi i Frederick Buell u svojoj analizi preobrazbe američkoga nacionalizma u “post-nacionalnom” dobu (neoliberalne) globalizacije. …”
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