Derivation and internal–external validation of clinical prediction model for postoperative clinically important hypotension in patients undergoing noncardiac surgery: an internatio... by Stephen Su Yang, German Malaga, Maria Lazo-Porras, Patricia Busta-Flores, Aida del Carmen Rotta-Rotta, Pavel S. Roshanov, Daniel I. Sessler, Amal Bessissow, Thomas Schricker, Vicky Tagalakis, Diane Heels-Ansdell, Shirley Pettit, P.J. Devereaux

“…The postoperative period was defined from the Post-Anesthesia Care Unit to hospital discharge. …”
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Treadmill Training Increases SIRT-1 and PGC-1α Protein Levels and AMPK Phosphorylation in Quadriceps of Middle-Aged Rats in an Intensity-Dependent Manner by Nara R. C. Oliveira, Scherolin O. Marques, Thais F. Luciano, José R. Pauli, Leandro P. Moura, Erico Caperuto, Bruno L. S. Pieri, Julia Engelmann, Gisele Scaini, Emilio L. Streck, Fabio S. Lira, Ricardo A. Pinho, Eduardo R. Ropelle, Adelino S. R. Silva, Cláudio T. De Souza

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Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke by Filippo Cotellessa, William Campanella, Luca Puce, Maria Cesarina May, Marta Ponzano, Riccardo Picasso, Matteo Mordeglia, Davide Subbrero, Ester Cecchella, Laura Mori, Davide Sassos, Massimo Del Sette, Matteo Formica, Carlo Trompetto

“…This longitudinal study aimed to investigate the clinical and ultrasound characteristics of HSP emerging within the first 72 h (T0) post-stroke, with follow-ups at one month (T1) and three months (T2). …”
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Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation by Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu

“…The average percentage of elicited electrodes (eABR%) during the operation is 72.73±17.99%. Post‐activation, hearing and speech outcomes improved steadily. …”
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Analysis of failure mechanisms and behavior of LiCoO2-graphite batteries at 0 ℃ by Ke Li, Jia Niu, Yifan Hao, Jiaxin Yao, Pushpendra Kumar, Zhenhao Luo, Songtong Zhang, Jing Wang, Xiayu Zhu, Wenjie Meng, Jingyi Qiu, Guiling Wang, Hai Ming

“…Through the analysis of differential voltage and incremental capacity curves, along with post-mortem analysis after cycling, it is revealed that the desolvation energy of lithium largely determines whether lithium integrates into the active materials or plates on the electrode surface. …”
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Exploring Aneurysmal Bone Cysts of the Skull: Insights from a Review of the Literature and a Case Report by Flavio Panico, Leonardo Bradaschia, Pasquale Cardellicchio, Fabio Cofano, Enrico Lo Bue, Stefano Colonna, Alberto Morello, Andrea Bianconi, Diego Garbossa, Gianluca Piatelli, Marco Pavanello

“…Secondary lesions showed a higher frequency of complications within the first months post-surgery (<i>p</i> = 0.041). <b>Conclusions</b>: No significant correlation was found between ABCs and fibrous dysplasia (FD) or head trauma. …”
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Study protocol for assessing the effectiveness, implementation fidelity and uptake of attachment & child health (ATTACH™) Online: helping children vulnerable to early adversity by Nicole Letourneau, Lubna Anis, Cui Cui, Ian D. Graham, Kharah Ross, Kendra Nixon, Jan Reimer, Miranda Pilipchuk, Emily Wang, Simone Lalonde, Suzanna Varro, Maria Jose Santana, Ashley Stewart-Tufescu, Angela Soulsby, Barbara Tiedemann, Leslie Hill, Tiffany Beks, Martha Hart

“…Effectiveness outcomes examine children’s development and mental health, parent–child relationships, and RF, measured before, after, and 3 months post-intervention. Implementation outcomes include fidelity and uptake of ATTACH™ Online, assessed via tailored tools and qualitative interviews using NPT, with parents, health care professionals, and administrators from agencies. …”
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Diagnostic Effectiveness of Transforming Growth Factor Beta 1 in Assessing the Risk of Developing Graft Dysfunction in Liver Recipient Children by R. M. Kurabekova, O. M. Tsiroulnikova, I. E. Pashkova, A. G. Olefirenko, O. E. Gichkun, L. V. Makarova, R. A. Monakhov, P. O. Shevchenko

“…The TGF-β1 concentration in plasma was determined using ELISA on average 3 ± 2 days prior to liver transplantation and in the early post-transplant period.Results. The level of TGF-β1 in the blood of children with liver cirrhosis was lower than in healthy children (p = 0.001). …”
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The donor management algorithm in transplantation of a composite facial tissue allograft.. First experience in Russia by V. V. Uyba, K. K. Gubarev, S. E. Voskanyan, M. A. Volokh, V. L. Vinogradov, N. V. Kalakutskiy, G. G. Khubulava, A. I. Zakhlevnyy, I. Yu. Murashov, A. F. Lesnyakov, E. S. Romanova, V. A. Shcherbakov, V. V. Aleksandrov, A. S. Samoylov, M. V. Zabelin

“…Establishing of facial VCA transplantation Program is a complicated process for transplant centers and can hardly be implemented without a properly organized post-mortem organ donation system at a national level. …”
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Outcomes of Different Lifestyle Approaches in a Multicentre, Open-Label, Parallel-Group, Randomised Controlled Trial of the Effectiveness of Integrating a Pragmatic Pathway for Pre... by Werd Al-Najim, Babak Dehestani, Ahmed W. Al-Humadi, Danielle H. Bodicoat, Dimitris Papamargaritis, Michael Lean, Barbara McGowan, David R. Webb, John PH Wilding, Melanie J. Davies, Carel W. le Roux

“…<b>Background/Objectives:</b> The STRIVE study was a multicentre, open-label, real-world clinical trial evaluating the effectiveness of a targeted prescribing pathway for liraglutide 3.0 mg as an adjunct to standard care versus standard care alone in people with obesity attending Specialist Weight Management Services (SWMS) in the UK and Ireland. This post hoc analysis focuses on the standard care arm to explore differences in outcomes between sites, particularly the potential impact of offering meal replacements as part of usual care. …”
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Unraveling Genomic and Pathogenic Features of <i>Aeromonas ichthyocola</i> sp. nov., <i>Aeromonas mytilicola</i> sp. nov., and <i>Aeromonas mytilicola</i> subsp. <i>aquatica</i> su... by Nihed Ajmi, Muhammed Duman, Batuhan Coskun, Ceren Esen, Oner Sonmez, Gorkem Tasci, Orkide Coskuner-Weber, Hilal Ay, Digdem Yoyen-Ermis, Artun Yibar, Andrew P. Desbois, Izzet Burcin Saticioglu

“…Further genomic analyses identified biosynthetic gene clusters for nonribosomal peptides (NRPs) and ribosomally synthesized and post-translationally modified peptides (RiPPs), which often have roles in secondary metabolite production. …”
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Prediction of long-term major adverse cardiac events after myocardial infarction: value of combination of inflammatory biomarkers and GRACE score by Dan Tian, Nianxi Yu, Tianxiao Mao, Yanli Li, Ruiyan Liu, Ye Xu, Dong Huang, Qianzhou Lv, Kunming Pan, Kunming Pan

“…The primary endpoint was the post-MI occurrence of a composite of major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal MI, and non-fatal ischemic stroke. …”
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Comparative Effectiveness of Different Frequencies of Spinal Cord Stimulation for the Treatment of Patients with Failed Back Surgery Syndrome: Systematic Review and Network Meta-An... by Qin YY, Zhang CP, Tang SS, Wu JP, Zhu LX, Li YH, Xu F

“…Yuan Yuan Qin,1,2,&amp;ast; Chun Pan Zhang,1,2,&amp;ast; Shun Song Tang,1,2 Jiang Ping Wu,1,2 Li Xuan Zhu,1,2 Yan Hua Li,1,2 Fei Xu1,2 1Department of Pain Management, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, People’s Republic of China; 2The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Fei Xu, Department of Pain Management, The First People’s Hospital of Yunnan Province, 157 Jinbi Road, Kunming, 650032, People’s Republic of China, Email 494428530@qq.comPurpose: Failed back surgery syndrome (FBSS) is a common and challenging complication after lumbar spine surgery, with around 30% of patients experiencing this condition post-surgery. Spinal cord stimulation (SCS) is a prevalent treatment for FBSS, yet there is a lack of systematic comparisons among different SCS frequencies. …”
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Changes in Blood Eosinophil Counts Predict the Death of Patients With Myocardial Infarction After Hospital Discharge by Kaiyang Lin, Manqing Luo, Xia Gu, Jun‐Yan Xu, Jinwei Tian, Peter Libby, Guo‐Ping Shi, Junli Guo

“…Dynamic changes of blood eosinophil counts offer a more accurate prediction of post‐myocardial infarction deaths than a single time point data analysis.…”
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Non-inferiority comparison of medical glue and hook-wire for preoperative localization of multiple pulmonary nodules by Zexin Xie, Zexin Xie, Ran Ma, Ran Ma, Tao Gao, Tao Gao, Jingsong Liu, Jingsong Liu, Kewei Zhang, Kewei Zhang, Jun Li, Jun Li, Xiaotong Zhou, Xiaotong Zhou, Hao Zhang, Hao Zhang

“…Furthermore, compared to hook-wire, medical glue was associated with a lower incidence of pneumothorax and pulmonary hemorrhage, as well as reduced pain scores at 2 h post-localization.Clinical Trial Registrationhttps://www.chictr.org.cn, identifier (ChiCTR2400080040).…”
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Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma by Bartimée Galvan, Loïc Ongena, Jonathan Bruyr, Gregory Fettweis, Eva Lucarelli, Arnaud Lavergne, Emeline Mariavelle, Tina M. O’Grady, Zahrat El Oula Hassoun, Margaux Claes, Laurence Dubois, Kevin A. W. Lee, Véronique Kruys, Cyril Gueydan, Jules Durand, Eric Hervouet, Florian H. Geyer, Ana Banito, Roland Imle, Lianghao Mao, Ashok K. Jayavelu, Thomas G. P. Grünewald, Florencia Cidre-Aranaz, Jean-Claude Twizere, Franck Dequiedt

“…Our findings uncover a post-transcriptional function of EWSR1::FLI1 and suggest that targeting mRNA stability mechanisms may offer therapeutic opportunities for EwS.…”
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Improved functional outcomes and cost benefits of door-to-needle time under 30 min in acute ischemic stroke: an observational study by Jia Dong James Wang, Ying-Qiu Dong, Joshua Y. P. Yeo, Kevin Soon Hwee Teo, Shiyang Ng, Mingxue Jing, Bernard P. L. Chan, Leonard L. L. Yeo, Magdalene L. J. Chia, Louis Widjaja, Lily Y. H. Wong, Pamela Lim, Shikha Kumari, Diarmuid Murphy, Hock-Luen Teoh, Benjamin Y. Q. Tan

“…Multivariate linear and logistic regressions were performed to evaluate impact of DTN time on functional and financial outcomes, including modified Rankin's Score (mRS) at 3-months post-AIS, length-of-stay (LoS), total hospitalization cost, symptomatic intracerebral hemorrhage (SICH) and inpatient mortality.Results1,146 patients (62.0% male) with mean age of 68.6 years were included. …”
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Results of a study of the effectiveness of direct coronary oxygen persufflation as a donor heart conditioning method by M. O. Zhulkov, D. A. Sirota, I. S. Zykov, A. K. Sabetov, K. A. Agaeva, А. G. Makaev, D. M. Osintsev, A. P. Nadeev, V. Е. Kliver, E. E. Kliver, A. M. Volkov, A. R. Tarkova, А. V. Fomichev, A. M. Chernyavsky

“…After 3 hours of donor heart preservation, orthotopic heart transplantation (OHTx) was performed. In the post-transplant period, we studied central hemodynamic parameters, myocardial oxygen consumption, level of myocardial ischemia markers (troponin I, TnI; creatine phosphokinase-MB, CPKMB; lactate dehydrogenase, LDH), and histological signs of structural cellular injury. …”
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NIPT of Maternal Plasma-Originated cfDNA: Applications and Guide for the Implementation by Fernández Martínez FJ, Gil Mira MM, González González C, Madrigal Bajo I, Oancea Ionescu R, Orellana Alonso C

“…It addresses key aspects such as technical and analytical requirements, integration with invasive diagnostic methods, pre- and post-test genetic counseling, and legal considerations. …”
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Finite element model-based evaluation of the effectiveness of the incisional skinbridge procedure for posterior horseshoe perianal abscess by Shi Rong, Wang Jing, Ke Minhui, Chen Zuqing, Huang Juan, Chen Riqi, Wang Zhaochu

“…Six pivotal nodes were selected for model validation, followed by comparisons of displacement disparities between the two models and an evaluation of anal pressure three months post-surgery. [Results] Displacements measured surgically at 174 nodes in the standard skin-bridge group and 173 nodes in the wide skin-bridge group significantly deviated from the model prediction (P<0.05), whereas other nodes displacements measured surgically aligned with the model (P>0.05). …”
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